<?xml version="1.0" encoding="UTF-8"?><protein-matches xmlns="http://www.ebi.ac.uk/interpro/resources/schemas/interproscan5" interproscan-version="5.54-87.0">
  <protein>
    <sequence md5="fcc230e8156b4c8a9c654c09013a09c1">MGNSCSSGQGHKDKDNMSQRSEESGSYQIRASLPSDKQQVLMNHVTHTGGVLLEPSTAGQQAIQQVSNATTPSTGNEKKVPSKILRGIAAPSVSDSLSLSSPPGIVSPRDLIIDGNVPPELASLSEQLQNLLMGKVSFAKTASKTRKIVIYVCAADSQDCCVEKGALHNALYPELRARCRLKGYELHIVDLHWKTLLEKQQDHEFPELCIGELTRQMEVAYVIPVLFLNNSLGTPLLPISIECSDFQMAMNSVEDQSAQSLLSKWYKLDEAAQPPCYRLQSTSSHIPGFKETSTEDREKALEEWQSEIERMLVVLINVFSQELRDTYLTTVVEQEVHNTVFMSQELAKRCIWINRVYTPGEKTTNEPPSPGESEHFRRLNILQRDLRNQLAEKHIVRLPVKYVDGGLNMEIPEHAQYISQVLGHMNKHLTEMIDAIIDEHQSKNILKPSYGIDTSIFEELNQQTTFCQKAAQCSVNREKTISDIKNYILTENHSPLVIYGPGGCGKTTLLARIAQCTSQWLPESFLVLRFVGISAQSSTIEQLLSSITHQCSILTYGHKSSVAHTIDNYKNALPNLLMASCMQRPLIVVLDGIEQVKMYSSKVIDWLPLQLPDNIKLIISVSENSDIYKDMVKVIPEESFIRMPVLGELEAKGILMSSVMQYNHSVNSKIQDCVLKSVQECTLPLYTKVLAWQTSWWADKENVIVPKGQVDDQLTLMLEELETILGQNQVEHALAIMTSTKHGITDSEMLDLLAHDEIFQNNTTYVSWAPACLAWSRLNKHLAPFLQWTLTGTVLGVQWRDNMLLQAVKKRYKSYSNWAHEMLFNYYNGKWWSEQPQANLSARLISQDTLLGTCYNRRKLDELPYHYYYLHGSEKLSSSDYLNDLNWIYDKVCGSNCFQLLEDIHLCKQEGISLNESVAVLQSFLETYVNVLNYDGRQFYSQFYSFLSMLQPKGEDICSDIFSICKDPPIPSLIPNYCLDIAVEDEHATKRRKAYDLIVRLPETHQFVACISTEDEQISVWNAARWERVRLLKGIPHPTNLVPINQHKCIVLCQRELRIYDLNTGTFLTKLKGVMNQKMPYYGLHDASHLVALSRNRMYVNLMNLETGDCVTTFKAGEDRFLNSLLVSGDGRVLVCGDETQKPFPLLVWNLQSRKLLYDLRIPHHDFITSLSAITYEGNYVCCVCHEIDEPNPNFIVVYDLQSGTLFKKWKPSCDTVSLEISSQGGCVISGLEDARILVWDLITGNCRWTLEGHTAPVNYLRLEPRGVLFLSTDIQGRDKSIRVWDLNKGNLVAVYTTSLNITTCDMSLQGQTIILSMEGCEELVFLKLRGPGVEETIEELEVPYGDPEIDFAEFDLSESGAC</sequence>
    <xref id="XP_017775485.1" name="XP_017775485.1 PREDICTED: NACHT and WD repeat domain-containing protein 2 isoform X1 [Nicrophorus vespilloides]"/>
    <matches>
      <hmmer2-match evalue="1.9E-11" score="54.0">
        <signature ac="SM00320" name="WD40_4">
          <entry ac="IPR001680" desc="WD40 repeat" name="WD40_repeat" type="REPEAT">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-RNO-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6803207" name="TP53 Regulates Transcription of Caspase Activators and Caspases"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DME-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CFA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-SCE-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-SPO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DME-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DRE-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-BTA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DRE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-CEL-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-SSC-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-390471" name="Association of TriC/CCT with target proteins during biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DRE-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DRE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-BTA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7831" name="ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-DME-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-RNO-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-SCE-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-CFA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-XTR-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CEL-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-CFA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-DRE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-GGA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-1362277" name="Transcription of E2F targets under negative control by DREAM complex"/>
            <pathway-xref db="Reactome" id="R-GGA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-RNO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-SPO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-MMU-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-432620" name="Dephosphorylation of PER"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SPO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-MMU-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-HSA-168271" name="Transport of Ribonucleoproteins into the Host Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-HSA-163359" name="Glucagon signaling in metabolic regulation"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6841" name="homophytochelatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-BTA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-GGA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-DME-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-DRE-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DME-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DRE-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CEL-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DRE-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SCE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DME-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-BTA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CEL-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CFA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-GGA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-SSC-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-RNO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-BTA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-DDI-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DME-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6289" name="petrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-BTA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DME-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-HSA-112314" name="Neurotransmitter receptors and postsynaptic signal transmission"/>
            <pathway-xref db="Reactome" id="R-DDI-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CEL-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-DRE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SSC-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-168325" name="Viral Messenger RNA Synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-SCE-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-DME-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-MMU-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-BTA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-BTA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-XTR-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-GGA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DDI-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-BTA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-6463" name="peptidoglycan cross-bridge biosynthesis IV (Weissella viridescens)"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-RNO-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-SSC-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DRE-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SSC-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-BTA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DRE-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DME-209441" name="WG ligand not bound to FZ receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SSC-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-SPO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-CFA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-DRE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-CFA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DRE-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SPO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DRE-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="MetaCyc" id="PWY-7887" name="protein SAMPylation and SAMP-mediated thiolation"/>
            <pathway-xref db="Reactome" id="R-BTA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-CFA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DRE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-2564830" name="Cytosolic iron-sulfur cluster assembly"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-XTR-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-DDI-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-2644607" name="Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DRE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DRE-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-XTR-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-MMU-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DME-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DRE-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-MMU-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-GGA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DRE-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-DME-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DRE-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6462" name="peptidoglycan cross-bridge biosynthesis III (Enterococcus faecalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-DDI-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7832" name="ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-RNO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SCE-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-SCE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DDI-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DME-209421" name="Transcription activation by ARM"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-GGA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-DRE-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-CEL-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DME-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7546" name="diphthamide biosynthesis II (eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DRE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-DRE-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DME-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DRE-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SCE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-SCE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-CFA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-RNO-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-MMU-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-MMU-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-SPO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-DRE-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DME-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-DDI-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-BTA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-CFA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-CFA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DDI-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SCE-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-111463" name="SMAC (DIABLO) binds to IAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-CEL-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9687136" name="Aberrant regulation of mitotic exit in cancer due to RB1 defects"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-CFA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-RNO-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CEL-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-CFA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-9673766" name="Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-MMU-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DRE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-SCE-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-BTA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-DRE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DDI-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-HSA-194138" name="Signaling by VEGF"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-RNO-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DRE-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-SPO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-DDI-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SSC-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DDI-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-CFA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-111464" name="SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-SPO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-BTA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-CEL-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-GGA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DDI-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-BTA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CEL-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-CFA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-CEL-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-CEL-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DRE-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DDI-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5619107" name="Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CFA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-GGA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-CEL-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-CEL-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-SCE-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-BTA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DDI-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DME-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-DRE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-GGA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-DRE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CFA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-RNO-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-CEL-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-SCE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DDI-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DRE-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DRE-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-HSA-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-RNO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9710421" name="Defective pyroptosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-DDI-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SPO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SCE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-SCE-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-SCE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-CFA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DRE-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="Reactome" id="R-DDI-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CEL-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-DME-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DRE-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DME-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-GGA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-DME-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-HSA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-SCE-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-CFA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-HSA-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-180910" name="Vpr-mediated nuclear import of PICs"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-BTA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-GGA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SCE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-GGA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-XTR-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SSC-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-DME-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00320</model-ac>
        <locations>
          <hmmer2-location score="14.7" evalue="2.3" hmm-start="1" hmm-end="46" hmm-length="46" hmm-bounds="COMPLETE" start="1107" end="1150">
            <location-fragments>
              <hmmer2-location-fragment start="1107" end="1150" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="26.5" evalue="0.0037" hmm-start="1" hmm-end="46" hmm-length="46" hmm-bounds="COMPLETE" start="1244" end="1286">
            <location-fragments>
              <hmmer2-location-fragment start="1244" end="1286" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="12.8" evalue="4.6" hmm-start="1" hmm-end="46" hmm-length="46" hmm-bounds="COMPLETE" start="1203" end="1241">
            <location-fragments>
              <hmmer2-location-fragment start="1203" end="1241" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer3-match evalue="7.1E-10" score="39.2">
        <signature ac="PF01637" desc="ATPase domain predominantly from Archaea" name="ATPase_2">
          <entry ac="IPR011579" desc="ATPase domain" name="ATPase_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005524" name="ATP binding"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF01637</model-ac>
        <locations>
          <hmmer3-location env-end="608" env-start="475" post-processed="true" score="36.7" evalue="4.1E-9" hmm-start="2" hmm-end="47" hmm-length="233" hmm-bounds="INCOMPLETE" start="475" end="520">
            <location-fragments>
              <hmmer3-location-fragment start="475" end="520" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="6.4E-42" score="145.3">
        <signature ac="G3DSA:2.130.10.10" name="">
          <entry ac="IPR015943" desc="WD40/YVTN repeat-like-containing domain superfamily" name="WD40/YVTN_repeat-like_dom_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-HSA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-CEL-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-DRE-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-BTA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-DME-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-MMU-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CEL-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-SCE-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8293" name="alazopeptin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-MMU-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="MetaCyc" id="PWY-6967" name="methylamine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6841" name="homophytochelatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-1538133" name="G0 and Early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-5923" name="limonene degradation I (D-limonene)"/>
            <pathway-xref db="Reactome" id="R-DRE-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CEL-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-SCE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-CEL-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SPO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CEL-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-XTR-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-GGA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-6463" name="peptidoglycan cross-bridge biosynthesis IV (Weissella viridescens)"/>
            <pathway-xref db="MetaCyc" id="PWY-6926" name="pyrethrin I biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-SSC-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-BTA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-209441" name="WG ligand not bound to FZ receptors"/>
            <pathway-xref db="Reactome" id="R-SSC-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7887" name="protein SAMPylation and SAMP-mediated thiolation"/>
            <pathway-xref db="Reactome" id="R-DDI-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-XTR-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7779" name="methyl tert-butyl ether degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-HSA-202040" name="G-protein activation"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DRE-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-GGA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SCE-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-DDI-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SPO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SPO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SPO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-DRE-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-SCE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8033" name="aureothin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DME-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-7778" name="2-methylpropene degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SCE-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-CEL-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-735" name="jasmonic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6464" name="polyvinyl alcohol degradation"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-CFA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7536" name="2-amino-3-hydroxycyclopent-2-enone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-CEL-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9673766" name="Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-BTA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DRE-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-CFA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-111464" name="SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DDI-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-301" name="cyclohexane-1-carboxylate degradation (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DME-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-6457" name="cinnamoyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-CEL-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-BTA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-GGA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-427359" name="SIRT1 negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DRE-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-RNO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9710421" name="Defective pyroptosis"/>
            <pathway-xref db="Reactome" id="R-SPO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-DRE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7007" name="methyl ketone biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CFA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-RNO-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-180910" name="Vpr-mediated nuclear import of PICs"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-GGA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-RNO-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-DME-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CFA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DRE-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-BTA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SCE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-SPO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-CEL-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-GGA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-1362277" name="Transcription of E2F targets under negative control by DREAM complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-HSA-163359" name="Glucagon signaling in metabolic regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-SCE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-BTA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DRE-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-DME-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DRE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-168325" name="Viral Messenger RNA Synthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-BTA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-BTA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DRE-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DRE-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DDI-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-8034" name="spectinabilin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-BTA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DRE-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SPO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2644607" name="Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-XTR-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-6462" name="peptidoglycan cross-bridge biosynthesis III (Enterococcus faecalis)"/>
            <pathway-xref db="Reactome" id="R-RNO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7832" name="ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-RNO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SCE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DME-209421" name="Transcription activation by ARM"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-SSC-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DRE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8179" name="platensimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-DME-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DME-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-5693554" name="Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-CEL-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DDI-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-BTA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-5922" name="(4R)-carveol and (4R)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-111463" name="SMAC (DIABLO) binds to IAPs"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DRE-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CFA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7462" name="3,3'-disulfanediyldipropannoate degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-DME-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5136" name="fatty acid beta-oxidation II (plant peroxisome)"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="MetaCyc" id="PWY-6047" name="dimethyl sulfide degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-194138" name="Signaling by VEGF"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-RNO-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DME-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-CEL-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-GGA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-CFA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-MMU-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DDI-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-SSC-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-SCE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-DRE-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DRE-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-DDI-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DRE-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-SSC-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-GGA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-SPO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-390471" name="Association of TriC/CCT with target proteins during biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-SPO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-SCE-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="MetaCyc" id="PWY-5927" name="(4S)-carveol and (4S)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-RNO-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SPO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-6670" name="citronellol degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-CFA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DDI-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-BTA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-SSC-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DME-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-HSA-112314" name="Neurotransmitter receptors and postsynaptic signal transmission"/>
            <pathway-xref db="Reactome" id="R-DDI-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CEL-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-DME-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SPO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-BTA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-HSA-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-DME-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DRE-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-SSC-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DRE-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2564830" name="Cytosolic iron-sulfur cluster assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DDI-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-RNO-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DRE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-DDI-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6817" name="lambda-carrageenan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-DME-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DRE-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="MetaCyc" id="PWY-6812" name="xyloglucan degradation III (cellobiohydrolase)"/>
            <pathway-xref db="Reactome" id="R-MMU-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-SCE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-DRE-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-SPO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-DRE-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9687136" name="Aberrant regulation of mitotic exit in cancer due to RB1 defects"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-5958" name="acridone alkaloid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DRE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SPO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SSC-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-MMU-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DME-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DDI-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-GGA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-SCE-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DDI-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-GGA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DDI-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7084" name="nitrifier denitrification"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-DME-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DRE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-GGA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-6803207" name="TP53 Regulates Transcription of Caspase Activators and Caspases"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8004" name="Entner-Doudoroff pathway I"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7620" name="naphthalene degradation (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-SPO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="MetaCyc" id="PWY-8044" name="cyclohexane-1-carboxyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-DRE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7831" name="ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-MMU-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-CFA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-SSC-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DME-432620" name="Dephosphorylation of PER"/>
            <pathway-xref db="Reactome" id="R-GGA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-168271" name="Transport of Ribonucleoproteins into the Host Nucleus"/>
            <pathway-xref db="Reactome" id="R-SPO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-MMU-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="MetaCyc" id="PWY-6593" name="sulfoacetate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DME-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-SCE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-CFA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-GGA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-SSC-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-6289" name="petrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-CEL-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-MMU-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DRE-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CFA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-CFA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SPO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-CFA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="MetaCyc" id="PWY-6748" name="nitrate reduction VII (denitrification)"/>
            <pathway-xref db="Reactome" id="R-HSA-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-DRE-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DRE-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-GGA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="MetaCyc" id="PWY-7546" name="diphthamide biosynthesis II (eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-7288" name="fatty acid beta-oxidation VII (yeast peroxisome)"/>
            <pathway-xref db="Reactome" id="R-DRE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-GGA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-HSA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CFA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-CFA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CEL-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-HSA-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-RNO-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DDI-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DDI-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-SPO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-CEL-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-RNO-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-BTA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-CEL-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-SCE-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619107" name="Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CFA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-CEL-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-DRE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-HSA-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SCE-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-DME-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-5924" name="limonene degradation II (L-limonene)"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DME-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-SPO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-XTR-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SSC-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2ovrB02</model-ac>
        <locations>
          <hmmer3-location env-end="1218" env-start="992" post-processed="true" score="57.6" evalue="3.1E-15" hmm-start="30" hmm-end="212" hmm-length="340" hmm-bounds="N_TERMINAL_COMPLETE" start="992" end="1215">
            <location-fragments>
              <hmmer3-location-fragment start="992" end="1215" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="2.2E-26" score="94.8">
        <signature ac="G3DSA:2.130.10.10" name="">
          <entry ac="IPR015943" desc="WD40/YVTN repeat-like-containing domain superfamily" name="WD40/YVTN_repeat-like_dom_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-HSA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-CEL-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-DRE-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-BTA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-DME-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-MMU-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CEL-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-SCE-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8293" name="alazopeptin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-MMU-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="MetaCyc" id="PWY-6967" name="methylamine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6841" name="homophytochelatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-1538133" name="G0 and Early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-5923" name="limonene degradation I (D-limonene)"/>
            <pathway-xref db="Reactome" id="R-DRE-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CEL-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-SCE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-CEL-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SPO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CEL-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-XTR-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-GGA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-6463" name="peptidoglycan cross-bridge biosynthesis IV (Weissella viridescens)"/>
            <pathway-xref db="MetaCyc" id="PWY-6926" name="pyrethrin I biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-SSC-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-BTA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-209441" name="WG ligand not bound to FZ receptors"/>
            <pathway-xref db="Reactome" id="R-SSC-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7887" name="protein SAMPylation and SAMP-mediated thiolation"/>
            <pathway-xref db="Reactome" id="R-DDI-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-XTR-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7779" name="methyl tert-butyl ether degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-HSA-202040" name="G-protein activation"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DRE-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-GGA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SCE-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-DDI-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SPO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SPO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SPO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-DRE-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-SCE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8033" name="aureothin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DME-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-7778" name="2-methylpropene degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SCE-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-CEL-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-735" name="jasmonic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6464" name="polyvinyl alcohol degradation"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-CFA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7536" name="2-amino-3-hydroxycyclopent-2-enone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-CEL-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9673766" name="Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-BTA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DRE-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-CFA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-111464" name="SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DDI-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-301" name="cyclohexane-1-carboxylate degradation (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DME-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-6457" name="cinnamoyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-CEL-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-BTA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-GGA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-427359" name="SIRT1 negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DRE-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-RNO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9710421" name="Defective pyroptosis"/>
            <pathway-xref db="Reactome" id="R-SPO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-DRE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7007" name="methyl ketone biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CFA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-RNO-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-180910" name="Vpr-mediated nuclear import of PICs"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-GGA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-RNO-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-DME-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CFA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DRE-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-BTA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SCE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-SPO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-CEL-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-GGA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-1362277" name="Transcription of E2F targets under negative control by DREAM complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-HSA-163359" name="Glucagon signaling in metabolic regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-SCE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-BTA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DRE-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-DME-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DRE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-168325" name="Viral Messenger RNA Synthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-BTA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-BTA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DRE-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DRE-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DDI-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-8034" name="spectinabilin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-BTA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DRE-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SPO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2644607" name="Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-XTR-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-6462" name="peptidoglycan cross-bridge biosynthesis III (Enterococcus faecalis)"/>
            <pathway-xref db="Reactome" id="R-RNO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7832" name="ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-RNO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-SCE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-DME-209421" name="Transcription activation by ARM"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-SSC-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DRE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8179" name="platensimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-DME-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DME-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-5693554" name="Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-CEL-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DDI-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-BTA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-5922" name="(4R)-carveol and (4R)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-111463" name="SMAC (DIABLO) binds to IAPs"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DRE-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CFA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7462" name="3,3'-disulfanediyldipropannoate degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-DME-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5136" name="fatty acid beta-oxidation II (plant peroxisome)"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="MetaCyc" id="PWY-6047" name="dimethyl sulfide degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-194138" name="Signaling by VEGF"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-RNO-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DME-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-CEL-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-GGA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-CFA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-MMU-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DDI-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-SSC-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-SCE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-DRE-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DRE-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-DDI-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DRE-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-SSC-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-GGA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-SPO-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-390471" name="Association of TriC/CCT with target proteins during biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-SPO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-SCE-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-HSA-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="MetaCyc" id="PWY-5927" name="(4S)-carveol and (4S)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-RNO-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SPO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-6670" name="citronellol degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-CFA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DDI-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-BTA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-SSC-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DME-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-HSA-112314" name="Neurotransmitter receptors and postsynaptic signal transmission"/>
            <pathway-xref db="Reactome" id="R-DDI-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CEL-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-DME-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SPO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-BTA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-HSA-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-DME-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DRE-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-SSC-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DRE-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2564830" name="Cytosolic iron-sulfur cluster assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DDI-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-RNO-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DRE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-DDI-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-SPO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6817" name="lambda-carrageenan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-DME-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DRE-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="MetaCyc" id="PWY-6812" name="xyloglucan degradation III (cellobiohydrolase)"/>
            <pathway-xref db="Reactome" id="R-MMU-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-SCE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-DRE-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-SPO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-DRE-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9687136" name="Aberrant regulation of mitotic exit in cancer due to RB1 defects"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-5958" name="acridone alkaloid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DRE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SPO-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SSC-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-MMU-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-CEL-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DME-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DDI-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-GGA-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-SCE-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DDI-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-GGA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DDI-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7084" name="nitrifier denitrification"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-DME-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-SPO-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DRE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DDI-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-GGA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-6803207" name="TP53 Regulates Transcription of Caspase Activators and Caspases"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8004" name="Entner-Doudoroff pathway I"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7620" name="naphthalene degradation (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-SPO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="MetaCyc" id="PWY-8044" name="cyclohexane-1-carboxyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-DRE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7831" name="ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-MMU-1296041" name="Activation of G protein gated Potassium channels"/>
            <pathway-xref db="Reactome" id="R-CFA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-SSC-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DME-432620" name="Dephosphorylation of PER"/>
            <pathway-xref db="Reactome" id="R-GGA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-168271" name="Transport of Ribonucleoproteins into the Host Nucleus"/>
            <pathway-xref db="Reactome" id="R-SPO-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-MMU-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="MetaCyc" id="PWY-6593" name="sulfoacetate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DME-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-SCE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-CFA-418217" name="G beta:gamma signalling through PLC beta"/>
            <pathway-xref db="Reactome" id="R-GGA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-SSC-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-6289" name="petrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-CEL-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-MMU-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DRE-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CFA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-CFA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SPO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-CFA-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="MetaCyc" id="PWY-6748" name="nitrate reduction VII (denitrification)"/>
            <pathway-xref db="Reactome" id="R-HSA-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-DRE-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DRE-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-GGA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="MetaCyc" id="PWY-7546" name="diphthamide biosynthesis II (eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="MetaCyc" id="PWY-7288" name="fatty acid beta-oxidation VII (yeast peroxisome)"/>
            <pathway-xref db="Reactome" id="R-DRE-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-GGA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-HSA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CFA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-CFA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CEL-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-HSA-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-RNO-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-176407" name="Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DRE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DDI-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DDI-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-SPO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-CEL-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-RNO-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-BTA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-MMU-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-CEL-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-SCE-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-997272" name="Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619107" name="Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CFA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-CEL-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-DRE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-HSA-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DME-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SCE-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-DME-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-5924" name="limonene degradation II (L-limonene)"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-4641265" name="Repression of WNT target genes"/>
            <pathway-xref db="Reactome" id="R-DME-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DRE-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-500657" name="Presynaptic function of Kainate receptors"/>
            <pathway-xref db="Reactome" id="R-SPO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-XTR-212300" name="PRC2 methylates histones and DNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SSC-176409" name="APC/C:Cdc20 mediated degradation of mitotic proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>4u1eI00</model-ac>
        <locations>
          <hmmer3-location env-end="1344" env-start="1213" post-processed="true" score="65.0" evalue="2.5E-17" hmm-start="15" hmm-end="113" hmm-length="347" hmm-bounds="C_TERMINAL_COMPLETE" start="1216" end="1344">
            <location-fragments>
              <hmmer3-location-fragment start="1216" end="1344" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="8.5E-15" score="56.7">
        <signature ac="G3DSA:3.40.50.300" name="">
          <entry ac="IPR027417" desc="P-loop containing nucleoside triphosphate hydrolase" name="P-loop_NTPase" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="MetaCyc" id="PWY-8238" name="24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-SCE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SSC-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-HSA-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6973" name="dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SCE-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7177" name="UTP and CTP dephosphorylation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7631" name="arctigenin and isoarctigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-DME-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DDI-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9684325" name="Maturation of replicase proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-BTA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-DME-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SPO-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9617324" name="Negative regulation of NMDA receptor-mediated neuronal transmission"/>
            <pathway-xref db="MetaCyc" id="PWY-2821" name="glucosinolate biosynthesis from phenylalanine"/>
            <pathway-xref db="Reactome" id="R-SSC-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-3961" name="phosphopantothenate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-RNO-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6526" name="limonene degradation III (to perillate)"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-DRE-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8283" name="lipid IVA biosynthesis (generic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7591" name="okenone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CEL-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-CEL-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DDI-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-HSA-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DDI-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DDI-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DME-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CEL-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-GGA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-XTR-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DME-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-PFA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-BTA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-SPO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SCE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-MMU-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-5070" name="gibberellin biosynthesis I (non C-3, non C-13 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-PFA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6932" name="selenate reduction"/>
            <pathway-xref db="Reactome" id="R-RNO-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-SPO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9636569" name="Suppression of autophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-SSC-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DRE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2161541" name="Abacavir metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-5047" name="gibberellin biosynthesis IV (Gibberella fujikuroi)"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SCE-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DDI-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-SSC-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DDI-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-PFA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-GGA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7219" name="adenosine ribonucleotides de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-GGA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-CEL-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-PFA-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DDI-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-HSA-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CFA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SSC-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-GGA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-DRE-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-8106" name="queuosine biosynthesis III (queuosine salvage)"/>
            <pathway-xref db="Reactome" id="R-GGA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-SCE-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-DME-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CEL-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SSC-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SSC-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="MetaCyc" id="PWY-7752" name="gadusol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-BTA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SCE-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-DDI-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-PFA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-MMU-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-CFA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-RNO-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SCE-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SPO-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-RNO-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-3371511" name="HSF1 activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7498" name="phenylpropanoids methylation (ice plant)"/>
            <pathway-xref db="Reactome" id="R-HSA-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-DRE-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5729" name="vestitol and sativan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-SPO-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-BTA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-HSA-5632928" name="Defective Mismatch Repair Associated With MSH2"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8148" name="NADP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DME-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CFA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-GGA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CEL-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-RNO-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7977" name="L-methionine biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-SPO-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-GGA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-BTA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-SCE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7363" name="papaverine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-HSA-5649702" name="APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8076" name="8-O-methylated benzoxazinoid glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-GGA-171007" name="p38MAPK events"/>
            <pathway-xref db="MetaCyc" id="PWY-7534" name="gliotoxin inactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CFA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DRE-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-CEL-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7643" name="coniferyl alcohol 9-methyl ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SSC-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-CEL-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8943723" name="Regulation of PTEN mRNA translation"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-DDI-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DRE-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-DME-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7379" name="mRNA capping II"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="MetaCyc" id="PWY-4021" name="beta-alanine betaine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7391" name="isoprene biosynthesis II (engineered)"/>
            <pathway-xref db="Reactome" id="R-DME-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-6383" name="mono-trans, poly-cis decaprenyl phosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-SSC-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SPO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DDI-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-PFA-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="MetaCyc" id="PWY-5530" name="sorbitol biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-HSA-2408550" name="Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-MMU-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-SCE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6281" name="L-selenocysteine biosynthesis II (archaea and eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DRE-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-CFA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CFA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-DDI-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-CFA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="MetaCyc" id="PWY-6998" name="CDP-D-arabitol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="MetaCyc" id="PWY-8260" name="roxarsone degradation I"/>
            <pathway-xref db="Reactome" id="R-DME-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-DDI-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9694786" name="Transcription of SARS-CoV-2 sgRNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CFA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-351451" name="Homologous recombination repair of replication-dependent double-strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DRE-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-351433" name="ATM mediated phosphorylation of repair proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-MMU-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-7301" name="dTDP-4-O-demethyl-beta-L-noviose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7220" name="adenosine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SCE-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DRE-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DDI-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-922" name="mevalonate pathway I (eukaryotes and bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-350407" name="RHO1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2201" name="folate transformations I"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7377" name="cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)"/>
            <pathway-xref db="MetaCyc" id="PWY-6581" name="spirilloxanthin and 2,2'-diketo-spirilloxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5684045" name="Defective ABCD1 causes ALD"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6795" name="diacylglyceryl-N,N,N-trimethylhomoserine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7248" name="pectin degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-MMU-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DDI-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-GGA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-DME-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6086" name="4-chloro-2-methylphenoxyacetate degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-69091" name="Polymerase switching"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6421" name="arsenate detoxification IV (mycothiol)"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6707" name="gallate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-SCE-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-XTR-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5748" name="gamma-coniciene and coniine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-BTA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8171" name="molybdenum cofactor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-7691" name="10,13-epoxy-11-methyl-octadecadienoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DRE-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5209" name="methyl-coenzyme M oxidation to CO2"/>
            <pathway-xref db="Reactome" id="R-CFA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-DDI-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-HSA-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7904" name="tRNA-uridine 2-thiolation (thermophilic bacteria)"/>
            <pathway-xref db="Reactome" id="R-CEL-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SCE-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DRE-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="Reactome" id="R-RNO-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-RNO-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-CEL-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-1222387" name="Tolerance of reactive oxygen produced by macrophages"/>
            <pathway-xref db="MetaCyc" id="PWY-7250" name="[2Fe-2S] iron-sulfur cluster biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-CFA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-111464" name="SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-SCE-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7205" name="CMP phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-CFA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5287" name="sanguinarine and macarpine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DDI-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-SCE-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-SCE-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DDI-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-CEL-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-7972" name="adenosylcobinamide-GDP salvage from cobinamide II"/>
            <pathway-xref db="MetaCyc" id="PWY-5109" name="propanoate fermentation to 2-methylbutanoate"/>
            <pathway-xref db="Reactome" id="R-DME-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DDI-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-BTA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-XTR-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7227" name="adenosine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SSC-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7183" name="pyrimidine nucleobases salvage I"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-1281" name="sulfoacetaldehyde degradation I"/>
            <pathway-xref db="Reactome" id="R-CEL-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683678" name="Defective ABCA3 causes SMDP3"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-DDI-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-CEL-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7298" name="nevadensin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-CFA-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-SPO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DDI-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-DME-216167" name="Nuclear CI is degraded"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SPO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-GGA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-RNO-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-HSA-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-GGA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7226" name="guanosine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-CEL-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-BTA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DRE-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6797" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus)"/>
            <pathway-xref db="Reactome" id="R-DME-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-DRE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-SCE-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-DDI-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-DRE-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="MetaCyc" id="PWY-7962" name="adenosylcobinamide-GDP biosynthesis from cobyrinate a,c-diamide"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DDI-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-CFA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-DRE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1912420" name="Pre-NOTCH Processing in Golgi"/>
            <pathway-xref db="Reactome" id="R-HSA-8948700" name="Competing endogenous RNAs (ceRNAs) regulate PTEN translation"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="MetaCyc" id="PWY-8031" name="epiberberine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-PFA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-GGA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7007" name="methyl ketone biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-CEL-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5497" name="purine nucleobases degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-CFA-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CFA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-BTA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7742" name="phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-SCE-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SCE-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-DME-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-SPO-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SPO-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-SPO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-4161" name="superpathway of benzoxazinoid glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6398" name="melatonin degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SSC-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-HSA-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-7274" name="D-cycloserine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-6339" name="syringate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8073" name="lipid IVA biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-SCE-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-DME-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-GGA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DDI-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-HSA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-8934593" name="Regulation of RUNX1 Expression and Activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5301" name="ajmaline and sarpagine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DRE-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-RNO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-6802953" name="RAS signaling downstream of NF1 loss-of-function variants"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-GGA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-CFA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="MetaCyc" id="PWY-5083" name="NAD(P)/NADPH interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-DDI-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SCE-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SCE-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DME-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7163" name="polymethylated kaempferol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-SCE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-SCE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-BTA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-SSC-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-HSA-5682294" name="Defective ABCA12 causes ARCI4B"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-CEL-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-GGA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-CEL-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-BTA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-RNO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-CEL-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6502" name="8-oxo-(d)GTP detoxification I"/>
            <pathway-xref db="Reactome" id="R-SPO-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-DDI-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-GGA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="MetaCyc" id="PWY-6545" name="pyrimidine deoxyribonucleotides de novo biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1362277" name="Transcription of E2F targets under negative control by DREAM complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-SSC-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-5773" name="gossypol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5690338" name="Defective ABCC6 causes PXE"/>
            <pathway-xref db="Reactome" id="R-GGA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-BTA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6154" name="autoinducer AI-2 biosynthesis II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-DDI-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-CEL-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-8245" name="lipid IVA biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-163359" name="Glucagon signaling in metabolic regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-PFA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-421203" name="De novo synthesis of AMP"/>
            <pathway-xref db="Reactome" id="R-HSA-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="MetaCyc" id="PWY-6369" name="inositol diphosphates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-PFA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="MetaCyc" id="PWY-7905" name="Escherichia coli serotype O:9a O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-167160" name="RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-CEL-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-SSC-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5362768" name="Hh mutants are degraded by ERAD"/>
            <pathway-xref db="MetaCyc" id="PWY-7741" name="phthiocerol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SSC-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-SPO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CFA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688399" name="Defective ABCA3 causes SMDP3"/>
            <pathway-xref db="Reactome" id="R-HSA-9613829" name="Chaperone Mediated Autophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CFA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-XTR-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-XTR-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-GGA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DME-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-DRE-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8104" name="yangonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-RNO-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-BTA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-DDI-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-CEL-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-HSA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-CFA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-DRE-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-RNO-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-BTA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-SCE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-PFA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-RNO-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-BTA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8138" name="polyphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-SCE-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-3841" name="folate transformations II (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7185" name="UTP and CTP dephosphorylation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-HSA-1221632" name="Meiotic synapsis"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-RNO-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-DME-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-DRE-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-DRE-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-GGA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5679096" name="Defective ABCG5 causes sitosterolemia"/>
            <pathway-xref db="Reactome" id="R-SCE-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-GGA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-DME-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5059" name="pinobanksin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6835" name="6-gingerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-SSC-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-BTA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-981" name="salicylate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SSC-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DME-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-CEL-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="MetaCyc" id="PWY-6917" name="vernolate biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-DDI-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-PFA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-CEL-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-6519" name="8-amino-7-oxononanoate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CFA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8289" name="dZTP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-DDI-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-MMU-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-CEL-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-SCE-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-SCE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-538864" name="Degradation of CRY"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-DRE-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-GGA-265976" name="Homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8986944" name="Transcriptional Regulation by MECP2"/>
            <pathway-xref db="Reactome" id="R-DDI-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-SPO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DDI-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7181" name="pyrimidine deoxyribonucleosides degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-351465" name="Fanconi Anemia Pathway in DNA repair"/>
            <pathway-xref db="Reactome" id="R-CFA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6477" name="gibberellin inactivation II (methylation)"/>
            <pathway-xref db="Reactome" id="R-DDI-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-MMU-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-CFA-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-DDI-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DRE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-MMU-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-CFA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-CEL-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7980" name="ATP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5679001" name="Defective ABCC2 causes DJS"/>
            <pathway-xref db="Reactome" id="R-DME-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-DME-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="MetaCyc" id="PWY-6978" name="plastoquinol-9 biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-GGA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-GGA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-RNO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DRE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-DRE-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-RNO-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SPO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7901" name="glucosinolate biosynthesis from tyrosine"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-5632927" name="Defective Mismatch Repair Associated With MSH3"/>
            <pathway-xref db="Reactome" id="R-PFA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-7975" name="adenosylcobalamin biosynthesis from adenosylcobinamide-GDP II"/>
            <pathway-xref db="Reactome" id="R-DRE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9670615" name="Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"/>
            <pathway-xref db="MetaCyc" id="PWY-8179" name="platensimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7524" name="mevalonate pathway III (Thermoplasma)"/>
            <pathway-xref db="Reactome" id="R-DME-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-DME-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-CFA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SSC-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SSC-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-SSC-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SCE-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-5693554" name="Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"/>
            <pathway-xref db="MetaCyc" id="PWY-7483" name="elloramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-DRE-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7564" name="bacimethrin and bacimethrin pyrophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-BTA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-GGA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-SPO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DRE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DDI-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-SPO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-HSA-9662834" name="CD163 mediating an anti-inflammatory response"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6981" name="chitin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-111463" name="SMAC (DIABLO) binds to IAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DRE-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-RNO-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DDI-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-SCE-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SPO-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6689" name="tRNA splicing I"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-DME-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7292" name="oleate beta-oxidation (thioesterase-dependent, yeast)"/>
            <pathway-xref db="Reactome" id="R-RNO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SSC-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CFA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-9635465" name="Suppression of apoptosis"/>
            <pathway-xref db="Reactome" id="R-HSA-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SCE-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-SSC-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DDI-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-SCE-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-SSC-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-BTA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2083" name="isoflavonoid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SCE-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DRE-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="MetaCyc" id="PWY-8264" name="arsenate detoxification I"/>
            <pathway-xref db="Reactome" id="R-DME-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-DDI-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7224" name="purine deoxyribonucleosides salvage"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DRE-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-5928" name="(4R)-carvone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-SSC-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-SSC-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7104" name="dTDP-beta-L-megosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-CEL-156902" name="Peptide chain elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-HSA-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-MMU-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-GGA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-BTA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-MMU-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-6427" name="rot-2'-enonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7931" name="brominated pyrroles biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8117" name="colibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-HSA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-SCE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DME-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-HSA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SSC-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-GGA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-6683" name="assimilatory sulfate reduction III"/>
            <pathway-xref db="Reactome" id="R-CEL-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DME-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-GGA-352882" name="Glycolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-PFA-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-162588" name="Budding and maturation of HIV virion"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-BTA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DRE-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-GGA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="Reactome" id="R-CFA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SCE-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-XTR-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8083" name="domoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-BTA-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-SSC-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7127" name="CDP-D-mannitol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7805" name="(aminomethyl)phosphonate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-6409" name="pyoverdine I biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DRE-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5665" name="vanillin biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-SCE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-5723" name="Rubisco shunt"/>
            <pathway-xref db="Reactome" id="R-SSC-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-CFA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-SSC-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SCE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-5678895" name="Defective CFTR causes cystic fibrosis"/>
            <pathway-xref db="Reactome" id="R-SPO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-CEL-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-DME-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-5683177" name="Defective ABCC8 can cause hypo- and hyper-glycemias"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-DDI-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-CEL-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="MetaCyc" id="PWY-7539" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)"/>
            <pathway-xref db="Reactome" id="R-HSA-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-7380" name="biotin biosynthesis from 8-amino-7-oxononanoate II"/>
            <pathway-xref db="Reactome" id="R-CFA-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9674519" name="Defective F8 sulfation at Y1699"/>
            <pathway-xref db="MetaCyc" id="PWY-8015" name="glycine degradation (reductive Stickland reaction)"/>
            <pathway-xref db="Reactome" id="R-DME-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-983189" name="Kinesins"/>
            <pathway-xref db="MetaCyc" id="PWY-4061" name="glutathione-mediated detoxification I"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-DME-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-601" name="glucosinolate biosynthesis from tryptophan"/>
            <pathway-xref db="Reactome" id="R-SSC-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-CEL-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-5340" name="sulfate activation for sulfonation"/>
            <pathway-xref db="Reactome" id="R-SCE-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="MetaCyc" id="PWY-7159" name="3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7199" name="pyrimidine deoxyribonucleosides salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-3359475" name="Defective MMAA causes methylmalonic aciduria type cblA"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-SPO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-8172" name="10-methylstearate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5757" name="fosfomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-CFA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SPO-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-CEL-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8080" name="kainate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DRE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-SPO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-SPO-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7704" name="viridicatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SCE-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-112126" name="ALKBH3 mediated reversal of alkylation damage"/>
            <pathway-xref db="Reactome" id="R-CEL-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-DDI-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DME-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-7325" name="salvigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-72203" name="Processing of Capped Intron-Containing Pre-mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="MetaCyc" id="PWY-7629" name="yatein biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-GGA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-DME-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-RNO-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-CEL-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-933541" name="TRAF6 mediated IRF7 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-SSC-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SPO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-390471" name="Association of TriC/CCT with target proteins during biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-SPO-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-BTA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CFA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-7268" name="cytosolic NADPH production (yeast)"/>
            <pathway-xref db="Reactome" id="R-CFA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-CFA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SSC-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-HSA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-7840" name="gala-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-7184" name="pyrimidine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7886" name="cell-surface glycoconjugate-linked phosphocholine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6286" name="spheroidene and spheroidenone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7668" name="apicidin F biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-7197" name="pyrimidine deoxyribonucleotide phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SPO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-SPO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DRE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-MMU-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-DDI-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-DME-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="MetaCyc" id="PWY-5443" name="aminopropanol phosphate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-209159" name="Assembly of the CI containing complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-SSC-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7667" name="apicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-7398" name="coumarins biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7734" name="quinoxaline-2-carboxylate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-BTA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7285" name="methylwyosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-DME-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-BTA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SPO-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-HSA-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3560796" name="Defective PAPSS2 causes SEMD-PA"/>
            <pathway-xref db="Reactome" id="R-SCE-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-HSA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DRE-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5368286" name="Mitochondrial translation initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-72203" name="Processing of Capped Intron-Containing Pre-mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="MetaCyc" id="PWY-7210" name="pyrimidine deoxyribonucleotides biosynthesis from CTP"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-1187" name="glucosinolate biosynthesis from homomethionine"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-RNO-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-4202" name="arsenic detoxification (mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-7851" name="coenzyme A biosynthesis II (eukaryotic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DME-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-SSC-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DME-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2408557" name="Selenocysteine synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DRE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-CEL-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-7705" name="4'-methoxyviridicatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DRE-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-167158" name="Formation of the HIV-1 Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-PFA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-HSA-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6416" name="quinate degradation II"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6637" name="sulfolactate degradation II"/>
            <pathway-xref db="Reactome" id="R-CEL-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-GGA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7717" name="3-hydroxy-4-methyl-anthranilate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7376" name="cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation)"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-8949613" name="Cristae formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7655" name="dechlorogriseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7607" name="meleagrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6585" name="2-methylketone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8101" name="arsenate detoxification II"/>
            <pathway-xref db="Reactome" id="R-SCE-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DRE-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7765" name="3-hydroxy-4-methyl-anthranilate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-GGA-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-GGA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-7155" name="7-dehydroporiferasterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-912446" name="Meiotic recombination"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5336415" name="Uptake and function of diphtheria toxin"/>
            <pathway-xref db="Reactome" id="R-SSC-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-CEL-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5649702" name="APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-GGA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2564830" name="Cytosolic iron-sulfur cluster assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4621" name="arsenic detoxification (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-RNO-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-MMU-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-SCE-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7193" name="pyrimidine ribonucleosides salvage I"/>
            <pathway-xref db="Reactome" id="R-DME-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-RNO-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-DDI-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6919" name="neopentalenoketolactone and pentalenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-SCE-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7439" name="dTDP-beta-L-evernitrose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-BTA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SSC-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-DME-432626" name="Circadian Clock pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="Reactome" id="R-SSC-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-9708296" name="tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="MetaCyc" id="PWY-5531" name="3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-CFA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-GGA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-HSA-1222449" name="Mtb iron assimilation by chelation"/>
            <pathway-xref db="Reactome" id="R-RNO-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="MetaCyc" id="PWY-7187" name="pyrimidine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-GGA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7649" name="3-hydroxy-L-homotyrosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DME-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DME-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-RNO-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-SPO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8129" name="cell-surface glycoconjugate-linked phosphonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-DME-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7440" name="dTDP-beta-L-4-epi-vancosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-DME-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-SCE-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-SCE-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8167" name="bis(tungstenpterin) cofactor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DME-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5621480" name="Dectin-2 family"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7608" name="neoxaline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6085" name="2,4-dichlorophenoxyacetate degradation"/>
            <pathway-xref db="Reactome" id="R-XTR-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DME-110523" name="TOR signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-GGA-217106" name="Chk1-controlled and DNA-damage induced centrosome duplication"/>
            <pathway-xref db="MetaCyc" id="PWY-7221" name="guanosine ribonucleotides de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DDI-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-SSC-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8095" name="5-methoxy-6-methylbenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MTU-936635" name="Sulfate assimilation"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-SPO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-2681" name="trans-zeatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DRE-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-GGA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7648" name="3-hydroxy-4-methyl-proline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-DME-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7402" name="benzoate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="Reactome" id="R-DRE-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-5526" name="bacteriochlorophyll a biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8184" name="L-isoleucine degradation III (oxidative Stickland reaction)"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7176" name="UTP and CTP de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4983" name="nitric oxide biosynthesis II (mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-CFA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-CEL-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8096" name="5-methoxybenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-SCE-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-SSC-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5678771" name="Defective ABCB4 causes PFIC3, ICP3 and GBD1"/>
            <pathway-xref db="Reactome" id="R-SPO-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DDI-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-MMU-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DRE-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DDI-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-BTA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-GGA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DME-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-BTA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-CEL-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5305" name="bixin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-DME-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DRE-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-8876725" name="Protein methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7614" name="methiin metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-918233" name="TRAF3-dependent IRF activation pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SPO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-CEL-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SCE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7826" name="Amaryllidacea alkaloids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-BTA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SCE-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5278" name="sulfite oxidation III"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-BTA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6995" name="5-hydroxymethylfurfural degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-SSC-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-HSA-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SPO-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-XTR-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-GGA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SCE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DRE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-5035" name="gibberellin biosynthesis III (early C-13 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-SPO-8876725" name="Protein methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7733" name="3-hydroxyquinaldate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-GGA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-SPO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-CFA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-SSC-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-SCE-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-6997" name="furfural degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5683371" name="Defective ABCB6 causes MCOPCB7"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-SCE-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CFA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9694271" name="Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)"/>
            <pathway-xref db="Reactome" id="R-DME-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-DME-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-CFA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-GGA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8303" name="reductive glycine pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-SPO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DME-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="MetaCyc" id="PWY-7789" name="erythritol degradation I"/>
            <pathway-xref db="Reactome" id="R-GGA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-181" name="photorespiration"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-BTA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9649913" name="RAS GTPase cycle mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-RNO-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7948" name="4-oxopentanoate degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-CEL-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6626" name="cytidine-5'-diphosphate-glycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-RNO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-SPO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-GGA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DRE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1222538" name="Tolerance by Mtb to nitric oxide produced by macrophages"/>
            <pathway-xref db="Reactome" id="R-SCE-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5632968" name="Defective Mismatch Repair Associated With MSH6"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-MMU-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="MetaCyc" id="PWY-6613" name="tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"/>
            <pathway-xref db="Reactome" id="R-MMU-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7751" name="shinorine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-MMU-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-MMU-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-RNO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-CFA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5683329" name="Defective ABCD4 causes MAHCJ"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-MMU-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-SSC-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-983712" name="Ion channel transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-CEL-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-CEL-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-XTR-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-DME-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6976" name="dTDP-beta-L-mycarose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="MetaCyc" id="PWY-7342" name="superpathway of nicotine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-6163" name="chorismate biosynthesis from 3-dehydroquinate"/>
            <pathway-xref db="Reactome" id="R-RNO-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DDI-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-DRE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DME-216119" name="Activation of CI"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-DRE-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-DME-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5765" name="1,3,5-trimethoxybenzene biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-DME-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-SSC-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-SPO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3359478" name="Defective MUT causes methylmalonic aciduria mut type"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-6313" name="serotonin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-GGA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-RNO-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-DDI-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SSC-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-SSC-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DRE-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-389977" name="Post-chaperonin tubulin folding pathway"/>
            <pathway-xref db="Reactome" id="R-DME-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5678520" name="Defective ABCB11 causes PFIC2 and BRIC2"/>
            <pathway-xref db="Reactome" id="R-SCE-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-113507" name="E2F-enabled inhibition of pre-replication complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DME-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-SCE-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-DME-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-SSC-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-6567" name="chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-6199" name="quercetin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-GGA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-SCE-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9694614" name="Attachment and Entry"/>
            <pathway-xref db="Reactome" id="R-HSA-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-DRE-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7076" name="3,5-dimethoxytoluene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-SPO-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-CFA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-5107" name="phytol salvage pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-DME-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-SPO-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-180585" name="Vif-mediated degradation of APOBEC3G"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-9678110" name="Attachment and Entry"/>
            <pathway-xref db="Reactome" id="R-DME-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-SCE-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DRE-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-HSA-844623" name="The IPAF inflammasome"/>
            <pathway-xref db="Reactome" id="R-HSA-6803207" name="TP53 Regulates Transcription of Caspase Activators and Caspases"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-RNO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8100" name="crotonosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7888" name="tRNA-uridine 2-thiolation (cytoplasmic)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-163767" name="PP2A-mediated dephosphorylation of key metabolic factors"/>
            <pathway-xref db="Reactome" id="R-SCE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-SCE-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-DRE-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DME-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1606341" name="IRF3 mediated activation of type 1 IFN"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-SSC-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5883" name="ephedrine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DME-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5682113" name="Defective ABCA1 causes TGD"/>
            <pathway-xref db="Reactome" id="R-DME-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-HSA-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-7831" name="ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-RNO-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CFA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-GGA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-GGA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-RNO-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5349" name="esculetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7232" name="gibberellin biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-CEL-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-BTA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DRE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-CEL-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-HSA-5601884" name="PIWI-interacting RNA (piRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SSC-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-SCE-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-6739" name="pinitol biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-DME-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-9682708" name="Transcription of SARS-CoV-1 sgRNAs"/>
            <pathway-xref db="MetaCyc" id="PWY-5479" name="6-methoxypodophyllotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-HSA-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DME-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-SPO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-6164" name="3-dehydroquinate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DDI-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="MetaCyc" id="PWY-7077" name="N-acetyl-D-galactosamine degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DRE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6269" name="superpathway of adenosylcobalamin salvage from cobinamide II"/>
            <pathway-xref db="Reactome" id="R-MMU-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DDI-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-RNO-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-DDI-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-GGA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-BTA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-DDI-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DME-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-MMU-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-DDI-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-RNO-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DDI-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-HSA-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-CEL-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1061" name="homogalacturonan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="Reactome" id="R-SPO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9694301" name="Maturation of replicase proteins"/>
            <pathway-xref db="Reactome" id="R-PFA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7909" name="formaldehyde oxidation VII (THF pathway)"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5485" name="pyruvate fermentation to acetate IV"/>
            <pathway-xref db="Reactome" id="R-MMU-983712" name="Ion channel transport"/>
            <pathway-xref db="MetaCyc" id="PWY-2781" name="cis-zeatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5678420" name="Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-MMU-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-SCE-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DDI-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-DDI-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7031" name="protein N-glycosylation (bacterial)"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6915" name="pentalenolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-SCE-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-9615710" name="Late endosomal microautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-XTR-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-DME-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="MetaCyc" id="PWY-6436" name="perillyl aldehyde biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-XTR-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7533" name="gliotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-GGA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-2453864" name="Retinoid cycle disease events"/>
            <pathway-xref db="Reactome" id="R-RNO-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="Reactome" id="R-BTA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-DME-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-CEL-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SSC-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6261" name="thyroid hormone metabolism II (via conjugation and/or degradation)"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="MetaCyc" id="PWY-7739" name="aucuparin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-164944" name="Nef and signal transduction"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DRE-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6787450" name="tRNA modification in the mitochondrion"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-SCE-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-DDI-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-SPO-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SPO-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-HSA-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-RNO-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-DRE-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-163358" name="PKA-mediated phosphorylation of key metabolic factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DDI-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SCE-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-RNO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-MMU-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-GGA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7079" name="geodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CEL-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-350480" name="Activation of non-muscle Myosin II"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-SPO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-933543" name="NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"/>
            <pathway-xref db="Reactome" id="R-GGA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-DDI-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-MMU-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-DDI-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-HSA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DRE-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7971" name="adenosylcobinamide-GDP salvage from cobinamide I"/>
            <pathway-xref db="Reactome" id="R-RNO-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-CFA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6568" name="dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-SCE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-5030" name="L-histidine degradation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DDI-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-432395" name="Degradation of TIM"/>
            <pathway-xref db="Reactome" id="R-HSA-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SPO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-352875" name="Gluconeogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-XTR-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-DME-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-DME-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-RNO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-CEL-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-DDI-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-CEL-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-DDI-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6045" name="methylthiopropanonate degradation II (demethylation)"/>
            <pathway-xref db="Reactome" id="R-DRE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8077" name="ginkgotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-SPO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DME-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8103" name="kavain biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-SPO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-GGA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CFA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="MetaCyc" id="PWY-5316" name="nicotine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SSC-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SCE-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DME-216217" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6153" name="autoinducer AI-2 biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DME-350368" name="Activation of RHO1 by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-DME-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-2161517" name="Abacavir transmembrane transport"/>
            <pathway-xref db="Reactome" id="R-RNO-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-3542" name="choline biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-HSA-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-SPO-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-SPO-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7161" name="polymethylated quercetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CEL-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-MMU-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-MMU-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-9694686" name="Replication of the SARS-CoV-2 genome"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-SCE-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-GGA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7729" name="5,6-dimethylbenzimidazole biosynthesis II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-GGA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DME-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-GGA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DDI-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-HSA-8935964" name="RUNX1 regulates expression of components of tight junctions"/>
            <pathway-xref db="MetaCyc" id="PWY-2161" name="folate polyglutamylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7485" name="tetracenomycin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-8086" name="(S)-lactate fermentation to propanoate, acetate and hydrogen"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7222" name="guanosine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CEL-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8964058" name="HDL remodeling"/>
            <pathway-xref db="Reactome" id="R-RNO-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-MMU-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-9670613" name="Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-GGA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-DDI-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-GGA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-SCE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SCE-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SCE-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-HSA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-SSC-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9682706" name="Replication of the SARS-CoV-1 genome"/>
            <pathway-xref db="Reactome" id="R-CFA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-176974" name="Unwinding of DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-SPO-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6736" name="sulfur volatiles biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-DRE-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7269" name="mitochondrial NADPH production (yeast)"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DME-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-CFA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-9683439" name="Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)"/>
            <pathway-xref db="Reactome" id="R-MMU-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-MMU-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="Reactome" id="R-MMU-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SSC-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DRE-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-SPO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-CFA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-DME-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-MMU-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DME-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MTU-964903" name="Chorismate via Shikimate Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-SSC-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DME-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="Reactome" id="R-SPO-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5482" name="pyruvate fermentation to acetate II"/>
            <pathway-xref db="Reactome" id="R-DRE-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-GGA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-SCE-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-7160" name="polymethylated myricetin biosynthesis (tomato)"/>
            <pathway-xref db="MetaCyc" id="PWY-102" name="gibberellin inactivation I (2beta-hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-CEL-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DRE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="MetaCyc" id="PWY-5036" name="gibberellin biosynthesis II (early C-3 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-CFA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8098" name="cyclic 2,3-bisphosphoglycerate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-HSA-9633012" name="Response of EIF2AK4 (GCN2) to amino acid deficiency"/>
            <pathway-xref db="Reactome" id="R-MMU-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SPO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-CEL-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-CEL-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-SPO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SPO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5679090" name="Defective ABCG8 causes GBD4 and sitosterolemia"/>
            <pathway-xref db="Reactome" id="R-BTA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-HSA-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CFA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-SCE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DME-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-SCE-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7807" name="glyphosate degradation III"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-DME-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-BTA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-CEL-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8259" name="arsenic detoxification (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7517" name="brassicicene C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DME-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DDI-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DDI-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-GGA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7399" name="methylphosphonate degradation II"/>
            <pathway-xref db="Reactome" id="R-CEL-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-DDI-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-HSA-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DME-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DME-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="MetaCyc" id="PWY-6147" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DDI-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7206" name="pyrimidine deoxyribonucleotides dephosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-CEL-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-7198" name="pyrimidine deoxyribonucleotides de novo biosynthesis IV"/>
            <pathway-xref db="MetaCyc" id="PWY-5196" name="factor 430 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SSC-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-1722" name="formate assimilation into 5,10-methylenetetrahydrofolate"/>
            <pathway-xref db="Reactome" id="R-SSC-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-BTA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-MMU-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7072" name="hopanoid biosynthesis (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DME-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-RNO-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-SSC-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-8301" name="S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-CEL-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DME-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-PFA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3sfzA01</model-ac>
        <locations>
          <hmmer3-location env-end="635" env-start="455" post-processed="true" score="51.4" evalue="3.6E-13" hmm-start="22" hmm-end="172" hmm-length="183" hmm-bounds="COMPLETE" start="455" end="635">
            <location-fragments>
              <hmmer3-location-fragment start="455" end="635" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="Polar" start="21" end="35">
            <location-fragments>
              <mobidblite-location-fragment start="21" end="35" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="" start="1" end="35">
            <location-fragments>
              <mobidblite-location-fragment start="1" end="35" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <panther-match evalue="3.9E-214" familyName="GH25853P" score="725.7">
        <signature ac="PTHR19871:SF14" name="GH25853P">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR19871:SF14</model-ac>
        <locations>
          <panther-location env-start="122" env-end="1340" hmm-start="6" hmm-end="1214" hmm-length="1474" hmm-bounds="INCOMPLETE" start="127" end="1310">
            <location-fragments>
              <panther-location-fragment start="127" end="1310" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <panther-match evalue="3.9E-214" familyName="GH25853P" score="725.7">
        <signature ac="PTHR19871" name="BETA TRANSDUCIN-RELATED PROTEIN">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR19871</model-ac>
        <locations>
          <panther-location env-start="122" env-end="1340" hmm-start="6" hmm-end="1214" hmm-length="1474" hmm-bounds="INCOMPLETE" start="127" end="1310">
            <location-fragments>
              <panther-location-fragment start="127" end="1310" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <rpsblast-match>
        <signature ac="cd00009" desc="AAA" name="AAA">
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd00009</model-ac>
        <locations>
          <rpsblast-location evalue="4.28325E-6" score="45.9851" start="477" end="515">
            <location-fragments>
              <rpsblast-location-fragment start="477" end="515" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites>
              <rpsblast-site description="Walker A motif" numLocations="8">
                <site-locations>
                  <site-location residue="G" start="500" end="500"/>
                  <site-location residue="P" start="501" end="501"/>
                  <site-location residue="T" start="507" end="507"/>
                  <site-location residue="K" start="506" end="506"/>
                  <site-location residue="G" start="505" end="505"/>
                  <site-location residue="G" start="503" end="503"/>
                  <site-location residue="G" start="502" end="502"/>
                  <site-location residue="C" start="504" end="504"/>
                </site-locations>
              </rpsblast-site>
            </sites>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <superfamilyhmmer3-match evalue="4.32E-39">
        <signature ac="SSF50998" name="Quinoprotein alcohol dehydrogenase-like">
          <entry ac="IPR011047" desc="Quinoprotein alcohol dehydrogenase-like superfamily" name="Quinoprotein_ADH-like_supfam" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-282" name="cuticular wax biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7620" name="naphthalene degradation (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SCE-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="MetaCyc" id="PWY-7636" name="astaxanthin biosynthesis (flowering plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="MetaCyc" id="PWY-8033" name="aureothin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-DRE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8044" name="cyclohexane-1-carboxyl-CoA biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6457" name="cinnamoyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8179" name="platensimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SPO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7780" name="butane degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8034" name="spectinabilin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-HSA-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="MetaCyc" id="PWY-6926" name="pyrethrin I biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6420" name="pyrroloquinoline quinone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8110" name="L-dopa degradation II (bacterial)"/>
            <pathway-xref db="Reactome" id="R-DRE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SCE-141405" name="Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components"/>
            <pathway-xref db="Reactome" id="R-DRE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-5927" name="(4S)-carveol and (4S)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7778" name="2-methylpropene degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-165159" name="MTOR signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-5922" name="(4R)-carveol and (4R)-dihydrocarveol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-735" name="jasmonic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7300" name="ecdysone and 20-hydroxyecdysone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6464" name="polyvinyl alcohol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8293" name="alazopeptin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7536" name="2-amino-3-hydroxycyclopent-2-enone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6873" name="long chain fatty acid ester synthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-2582" name="brassinosteroid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5958" name="acridone alkaloid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="MetaCyc" id="PWY-7462" name="3,3'-disulfanediyldipropannoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7165" name="L-ascorbate biosynthesis VIII (engineered pathway)"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7779" name="methyl tert-butyl ether degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7007" name="methyl ketone biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-XTR-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6670" name="citronellol degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5924" name="limonene degradation II (L-limonene)"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DRE-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-5136" name="fatty acid beta-oxidation II (plant peroxisome)"/>
            <pathway-xref db="Reactome" id="R-SPO-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DME-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-SPO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5748" name="gamma-coniciene and coniine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5923" name="limonene degradation I (D-limonene)"/>
            <pathway-xref db="Reactome" id="R-CEL-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-6593" name="sulfoacetate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DRE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5644" name="4-nitrotoluene degradation II"/>
            <pathway-xref db="Reactome" id="R-SCE-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-CEL-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SCE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SPO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6817" name="lambda-carrageenan degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6966" name="methanol oxidation to formaldehyde I"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7288" name="fatty acid beta-oxidation VII (yeast peroxisome)"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-CEL-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-301" name="cyclohexane-1-carboxylate degradation (anaerobic)"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0047890</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="560" start="1010" end="1321">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="1010" end="1321" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
      <superfamilyhmmer3-match evalue="6.83E-17">
        <signature ac="SSF52540" name="P-loop containing nucleoside triphosphate hydrolases">
          <entry ac="IPR027417" desc="P-loop containing nucleoside triphosphate hydrolase" name="P-loop_NTPase" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="MetaCyc" id="PWY-8238" name="24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-SCE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SSC-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-HSA-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6973" name="dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SCE-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-7177" name="UTP and CTP dephosphorylation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7631" name="arctigenin and isoarctigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-DME-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DDI-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9684325" name="Maturation of replicase proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-BTA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-DME-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SPO-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9617324" name="Negative regulation of NMDA receptor-mediated neuronal transmission"/>
            <pathway-xref db="MetaCyc" id="PWY-2821" name="glucosinolate biosynthesis from phenylalanine"/>
            <pathway-xref db="Reactome" id="R-SSC-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-3961" name="phosphopantothenate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-RNO-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6526" name="limonene degradation III (to perillate)"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-DRE-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8283" name="lipid IVA biosynthesis (generic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7591" name="okenone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CEL-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-CEL-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DDI-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-HSA-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DDI-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DDI-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DME-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-CEL-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-GGA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-XTR-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DME-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-PFA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-BTA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-SPO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SCE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-MMU-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-5070" name="gibberellin biosynthesis I (non C-3, non C-13 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-PFA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6932" name="selenate reduction"/>
            <pathway-xref db="Reactome" id="R-RNO-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-SPO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9636569" name="Suppression of autophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-SSC-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DRE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2161541" name="Abacavir metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-5047" name="gibberellin biosynthesis IV (Gibberella fujikuroi)"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SCE-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DDI-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-SSC-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DDI-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-PFA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-GGA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7219" name="adenosine ribonucleotides de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-GGA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-CEL-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-PFA-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DDI-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-HSA-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CFA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SSC-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-GGA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-DRE-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-8106" name="queuosine biosynthesis III (queuosine salvage)"/>
            <pathway-xref db="Reactome" id="R-GGA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-SCE-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-DME-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CEL-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SSC-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SSC-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="MetaCyc" id="PWY-7752" name="gadusol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-BTA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SCE-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-DDI-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-PFA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-MMU-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-CFA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-RNO-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SCE-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SPO-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-RNO-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-DME-3371511" name="HSF1 activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7498" name="phenylpropanoids methylation (ice plant)"/>
            <pathway-xref db="Reactome" id="R-HSA-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-DRE-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5729" name="vestitol and sativan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-SPO-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-BTA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-HSA-5632928" name="Defective Mismatch Repair Associated With MSH2"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8148" name="NADP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DME-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CFA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-GGA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CEL-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-RNO-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7977" name="L-methionine biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-SPO-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-GGA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-BTA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-SCE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7363" name="papaverine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-HSA-5649702" name="APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8076" name="8-O-methylated benzoxazinoid glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-GGA-171007" name="p38MAPK events"/>
            <pathway-xref db="MetaCyc" id="PWY-7534" name="gliotoxin inactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CFA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DRE-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-CEL-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7643" name="coniferyl alcohol 9-methyl ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DRE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SSC-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-CEL-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8943723" name="Regulation of PTEN mRNA translation"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-DDI-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DRE-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-DME-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7379" name="mRNA capping II"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="MetaCyc" id="PWY-4021" name="beta-alanine betaine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7391" name="isoprene biosynthesis II (engineered)"/>
            <pathway-xref db="Reactome" id="R-DME-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-6383" name="mono-trans, poly-cis decaprenyl phosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-SSC-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SPO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DDI-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-PFA-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="MetaCyc" id="PWY-5530" name="sorbitol biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-HSA-2408550" name="Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-MMU-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-SCE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6281" name="L-selenocysteine biosynthesis II (archaea and eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DRE-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-CFA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CFA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-DDI-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-CFA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="MetaCyc" id="PWY-6998" name="CDP-D-arabitol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="MetaCyc" id="PWY-8260" name="roxarsone degradation I"/>
            <pathway-xref db="Reactome" id="R-DME-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-DDI-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9694786" name="Transcription of SARS-CoV-2 sgRNAs"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CFA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-351451" name="Homologous recombination repair of replication-dependent double-strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DRE-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-351433" name="ATM mediated phosphorylation of repair proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-MMU-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-7301" name="dTDP-4-O-demethyl-beta-L-noviose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7220" name="adenosine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SCE-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DRE-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DDI-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-922" name="mevalonate pathway I (eukaryotes and bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-350407" name="RHO1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2201" name="folate transformations I"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7377" name="cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)"/>
            <pathway-xref db="MetaCyc" id="PWY-6581" name="spirilloxanthin and 2,2'-diketo-spirilloxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5684045" name="Defective ABCD1 causes ALD"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6795" name="diacylglyceryl-N,N,N-trimethylhomoserine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7248" name="pectin degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-MMU-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DDI-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-GGA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-DME-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6086" name="4-chloro-2-methylphenoxyacetate degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-69091" name="Polymerase switching"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6421" name="arsenate detoxification IV (mycothiol)"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6707" name="gallate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-SCE-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-XTR-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5748" name="gamma-coniciene and coniine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-BTA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8171" name="molybdenum cofactor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-7691" name="10,13-epoxy-11-methyl-octadecadienoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DRE-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5209" name="methyl-coenzyme M oxidation to CO2"/>
            <pathway-xref db="Reactome" id="R-CFA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-DDI-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-HSA-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7904" name="tRNA-uridine 2-thiolation (thermophilic bacteria)"/>
            <pathway-xref db="Reactome" id="R-CEL-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SCE-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DRE-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="Reactome" id="R-RNO-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-RNO-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-CEL-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-1222387" name="Tolerance of reactive oxygen produced by macrophages"/>
            <pathway-xref db="MetaCyc" id="PWY-7250" name="[2Fe-2S] iron-sulfur cluster biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-CFA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-CFA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-111464" name="SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-SCE-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7205" name="CMP phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-CFA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5287" name="sanguinarine and macarpine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DDI-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-SCE-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-SCE-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DDI-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-CEL-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-7972" name="adenosylcobinamide-GDP salvage from cobinamide II"/>
            <pathway-xref db="MetaCyc" id="PWY-5109" name="propanoate fermentation to 2-methylbutanoate"/>
            <pathway-xref db="Reactome" id="R-DME-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DDI-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-BTA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-XTR-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7227" name="adenosine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SSC-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7183" name="pyrimidine nucleobases salvage I"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-1281" name="sulfoacetaldehyde degradation I"/>
            <pathway-xref db="Reactome" id="R-CEL-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683678" name="Defective ABCA3 causes SMDP3"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-DDI-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-CEL-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7298" name="nevadensin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-CFA-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-SPO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DDI-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-DME-216167" name="Nuclear CI is degraded"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SPO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-GGA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-RNO-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-HSA-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-GGA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7226" name="guanosine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-CEL-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-BTA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DRE-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6797" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus)"/>
            <pathway-xref db="Reactome" id="R-DME-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-DRE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-SCE-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-DDI-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-DRE-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="MetaCyc" id="PWY-7962" name="adenosylcobinamide-GDP biosynthesis from cobyrinate a,c-diamide"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DDI-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-CFA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-DRE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1912420" name="Pre-NOTCH Processing in Golgi"/>
            <pathway-xref db="Reactome" id="R-HSA-8948700" name="Competing endogenous RNAs (ceRNAs) regulate PTEN translation"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="MetaCyc" id="PWY-8031" name="epiberberine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-PFA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-GGA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-7007" name="methyl ketone biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-CEL-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5497" name="purine nucleobases degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-CFA-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CFA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-BTA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7742" name="phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-SCE-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SCE-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-DME-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-SPO-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SPO-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-SPO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-4161" name="superpathway of benzoxazinoid glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6398" name="melatonin degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SSC-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-HSA-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-7274" name="D-cycloserine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-6339" name="syringate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8073" name="lipid IVA biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-SCE-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-DME-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-GGA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DDI-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-HSA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-8934593" name="Regulation of RUNX1 Expression and Activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5301" name="ajmaline and sarpagine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DRE-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-RNO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-6802953" name="RAS signaling downstream of NF1 loss-of-function variants"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-GGA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-CFA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="MetaCyc" id="PWY-5083" name="NAD(P)/NADPH interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-DDI-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DRE-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SCE-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SCE-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DME-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DRE-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7163" name="polymethylated kaempferol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-SCE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-SCE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-BTA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-SSC-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-HSA-5682294" name="Defective ABCA12 causes ARCI4B"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-CEL-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-GGA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-CEL-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-BTA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-RNO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-CEL-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6502" name="8-oxo-(d)GTP detoxification I"/>
            <pathway-xref db="Reactome" id="R-SPO-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-DDI-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-GGA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="MetaCyc" id="PWY-6545" name="pyrimidine deoxyribonucleotides de novo biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1362277" name="Transcription of E2F targets under negative control by DREAM complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-SSC-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-5773" name="gossypol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5690338" name="Defective ABCC6 causes PXE"/>
            <pathway-xref db="Reactome" id="R-GGA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-BTA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6154" name="autoinducer AI-2 biosynthesis II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-DDI-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-CEL-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-8245" name="lipid IVA biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-163359" name="Glucagon signaling in metabolic regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-PFA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-421203" name="De novo synthesis of AMP"/>
            <pathway-xref db="Reactome" id="R-HSA-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="MetaCyc" id="PWY-6369" name="inositol diphosphates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-PFA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="MetaCyc" id="PWY-7905" name="Escherichia coli serotype O:9a O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-167160" name="RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-CEL-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DRE-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-SSC-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5362768" name="Hh mutants are degraded by ERAD"/>
            <pathway-xref db="MetaCyc" id="PWY-7741" name="phthiocerol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SSC-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-SPO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CFA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688399" name="Defective ABCA3 causes SMDP3"/>
            <pathway-xref db="Reactome" id="R-HSA-9613829" name="Chaperone Mediated Autophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CFA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-HSA-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-XTR-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-XTR-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-GGA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DME-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-DRE-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8104" name="yangonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-RNO-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-BTA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-DDI-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-CEL-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-HSA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-CFA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-DRE-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-RNO-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-BTA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-SCE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-PFA-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-RNO-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-BTA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8138" name="polyphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-SCE-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-3841" name="folate transformations II (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7185" name="UTP and CTP dephosphorylation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-HSA-1221632" name="Meiotic synapsis"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-RNO-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-DME-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-DRE-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-DRE-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-GGA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5679096" name="Defective ABCG5 causes sitosterolemia"/>
            <pathway-xref db="Reactome" id="R-SCE-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-GGA-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-DME-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5059" name="pinobanksin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6835" name="6-gingerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-SSC-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-BTA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-981" name="salicylate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SSC-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DME-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-CEL-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="MetaCyc" id="PWY-6917" name="vernolate biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-DDI-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-PFA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DME-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-CEL-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-6519" name="8-amino-7-oxononanoate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CFA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8289" name="dZTP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-DDI-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-MMU-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-CEL-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-SCE-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-SCE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-538864" name="Degradation of CRY"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-DRE-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-GGA-265976" name="Homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8986944" name="Transcriptional Regulation by MECP2"/>
            <pathway-xref db="Reactome" id="R-DDI-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-SPO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DDI-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7181" name="pyrimidine deoxyribonucleosides degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-351465" name="Fanconi Anemia Pathway in DNA repair"/>
            <pathway-xref db="Reactome" id="R-CFA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6477" name="gibberellin inactivation II (methylation)"/>
            <pathway-xref db="Reactome" id="R-DDI-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-MMU-74217" name="Purine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-CFA-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-DDI-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-DRE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-MMU-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-CFA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-CEL-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7980" name="ATP biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5679001" name="Defective ABCC2 causes DJS"/>
            <pathway-xref db="Reactome" id="R-DME-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-DME-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="MetaCyc" id="PWY-6978" name="plastoquinol-9 biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-GGA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-GGA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-RNO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DRE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-DRE-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-RNO-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SPO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7901" name="glucosinolate biosynthesis from tyrosine"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-5632927" name="Defective Mismatch Repair Associated With MSH3"/>
            <pathway-xref db="Reactome" id="R-PFA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-7975" name="adenosylcobalamin biosynthesis from adenosylcobinamide-GDP II"/>
            <pathway-xref db="Reactome" id="R-DRE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9670615" name="Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"/>
            <pathway-xref db="MetaCyc" id="PWY-8179" name="platensimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7524" name="mevalonate pathway III (Thermoplasma)"/>
            <pathway-xref db="Reactome" id="R-DME-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-DME-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-CFA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-SSC-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SSC-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-SSC-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SCE-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-5693554" name="Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"/>
            <pathway-xref db="MetaCyc" id="PWY-7483" name="elloramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-DRE-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7564" name="bacimethrin and bacimethrin pyrophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-BTA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-GGA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-SPO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DRE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DDI-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-SPO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DDI-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-GGA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-HSA-9662834" name="CD163 mediating an anti-inflammatory response"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6981" name="chitin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-111463" name="SMAC (DIABLO) binds to IAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DRE-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-RNO-112308" name="Presynaptic depolarization and calcium channel opening"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DDI-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-SCE-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SPO-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6689" name="tRNA splicing I"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-DME-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7292" name="oleate beta-oxidation (thioesterase-dependent, yeast)"/>
            <pathway-xref db="Reactome" id="R-RNO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SSC-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CFA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-9635465" name="Suppression of apoptosis"/>
            <pathway-xref db="Reactome" id="R-HSA-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SCE-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-SSC-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DDI-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-SCE-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-SSC-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="Reactome" id="R-MMU-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-BTA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2083" name="isoflavonoid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SCE-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DRE-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="MetaCyc" id="PWY-8264" name="arsenate detoxification I"/>
            <pathway-xref db="Reactome" id="R-DME-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-DDI-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7224" name="purine deoxyribonucleosides salvage"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DRE-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-5928" name="(4R)-carvone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-SSC-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-SSC-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7104" name="dTDP-beta-L-megosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-CEL-156902" name="Peptide chain elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-HSA-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-MMU-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-GGA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-BTA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-MMU-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-6427" name="rot-2'-enonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7931" name="brominated pyrroles biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8117" name="colibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-HSA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-SCE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DME-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-HSA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-DDI-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SSC-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-GGA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-6683" name="assimilatory sulfate reduction III"/>
            <pathway-xref db="Reactome" id="R-CEL-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DME-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-GGA-352882" name="Glycolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-PFA-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-162588" name="Budding and maturation of HIV virion"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-BTA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DRE-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-GGA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SCE-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="Reactome" id="R-CFA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-SCE-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-XTR-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8083" name="domoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-BTA-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-SSC-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7127" name="CDP-D-mannitol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7805" name="(aminomethyl)phosphonate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-6409" name="pyoverdine I biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-DRE-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5665" name="vanillin biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-SCE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-5723" name="Rubisco shunt"/>
            <pathway-xref db="Reactome" id="R-SSC-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-CFA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-SSC-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SCE-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-5678895" name="Defective CFTR causes cystic fibrosis"/>
            <pathway-xref db="Reactome" id="R-SPO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-CEL-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-DME-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-5683177" name="Defective ABCC8 can cause hypo- and hyper-glycemias"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-DDI-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-CEL-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="MetaCyc" id="PWY-7539" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia)"/>
            <pathway-xref db="Reactome" id="R-HSA-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-7380" name="biotin biosynthesis from 8-amino-7-oxononanoate II"/>
            <pathway-xref db="Reactome" id="R-CFA-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9674519" name="Defective F8 sulfation at Y1699"/>
            <pathway-xref db="MetaCyc" id="PWY-8015" name="glycine degradation (reductive Stickland reaction)"/>
            <pathway-xref db="Reactome" id="R-DME-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-983189" name="Kinesins"/>
            <pathway-xref db="MetaCyc" id="PWY-4061" name="glutathione-mediated detoxification I"/>
            <pathway-xref db="Reactome" id="R-BTA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-DME-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-MMU-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-601" name="glucosinolate biosynthesis from tryptophan"/>
            <pathway-xref db="Reactome" id="R-SSC-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-CEL-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-5340" name="sulfate activation for sulfonation"/>
            <pathway-xref db="Reactome" id="R-SCE-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="MetaCyc" id="PWY-7159" name="3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7199" name="pyrimidine deoxyribonucleosides salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DME-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-3359475" name="Defective MMAA causes methylmalonic aciduria type cblA"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-SPO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-8172" name="10-methylstearate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5757" name="fosfomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-CFA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SPO-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-CEL-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8080" name="kainate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DRE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-SPO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DRE-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-SPO-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7704" name="viridicatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SCE-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-112126" name="ALKBH3 mediated reversal of alkylation damage"/>
            <pathway-xref db="Reactome" id="R-CEL-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-DDI-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-DME-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-7325" name="salvigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-72203" name="Processing of Capped Intron-Containing Pre-mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="MetaCyc" id="PWY-7629" name="yatein biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-GGA-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-DME-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-RNO-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-CEL-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-933541" name="TRAF6 mediated IRF7 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-SSC-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SPO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-390471" name="Association of TriC/CCT with target proteins during biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DDI-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-SPO-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-BTA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CFA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-420092" name="Glucagon-type ligand receptors"/>
            <pathway-xref db="MetaCyc" id="PWY-7268" name="cytosolic NADPH production (yeast)"/>
            <pathway-xref db="Reactome" id="R-CFA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-CFA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SSC-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-HSA-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-7840" name="gala-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-7184" name="pyrimidine deoxyribonucleotides de novo biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7886" name="cell-surface glycoconjugate-linked phosphocholine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6286" name="spheroidene and spheroidenone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7668" name="apicidin F biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-7197" name="pyrimidine deoxyribonucleotide phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SPO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-SPO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DRE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-MMU-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5682910" name="LGI-ADAM interactions"/>
            <pathway-xref db="Reactome" id="R-DDI-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-DME-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="MetaCyc" id="PWY-5443" name="aminopropanol phosphate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-209159" name="Assembly of the CI containing complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-SSC-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-7667" name="apicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DME-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-MMU-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-7398" name="coumarins biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="MetaCyc" id="PWY-7734" name="quinoxaline-2-carboxylate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-BTA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7285" name="methylwyosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-DME-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-BTA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SPO-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-HSA-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3560796" name="Defective PAPSS2 causes SEMD-PA"/>
            <pathway-xref db="Reactome" id="R-SCE-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-HSA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DRE-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5368286" name="Mitochondrial translation initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-72203" name="Processing of Capped Intron-Containing Pre-mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="MetaCyc" id="PWY-7210" name="pyrimidine deoxyribonucleotides biosynthesis from CTP"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-1187" name="glucosinolate biosynthesis from homomethionine"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-RNO-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-4202" name="arsenic detoxification (mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-7851" name="coenzyme A biosynthesis II (eukaryotic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DME-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-SSC-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-DME-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2408557" name="Selenocysteine synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DRE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-CEL-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-7705" name="4'-methoxyviridicatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DRE-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-167158" name="Formation of the HIV-1 Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-PFA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-HSA-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6416" name="quinate degradation II"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6637" name="sulfolactate degradation II"/>
            <pathway-xref db="Reactome" id="R-CEL-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-GGA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7717" name="3-hydroxy-4-methyl-anthranilate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7376" name="cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation)"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-8949613" name="Cristae formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7655" name="dechlorogriseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7607" name="meleagrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6585" name="2-methylketone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8101" name="arsenate detoxification II"/>
            <pathway-xref db="Reactome" id="R-SCE-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DRE-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7765" name="3-hydroxy-4-methyl-anthranilate biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-GGA-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-GGA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-7155" name="7-dehydroporiferasterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-912446" name="Meiotic recombination"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5336415" name="Uptake and function of diphtheria toxin"/>
            <pathway-xref db="Reactome" id="R-SSC-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-CEL-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5649702" name="APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-GGA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-196783" name="Coenzyme A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2564830" name="Cytosolic iron-sulfur cluster assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4621" name="arsenic detoxification (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-RNO-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-MMU-169911" name="Regulation of Apoptosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-SCE-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7193" name="pyrimidine ribonucleosides salvage I"/>
            <pathway-xref db="Reactome" id="R-DME-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-RNO-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-DDI-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6919" name="neopentalenoketolactone and pentalenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-RNO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-SCE-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7439" name="dTDP-beta-L-evernitrose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-BTA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SSC-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-DME-432626" name="Circadian Clock pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="Reactome" id="R-SSC-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-9708296" name="tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="MetaCyc" id="PWY-5531" name="3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-CFA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-GGA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-HSA-1222449" name="Mtb iron assimilation by chelation"/>
            <pathway-xref db="Reactome" id="R-RNO-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="MetaCyc" id="PWY-7187" name="pyrimidine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-GGA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7649" name="3-hydroxy-L-homotyrosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DME-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-DME-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-RNO-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-SPO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-BTA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8129" name="cell-surface glycoconjugate-linked phosphonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-DME-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7440" name="dTDP-beta-L-4-epi-vancosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-DME-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-SCE-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-SCE-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8167" name="bis(tungstenpterin) cofactor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-DME-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5621480" name="Dectin-2 family"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7608" name="neoxaline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6085" name="2,4-dichlorophenoxyacetate degradation"/>
            <pathway-xref db="Reactome" id="R-XTR-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DME-110523" name="TOR signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-GGA-217106" name="Chk1-controlled and DNA-damage induced centrosome duplication"/>
            <pathway-xref db="MetaCyc" id="PWY-7221" name="guanosine ribonucleotides de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-DDI-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-SSC-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8095" name="5-methoxy-6-methylbenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MTU-936635" name="Sulfate assimilation"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-SPO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-2681" name="trans-zeatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DRE-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-GGA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7648" name="3-hydroxy-4-methyl-proline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5693579" name="Homologous DNA Pairing and Strand Exchange"/>
            <pathway-xref db="Reactome" id="R-DME-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="MetaCyc" id="PWY-7402" name="benzoate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="Reactome" id="R-DRE-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="MetaCyc" id="PWY-5526" name="bacteriochlorophyll a biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8184" name="L-isoleucine degradation III (oxidative Stickland reaction)"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7176" name="UTP and CTP de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4983" name="nitric oxide biosynthesis II (mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-CFA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-CEL-983712" name="Ion channel transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8096" name="5-methoxybenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-SCE-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-SSC-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5678771" name="Defective ABCB4 causes PFIC3, ICP3 and GBD1"/>
            <pathway-xref db="Reactome" id="R-SPO-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DDI-3371497" name="HSP90 chaperone cycle for steroid hormone receptors (SHR)"/>
            <pathway-xref db="Reactome" id="R-MMU-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DRE-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DDI-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-BTA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-GGA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-DME-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-BTA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-CEL-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5305" name="bixin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-DME-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DRE-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-8876725" name="Protein methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7614" name="methiin metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-918233" name="TRAF3-dependent IRF activation pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SPO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-CEL-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SCE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DME-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7826" name="Amaryllidacea alkaloids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-BTA-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-SCE-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5278" name="sulfite oxidation III"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-BTA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6995" name="5-hydroxymethylfurfural degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-SSC-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-HSA-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SPO-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-XTR-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-GGA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SCE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DRE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-5035" name="gibberellin biosynthesis III (early C-13 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-SPO-8876725" name="Protein methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7733" name="3-hydroxyquinaldate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-GGA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-SPO-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-CFA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-SSC-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-SCE-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-6997" name="furfural degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5683371" name="Defective ABCB6 causes MCOPCB7"/>
            <pathway-xref db="Reactome" id="R-RNO-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-SCE-189451" name="Heme biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CFA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9694271" name="Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)"/>
            <pathway-xref db="Reactome" id="R-DME-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-DME-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-CFA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-GGA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8303" name="reductive glycine pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-SPO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DME-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="MetaCyc" id="PWY-7789" name="erythritol degradation I"/>
            <pathway-xref db="Reactome" id="R-GGA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-181" name="photorespiration"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-BTA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964058" name="HDL remodeling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392851" name="Prostacyclin signalling through prostacyclin receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9649913" name="RAS GTPase cycle mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-RNO-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7948" name="4-oxopentanoate degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-CEL-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="MetaCyc" id="PWY-6626" name="cytidine-5'-diphosphate-glycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-RNO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-SPO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-GGA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DRE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1222538" name="Tolerance by Mtb to nitric oxide produced by macrophages"/>
            <pathway-xref db="Reactome" id="R-SCE-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5632968" name="Defective Mismatch Repair Associated With MSH6"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1834941" name="STING mediated induction of host immune responses"/>
            <pathway-xref db="Reactome" id="R-MMU-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="MetaCyc" id="PWY-6613" name="tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"/>
            <pathway-xref db="Reactome" id="R-MMU-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7751" name="shinorine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-MMU-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-MMU-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-RNO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-CFA-73856" name="RNA Polymerase II Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5683329" name="Defective ABCD4 causes MAHCJ"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-MMU-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-SSC-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-983712" name="Ion channel transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-CEL-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-DME-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-CEL-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-XTR-69052" name="Switching of origins to a post-replicative state"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-DME-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6976" name="dTDP-beta-L-mycarose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="MetaCyc" id="PWY-7342" name="superpathway of nicotine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-6163" name="chorismate biosynthesis from 3-dehydroquinate"/>
            <pathway-xref db="Reactome" id="R-RNO-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DDI-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-381753" name="Olfactory Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-DRE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DME-216119" name="Activation of CI"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-5576893" name="Phase 2 - plateau phase"/>
            <pathway-xref db="Reactome" id="R-DRE-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CEL-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-DME-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5765" name="1,3,5-trimethoxybenzene biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-5625970" name="RHO GTPases activate KTN1"/>
            <pathway-xref db="Reactome" id="R-DME-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-SSC-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-SPO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3359478" name="Defective MUT causes methylmalonic aciduria mut type"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="MetaCyc" id="PWY-6313" name="serotonin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-GGA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-RNO-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-DDI-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SSC-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-SSC-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DRE-5624138" name="Trafficking of myristoylated proteins to the cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-389977" name="Post-chaperonin tubulin folding pathway"/>
            <pathway-xref db="Reactome" id="R-DME-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-CEL-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5678520" name="Defective ABCB11 causes PFIC2 and BRIC2"/>
            <pathway-xref db="Reactome" id="R-SCE-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-113507" name="E2F-enabled inhibition of pre-replication complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DME-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-SCE-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-DME-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-SSC-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-6567" name="chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-6199" name="quercetin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-GGA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="Reactome" id="R-SCE-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9694614" name="Attachment and Entry"/>
            <pathway-xref db="Reactome" id="R-HSA-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-DRE-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7076" name="3,5-dimethoxytoluene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-SPO-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-CFA-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="MetaCyc" id="PWY-5107" name="phytol salvage pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-DME-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-SPO-9668328" name="Sealing of the nuclear envelope (NE) by ESCRT-III"/>
            <pathway-xref db="Reactome" id="R-HSA-180585" name="Vif-mediated degradation of APOBEC3G"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-9678110" name="Attachment and Entry"/>
            <pathway-xref db="Reactome" id="R-DME-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-SCE-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-68616" name="Assembly of the ORC complex at the origin of replication"/>
            <pathway-xref db="Reactome" id="R-DRE-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-HSA-844623" name="The IPAF inflammasome"/>
            <pathway-xref db="Reactome" id="R-HSA-6803207" name="TP53 Regulates Transcription of Caspase Activators and Caspases"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-RNO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8100" name="crotonosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7888" name="tRNA-uridine 2-thiolation (cytoplasmic)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-DME-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-GGA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-163767" name="PP2A-mediated dephosphorylation of key metabolic factors"/>
            <pathway-xref db="Reactome" id="R-SCE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-SCE-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-DRE-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-DME-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1606341" name="IRF3 mediated activation of type 1 IFN"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-SSC-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5883" name="ephedrine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DME-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5682113" name="Defective ABCA1 causes TGD"/>
            <pathway-xref db="Reactome" id="R-DME-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-CEL-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-HSA-2470946" name="Cohesin Loading onto Chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-7831" name="ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"/>
            <pathway-xref db="Reactome" id="R-RNO-5651801" name="PCNA-Dependent Long Patch Base Excision Repair"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DRE-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CFA-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-MMU-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-GGA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-GGA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-RNO-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5349" name="esculetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7232" name="gibberellin biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-CEL-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-BTA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DRE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-CEL-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-HSA-5601884" name="PIWI-interacting RNA (piRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SSC-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-SCE-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="MetaCyc" id="PWY-6739" name="pinitol biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-DME-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-9682708" name="Transcription of SARS-CoV-1 sgRNAs"/>
            <pathway-xref db="MetaCyc" id="PWY-5479" name="6-methoxypodophyllotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-1369062" name="ABC transporters in lipid homeostasis"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-HSA-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-MMU-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DME-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-163210" name="Formation of ATP by chemiosmotic coupling"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-SPO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-6164" name="3-dehydroquinate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DDI-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="MetaCyc" id="PWY-7077" name="N-acetyl-D-galactosamine degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DRE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6269" name="superpathway of adenosylcobalamin salvage from cobinamide II"/>
            <pathway-xref db="Reactome" id="R-MMU-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DDI-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-RNO-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-DDI-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-GGA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-BTA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-DDI-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3247509" name="Chromatin modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DME-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-MMU-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-DDI-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-159418" name="Recycling of bile acids and salts"/>
            <pathway-xref db="Reactome" id="R-RNO-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DDI-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-HSA-209563" name="Axonal growth stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-CEL-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1061" name="homogalacturonan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5624958" name="ARL13B-mediated ciliary trafficking of INPP5E"/>
            <pathway-xref db="Reactome" id="R-SPO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9694301" name="Maturation of replicase proteins"/>
            <pathway-xref db="Reactome" id="R-PFA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7909" name="formaldehyde oxidation VII (THF pathway)"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5485" name="pyruvate fermentation to acetate IV"/>
            <pathway-xref db="Reactome" id="R-MMU-983712" name="Ion channel transport"/>
            <pathway-xref db="MetaCyc" id="PWY-2781" name="cis-zeatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DRE-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5678420" name="Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-MMU-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-SCE-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-DDI-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-174362" name="Transport and synthesis of PAPS"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-83936" name="Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-DDI-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DDI-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7031" name="protein N-glycosylation (bacterial)"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-8936459" name="RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"/>
            <pathway-xref db="Reactome" id="R-HSA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6915" name="pentalenolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-SCE-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-9615710" name="Late endosomal microautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-XTR-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-8949613" name="Cristae formation"/>
            <pathway-xref db="Reactome" id="R-DME-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="MetaCyc" id="PWY-6436" name="perillyl aldehyde biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-XTR-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7533" name="gliotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-GGA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-163841" name="Gamma carboxylation, hypusine formation and arylsulfatase activation"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-GGA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-2453864" name="Retinoid cycle disease events"/>
            <pathway-xref db="Reactome" id="R-RNO-844455" name="The NLRP1 inflammasome"/>
            <pathway-xref db="Reactome" id="R-BTA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-DME-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-CEL-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SSC-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6261" name="thyroid hormone metabolism II (via conjugation and/or degradation)"/>
            <pathway-xref db="Reactome" id="R-MMU-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="MetaCyc" id="PWY-7739" name="aucuparin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-429958" name="mRNA decay by 3' to 5' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-164944" name="Nef and signal transduction"/>
            <pathway-xref db="Reactome" id="R-DDI-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-68867" name="Assembly of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DRE-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-DDI-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-CFA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-191273" name="Cholesterol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6787450" name="tRNA modification in the mitochondrion"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-72187" name="mRNA 3'-end processing"/>
            <pathway-xref db="Reactome" id="R-SCE-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-DDI-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-SPO-190873" name="Gap junction degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SPO-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DME-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-HSA-1369007" name="Mitochondrial ABC transporters"/>
            <pathway-xref db="Reactome" id="R-RNO-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-DRE-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-163358" name="PKA-mediated phosphorylation of key metabolic factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SCE-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DDI-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SCE-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-RNO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-MMU-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-GGA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7079" name="geodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CEL-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-DME-350480" name="Activation of non-muscle Myosin II"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8876725" name="Protein methylation"/>
            <pathway-xref db="Reactome" id="R-SPO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-933543" name="NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"/>
            <pathway-xref db="Reactome" id="R-GGA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-DDI-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-MMU-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-DDI-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-HSA-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-111458" name="Formation of apoptosome"/>
            <pathway-xref db="Reactome" id="R-DRE-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7971" name="adenosylcobinamide-GDP salvage from cobinamide I"/>
            <pathway-xref db="Reactome" id="R-RNO-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-72662" name="Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"/>
            <pathway-xref db="Reactome" id="R-CFA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6568" name="dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="Reactome" id="R-SCE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="MetaCyc" id="PWY-5030" name="L-histidine degradation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DDI-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-432395" name="Degradation of TIM"/>
            <pathway-xref db="Reactome" id="R-HSA-3371511" name="HSF1 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SPO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-352875" name="Gluconeogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-XTR-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-DME-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-DME-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5358493" name="Synthesis of diphthamide-EEF2"/>
            <pathway-xref db="Reactome" id="R-RNO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-CEL-1268020" name="Mitochondrial protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-DDI-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-CEL-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-CEL-71032" name="Propionyl-CoA catabolism"/>
            <pathway-xref db="Reactome" id="R-DDI-6811436" name="COPI-independent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6045" name="methylthiopropanonate degradation II (demethylation)"/>
            <pathway-xref db="Reactome" id="R-DRE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8077" name="ginkgotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-5693568" name="Resolution of D-loop Structures through Holliday Junction Intermediates"/>
            <pathway-xref db="Reactome" id="R-SPO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DME-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-XTR-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8103" name="kavain biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-SPO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-GGA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-CFA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="MetaCyc" id="PWY-5316" name="nicotine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SSC-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SCE-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DME-216217" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6153" name="autoinducer AI-2 biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9706019" name="RHOBTB3 ATPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DME-350368" name="Activation of RHO1 by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-DME-451308" name="Activation of Ca-permeable Kainate Receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693548" name="Sensing of DNA Double Strand Breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-2161517" name="Abacavir transmembrane transport"/>
            <pathway-xref db="Reactome" id="R-RNO-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-3542" name="choline biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1655829" name="Regulation of cholesterol biosynthesis by SREBP (SREBF)"/>
            <pathway-xref db="Reactome" id="R-HSA-196757" name="Metabolism of folate and pterines"/>
            <pathway-xref db="Reactome" id="R-SPO-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-SPO-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7161" name="polymethylated quercetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CEL-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-MMU-193368" name="Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol"/>
            <pathway-xref db="Reactome" id="R-DME-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-MMU-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-5620924" name="Intraflagellar transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-199992" name="trans-Golgi Network Vesicle Budding"/>
            <pathway-xref db="Reactome" id="R-HSA-9694686" name="Replication of the SARS-CoV-2 genome"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-SCE-111457" name="Release of apoptotic factors from the mitochondria"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-GGA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1296025" name="ATP sensitive Potassium channels"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-77595" name="Processing of Intronless Pre-mRNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7729" name="5,6-dimethylbenzimidazole biosynthesis II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-GGA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DME-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-GGA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DDI-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-HSA-8935964" name="RUNX1 regulates expression of components of tight junctions"/>
            <pathway-xref db="MetaCyc" id="PWY-2161" name="folate polyglutamylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7485" name="tetracenomycin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-8086" name="(S)-lactate fermentation to propanoate, acetate and hydrogen"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7222" name="guanosine deoxyribonucleotides de novo biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CEL-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-68689" name="CDC6 association with the ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8964058" name="HDL remodeling"/>
            <pathway-xref db="Reactome" id="R-RNO-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-69091" name="Polymerase switching"/>
            <pathway-xref db="Reactome" id="R-MMU-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-9670613" name="Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-GGA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-DDI-2142691" name="Synthesis of Leukotrienes (LT) and Eoxins (EX)"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-GGA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-SCE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SCE-1222556" name="ROS and RNS production in phagocytes"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-SCE-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-HSA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-SSC-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9682706" name="Replication of the SARS-CoV-1 genome"/>
            <pathway-xref db="Reactome" id="R-CFA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-176974" name="Unwinding of DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-888590" name="GABA synthesis, release, reuptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-SPO-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2046106" name="alpha-linolenic acid (ALA) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6736" name="sulfur volatiles biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5358606" name="Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"/>
            <pathway-xref db="Reactome" id="R-DRE-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7269" name="mitochondrial NADPH production (yeast)"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DME-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-CFA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-5685939" name="HDR through MMEJ (alt-NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-9683439" name="Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)"/>
            <pathway-xref db="Reactome" id="R-MMU-392170" name="ADP signalling through P2Y purinoceptor 12"/>
            <pathway-xref db="Reactome" id="R-HSA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-MMU-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="Reactome" id="R-MMU-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-SSC-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DRE-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-SPO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-CFA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-111469" name="SMAC, XIAP-regulated apoptotic response"/>
            <pathway-xref db="Reactome" id="R-DME-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-MMU-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DME-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MTU-964903" name="Chorismate via Shikimate Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-SSC-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-DME-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="Reactome" id="R-SPO-69166" name="Removal of the Flap Intermediate"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5482" name="pyruvate fermentation to acetate II"/>
            <pathway-xref db="Reactome" id="R-DRE-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-GGA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390247" name="Beta-oxidation of very long chain fatty acids"/>
            <pathway-xref db="Reactome" id="R-SCE-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="MetaCyc" id="PWY-7160" name="polymethylated myricetin biosynthesis (tomato)"/>
            <pathway-xref db="MetaCyc" id="PWY-102" name="gibberellin inactivation I (2beta-hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-CEL-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-72731" name="Recycling of eIF2:GDP"/>
            <pathway-xref db="Reactome" id="R-HSA-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DRE-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-350562" name="Regulation of ornithine decarboxylase (ODC)"/>
            <pathway-xref db="MetaCyc" id="PWY-5036" name="gibberellin biosynthesis II (early C-3 hydroxylation)"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-156584" name="Cytosolic sulfonation of small molecules"/>
            <pathway-xref db="Reactome" id="R-CFA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8098" name="cyclic 2,3-bisphosphoglycerate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-HSA-9633012" name="Response of EIF2AK4 (GCN2) to amino acid deficiency"/>
            <pathway-xref db="Reactome" id="R-MMU-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SPO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-CEL-2142850" name="Hyaluronan biosynthesis and export"/>
            <pathway-xref db="Reactome" id="R-CEL-2468052" name="Establishment of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-73817" name="Purine ribonucleoside monophosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-5627083" name="RHO GTPases regulate CFTR trafficking"/>
            <pathway-xref db="Reactome" id="R-SPO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-SPO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-201722" name="Formation of the beta-catenin:TCF transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5679090" name="Defective ABCG8 causes GBD4 and sitosterolemia"/>
            <pathway-xref db="Reactome" id="R-BTA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-HSA-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-428930" name="Thromboxane signalling through TP receptor"/>
            <pathway-xref db="Reactome" id="R-CFA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-8873719" name="RAB geranylgeranylation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-SCE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111459" name="Activation of caspases through apoptosome-mediated cleavage"/>
            <pathway-xref db="Reactome" id="R-DME-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-SCE-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7807" name="glyphosate degradation III"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-DME-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-BTA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-SPO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-196741" name="Cobalamin (Cbl, vitamin B12) transport and metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-CEL-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8259" name="arsenic detoxification (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7517" name="brassicicene C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DME-6811440" name="Retrograde transport at the Trans-Golgi-Network"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-DDI-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-BTA-9639288" name="Amino acids regulate mTORC1"/>
            <pathway-xref db="Reactome" id="R-DDI-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-GGA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7399" name="methylphosphonate degradation II"/>
            <pathway-xref db="Reactome" id="R-CEL-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-DDI-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-HSA-2559584" name="Formation of Senescence-Associated Heterochromatin Foci (SAHF)"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DME-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DME-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-5626467" name="RHO GTPases activate IQGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-203927" name="MicroRNA (miRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="MetaCyc" id="PWY-6147" name="6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DDI-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7206" name="pyrimidine deoxyribonucleotides dephosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8951936" name="RUNX3 regulates p14-ARF"/>
            <pathway-xref db="Reactome" id="R-CEL-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-7198" name="pyrimidine deoxyribonucleotides de novo biosynthesis IV"/>
            <pathway-xref db="MetaCyc" id="PWY-5196" name="factor 430 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-SSC-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-1722" name="formate assimilation into 5,10-methylenetetrahydrofolate"/>
            <pathway-xref db="Reactome" id="R-SSC-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-MMU-8949664" name="Processing of SMDT1"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5358565" name="Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"/>
            <pathway-xref db="Reactome" id="R-BTA-73614" name="Pyrimidine salvage"/>
            <pathway-xref db="Reactome" id="R-HSA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-RNO-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-MMU-400042" name="Adrenaline,noradrenaline inhibits insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7072" name="hopanoid biosynthesis (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DME-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6790901" name="rRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-RNO-196807" name="Nicotinate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-SSC-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2046105" name="Linoleic acid (LA) metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-8301" name="S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-CEL-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-SCE-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DME-426486" name="Small interfering RNA (siRNA) biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-PFA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0053686</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="277" start="473" end="691">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="473" end="691" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
    </matches>
  </protein>
  <protein>
    <sequence md5="fc0c0c194b8645017acaa40d7e4221aa">MYSRYGIMYDDGIHPGYIDGGASGGGLYEPHVAHRPSIHHSPHLNHAMHPYHANHVAPAANHVMGGAVPDVGKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFNEDIAVFSKQIRQEKPYYIADPEVDSLMVQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGTKPPELGGSTNGDGGTRSNADSTSHTDGASTPDVRPPSSSLSYGGPVNDDVRSPGTPGPLSQPPSSQQTIDGSDPDAIGKWCPRREWSSPPDARATSDAARRGVLYSSVFLGSPGDASNASIGSGEGTGEEDDDTNGKKNQKKRGIFPKVATNILRAWLFQHLTHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVFSPHAGPSGAYSPDGTMGYMMDGQQMMHRPPGDPAFHNQYAHYPAEYYGHHL</sequence>
    <xref id="XP_017774900.1" name="XP_017774900.1 PREDICTED: homeobox protein homothorax isoform X1 [Nicrophorus vespilloides]"/>
    <matches>
      <hmmer2-match evalue="2.8E-12" score="56.8">
        <signature ac="SM00389" name="HOX_1">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00389</model-ac>
        <locations>
          <hmmer2-location score="56.8" evalue="2.8E-12" hmm-start="1" hmm-end="63" hmm-length="63" hmm-bounds="COMPLETE" start="333" end="398">
            <location-fragments>
              <hmmer2-location-fragment start="333" end="398" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer3-match evalue="1.2E-19" score="70.0">
        <signature ac="PF05920" desc="Homeobox KN domain" name="Homeobox_KN">
          <entry ac="IPR008422" desc="Homeobox KN domain" name="Homeobox_KN_domain" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <go-xref category="BIOLOGICAL_PROCESS" db="GO" id="GO:0006355" name="regulation of transcription, DNA-templated"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF05920</model-ac>
        <locations>
          <hmmer3-location env-end="390" env-start="351" post-processed="true" score="70.0" evalue="1.2E-19" hmm-start="1" hmm-end="40" hmm-length="40" hmm-bounds="COMPLETE" start="351" end="390">
            <location-fragments>
              <hmmer3-location-fragment start="351" end="390" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.8E-44" score="150.0">
        <signature ac="PF16493" desc="N-terminal of Homeobox Meis and PKNOX1" name="Meis_PKNOX_N">
          <entry ac="IPR032453" desc="Homeobox protein PKNOX/Meis, N-terminal" name="PKNOX/Meis_N" type="DOMAIN">
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF16493</model-ac>
        <locations>
          <hmmer3-location env-end="193" env-start="109" post-processed="true" score="149.4" evalue="2.6E-44" hmm-start="1" hmm-end="85" hmm-length="86" hmm-bounds="N_TERMINAL_COMPLETE" start="109" end="192">
            <location-fragments>
              <hmmer3-location-fragment start="109" end="192" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="4.8E-37" score="127.4">
        <signature ac="G3DSA:1.10.10.60" name="">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3k2aB00</model-ac>
        <locations>
          <hmmer3-location env-end="402" env-start="336" post-processed="true" score="126.6" evalue="8.4E-37" hmm-start="3" hmm-end="67" hmm-length="67" hmm-bounds="COMPLETE" start="336" end="402">
            <location-fragments>
              <hmmer3-location-fragment start="336" end="402" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="" start="310" end="338">
            <location-fragments>
              <mobidblite-location-fragment start="310" end="338" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="" start="189" end="292">
            <location-fragments>
              <mobidblite-location-fragment start="189" end="292" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="Polar" start="204" end="239">
            <location-fragments>
              <mobidblite-location-fragment start="204" end="239" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <panther-match evalue="1.6E-148" familyName="HOMEOBOX PROTEIN MEIS2" score="506.9">
        <signature ac="PTHR11850:SF47" name="HOMEOBOX PROTEIN MEIS2">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR11850:SF47</model-ac>
        <locations>
          <panther-location env-start="6" env-end="449" hmm-start="5" hmm-end="388" hmm-length="471" hmm-bounds="INCOMPLETE" start="9" end="440">
            <location-fragments>
              <panther-location-fragment start="9" end="440" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <panther-match evalue="1.6E-148" familyName="HOMEOBOX PROTEIN MEIS2" score="506.9">
        <signature ac="PTHR11850" name="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR11850</model-ac>
        <locations>
          <panther-location env-start="6" env-end="449" hmm-start="5" hmm-end="388" hmm-length="471" hmm-bounds="INCOMPLETE" start="9" end="440">
            <location-fragments>
              <panther-location-fragment start="9" end="440" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <profilescan-match>
        <signature ac="PS50071" desc="'Homeobox' domain profile." name="HOMEOBOX_2">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="PROSITE_PROFILES" version="2021_01"/>
        </signature>
        <model-ac>PS50071</model-ac>
        <locations>
          <profilescan-location score="13.539694" start="331" end="394">
            <location-fragments>
              <profilescan-location-fragment start="331" end="394" dc-status="CONTINUOUS"/>
            </location-fragments>
            <alignment>KKNQKKRGIFPKVATNILRAWLFQhltHPYPSEDQKKQLAQDTGLTILQVNNWFINARRRIVQP</alignment>
          </profilescan-location>
        </locations>
      </profilescan-match>
      <rpsblast-match>
        <signature ac="cd00086" desc="homeodomain" name="homeodomain">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd00086</model-ac>
        <locations>
          <rpsblast-location evalue="6.48935E-15" score="66.8832" start="335" end="390">
            <location-fragments>
              <rpsblast-location-fragment start="335" end="390" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites>
              <rpsblast-site description="specific DNA base contacts" numLocations="6">
                <site-locations>
                  <site-location residue="N" start="386" end="386"/>
                  <site-location residue="K" start="336" end="336"/>
                  <site-location residue="I" start="339" end="339"/>
                  <site-location residue="N" start="382" end="382"/>
                  <site-location residue="I" start="385" end="385"/>
                  <site-location residue="R" start="389" end="389"/>
                </site-locations>
              </rpsblast-site>
              <rpsblast-site description="DNA binding site" numLocations="15">
                <site-locations>
                  <site-location residue="G" start="338" end="338"/>
                  <site-location residue="R" start="390" end="390"/>
                  <site-location residue="F" start="340" end="340"/>
                  <site-location residue="R" start="337" end="337"/>
                  <site-location residue="Y" start="360" end="360"/>
                  <site-location residue="N" start="382" end="382"/>
                  <site-location residue="R" start="388" end="388"/>
                  <site-location residue="I" start="385" end="385"/>
                  <site-location residue="R" start="389" end="389"/>
                  <site-location residue="N" start="386" end="386"/>
                  <site-location residue="Q" start="379" end="379"/>
                  <site-location residue="K" start="335" end="335"/>
                  <site-location residue="N" start="381" end="381"/>
                  <site-location residue="K" start="336" end="336"/>
                  <site-location residue="K" start="366" end="366"/>
                </site-locations>
              </rpsblast-site>
            </sites>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <superfamilyhmmer3-match evalue="3.29E-20">
        <signature ac="SSF46689" name="Homeodomain-like">
          <entry ac="IPR009057" desc="Homeobox-like domain superfamily" name="Homeobox-like_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-BTA-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-DRE-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-RNO-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-RNO-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6526" name="limonene degradation III (to perillate)"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-418124" name="Telomere maintenance"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5661" name="GDP-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-RNO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-HSA-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-DRE-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-BTA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5601884" name="PIWI-interacting RNA (piRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-CEL-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6689" name="tRNA splicing I"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-XTR-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-MMU-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-RNO-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-621" name="sucrose degradation III (sucrose invertase)"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-RNO-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5928" name="(4R)-carvone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7250" name="[2Fe-2S] iron-sulfur cluster biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-110329" name="Cleavage of the damaged pyrimidine"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8869496" name="TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2722" name="trehalose degradation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-RNO-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="Reactome" id="R-XTR-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-6436" name="perillyl aldehyde biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-1221632" name="Meiotic synapsis"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-HSA-1368071" name="NR1D1 (REV-ERBA) represses gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-HSA-110328" name="Recognition and association of DNA glycosylase with site containing an affected pyrimidine"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7385" name="1,3-propanediol biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2723" name="trehalose degradation V"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9623433" name="NR1H2 &amp; NR1H3 regulate gene expression to control bile acid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9623433" name="NR1H2 &amp; NR1H3 regulate gene expression to control bile acid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-BTA-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-XTR-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-DRE-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-DRE-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5514" name="UDP-N-acetyl-D-galactosamine biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-DRE-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SPO-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-SPO-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-DME-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0047970</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="82" start="332" end="409">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="332" end="409" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
    </matches>
  </protein>
  <protein>
    <sequence md5="ca1c1eeb3815e1d9a37732b13e54912c">MSEFLADNNVCGQSILLLVSRGNAIISEILRLKDYVPDLFRLSKQDGQKYADIILDFSYFKISEAQEQKIESNEVLRNLDEEFRDNHIDIISRFYFAFESIHTYIKELNCYIDELEDGYYIHQNMETVFADVEGKQLLCEALYLYGTILLLVDAHLEGVVRERLLVSFYRYTPQSNGTENSIDEICKLLRDTGINSKKITNYPEDYFKRIPIKESYVELVLGKLRSDDVYNQLTVYPLTRHRSTALANQAAMLYICLFFSPEILHTQNALMREIVDKYFPDNWVISIYMGFTVNLVENWDSFKAAKLALSNTVENANIKHHSDRNGRVVKELLNETTMLLKEGTVTRDNLLQNINKIVNVVRDCNVAIRWLMLHAICKQGKVEKNKKCKQLRDLVIADSKYEAVIVFKLLLNTSQLELLIKDIYKNLINEKEKRWEELKKESYEMLVELSEIFSGEKPLTRIQKNTNLKNWFLEISKQVDSLDPNLENASVKIDQLIQALEEVQEFHQLSSNMQIIQFLSDTKRCLNHMIRNMKVKEDVLITLQIIGDICYAWDLIDSYTPIMQLGIKREPTLVIKLRAVFLKLGSALEIPLLRINQAHSEDLISVSQYYSRELEIYIRMVLQIIPNAMFEKMARVIEIQTCILKELPTKLEKDKIKEYAQLNERFEFAELTHSISVFSQGMRMMKTTLVGVVYLDPKMLLEDGIRKELVQHISKALHCELIFSAKMKPDELEQRLRSLGNIMDGYKRSFEYIQDYVNINGLKIWQEEVTRIINYNVERECNGFLRNKVHDWESSFQSRYVPIPHYAPTDSVSENFIGRLAREILRITDPKSTIYIAQTSTWYDIKSQKMIANKQLISLIASGIEVTGLVGLDRLFSFMIITNLKNILGILENKDKRNASWHNILTLISSEIKSTNTLSNPSKFYQNSISRSSKLFGPLLDHILAVGQLQILRKLIAFHLNTRSKFDAKYLESSLNSMNKALLIEMSNPNESKISEELLLKLSQYFDYSGLNNPFYKVYVTGKCNEEYAMNLFVFTISYLPRMFLYGCSNVLKRNFEFDGAIFVNGLHTLLKQFHTDLNKKFIYHLCQYVLQLTKQAIT</sequence>
    <xref id="XP_017775271.1" name="XP_017775271.1 PREDICTED: WASH complex subunit strumpellin isoform X2 [Nicrophorus vespilloides]"/>
    <matches>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="486" end="506">
            <location-fragments>
              <coils-location-fragment start="486" end="506" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="62" end="82">
            <location-fragments>
              <coils-location-fragment start="62" end="82" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="421" end="441">
            <location-fragments>
              <coils-location-fragment start="421" end="441" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <hmmer3-match evalue="0.0" score="1458.1">
        <signature ac="PF10266" desc="Hereditary spastic paraplegia protein strumpellin" name="Strumpellin">
          <entry ac="IPR019393" desc="WASH complex, subunit strumpellin" name="WASH_strumpellin" type="FAMILY">
            <go-xref category="CELLULAR_COMPONENT" db="GO" id="GO:0071203" name="WASH complex"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF10266</model-ac>
        <locations>
          <hmmer3-location env-end="1090" env-start="23" post-processed="true" score="1458.0" evalue="0.0" hmm-start="1" hmm-end="1085" hmm-length="1085" hmm-bounds="COMPLETE" start="23" end="1090">
            <location-fragments>
              <hmmer3-location-fragment start="23" end="1090" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <panther-match evalue="0.0" familyName="WASH COMPLEX SUBUNIT 5" score="1386.2">
        <signature ac="PTHR15691" name="WASH COMPLEX SUBUNIT 5">
          <entry ac="IPR019393" desc="WASH complex, subunit strumpellin" name="WASH_strumpellin" type="FAMILY">
            <go-xref category="CELLULAR_COMPONENT" db="GO" id="GO:0071203" name="WASH complex"/>
          </entry>
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR15691</model-ac>
        <locations>
          <panther-location env-start="2" env-end="1099" hmm-start="2" hmm-end="1097" hmm-length="1152" hmm-bounds="INCOMPLETE" start="3" end="1097">
            <location-fragments>
              <panther-location-fragment start="3" end="1097" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
    </matches>
  </protein>
  <protein>
    <sequence md5="4576f9873a808a22e73427e633860b87">MSENREVILADFQACTGIDDVARAIYILEENNWDFLNAVNKVMPQDLQSFQGNSRANAGSAPEVIEIPSSPVESATDMLSVGNNVPHNSRSMPILDNYSHSFSFPSTSTVNVNGARMIKFNVQYCDRVVTIEVPDTGTVADIKRLLNKELKVATCRQLLSGWARMPQYQNTPLSELSLPDMNALHLTVINNQDFSVDDTEVTERLKGNYILKIRDENADKMYSLNYPGTKTILDVKSDVYSLTNIHVRNQVWSGWPPNIDDNTMLALSGINFPEHDLTLRQIDSDDDEFEDASESFNVEDDCFMDHFSSKRVEPLIPKHVEDEIVGSISFSEQFTNRYGPIHPNFYQGTLEDAVREACNKPSKDRKLLGIYLHHDSSVLSNVFCTQLLGFESVMQLLERNFVLWGWDVTFETNRTRLQTSIMNTLGPMAASSLKNIPVDKLPAIFIIMKIRSSTDIYNIVYGNVGVNELLSSMIEAVEVFSEHQKVEMKEEQERAERELVKWEQDMAYNESLEADRAKEEAKRAQAEAENRERERVENEIAVETARREDHRLKVEQSLPEEPAPGTSNITKIRFRLPTGDNLERRFYINTPLKVLMDYCVVKGYPTEEYKVISSWPRRDLTLMDASKTLMELNLCPQETVILEER</sequence>
    <xref id="XP_017775062.1" name="XP_017775062.1 PREDICTED: FAS-associated factor 1 isoform X2 [Nicrophorus vespilloides]"/>
    <matches>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="507" end="553">
            <location-fragments>
              <coils-location-fragment start="507" end="553" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="485" end="505">
            <location-fragments>
              <coils-location-fragment start="485" end="505" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <hmmer2-match evalue="1.5E-30" score="117.5">
        <signature ac="SM00594" name="45neu3">
          <entry ac="IPR006577" desc="UAS" name="UAS" type="DOMAIN">
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00594</model-ac>
        <locations>
          <hmmer2-location score="117.5" evalue="1.5E-30" hmm-start="1" hmm-end="158" hmm-length="158" hmm-bounds="COMPLETE" start="329" end="474">
            <location-fragments>
              <hmmer2-location-fragment start="329" end="474" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer2-match evalue="3.3E-10" score="49.9">
        <signature ac="SM00166" name="ubx_3">
          <entry ac="IPR001012" desc="UBX domain" name="UBX_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00166</model-ac>
        <locations>
          <hmmer2-location score="49.9" evalue="3.3E-10" hmm-start="1" hmm-end="97" hmm-length="97" hmm-bounds="COMPLETE" start="562" end="644">
            <location-fragments>
              <hmmer2-location-fragment start="562" end="644" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer3-match evalue="1.2E-13" score="51.0">
        <signature ac="PF00789" desc="UBX domain" name="UBX">
          <entry ac="IPR001012" desc="UBX domain" name="UBX_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF00789</model-ac>
        <locations>
          <hmmer3-location env-end="644" env-start="566" post-processed="true" score="49.8" evalue="3.0E-13" hmm-start="5" hmm-end="81" hmm-length="81" hmm-bounds="C_TERMINAL_COMPLETE" start="568" end="644">
            <location-fragments>
              <hmmer3-location-fragment start="568" end="644" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="2.8E-7" score="30.3">
        <signature ac="PF14555" desc="UBA-like domain" name="UBA_4">
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF14555</model-ac>
        <locations>
          <hmmer3-location env-end="46" env-start="6" post-processed="true" score="28.8" evalue="8.0E-7" hmm-start="4" hmm-end="35" hmm-length="43" hmm-bounds="INCOMPLETE" start="9" end="41">
            <location-fragments>
              <hmmer3-location-fragment start="9" end="41" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="9.8E-32" score="110.8">
        <signature ac="G3DSA:3.10.20.90" name="">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2dzmA01</model-ac>
        <locations>
          <hmmer3-location env-end="186" env-start="116" post-processed="true" score="59.2" evalue="1.3E-15" hmm-start="1" hmm-end="71" hmm-length="72" hmm-bounds="COMPLETE" start="116" end="186">
            <location-fragments>
              <hmmer3-location-fragment start="116" end="186" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="279" env-start="210" post-processed="true" score="46.4" evalue="1.3E-11" hmm-start="3" hmm-end="64" hmm-length="72" hmm-bounds="COMPLETE" start="210" end="279">
            <location-fragments>
              <hmmer3-location-fragment start="210" end="279" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="5.9E-51" score="174.5">
        <signature ac="G3DSA:3.40.30.10" name="Glutaredoxin">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2ec4A00</model-ac>
        <locations>
          <hmmer3-location env-end="488" env-start="313" post-processed="true" score="173.7" evalue="1.0E-50" hmm-start="7" hmm-end="176" hmm-length="178" hmm-bounds="COMPLETE" start="313" end="488">
            <location-fragments>
              <hmmer3-location-fragment start="313" end="488" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.1E-21" score="78.0">
        <signature ac="G3DSA:1.10.8.10" name="">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3e21A00</model-ac>
        <locations>
          <hmmer3-location env-end="45" env-start="1" post-processed="true" score="76.8" evalue="2.7E-21" hmm-start="2" hmm-end="45" hmm-length="45" hmm-bounds="COMPLETE" start="1" end="45">
            <location-fragments>
              <hmmer3-location-fragment start="1" end="45" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.7E-23" score="84.3">
        <signature ac="G3DSA:3.10.20.90" name="">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3qq8B00</model-ac>
        <locations>
          <hmmer3-location env-end="645" env-start="565" post-processed="true" score="83.1" evalue="4.1E-23" hmm-start="6" hmm-end="83" hmm-length="85" hmm-bounds="COMPLETE" start="565" end="645">
            <location-fragments>
              <hmmer3-location-fragment start="565" end="645" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <panther-match evalue="4.0E-144" familyName="FAS-ASSOCIATED FACTOR 1" score="493.6">
        <signature ac="PTHR23322" name="FAS-ASSOCIATED PROTEIN">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR23322</model-ac>
        <locations>
          <panther-location env-start="1" env-end="644" hmm-start="4" hmm-end="607" hmm-length="607" hmm-bounds="C_TERMINAL_COMPLETE" start="4" end="644">
            <location-fragments>
              <panther-location-fragment start="4" end="644" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <panther-match evalue="4.0E-144" familyName="FAS-ASSOCIATED FACTOR 1" score="493.6">
        <signature ac="PTHR23322:SF56" name="FAS-ASSOCIATED FACTOR 1">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR23322:SF56</model-ac>
        <locations>
          <panther-location env-start="1" env-end="644" hmm-start="4" hmm-end="607" hmm-length="607" hmm-bounds="C_TERMINAL_COMPLETE" start="4" end="644">
            <location-fragments>
              <panther-location-fragment start="4" end="644" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <profilescan-match>
        <signature ac="PS50033" desc="UBX domain profile." name="UBX">
          <entry ac="IPR001012" desc="UBX domain" name="UBX_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
          </entry>
          <signature-library-release library="PROSITE_PROFILES" version="2021_01"/>
        </signature>
        <model-ac>PS50033</model-ac>
        <locations>
          <profilescan-location score="19.003719" start="565" end="642">
            <location-fragments>
              <profilescan-location-fragment start="565" end="642" dc-status="CONTINUOUS"/>
            </location-fragments>
            <alignment>GTSNITKIRFRLPTGDNLERRFYINTPLKVLMDYCVV--KGYPTEEYKVISSWPRRDLTLMDASKTLMELNLCPQETVIL</alignment>
          </profilescan-location>
        </locations>
      </profilescan-match>
      <rpsblast-match>
        <signature ac="cd01771" desc="UBX_UBXN3A" name="UBX_UBXN3A">
          <entry ac="IPR033043" desc="FAS-associated factor 1-like, UBX domain" name="FAF1-like_UBX" type="DOMAIN"/>
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd01771</model-ac>
        <locations>
          <rpsblast-location evalue="2.33823E-38" score="134.277" start="566" end="645">
            <location-fragments>
              <rpsblast-location-fragment start="566" end="645" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites>
              <rpsblast-site description="key conserved lysines" numLocations="3">
                <site-locations>
                  <site-location residue="K" start="602" end="602"/>
                  <site-location residue="R" start="575" end="575"/>
                  <site-location residue="R" start="618" end="618"/>
                </site-locations>
              </rpsblast-site>
              <rpsblast-site description="UBX-p97 interaction site" numLocations="7">
                <site-locations>
                  <site-location residue="E" start="638" end="638"/>
                  <site-location residue="W" start="615" end="615"/>
                  <site-location residue="K" start="571" end="571"/>
                  <site-location residue="T" start="639" end="639"/>
                  <site-location residue="R" start="575" end="575"/>
                  <site-location residue="L" start="582" end="582"/>
                  <site-location residue="R" start="573" end="573"/>
                </site-locations>
              </rpsblast-site>
            </sites>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <rpsblast-match>
        <signature ac="cd14413" desc="UBA_FAF1" name="UBA_FAF1">
          <entry ac="IPR044541" desc="FAF1, UBA-like domain" name="FAF1_UBA" type="DOMAIN"/>
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd14413</model-ac>
        <locations>
          <rpsblast-location evalue="2.04915E-11" score="56.9608" start="12" end="44">
            <location-fragments>
              <rpsblast-location-fragment start="12" end="44" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites/>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <rpsblast-match>
        <signature ac="cd17130" desc="Ubl2_FAF1" name="Ubl2_FAF1">
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd17130</model-ac>
        <locations>
          <rpsblast-location evalue="2.88057E-31" score="114.34" start="208" end="280">
            <location-fragments>
              <rpsblast-location-fragment start="208" end="280" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites/>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <superfamilyhmmer3-match evalue="2.83E-26">
        <signature ac="SSF54236" name="Ubiquitin-like">
          <entry ac="IPR029071" desc="Ubiquitin-like domain superfamily" name="Ubiquitin-like_domsf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CFA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SPO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-GGA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SPO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DRE-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-GGA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-HSA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-CEL-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-RNO-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-CFA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-BTA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-XTR-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-CFA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DDI-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-HSA-6803211" name="TP53 Regulates Transcription of Death Receptors and Ligands"/>
            <pathway-xref db="Reactome" id="R-CFA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-SPO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-139915" name="Activation of PUMA and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-XTR-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CEL-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SSC-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-SSC-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-SCE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-SSC-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-CEL-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-GGA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-DME-216167" name="Nuclear CI is degraded"/>
            <pathway-xref db="Reactome" id="R-BTA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6598" name="sciadonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-CFA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SSC-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-BTA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9694493" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5603027" name="IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SSC-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-HSA-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-CFA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SSC-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-BTA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-SSC-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-BTA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-SPO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7724" name="icosapentaenoate biosynthesis III (8-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7619" name="juniperonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-5358752" name="T41 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-SSC-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5362768" name="Hh mutants are degraded by ERAD"/>
            <pathway-xref db="Reactome" id="R-HSA-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-BTA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-BTA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-9613829" name="Chaperone Mediated Autophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-GGA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-CFA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-XTR-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-SSC-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-GGA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-CFA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SSC-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5080" name="very long chain fatty acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SSC-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-DME-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-GGA-351465" name="Fanconi Anemia Pathway in DNA repair"/>
            <pathway-xref db="Reactome" id="R-CFA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-CEL-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SSC-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-BTA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-433822" name="NFkB and MAPK activation mediated by TRAF6"/>
            <pathway-xref db="Reactome" id="R-SCE-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7036" name="very long chain fatty acid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9683610" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-SSC-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SCE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-SSC-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-DDI-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-6433" name="hydroxylated fatty acid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SSC-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227882" name="TRAF mediated activation of IRF"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-BTA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-SSC-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-BTA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-XTR-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-SPO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-SSC-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CFA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SSC-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DME-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-BTA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-SSC-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-6803204" name="TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"/>
            <pathway-xref db="Reactome" id="R-HSA-167287" name="HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SSC-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2691232" name="Constitutive Signaling by NOTCH1 HD Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SCE-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9031525" name="NR1H2 &amp; NR1H3 regulate gene expression to limit cholesterol uptake"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5334118" name="DNA methylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="MetaCyc" id="PWY-8041" name="ultra-long-chain fatty acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-GGA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5368598" name="Negative regulation of TCF-dependent signaling by DVL-interacting proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2408557" name="Selenocysteine synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-BTA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-SSC-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DME-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SPO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SSC-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-CEL-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-RNO-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-GGA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-HSA-175474" name="Assembly Of The HIV Virion"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-GGA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DME-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DME-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-CFA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-RNO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-GGA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-BTA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SPO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CFA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-BTA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-SPO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DRE-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-GGA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-GGA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CFA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-GGA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-192823" name="Viral mRNA Translation"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CFA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DME-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5358747" name="S33 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SSC-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-DME-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SSC-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-BTA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-XTR-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-GGA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-XTR-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-RNO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-CEL-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-GGA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-XTR-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="Reactome" id="R-GGA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358751" name="S45 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-BTA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-9683683" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-BTA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SSC-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SSC-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-RNO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-CEL-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-350480" name="Activation of non-muscle Myosin II"/>
            <pathway-xref db="Reactome" id="R-GGA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-SPO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-SCE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-GGA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SCE-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-RNO-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DME-350368" name="Activation of RHO1 by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-CFA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-GGA-353299" name="RAD18 and ubiquitinated PCNA-mediated recruitment of translesion polymerases"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-BTA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227888" name="Negative Regulation of MDA5 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9633012" name="Response of EIF2AK4 (GCN2) to amino acid deficiency"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SPO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DME-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-DME-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-BTA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9694631" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-380994" name="ATF4 activates genes in response to endoplasmic reticulum stress"/>
            <pathway-xref db="Reactome" id="R-SPO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CEL-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-CFA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-DME-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-DRE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DDI-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-BTA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-RNO-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DDI-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-GGA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SSC-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-GGA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-SPO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-CEL-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-8931987" name="RUNX1 regulates estrogen receptor mediated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SCE-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-6803205" name="TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"/>
            <pathway-xref db="Reactome" id="R-SSC-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CFA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5467337" name="APC truncation mutants have impaired AXIN binding"/>
            <pathway-xref db="Reactome" id="R-SSC-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-5467348" name="Truncations of AMER1 destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DRE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6351" name="D-myo-inositol (1,4,5)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-CEL-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-CFA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SCE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-5602636" name="IKBKB deficiency causes SCID"/>
            <pathway-xref db="Reactome" id="R-CFA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-209447" name="Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY"/>
            <pathway-xref db="Reactome" id="R-MMU-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-GGA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DDI-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-GGA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-CEL-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-MMU-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-69541" name="Stabilization of p53"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SSC-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-350411" name="Formation and asymmetric localisation of transmembrane complexes"/>
            <pathway-xref db="Reactome" id="R-GGA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-BTA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-RNO-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-BTA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-BTA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-BTA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5467340" name="AXIN missense mutants destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-167238" name="Pausing and recovery of Tat-mediated HIV elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-437980" name="Activated TAK1 mediates p38 MAP kinase phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SCE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-SSC-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-HSA-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-BTA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-GGA-437986" name="Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-8939256" name="RUNX1 regulates transcription of genes involved in WNT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SSC-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-SCE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-GGA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7035" name="(9Z)-tricosene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-SSC-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-BTA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DME-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-DME-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-BTA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-433871" name="TRAF6 mediated induction of proinflammatory cytokines"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CFA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DRE-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-538864" name="Degradation of CRY"/>
            <pathway-xref db="Reactome" id="R-CFA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DME-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-BTA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DRE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-573298" name="NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-451806" name="Phosphorylation-independent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-CFA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DME-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CFA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9013973" name="TICAM1-dependent activation of IRF3/IRF7"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-162588" name="Budding and maturation of HIV virion"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SSC-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-DDI-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-168927" name="TICAM1, RIP1-mediated IKK complex recruitment"/>
            <pathway-xref db="Reactome" id="R-DDI-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5678895" name="Defective CFTR causes cystic fibrosis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CFA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-DME-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-GGA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SSC-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7725" name="arachidonate biosynthesis V (8-detaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358749" name="S37 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-CEL-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-RNO-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CFA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-167243" name="Tat-mediated HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SCE-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-BTA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CFA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-SSC-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-MMU-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-CFA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9014325" name="TICAM1,TRAF6-dependent induction of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-8876493" name="InlA-mediated entry of Listeria monocytogenes into host cells"/>
            <pathway-xref db="Reactome" id="R-MMU-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DRE-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-SPO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-CFA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-DDI-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-4411364" name="Binding of TCF/LEF:CTNNB1 to target gene promoters"/>
            <pathway-xref db="Reactome" id="R-RNO-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-SCE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-350369" name="Negative feedback loop regulates asymmetric localisation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-CFA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-XTR-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-HSA-975110" name="TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SPO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-CFA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SCE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CFA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-GGA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SCE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-BTA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-DRE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-SCE-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-GGA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SSC-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-HSA-167290" name="Pausing and recovery of HIV elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CFA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-GGA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SSC-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CFA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-389977" name="Post-chaperonin tubulin folding pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CFA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-CFA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-180585" name="Vif-mediated degradation of APOBEC3G"/>
            <pathway-xref db="Reactome" id="R-RNO-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DME-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CFA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-174490" name="Membrane binding and targetting of GAG proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-CFA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-BTA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-CEL-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-DRE-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-GGA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9615710" name="Late endosomal microautophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-CFA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CFA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-933543" name="NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"/>
            <pathway-xref db="Reactome" id="R-MMU-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DRE-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-BTA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-SPO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-432395" name="Degradation of TIM"/>
            <pathway-xref db="Reactome" id="R-GGA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SSC-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-BTA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-CFA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-MMU-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-BTA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-BTA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-BTA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DDI-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-BTA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5339716" name="Signaling by GSK3beta mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-SSC-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DME-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-SCE-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="MetaCyc" id="PWY-6367" name="D-myo-inositol-5-phosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CFA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-SSC-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-RNO-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0050607</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="124" start="528" end="644">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="528" end="644" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
      <superfamilyhmmer3-match evalue="2.0E-7">
        <signature ac="SSF54236" name="Ubiquitin-like">
          <entry ac="IPR029071" desc="Ubiquitin-like domain superfamily" name="Ubiquitin-like_domsf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CFA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SPO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-GGA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SPO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DRE-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-GGA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-HSA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-CEL-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-RNO-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-CFA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-BTA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-XTR-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-CFA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DDI-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-HSA-6803211" name="TP53 Regulates Transcription of Death Receptors and Ligands"/>
            <pathway-xref db="Reactome" id="R-CFA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-SPO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-139915" name="Activation of PUMA and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-XTR-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CEL-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SSC-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-SSC-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-SCE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-SSC-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-CEL-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-GGA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-DME-216167" name="Nuclear CI is degraded"/>
            <pathway-xref db="Reactome" id="R-BTA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6598" name="sciadonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-CFA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SSC-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-BTA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9694493" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5603027" name="IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SSC-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-HSA-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-CFA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SSC-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-BTA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-SSC-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-BTA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-SPO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7724" name="icosapentaenoate biosynthesis III (8-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7619" name="juniperonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-5358752" name="T41 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-SSC-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5362768" name="Hh mutants are degraded by ERAD"/>
            <pathway-xref db="Reactome" id="R-HSA-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-BTA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-BTA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-9613829" name="Chaperone Mediated Autophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-GGA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-CFA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-XTR-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-SSC-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-GGA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-CFA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SSC-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5080" name="very long chain fatty acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SSC-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-DME-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-GGA-351465" name="Fanconi Anemia Pathway in DNA repair"/>
            <pathway-xref db="Reactome" id="R-CFA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-CEL-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SSC-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-BTA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-433822" name="NFkB and MAPK activation mediated by TRAF6"/>
            <pathway-xref db="Reactome" id="R-SCE-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7036" name="very long chain fatty acid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9683610" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-SSC-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SCE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-SSC-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-DDI-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-6433" name="hydroxylated fatty acid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SSC-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227882" name="TRAF mediated activation of IRF"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-BTA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-SSC-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-BTA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-XTR-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-SPO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-SSC-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CFA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SSC-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DME-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-BTA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-SSC-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-6803204" name="TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"/>
            <pathway-xref db="Reactome" id="R-HSA-167287" name="HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SSC-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2691232" name="Constitutive Signaling by NOTCH1 HD Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SCE-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9031525" name="NR1H2 &amp; NR1H3 regulate gene expression to limit cholesterol uptake"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5334118" name="DNA methylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="MetaCyc" id="PWY-8041" name="ultra-long-chain fatty acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-GGA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5368598" name="Negative regulation of TCF-dependent signaling by DVL-interacting proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2408557" name="Selenocysteine synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-BTA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-SSC-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DME-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SPO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SSC-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-CEL-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-RNO-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-GGA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-HSA-175474" name="Assembly Of The HIV Virion"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-GGA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DME-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DME-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-CFA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-RNO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-GGA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-BTA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SPO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CFA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-BTA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-SPO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DRE-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-GGA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-GGA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CFA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-GGA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-192823" name="Viral mRNA Translation"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CFA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DME-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5358747" name="S33 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SSC-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-DME-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SSC-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-BTA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-XTR-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-GGA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-XTR-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-RNO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-CEL-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-GGA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-XTR-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="Reactome" id="R-GGA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358751" name="S45 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-BTA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-9683683" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-BTA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SSC-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SSC-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-RNO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-CEL-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-350480" name="Activation of non-muscle Myosin II"/>
            <pathway-xref db="Reactome" id="R-GGA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-SPO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-SCE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-GGA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SCE-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-RNO-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DME-350368" name="Activation of RHO1 by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-CFA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-GGA-353299" name="RAD18 and ubiquitinated PCNA-mediated recruitment of translesion polymerases"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-BTA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227888" name="Negative Regulation of MDA5 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9633012" name="Response of EIF2AK4 (GCN2) to amino acid deficiency"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SPO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DME-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-DME-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-BTA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9694631" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-380994" name="ATF4 activates genes in response to endoplasmic reticulum stress"/>
            <pathway-xref db="Reactome" id="R-SPO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CEL-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-CFA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-DME-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-DRE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DDI-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-BTA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-RNO-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DDI-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-GGA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SSC-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-GGA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-SPO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-CEL-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-8931987" name="RUNX1 regulates estrogen receptor mediated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SCE-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-6803205" name="TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"/>
            <pathway-xref db="Reactome" id="R-SSC-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CFA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5467337" name="APC truncation mutants have impaired AXIN binding"/>
            <pathway-xref db="Reactome" id="R-SSC-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-5467348" name="Truncations of AMER1 destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DRE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6351" name="D-myo-inositol (1,4,5)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-CEL-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-CFA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SCE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-5602636" name="IKBKB deficiency causes SCID"/>
            <pathway-xref db="Reactome" id="R-CFA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-209447" name="Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY"/>
            <pathway-xref db="Reactome" id="R-MMU-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-GGA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DDI-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-GGA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-CEL-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-MMU-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-69541" name="Stabilization of p53"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SSC-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-350411" name="Formation and asymmetric localisation of transmembrane complexes"/>
            <pathway-xref db="Reactome" id="R-GGA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-BTA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-RNO-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-BTA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-BTA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-BTA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5467340" name="AXIN missense mutants destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-167238" name="Pausing and recovery of Tat-mediated HIV elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-437980" name="Activated TAK1 mediates p38 MAP kinase phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SCE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-SSC-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-HSA-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-BTA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-GGA-437986" name="Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-8939256" name="RUNX1 regulates transcription of genes involved in WNT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SSC-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-SCE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-GGA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7035" name="(9Z)-tricosene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-SSC-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-BTA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DME-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-DME-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-BTA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-433871" name="TRAF6 mediated induction of proinflammatory cytokines"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CFA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DRE-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-538864" name="Degradation of CRY"/>
            <pathway-xref db="Reactome" id="R-CFA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DME-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-BTA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DRE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-573298" name="NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-451806" name="Phosphorylation-independent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-CFA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DME-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CFA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9013973" name="TICAM1-dependent activation of IRF3/IRF7"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-162588" name="Budding and maturation of HIV virion"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SSC-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-DDI-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-168927" name="TICAM1, RIP1-mediated IKK complex recruitment"/>
            <pathway-xref db="Reactome" id="R-DDI-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5678895" name="Defective CFTR causes cystic fibrosis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CFA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-DME-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-GGA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SSC-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7725" name="arachidonate biosynthesis V (8-detaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358749" name="S37 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-CEL-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-RNO-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CFA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-167243" name="Tat-mediated HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SCE-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-BTA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CFA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-SSC-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-MMU-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-CFA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9014325" name="TICAM1,TRAF6-dependent induction of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-8876493" name="InlA-mediated entry of Listeria monocytogenes into host cells"/>
            <pathway-xref db="Reactome" id="R-MMU-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DRE-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-SPO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-CFA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-DDI-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-4411364" name="Binding of TCF/LEF:CTNNB1 to target gene promoters"/>
            <pathway-xref db="Reactome" id="R-RNO-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-SCE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-350369" name="Negative feedback loop regulates asymmetric localisation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-CFA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-XTR-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-HSA-975110" name="TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SPO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-CFA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SCE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CFA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-GGA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SCE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-BTA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-DRE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-SCE-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-GGA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SSC-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-HSA-167290" name="Pausing and recovery of HIV elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CFA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-GGA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SSC-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CFA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-389977" name="Post-chaperonin tubulin folding pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CFA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-CFA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-180585" name="Vif-mediated degradation of APOBEC3G"/>
            <pathway-xref db="Reactome" id="R-RNO-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DME-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CFA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-174490" name="Membrane binding and targetting of GAG proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-CFA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-BTA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-CEL-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-DRE-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-GGA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9615710" name="Late endosomal microautophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-CFA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CFA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-933543" name="NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"/>
            <pathway-xref db="Reactome" id="R-MMU-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DRE-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-BTA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-SPO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-432395" name="Degradation of TIM"/>
            <pathway-xref db="Reactome" id="R-GGA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SSC-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-BTA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-CFA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-MMU-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-BTA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-BTA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-BTA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DDI-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-BTA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5339716" name="Signaling by GSK3beta mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-SSC-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DME-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-SCE-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="MetaCyc" id="PWY-6367" name="D-myo-inositol-5-phosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CFA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-SSC-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-RNO-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0050086</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="95" start="107" end="187">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="107" end="187" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
      <superfamilyhmmer3-match evalue="7.95E-6">
        <signature ac="SSF54236" name="Ubiquitin-like">
          <entry ac="IPR029071" desc="Ubiquitin-like domain superfamily" name="Ubiquitin-like_domsf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CFA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-SCE-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SSC-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SPO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-156902" name="Peptide chain elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DRE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-GGA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-GGA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SPO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DDI-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-DRE-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-GGA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-HSA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-CEL-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-RNO-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-CFA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-BTA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-XTR-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-CFA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-GGA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DDI-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-HSA-6803211" name="TP53 Regulates Transcription of Death Receptors and Ligands"/>
            <pathway-xref db="Reactome" id="R-CFA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-SPO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-139915" name="Activation of PUMA and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-XTR-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DDI-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CEL-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-RNO-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-DME-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-SSC-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-SSC-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-SCE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-SSC-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-CEL-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-GGA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-DME-216167" name="Nuclear CI is degraded"/>
            <pathway-xref db="Reactome" id="R-BTA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6598" name="sciadonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-CFA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SSC-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-BTA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9694493" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5603027" name="IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SSC-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-DDI-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-9636383" name="Prevention of phagosomal-lysosomal fusion"/>
            <pathway-xref db="Reactome" id="R-DDI-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SSC-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-HSA-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-CFA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SSC-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-BTA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-SSC-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-BTA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-SPO-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7724" name="icosapentaenoate biosynthesis III (8-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7619" name="juniperonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-5358752" name="T41 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-SSC-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5362768" name="Hh mutants are degraded by ERAD"/>
            <pathway-xref db="Reactome" id="R-HSA-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-BTA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-BTA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-9613829" name="Chaperone Mediated Autophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-GGA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-CFA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-GGA-353303" name="Nucleotide Excision Repair"/>
            <pathway-xref db="Reactome" id="R-XTR-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-SSC-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-GGA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-CFA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SSC-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5080" name="very long chain fatty acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SSC-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DDI-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-DME-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-GGA-351465" name="Fanconi Anemia Pathway in DNA repair"/>
            <pathway-xref db="Reactome" id="R-CFA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-CEL-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-CEL-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-SSC-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-BTA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-433822" name="NFkB and MAPK activation mediated by TRAF6"/>
            <pathway-xref db="Reactome" id="R-SCE-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7036" name="very long chain fatty acid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9683610" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-SSC-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-SCE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-SSC-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-CEL-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-DDI-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="MetaCyc" id="PWY-6433" name="hydroxylated fatty acid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SSC-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227882" name="TRAF mediated activation of IRF"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-BTA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-SSC-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-BTA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-XTR-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-BTA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-SPO-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-SSC-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CFA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SSC-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SPO-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DME-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-RNO-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-DME-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-BTA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-SSC-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-6803204" name="TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"/>
            <pathway-xref db="Reactome" id="R-HSA-167287" name="HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SSC-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-CEL-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SCE-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2691232" name="Constitutive Signaling by NOTCH1 HD Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DDI-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SCE-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9031525" name="NR1H2 &amp; NR1H3 regulate gene expression to limit cholesterol uptake"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-CEL-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5334118" name="DNA methylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="MetaCyc" id="PWY-8041" name="ultra-long-chain fatty acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-SCE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-GGA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5368598" name="Negative regulation of TCF-dependent signaling by DVL-interacting proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2408557" name="Selenocysteine synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-BTA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-SSC-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DME-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SPO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-SSC-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-SSC-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-CEL-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-RNO-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-GGA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-CEL-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-HSA-175474" name="Assembly Of The HIV Virion"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-GGA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DME-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CEL-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-SSC-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DME-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-CFA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-SCE-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-RNO-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-GGA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-GGA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DDI-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-BTA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SPO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SSC-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-GGA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CFA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-CEL-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-BTA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-SPO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-BTA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-RNO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DRE-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-GGA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-GGA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SSC-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CFA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-GGA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-192823" name="Viral mRNA Translation"/>
            <pathway-xref db="Reactome" id="R-CEL-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-BTA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-BTA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SPO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CFA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DME-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5358747" name="S33 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-HSA-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-RNO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-MMU-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-SSC-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-CEL-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-DME-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SSC-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-BTA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-XTR-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-MMU-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CEL-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-GGA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-XTR-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-RNO-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-CEL-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-GGA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SPO-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-GGA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SPO-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-XTR-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="Reactome" id="R-GGA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358751" name="S45 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-BTA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-MMU-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-9683683" name="Maturation of protein E"/>
            <pathway-xref db="Reactome" id="R-SSC-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-BTA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SSC-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SSC-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-RNO-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-CEL-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-350480" name="Activation of non-muscle Myosin II"/>
            <pathway-xref db="Reactome" id="R-GGA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-CFA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DDI-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CEL-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-SPO-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-SCE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-BTA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-GGA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-GGA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-GGA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-RNO-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-CEL-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-SCE-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-RNO-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DME-350368" name="Activation of RHO1 by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-CFA-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-MMU-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-GGA-353299" name="RAD18 and ubiquitinated PCNA-mediated recruitment of translesion polymerases"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-DME-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-BTA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-DME-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1227888" name="Negative Regulation of MDA5 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9679504" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-GGA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CFA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9633012" name="Response of EIF2AK4 (GCN2) to amino acid deficiency"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-SPO-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-SSC-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-DME-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-209360" name="Ubiquitination and proteolysis of phosphorylated CI"/>
            <pathway-xref db="Reactome" id="R-DME-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-BTA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-DME-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9694631" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-RNO-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-380994" name="ATF4 activates genes in response to endoplasmic reticulum stress"/>
            <pathway-xref db="Reactome" id="R-SPO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-GGA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-CEL-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-CFA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-DME-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-DRE-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DDI-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-BTA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-RNO-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-CFA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-SSC-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-DDI-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-MMU-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-GGA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-GGA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SSC-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-GGA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-GGA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-SPO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-CEL-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-8931987" name="RUNX1 regulates estrogen receptor mediated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-SCE-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-SCE-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-DRE-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-6803205" name="TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"/>
            <pathway-xref db="Reactome" id="R-SSC-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-RNO-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-CFA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CFA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-HSA-5467337" name="APC truncation mutants have impaired AXIN binding"/>
            <pathway-xref db="Reactome" id="R-SSC-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-GGA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-HSA-5467348" name="Truncations of AMER1 destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SSC-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DRE-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CFA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6351" name="D-myo-inositol (1,4,5)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-RNO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-BTA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-BTA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-BTA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-CEL-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-CFA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-SCE-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-MMU-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-BTA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-5602636" name="IKBKB deficiency causes SCID"/>
            <pathway-xref db="Reactome" id="R-CFA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-DRE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SPO-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-GGA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-209447" name="Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY"/>
            <pathway-xref db="Reactome" id="R-MMU-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-GGA-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DDI-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-GGA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-GGA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-CEL-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-MMU-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-MMU-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-CFA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-DRE-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-69541" name="Stabilization of p53"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-SSC-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SSC-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DDI-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-DME-350411" name="Formation and asymmetric localisation of transmembrane complexes"/>
            <pathway-xref db="Reactome" id="R-GGA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-BTA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-RNO-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-BTA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3065678" name="SUMO is transferred from E1 to E2 (UBE2I, UBC9)"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-BTA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-BTA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5467340" name="AXIN missense mutants destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-167238" name="Pausing and recovery of Tat-mediated HIV elongation"/>
            <pathway-xref db="Reactome" id="R-BTA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-GGA-437980" name="Activated TAK1 mediates p38 MAP kinase phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-BTA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SCE-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-GGA-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-450728" name="Inhibition of actin polymerisation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-SSC-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-HSA-5693571" name="Nonhomologous End-Joining (NHEJ)"/>
            <pathway-xref db="Reactome" id="R-BTA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-DRE-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-SSC-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-GGA-437986" name="Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-8939256" name="RUNX1 regulates transcription of genes involved in WNT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SSC-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110312" name="Translesion synthesis by REV1"/>
            <pathway-xref db="Reactome" id="R-SSC-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-SCE-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-GGA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="MetaCyc" id="PWY-7035" name="(9Z)-tricosene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-SSC-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-BTA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-GGA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DME-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-DME-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-BTA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-433871" name="TRAF6 mediated induction of proinflammatory cytokines"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-CFA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-DRE-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-538864" name="Degradation of CRY"/>
            <pathway-xref db="Reactome" id="R-CFA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-GGA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-DME-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-BTA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-DDI-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-DRE-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-CEL-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CFA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-573298" name="NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-451806" name="Phosphorylation-independent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SSC-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-CFA-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-DME-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CFA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9013973" name="TICAM1-dependent activation of IRF3/IRF7"/>
            <pathway-xref db="Reactome" id="R-DDI-72702" name="Ribosomal scanning and start codon recognition"/>
            <pathway-xref db="Reactome" id="R-HSA-4608870" name="Asymmetric localization of PCP proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-162588" name="Budding and maturation of HIV virion"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SSC-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-DDI-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-SSC-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-DDI-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-168927" name="TICAM1, RIP1-mediated IKK complex recruitment"/>
            <pathway-xref db="Reactome" id="R-DDI-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5678895" name="Defective CFTR causes cystic fibrosis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-SCE-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-DME-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CFA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CFA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-DME-174154" name="APC/C:Cdc20 mediated degradation of Securin"/>
            <pathway-xref db="Reactome" id="R-GGA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-MMU-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-DME-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-SSC-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-4090294" name="SUMOylation of intracellular receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-CFA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7725" name="arachidonate biosynthesis V (8-detaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5358749" name="S37 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-CEL-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-RNO-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-CFA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-SCE-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-167243" name="Tat-mediated HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-SCE-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-GGA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SCE-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-BTA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-72649" name="Translation initiation complex formation"/>
            <pathway-xref db="Reactome" id="R-CFA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5655862" name="Translesion synthesis by POLK"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-SSC-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SSC-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-GGA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-MMU-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-CFA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-SSC-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9014325" name="TICAM1,TRAF6-dependent induction of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-8876493" name="InlA-mediated entry of Listeria monocytogenes into host cells"/>
            <pathway-xref db="Reactome" id="R-MMU-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DRE-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-SPO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-MMU-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-CFA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-DDI-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-4411364" name="Binding of TCF/LEF:CTNNB1 to target gene promoters"/>
            <pathway-xref db="Reactome" id="R-RNO-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-4641258" name="Degradation of DVL"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-SCE-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-350369" name="Negative feedback loop regulates asymmetric localisation"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-CFA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-CEL-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-XTR-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-HSA-975110" name="TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SPO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-HSA-72764" name="Eukaryotic Translation Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-CFA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SCE-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-CFA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-GGA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SCE-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-GGA-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-BTA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-DRE-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-SCE-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-RNO-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-GGA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-CFA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-SSC-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-349425" name="Autodegradation of the E3 ubiquitin ligase COP1"/>
            <pathway-xref db="Reactome" id="R-HSA-167290" name="Pausing and recovery of HIV elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CFA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-CEL-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CEL-110314" name="Recognition of DNA damage by PCNA-containing replication complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-GGA-5689877" name="Josephin domain DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CEL-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-SSC-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-SSC-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CFA-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-389977" name="Post-chaperonin tubulin folding pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-SCE-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-SSC-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5685942" name="HDR through Homologous Recombination (HRR)"/>
            <pathway-xref db="Reactome" id="R-HSA-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-CFA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-CFA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-CFA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-GGA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-5656121" name="Translesion synthesis by POLI"/>
            <pathway-xref db="Reactome" id="R-HSA-180585" name="Vif-mediated degradation of APOBEC3G"/>
            <pathway-xref db="Reactome" id="R-RNO-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-MMU-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DME-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SSC-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CFA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-CFA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-CEL-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-SSC-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-174490" name="Membrane binding and targetting of GAG proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-HSA-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-CFA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-CFA-1234176" name="Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"/>
            <pathway-xref db="Reactome" id="R-BTA-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-DDI-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-GGA-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-CEL-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-BTA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866904" name="Negative regulation of activity of TFAP2 (AP-2) family transcription factors"/>
            <pathway-xref db="Reactome" id="R-CFA-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-DRE-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DDI-975956" name="Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-GGA-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9615710" name="Late endosomal microautophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SCE-9646399" name="Aggrephagy"/>
            <pathway-xref db="Reactome" id="R-CFA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-CFA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-4655427" name="SUMOylation of DNA methylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5696397" name="Gap-filling DNA repair synthesis and ligation in GG-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-GGA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-RNO-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-RNO-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-HSA-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-196791" name="Vitamin D (calciferol) metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9615933" name="Postmitotic nuclear pore complex (NPC) reformation"/>
            <pathway-xref db="Reactome" id="R-CFA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-933543" name="NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10"/>
            <pathway-xref db="Reactome" id="R-MMU-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-RNO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-382556" name="ABC-family proteins mediated transport"/>
            <pathway-xref db="Reactome" id="R-DRE-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-72689" name="Formation of a pool of free 40S subunits"/>
            <pathway-xref db="Reactome" id="R-BTA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CFA-205043" name="NRIF signals cell death from the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-75876" name="Synthesis of very long-chain fatty acyl-CoAs"/>
            <pathway-xref db="Reactome" id="R-SPO-3108232" name="SUMO E3 ligases SUMOylate target proteins"/>
            <pathway-xref db="Reactome" id="R-DME-432395" name="Degradation of TIM"/>
            <pathway-xref db="Reactome" id="R-GGA-4641257" name="Degradation of AXIN"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-174084" name="Autodegradation of Cdh1 by Cdh1:APC/C"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-3065676" name="SUMO is conjugated to E1 (UBA2:SAE1)"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-RNO-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SSC-156827" name="L13a-mediated translational silencing of Ceruloplasmin expression"/>
            <pathway-xref db="Reactome" id="R-RNO-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-BTA-4641263" name="Regulation of FZD by ubiquitination"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-DME-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-GGA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-CFA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DME-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-RNO-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-MMU-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-DDI-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-901032" name="ER Quality Control Compartment (ERQC)"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-BTA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-450408" name="AUF1 (hnRNP D0) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-BTA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-174113" name="SCF-beta-TrCP mediated degradation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-BTA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DDI-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-BTA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-68827" name="CDT1 association with the CDC6:ORC:origin complex"/>
            <pathway-xref db="Reactome" id="R-CFA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-SSC-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5339716" name="Signaling by GSK3beta mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-72695" name="Formation of the ternary complex, and subsequently, the 43S complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-SSC-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1799339" name="SRP-dependent cotranslational protein targeting to membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-110320" name="Translesion Synthesis by POLH"/>
            <pathway-xref db="Reactome" id="R-DME-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-6783310" name="Fanconi Anemia Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CFA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-5656169" name="Termination of translesion DNA synthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-SSC-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-SCE-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-SSC-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3065679" name="SUMO is proteolytically processed"/>
            <pathway-xref db="Reactome" id="R-MMU-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-69481" name="G2/M Checkpoints"/>
            <pathway-xref db="MetaCyc" id="PWY-6367" name="D-myo-inositol-5-phosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8948747" name="Regulation of PTEN localization"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-CFA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-72706" name="GTP hydrolysis and joining of the 60S ribosomal subunit"/>
            <pathway-xref db="Reactome" id="R-RNO-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-SPO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-SSC-9708530" name="Regulation of BACH1 activity"/>
            <pathway-xref db="Reactome" id="R-RNO-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5696394" name="DNA Damage Recognition in GG-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-8866652" name="Synthesis of active ubiquitin: roles of E1 and E2 enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0050086</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="95" start="196" end="270">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="196" end="270" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
      <superfamilyhmmer3-match evalue="1.19E-8">
        <signature ac="SSF52833" name="Thioredoxin-like">
          <entry ac="IPR036249" desc="Thioredoxin-like superfamily" name="Thioredoxin-like_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="MetaCyc" id="PWY-8238" name="24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)"/>
            <pathway-xref db="Reactome" id="R-RNO-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="Reactome" id="R-HSA-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-8111" name="carbaryl degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7325" name="salvigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-5083" name="NAD(P)/NADPH interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5676934" name="Protein repair"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7629" name="yatein biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6973" name="dTDP-alpha-D-olivose, dTDP-alpha-D-oliose and dTDP-alpha-D-mycarose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="MetaCyc" id="PWY-7757" name="bisphenol A degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8100" name="crotonosine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7698" name="2,5-xylenol and 3,5-xylenol degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7631" name="arctigenin and isoarctigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-2261" name="ascorbate glutathione cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DRE-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7163" name="polymethylated kaempferol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8044" name="cyclohexane-1-carboxyl-CoA biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-611105" name="Respiratory electron transport"/>
            <pathway-xref db="Reactome" id="R-BTA-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6803" name="phosphatidylcholine acyl editing"/>
            <pathway-xref db="Reactome" id="R-SPO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5978" name="kanosamine biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6675" name="sulfur oxidation IV (intracellular sulfur)"/>
            <pathway-xref db="Reactome" id="R-SCE-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5826" name="hypoglycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-611105" name="Respiratory electron transport"/>
            <pathway-xref db="MetaCyc" id="PWY-5883" name="ephedrine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-156581" name="Methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-6526" name="limonene degradation III (to perillate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5421" name="dehydroabietic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-MMU-5578775" name="Ion homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-3061" name="menthol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="Reactome" id="R-HSA-5578775" name="Ion homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-9617629" name="Regulation of FOXO transcriptional activity by acetylation"/>
            <pathway-xref db="Reactome" id="R-SSC-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="Reactome" id="R-HSA-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7591" name="okenone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-SCE-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7605" name="roquefortine C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5802" name="alizarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7523" name="L-arginine degradation XII"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6887" name="kauralexin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8263" name="arsenate detoxification III"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5306" name="superpathway of thiosulfate metabolism (Desulfovibrio sulfodismutans)"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6511" name="3-methylarginine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8087" name="indole-3-acetate degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-6286" name="spheroidene and spheroidenone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8866423" name="VLDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-RNO-5676934" name="Protein repair"/>
            <pathway-xref db="MetaCyc" id="PWY-6739" name="pinitol biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-6681" name="neurosporaxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-6050" name="dimethyl sulfoxide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6932" name="selenate reduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7112" name="4-hydroxy-2-nonenal detoxification"/>
            <pathway-xref db="MetaCyc" id="PWY-5773" name="gossypol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5479" name="6-methoxypodophyllotoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7668" name="apicidin F biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5422" name="isopimaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6154" name="autoinducer AI-2 biosynthesis II (Vibrio)"/>
            <pathway-xref db="MetaCyc" id="PWY-7416" name="phospholipid remodeling (phosphatidylcholine, yeast)"/>
            <pathway-xref db="Reactome" id="R-RNO-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-8866423" name="VLDL assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-8866423" name="VLDL assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-350864" name="Regulation of thyroid hormone activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DRE-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4502" name="wighteone and luteone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-GGA-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7085" name="triethylamine degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7667" name="apicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-HSA-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6710" name="poly-hydroxy fatty acids biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7734" name="quinoxaline-2-carboxylate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7430" name="indole degradation to anthranil and anthranilate"/>
            <pathway-xref db="Reactome" id="R-MTU-936721" name="Cysteine synthesis from O-acetylserine"/>
            <pathway-xref db="Reactome" id="R-MMU-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="MetaCyc" id="PWY-2724" name="alkane oxidation"/>
            <pathway-xref db="MetaCyc" id="PWY-7285" name="methylwyosine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5815" name="rubber biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9694548" name="Maturation of spike protein"/>
            <pathway-xref db="Reactome" id="R-SCE-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-7923" name="archaeosine biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-DDI-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-611105" name="Respiratory electron transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7741" name="phthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-1614558" name="Degradation of cysteine and homocysteine"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7241" name="myo-inositol degradation II"/>
            <pathway-xref db="Reactome" id="R-RNO-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-5103" name="L-isoleucine biosynthesis III"/>
            <pathway-xref db="MetaCyc" id="PWY-2467" name="(+)-pisatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-CEL-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="MetaCyc" id="PWY-3781" name="aerobic respiration I (cytochrome c)"/>
            <pathway-xref db="Reactome" id="R-MMU-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-SPO-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6692" name="Fe(II) oxidation"/>
            <pathway-xref db="Reactome" id="R-CEL-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7626" name="bacilysin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7492" name="paspaline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-5368286" name="Mitochondrial translation initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-321" name="cutin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-SSC-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-1061" name="homogalacturonan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-4202" name="arsenic detoxification (mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7638" name="echinenone and zeaxanthin biosynthesis (Synechocystis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7513" name="flaviolin dimer and mompain biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7752" name="gadusol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="MetaCyc" id="PWY-8104" name="yangonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-350864" name="Regulation of thyroid hormone activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-RNO-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-156581" name="Methylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5871" name="ubiquinol-9 biosynthesis (late decarboxylation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7044" name="5-nitroanthranilate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-189483" name="Heme degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7011" name="2-isopropylphenol degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7895" name="ethionamide activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7498" name="phenylpropanoids methylation (ice plant)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7998" name="menaquinol-4 biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-5893" name="tridecaprenyl diphosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5729" name="vestitol and sativan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5816" name="all trans undecaprenyl diphosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8158" name="ibotenate and muscimol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4361" name="S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"/>
            <pathway-xref db="Reactome" id="R-SPO-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7717" name="3-hydroxy-4-methyl-anthranilate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5676934" name="Protein repair"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="MetaCyc" id="PWY-7655" name="dechlorogriseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7607" name="meleagrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7533" name="gliotoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6708" name="ubiquinol-8 biosynthesis (early decarboxylation)"/>
            <pathway-xref db="Reactome" id="R-DME-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SPO-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6503" name="superpathway of ergotamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5382" name="hydrogen oxidation II (aerobic, NAD)"/>
            <pathway-xref db="MetaCyc" id="PWY-4302" name="aerobic respiration III (alternative oxidase pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5995" name="linoleate biosynthesis I (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7765" name="3-hydroxy-4-methyl-anthranilate biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7155" name="7-dehydroporiferasterol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6261" name="thyroid hormone metabolism II (via conjugation and/or degradation)"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-1614558" name="Degradation of cysteine and homocysteine"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7739" name="aucuparin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5059" name="pinobanksin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5024" name="L-arginine degradation XI"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-350864" name="Regulation of thyroid hormone activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5368" name="dimorphecolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5336415" name="Uptake and function of diphtheria toxin"/>
            <pathway-xref db="MetaCyc" id="PWY-5979" name="3-amino-5-hydroxybenzoate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7977" name="L-methionine biosynthesis IV"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6835" name="6-gingerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-PFA-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7170" name="phytochromobilin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-RNO-156590" name="Glutathione conjugation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="Reactome" id="R-BTA-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-156590" name="Glutathione conjugation"/>
            <pathway-xref db="Reactome" id="R-MMU-156581" name="Methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7230" name="ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6197" name="chlorinated phenols degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-4621" name="arsenic detoxification (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7363" name="papaverine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-RNO-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7779" name="methyl tert-butyl ether degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603798" name="Class I peroxisomal membrane protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-6758" name="hydrogen production II"/>
            <pathway-xref db="MetaCyc" id="PWY-8076" name="8-O-methylated benzoxazinoid glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7534" name="gliotoxin inactivation"/>
            <pathway-xref db="MetaCyc" id="PWY-7043" name="11-cis-3-hydroxyretinal biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7580" name="phycoerythrobilin biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5418" name="phenol degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7079" name="geodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7643" name="coniferyl alcohol 9-methyl ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7439" name="dTDP-beta-L-evernitrose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7481" name="oryzalide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5336" name="carbon disulfide oxidation II (aerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-7906" name="rhizobitoxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7637" name="2,2'-dihydroxyketocarotenoids biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-156581" name="Methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-4681" name="kievitone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="Reactome" id="R-RNO-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="Reactome" id="R-CEL-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7775" name="propane degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="Reactome" id="R-PFA-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="MetaCyc" id="PWY-4181" name="glutathione amide metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2142688" name="Synthesis of 5-eicosatetraenoic acids"/>
            <pathway-xref db="Reactome" id="R-RNO-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-CEL-156581" name="Methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-4021" name="beta-alanine betaine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7618" name="ricinoleate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7649" name="3-hydroxy-L-homotyrosine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DRE-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-CEL-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8085" name="picolinate degradation"/>
            <pathway-xref db="Reactome" id="R-DDI-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6477" name="gibberellin inactivation II (methylation)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7703" name="2,4-xylenol degradation to protocatechuate"/>
            <pathway-xref db="Reactome" id="R-HSA-2408550" name="Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-6512" name="hydrogen oxidation III (anaerobic, NADP)"/>
            <pathway-xref db="MetaCyc" id="PWY-6370" name="ascorbate recycling (cytosolic)"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7812" name="tetracycline and oxytetracycline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5917" name="phycocyanobilin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-2142770" name="Synthesis of 15-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2142770" name="Synthesis of 15-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7440" name="dTDP-beta-L-4-epi-vancosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5427" name="naphthalene degradation (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7608" name="neoxaline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7154" name="ergosterol biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CEL-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-8951664" name="Neddylation"/>
            <pathway-xref db="MetaCyc" id="PWY-4081" name="glutathione-peroxide redox reactions"/>
            <pathway-xref db="Reactome" id="R-DME-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6978" name="plastoquinol-9 biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-6831" name="pyrrolnitrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7010" name="2-propylphenol degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9026762" name="Biosynthesis of maresin conjugates in tissue regeneration (MCTR)"/>
            <pathway-xref db="Reactome" id="R-MMU-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="MetaCyc" id="PWY-7417" name="phospholipid remodeling (phosphatidate, yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-8095" name="5-methoxy-6-methylbenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-6045" name="methylthiopropanonate degradation II (demethylation)"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="MetaCyc" id="PWY-8077" name="ginkgotoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7510" name="rhizocticin A and B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7648" name="3-hydroxy-4-methyl-proline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5882" name="epoxypseudoisoeugenol-2-methylbutanoate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7861" name="N-hydroxy-L-pipecolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7540" name="aflatrem biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7301" name="dTDP-4-O-demethyl-beta-L-noviose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-156590" name="Glutathione conjugation"/>
            <pathway-xref db="Reactome" id="R-DME-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-8103" name="kavain biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-5915" name="phycoerythrobilin biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SPO-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7483" name="elloramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7520" name="terrequinone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1222541" name="Cell redox homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-5414" name="palustric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7564" name="bacimethrin and bacimethrin pyrophosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8096" name="5-methoxybenzimidazole biosynthesis (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7603" name="stephacidin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6581" name="spirilloxanthin and 2,2'-diketo-spirilloxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5263617" name="Metabolism of ingested MeSeO2H into MeSeH"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2421" name="indole-3-acetate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7615" name="pterocarpan phytoalexins modification (maackiain, medicarpin, pisatin, phaseollin)"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6795" name="diacylglyceryl-N,N,N-trimethylhomoserine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-1381" name="fluorene degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-6765" name="hydrogen production IV"/>
            <pathway-xref db="Reactome" id="R-DRE-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-5305" name="bixin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="Reactome" id="R-BTA-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="MetaCyc" id="PWY-6153" name="autoinducer AI-2 biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-5676934" name="Protein repair"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6321" name="homotaurine degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7614" name="methiin metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1614558" name="Degradation of cysteine and homocysteine"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5857" name="ubiquinol-10 biosynthesis (early decarboxylation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7169" name="hyperxanthone E biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-HSA-6799198" name="Complex I biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-3542" name="choline biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7826" name="Amaryllidacea alkaloids biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7161" name="polymethylated quercetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-5706" name="alliin metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="Reactome" id="R-CEL-8963684" name="Tyrosine catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7462" name="3,3'-disulfanediyldipropannoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5412" name="levopimaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6659" name="fusicoccin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-CEL-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="MetaCyc" id="PWY-6421" name="arsenate detoxification IV (mycothiol)"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-HSA-917937" name="Iron uptake and transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1614558" name="Degradation of cysteine and homocysteine"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7304" name="3-amino-4,7-dihydroxy-coumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7729" name="5,6-dimethylbenzimidazole biosynthesis II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7733" name="3-hydroxyquinaldate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676934" name="Protein repair"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5870" name="ubiquinol-8 biosynthesis (late decarboxylation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2083" name="isoflavonoid biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7485" name="tetracenomycin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6223" name="gentisate degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5434" name="(3E)-4,8-dimethylnona-1,3,7-triene biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-SCE-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5748" name="gamma-coniciene and coniine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7783" name="plasmalogen degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7691" name="10,13-epoxy-11-methyl-octadecadienoate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8264" name="arsenate detoxification I"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="MetaCyc" id="PWY-5209" name="methyl-coenzyme M oxidation to CO2"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-DRE-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="MetaCyc" id="PWY-7814" name="dTDP-L-daunosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-RNO-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-SSC-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7104" name="dTDP-beta-L-megosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-695" name="abscisic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-532668" name="N-glycan trimming in the ER and Calnexin/Calreticulin cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6433" name="hydroxylated fatty acid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1222387" name="Tolerance of reactive oxygen produced by macrophages"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7937" name="fungal bioluminescence"/>
            <pathway-xref db="MetaCyc" id="PWY-6427" name="rot-2'-enonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7777" name="isoprene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5413" name="neoabietic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-5872" name="ubiquinol-10 biosynthesis (late decarboxylation)"/>
            <pathway-xref db="Reactome" id="R-BTA-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DDI-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6736" name="sulfur volatiles biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-5287" name="sanguinarine and macarpine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7578" name="phycoviolobilin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026762" name="Biosynthesis of maresin conjugates in tissue regeneration (MCTR)"/>
            <pathway-xref db="Reactome" id="R-HSA-1222538" name="Tolerance by Mtb to nitric oxide produced by macrophages"/>
            <pathway-xref db="Reactome" id="R-SSC-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5676934" name="Protein repair"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-BTA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7751" name="shinorine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9026762" name="Biosynthesis of maresin conjugates in tissue regeneration (MCTR)"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7949" name="diadinoxanthin and diatoxanthin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-8862803" name="Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7442" name="drosopterin and aurodrosopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6936" name="seleno-amino acid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-CEL-1614558" name="Degradation of cysteine and homocysteine"/>
            <pathway-xref db="MetaCyc" id="PWY-6495" name="ergotamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SPO-2142712" name="Synthesis of 12-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6262" name="demethylmenaquinol-8 biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-BTA-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-8083" name="domoic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7780" name="butane degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7298" name="nevadensin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5419276" name="Mitochondrial translation termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9026762" name="Biosynthesis of maresin conjugates in tissue regeneration (MCTR)"/>
            <pathway-xref db="Reactome" id="R-HSA-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-6409" name="pyoverdine I biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6976" name="dTDP-beta-L-mycarose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9018896" name="Biosynthesis of E-series 18(S)-resolvins"/>
            <pathway-xref db="Reactome" id="R-RNO-9033241" name="Peroxisomal protein import"/>
            <pathway-xref db="MetaCyc" id="PWY-7160" name="polymethylated myricetin biosynthesis (tomato)"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="MetaCyc" id="PWY-1186" name="L-homomethionine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7372" name="demethylmenaquinol-6 biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-SSC-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7749" name="(-)-4'-demethyl-epipodophyllotoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-6340" name="5,5'-dehydrodivanillate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963888" name="Chylomicron assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5665" name="vanillin biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-446203" name="Asparagine N-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7604" name="notoamide C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6260" name="thyroid hormone metabolism I (via deiodination)"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-CEL-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-204174" name="Regulation of pyruvate dehydrogenase (PDH) complex"/>
            <pathway-xref db="MetaCyc" id="PWY-5873" name="ubiquinol-7 biosynthesis (late decarboxylation)"/>
            <pathway-xref db="Reactome" id="R-DME-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-HSA-156842" name="Eukaryotic Translation Elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-3299685" name="Detoxification of Reactive Oxygen Species"/>
            <pathway-xref db="Reactome" id="R-HSA-1362409" name="Mitochondrial iron-sulfur cluster biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5765" name="1,3,5-trimethoxybenzene biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7650" name="echinocandin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9023661" name="Biosynthesis of E-series 18(R)-resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-6403" name="carrageenan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8031" name="epiberberine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-611105" name="Respiratory electron transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7009" name="2,2'-dihydroxybiphenyl degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-350864" name="Regulation of thyroid hormone activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8259" name="arsenic detoxification (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SSC-2142770" name="Synthesis of 15-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7517" name="brassicicene C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6552" name="caffeine degradation I (main, plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7573" name="GDP-mycosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4061" name="glutathione-mediated detoxification I"/>
            <pathway-xref db="Reactome" id="R-CEL-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-5855" name="ubiquinol-7 biosynthesis (early decarboxylation)"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-601" name="glucosinolate biosynthesis from tryptophan"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="Reactome" id="R-RNO-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-RNO-611105" name="Respiratory electron transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-189483" name="Heme degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7579" name="phycourobilin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-CEL-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-CEL-5389840" name="Mitochondrial translation elongation"/>
            <pathway-xref db="MetaCyc" id="PWY-7742" name="phenolphthiocerol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8172" name="10-methylstearate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6809" name="neoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="MetaCyc" id="PWY-1361" name="benzoyl-CoA degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7042" name="the visual cycle (insects)"/>
            <pathway-xref db="Reactome" id="R-SSC-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-156590" name="Glutathione conjugation"/>
            <pathway-xref db="MetaCyc" id="PWY-5360" name="superpathway of tetrathionate reduction (Salmonella typhimurium)"/>
            <pathway-xref db="MetaCyc" id="PWY-4161" name="superpathway of benzoxazinoid glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2142770" name="Synthesis of 15-eicosatetraenoic acid derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-196836" name="Vitamin C (ascorbate) metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-499943" name="Interconversion of nucleotide di- and triphosphates"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-8080" name="kainate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-5818" name="validamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7072" name="hopanoid biosynthesis (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7493" name="paxilline and diprenylpaxilline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5358346" name="Hedgehog ligand biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-156581" name="Methylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-6339" name="syringate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5856" name="ubiquinol-9 biosynthesis (early decarboxylation)"/>
            <pathway-xref db="Reactome" id="R-BTA-9020265" name="Biosynthesis of aspirin-triggered D-series resolvins"/>
            <pathway-xref db="MetaCyc" id="PWY-7701" name="4-hydroxy-4-methyl-L-glutamate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5817" name="dodecaprenyl diphosphate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7076" name="3,5-dimethoxytoluene biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-7175" name="nostoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-901042" name="Calnexin/calreticulin cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2162123" name="Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-GGA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-5301" name="ajmaline and sarpagine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8043" name="ophthalmate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-9018676" name="Biosynthesis of D-series resolvins"/>
            <pathway-xref db="Reactome" id="R-MMU-72165" name="mRNA Splicing - Minor Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7572" name="lolitrem B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2132295" name="MHC class II antigen presentation"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0053833</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="147" start="328" end="481">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="328" end="481" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
    </matches>
  </protein>
  <protein>
    <sequence md5="6742f3f9ca59ff0c5f6d668c028adaef">MNSSSVDANSRSAKLKFGIDRLLSSDKPSGKHHLHQHRHLEQYGYAKNSSSSTNVVSNSSVIVPCSDCVTSMFRCCSLSPSNHHHHHHHQDNGSAYPGMPPGSVYTMQPIRPFATRPTVRVPLPPSSPPTVTQPNGKRKRSWSRAVFSNLQRKGLERRFQLQKYITKPDRRQLAATLGLTDAQVKVWFQNRRMKWRHTKEAGKGSSDSPADSTQDELLIDVDTVSEND</sequence>
    <xref id="XP_017775509.1" name="XP_017775509.1 PREDICTED: homeobox protein H2.0 [Nicrophorus vespilloides]"/>
    <matches>
      <fingerprints-match evalue="1.2E-6" graphscan="III">
        <signature ac="PR00024" desc="Homeobox signature" name="HOMEOBOX">
          <entry ac="IPR020479" desc="Homeobox domain, metazoa" name="Homeobox_metazoa" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
          </entry>
          <signature-library-release library="PRINTS" version="42.0"/>
        </signature>
        <model-ac>PR00024</model-ac>
        <locations>
          <fingerprints-location motifNumber="2" pvalue="7.02E-5" score="57.86" start="177" end="187">
            <location-fragments>
              <fingerprints-location-fragment start="177" end="187" dc-status="CONTINUOUS"/>
            </location-fragments>
          </fingerprints-location>
          <fingerprints-location motifNumber="1" pvalue="5.07E-4" score="31.46" start="162" end="173">
            <location-fragments>
              <fingerprints-location-fragment start="162" end="173" dc-status="CONTINUOUS"/>
            </location-fragments>
          </fingerprints-location>
          <fingerprints-location motifNumber="3" pvalue="1.33E-5" score="77.58" start="187" end="196">
            <location-fragments>
              <fingerprints-location-fragment start="187" end="196" dc-status="CONTINUOUS"/>
            </location-fragments>
          </fingerprints-location>
        </locations>
      </fingerprints-match>
      <fingerprints-match evalue="1.2E-6" graphscan="II">
        <signature ac="PR00031" desc="Lambda-repressor HTH signature" name="HTHREPRESSR">
          <entry ac="IPR000047" desc="Helix-turn-helix motif" name="HTH_motif" type="CONSERVED_SITE">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
          </entry>
          <signature-library-release library="PRINTS" version="42.0"/>
        </signature>
        <model-ac>PR00031</model-ac>
        <locations>
          <fingerprints-location motifNumber="2" pvalue="2.03E-9" score="62.94" start="178" end="194">
            <location-fragments>
              <fingerprints-location-fragment start="178" end="194" dc-status="CONTINUOUS"/>
            </location-fragments>
          </fingerprints-location>
          <fingerprints-location motifNumber="1" pvalue="1.83E-4" score="48.93" start="169" end="178">
            <location-fragments>
              <fingerprints-location-fragment start="169" end="178" dc-status="CONTINUOUS"/>
            </location-fragments>
          </fingerprints-location>
        </locations>
      </fingerprints-match>
      <hmmer2-match evalue="1.5E-21" score="87.6">
        <signature ac="SM00389" name="HOX_1">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00389</model-ac>
        <locations>
          <hmmer2-location score="87.6" evalue="1.5E-21" hmm-start="1" hmm-end="63" hmm-length="63" hmm-bounds="COMPLETE" start="138" end="202">
            <location-fragments>
              <hmmer2-location-fragment start="138" end="202" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer3-match evalue="8.5E-20" score="70.4">
        <signature ac="PF00046" desc="Homeodomain" name="Homeodomain">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF00046</model-ac>
        <locations>
          <hmmer3-location env-end="197" env-start="141" post-processed="true" score="69.7" evalue="1.4E-19" hmm-start="3" hmm-end="57" hmm-length="57" hmm-bounds="C_TERMINAL_COMPLETE" start="143" end="197">
            <location-fragments>
              <hmmer3-location-fragment start="143" end="197" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="6.9E-23" score="82.6">
        <signature ac="G3DSA:1.10.10.60" name="">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1b72A00</model-ac>
        <locations>
          <hmmer3-location env-end="202" env-start="81" post-processed="true" score="82.1" evalue="1.1E-22" hmm-start="26" hmm-end="93" hmm-length="97" hmm-bounds="COMPLETE" start="81" end="202">
            <location-fragments>
              <hmmer3-location-fragment start="81" end="202" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="" start="193" end="228">
            <location-fragments>
              <mobidblite-location-fragment start="193" end="228" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <mobidblite-match>
        <signature ac="mobidb-lite" desc="consensus disorder prediction" name="disorder_prediction">
          <signature-library-release library="MOBIDB_LITE" version="2.0"/>
        </signature>
        <model-ac>mobidb-lite</model-ac>
        <locations>
          <mobidblite-location sequence-feature="Polar" start="205" end="220">
            <location-fragments>
              <mobidblite-location-fragment start="205" end="220" dc-status="CONTINUOUS"/>
            </location-fragments>
          </mobidblite-location>
        </locations>
      </mobidblite-match>
      <panther-match evalue="2.3E-55" familyName="H2.0-LIKE HOMEOBOX PROTEIN" score="200.5">
        <signature ac="PTHR46808" name="H2.0-LIKE HOMEOBOX PROTEIN">
          <signature-library-release library="PANTHER" version="15.0"/>
        </signature>
        <model-ac>PTHR46808</model-ac>
        <locations>
          <panther-location env-start="1" env-end="224" hmm-start="156" hmm-end="332" hmm-length="415" hmm-bounds="INCOMPLETE" start="8" end="207">
            <location-fragments>
              <panther-location-fragment start="8" end="207" dc-status="CONTINUOUS"/>
            </location-fragments>
          </panther-location>
        </locations>
      </panther-match>
      <patternscan-match>
        <signature ac="PS00027" desc="'Homeobox' domain signature." name="HOMEOBOX_1">
          <entry ac="IPR017970" desc="Homeobox, conserved site" name="Homeobox_CS" type="CONSERVED_SITE">
            <go-xref category="BIOLOGICAL_PROCESS" db="GO" id="GO:0006355" name="regulation of transcription, DNA-templated"/>
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0000981" name="DNA-binding transcription factor activity, RNA polymerase II-specific"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
          </entry>
          <signature-library-release library="PROSITE_PATTERNS" version="2021_01"/>
        </signature>
        <model-ac>PS00027</model-ac>
        <locations>
          <patternscan-location level="STRONG" start="173" end="196">
            <location-fragments>
              <patternscan-location-fragment start="173" end="196" dc-status="CONTINUOUS"/>
            </location-fragments>
            <alignment>LAatLgLTdaQVKVWFqNrrmkwR</alignment>
          </patternscan-location>
        </locations>
      </patternscan-match>
      <profilescan-match>
        <signature ac="PS50071" desc="'Homeobox' domain profile." name="HOMEOBOX_2">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="PROSITE_PROFILES" version="2021_01"/>
        </signature>
        <model-ac>PS50071</model-ac>
        <locations>
          <profilescan-location score="18.948925" start="138" end="198">
            <location-fragments>
              <profilescan-location-fragment start="138" end="198" dc-status="CONTINUOUS"/>
            </location-fragments>
            <alignment>RKRSWSRAVFSNLQRKGLERRFQLQKYITKPDRRQLAATLGLTDAQVKVWFQNRRMKWRHT</alignment>
          </profilescan-location>
        </locations>
      </profilescan-match>
      <rpsblast-match>
        <signature ac="cd00086" desc="homeodomain" name="homeodomain">
          <entry ac="IPR001356" desc="Homeobox domain" name="Homeobox_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0003677" name="DNA binding"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
          </entry>
          <signature-library-release library="CDD" version="3.18"/>
        </signature>
        <model-ac>cd00086</model-ac>
        <locations>
          <rpsblast-location evalue="4.15632E-20" score="78.4392" start="144" end="199">
            <location-fragments>
              <rpsblast-location-fragment start="144" end="199" dc-status="CONTINUOUS"/>
            </location-fragments>
            <sites>
              <rpsblast-site description="specific DNA base contacts" numLocations="5">
                <site-locations>
                  <site-location residue="V" start="146" end="146"/>
                  <site-location residue="V" start="186" end="186"/>
                  <site-location residue="M" start="193" end="193"/>
                  <site-location residue="N" start="190" end="190"/>
                  <site-location residue="Q" start="189" end="189"/>
                </site-locations>
              </rpsblast-site>
              <rpsblast-site description="DNA binding site" numLocations="15">
                <site-locations>
                  <site-location residue="Y" start="164" end="164"/>
                  <site-location residue="R" start="144" end="144"/>
                  <site-location residue="R" start="192" end="192"/>
                  <site-location residue="K" start="194" end="194"/>
                  <site-location residue="A" start="145" end="145"/>
                  <site-location residue="V" start="186" end="186"/>
                  <site-location residue="M" start="193" end="193"/>
                  <site-location residue="R" start="196" end="196"/>
                  <site-location residue="Q" start="183" end="183"/>
                  <site-location residue="N" start="190" end="190"/>
                  <site-location residue="F" start="147" end="147"/>
                  <site-location residue="R" start="170" end="170"/>
                  <site-location residue="Q" start="189" end="189"/>
                  <site-location residue="H" start="197" end="197"/>
                  <site-location residue="K" start="185" end="185"/>
                </site-locations>
              </rpsblast-site>
            </sites>
          </rpsblast-location>
        </locations>
      </rpsblast-match>
      <superfamilyhmmer3-match evalue="1.41E-21">
        <signature ac="SSF46689" name="Homeodomain-like">
          <entry ac="IPR009057" desc="Homeobox-like domain superfamily" name="Homeobox-like_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-BTA-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-MMU-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210746" name="Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-SCE-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-DRE-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-RNO-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-MMU-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-RNO-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400511" name="Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="Reactome" id="R-DME-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6526" name="limonene degradation III (to perillate)"/>
            <pathway-xref db="Reactome" id="R-HSA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866906" name="TFAP2 (AP-2) family regulates transcription of other transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-418124" name="Telomere maintenance"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892245" name="POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-MMU-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5661" name="GDP-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="Reactome" id="R-RNO-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-HSA-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-452723" name="Transcriptional regulation of pluripotent stem cells"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-DRE-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-BTA-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5601884" name="PIWI-interacting RNA (piRNA) biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-MMU-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="Reactome" id="R-HSA-8939902" name="Regulation of RUNX2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="Reactome" id="R-CEL-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-HSA-210747" name="Regulation of gene expression in early pancreatic precursor cells"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-9029569" name="NR1H3 &amp; NR1H2 regulate gene expression linked to cholesterol transport and efflux"/>
            <pathway-xref db="Reactome" id="R-CEL-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6689" name="tRNA splicing I"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-XTR-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8941855" name="RUNX3 regulates CDKN1A transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-SCE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-MMU-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-RNO-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-621" name="sucrose degradation III (sucrose invertase)"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-RNO-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5928" name="(4R)-carvone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-8029" name="limonene degradation IV (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-MMU-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210745" name="Regulation of gene expression in beta cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-606279" name="Deposition of new CENPA-containing nucleosomes at the centromere"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7250" name="[2Fe-2S] iron-sulfur cluster biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-749476" name="RNA Polymerase III Abortive And Retractive Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-110329" name="Cleavage of the damaged pyrimidine"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-RNO-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8869496" name="TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2722" name="trehalose degradation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-RNO-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="Reactome" id="R-XTR-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3232118" name="SUMOylation of transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-6436" name="perillyl aldehyde biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5689901" name="Metalloprotease DUBs"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381771" name="Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-1221632" name="Meiotic synapsis"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-RNO-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="Reactome" id="R-HSA-1368071" name="NR1D1 (REV-ERBA) represses gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-HSA-110328" name="Recognition and association of DNA glycosylase with site containing an affected pyrimidine"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="MetaCyc" id="PWY-7385" name="1,3-propanediol biosynthesis (engineered)"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76071" name="RNA Polymerase III Transcription Initiation From Type 3 Promoter"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8042" name="acylceramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5617472" name="Activation of anterior HOX genes in hindbrain development during early embryogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-2723" name="trehalose degradation V"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174430" name="Telomere C-strand synthesis initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-9022537" name="Loss of MECP2 binding ability to the NCoR/SMRT complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9623433" name="NR1H2 &amp; NR1H3 regulate gene expression to control bile acid homeostasis"/>
            <pathway-xref db="Reactome" id="R-DME-390193" name="Transcriptional activation by YKI"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9623433" name="NR1H2 &amp; NR1H3 regulate gene expression to control bile acid homeostasis"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-BTA-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="Reactome" id="R-XTR-110331" name="Cleavage of the damaged purine"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174414" name="Processive synthesis on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-3214842" name="HDMs demethylate histones"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-174437" name="Removal of the Flap Intermediate from the C-strand"/>
            <pathway-xref db="Reactome" id="R-DRE-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-DRE-174417" name="Telomere C-strand (Lagging Strand) Synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5514" name="UDP-N-acetyl-D-galactosamine biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CEL-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174411" name="Polymerase switching on the C-strand of the telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-DME-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9670095" name="Inhibition of DNA recombination at telomere"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-DDI-72163" name="mRNA Splicing - Major Pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-110330" name="Recognition and association of DNA glycosylase with site containing an affected purine"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-DRE-171306" name="Packaging Of Telomere Ends"/>
            <pathway-xref db="Reactome" id="R-RNO-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DRE-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SPO-76066" name="RNA Polymerase III Transcription Initiation From Type 2 Promoter"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-427389" name="ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214815" name="HDACs deacetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-2173795" name="Downregulation of SMAD2/3:SMAD4 transcriptional activity"/>
            <pathway-xref db="Reactome" id="R-SPO-76061" name="RNA Polymerase III Transcription Initiation From Type 1 Promoter"/>
            <pathway-xref db="Reactome" id="R-DME-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2032785" name="YAP1- and WWTR1 (TAZ)-stimulated gene expression"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
          </entry>
          <signature-library-release library="SUPERFAMILY" version="1.75"/>
        </signature>
        <model-ac>0045889</model-ac>
        <locations>
          <superfamilyhmmer3-location hmm-length="88" start="122" end="198">
            <location-fragments>
              <superfamilyhmmer3-location-fragment start="122" end="198" dc-status="CONTINUOUS"/>
            </location-fragments>
          </superfamilyhmmer3-location>
        </locations>
      </superfamilyhmmer3-match>
    </matches>
  </protein>
  <protein>
    <sequence md5="7fe295c5ded6104781c4431234685500">MFFILRHPNAGELMIAWQKYSAIGPEELNLQEGDLVELLDTEDPTISSPKRARLDPELEVKGEQLLDSAAAKHKLSVKPKRSRSSSRYSPTRTPLNARWLVRMVKGDKKQGWVPCQVLQTADEPQPGTGLPGDAAFRRQAVVKELVETEQEFVRDLDFVVQNYLIGSEREPRKPKLIKDNFELIFGNLKEISEFHRTVLMEGVKYYANEPHLLGKAFLRLERDFDKHVSYCKEEPLAQSFLDTCDVAREYFEELSHRLNDDKTIAEHLKLPIQRINDYQLLLKELVRYSACLGEDNSDLQKALELMLSVPHRAQDDKFTNSIEGYRGSIHKLGRLLAHDWFSVCFGDITKERYLFLFKARILISKVRRISEDRSVFQLKDIIRLPQVEVKDHPDDPFVFELFDKTAGHALTLTCHREQVKDFWLKEIKEFATEIEEGADDLQVLSGPASPPEPVLQQYQLPKEPPKIQVEVAQIIEESKLPRVVELQKKEDKVVEKKAVEVEKKGESVSVQKTVESKVEATSVIQKSSSIKTTVQTSTQQKVESVQKVQSSTKVETTAQTLDTVTHKADTLSQKVDTVPQKVETPTQKVEISQQKVETISQKIAAKSETAREAQSVTQKVETTQQKLETTSQKSATAEIQQKVEAVTQKVESASKQIAVDSEKQKLVNPVLSKTHISVDNRVSGSAIALSRDGSKSELADYGDSFRVNVAVGLNVDQEAMSRKHVSAYGTSEGYGEMSSSYSRYSSSAAGDSLSKRSLSIDSESRGSTTSYSRRSTALGSAALDETSGRKSLRSDEGDYSYKRTSLAGEGDYSYRKSTALDEGDYSYRKSAAVDEGDYSYRKSRLADDSEYSFSRRSIKDKHHETSAYDAEDSYVSKRRSERLSSKASVEDDFDADAYVSKIKSDSYRRLTSTDSTDSYKRSLSNQGEEEDRLAKFEKYSRRSSSEQGKYNRTDSIGAETNERSDSFQTVTQSTVFDGKILEDAVKKSKSKDIGMAPPDETPKFTKTLGGIHIKLTEEEKEELKKPDFTVKLKDTELLEDTYLRFMLKIRGEPHPILTFYKDNVKIQDSERIKVNRDLSDHDFYELVIPDVKPQDAGVYKCVAINEHGEACTEAKVTVTESKHLFDDLPNKEIPLPPGEKPSFIWKKDGKEFEAEERFKVLLGDDEDSLALIFQHVKPEDAGLYTCVAQTTTGNISCSAELTVQGTVHELYREPEKPQLIIEKREAITSVGGSCIMELQVKGFPKPKVTWKHEGEAVEPSQKYKFLHEDEETMSLVIKNVEAKDAGRYEITAENELGQDIREMHLTVKAPPTICKMTDTTASTEQELKMTAEIDGIPKPTVQFYKDGKIIKNTELISIVEEGNKYSIVIKNTTLKDSGSYSVVASNEMAQVSQFWNLEIYCKPKILKKIGENKSISQKAEVELSIKMESQPPPEITWFKDGVEIKSDGHYIISDDGETYKLKITGSVTTDSASYKVRAKNIHGTSEDEARVDVKRAPTIVQALEDMTVTEHDKNVTLGLKVDAFPKPTVKWFLDEVEIQETRTEYTKIEADDGLKLVIKEVGSELSGKYTCKVINELGETSTSAKLTVNCKPKVIKQLKDTTVEEGATLHLECEVEAVPEPTVKWLRNGKEVSADARIKITRDTKRFENYHLSVNLIKYEEQGEYEIQVTNTLGTVSSKSNVTVHKVSHTDAIEEEAPVKLKLIVDEVTTDEFKIEEVIEEPEQCQIGDKMIVEEGKVEEPQPIVEEEILTVKKRAKSAGTDVCEIMEVEEPTTPEATKPAEPQKAEVEDDDIEALLERAKKQRSLVEEIGAQALPTITESNMKDRSQFESLGTVFSVTTNGNPAPTAAWTLNGSLIKPGANQRFKIMDEGNVHKLEIIRLQPADAGVYECTISNCVGDIKQQSKLEIIPEAELRRPKVREGLGLQDTTVIKKKEAVLKAVIVGEPVPEFTWCFKGKEITPEEFEKYKMVIEAEDKDIEDTLKECTFSLTIPRCERINGGEYSLKLKNKWGETTSSGVLTVVLSPEIEGPDFVKVVPGDATELTCIIQSNPKAIVTWTKSENVIEAGGDIEILEDLENERYTLKFNKVQLSDEGYYKVYAKNEYGEANSEGRIKTIKEPEPSTEKPQFITGLTDGHVEHGGEISLMVRADGLPRPEIKWFLNNKEIVDVPELQFATTSDRQITSTMTIINYGENDSGLYKVTATNVVGDAETSAKVTMLQTPPSFAKRLERSEEVNEGEKLELKAKISGSPKPQVAWYKDGEKIDADDKRIKTEHLPDGTVKLKIVAVTPADSGAYKLVVKNQNGETAGLCAVVVNASAKRPKFTKCIKDTKVMVGEPLKLTANVAAYPPPEIKWMKDGLPVRASSNIHMEHHPDGTIALVVDNVRPENAGKYTLIVANKVGEITGEANVEIEKRPIKPDFITRIYPQTVVEGFPVKFEVKVSGFPQPSIIWRRNGAEVISDNKHIKITDLPDGGSALVIDACDQLRDALTYYAIATNEAGEAESSALLTVTSATKGDQPEERPMFLHALRDIITDEGQELKMEAPFTGNPIPSVEWTKDGQPIVPSDRILLTCDGKKVGLRIDHSLPSDAGLYGVRIVNPLGSETSQAKASVHKVFQAPSFTQRFTDLQQLPKRDAKFPVRVSGVPQPEVSWSKDGVPLRDSDKYRIKRDGDACCLYIANCLPEDEGSYTATATNKEGQDTCMARLEVVKEIKTQKKIEPANFVKRIGDTELYKGMTAKFTACAAGIPEPTVEWYRNDQRMYPADRIKMEMDRNGLLRLTVAGVDQDDLGKYTCKIYNDHGSDSCDAYLRFDEGMEARPKKPITDQYSDFDKYKKSGAPMPLSDAPIISRMTDRHCTLSWKPSIPSGPRFPVTYQLEMLEHPHGDWFTVRSGIRSCCCDVRNLEPFRDYKFRVRVENKYGISDPSPYAMTHREKLEPEPIKFMPYLPPGIDFRPETSPYFPKDFDIDRPPHDNMAQAPRFLRQEHDAQYGVKDQNTNLFWFVYGYPKPKMAYYFNDELIEPGGRFDMSYTRNGQATLFINKMLERDVGWYEAVATNEHGEARQRVRLEIAEAPIFIRRPDIEYVMVRGKARFEARILGVPYPEIKWYRDWKPVANSTRIKIQFMEPDTAILVINDAIFKDEGLYSVSARNVAGSISSSAMLHIEENDLEYNIRTYNNPNPIKLRKKPYSDAYDIGDELGRGTQGVTYHAVERLNGRNYAAKIMHSRGELKPMMYNEWEIMNQLHHRRLISLHDAYEHDDCLALVMELAGGGELVKDYLIKQEYYTESEIAGYIRQLLQGLQYMHERGFGHMGLNIGDLLLSHPGSDELKIGDFGLSRRVQMGRLYPLKYGMPEYVSPEAANGEGTGLGHDMWSVGIITYILLSGHSPFRGMHDMETLMNIQAGKWKFEDSWWSNMSLECRDFISKLLIYQADGRLDVHAALRHPWLERADKSWRDEYMISTTYLRDYFVLYREWYDNASCRKWFRRRPLEGAFTHPSRMVYPPGERSTPPPAKTPERVAHKPRTWEDQIPTRSPLNYEIGAFKSESHYQNGPDTYLLQLRDVDFPVRLREYMKVAGSRGPGHAHIVSNENGYDWATPVIRERRRFTDVMDEEIDDERKARISKYGTGDMGFTIRRLRHEIGTRLDTYAEAEAFLESKMEGRLPFFREKPQITALQEGKDLEMICMAVGDPDPIVQWFKNDAIIAESHRIKIQVDEHGRSHLKLSPALGFDAGLYKVVARNKIGQTISRTRIVLGTVPDAPDSPEGTQVSDTEVLLSWKQPKHDGHSPVICYSVQFKLADDMEWSDKANNIDHEFYLMKELEAGKNYIFRLAAKNEMGWSDFGVASPVIMTQPTGAAKVQISKAMMHLQQITDAGGEVVVEPRNQLDYNVETKPVDWIKGDPQEKYNFISEIARGKFSAVVKALDKSSDQVFVAKLIDTGSLGADNIEGEFAALRSLRHERIATLFEAYRASDGNSVFIMEKLQGADVLTYLSTRHEYTEQTVAIIVSQVLDGIQYLHWRGLCHLDLQPDNVVMCGVRSVQVKLVDFGSAHRVTKLGNKVPVVGHPDYVAPEVLSDEPAFPQTDIWQVGVLTYVMLSGTLPFKGADDNESRQNTLFVRFRFEHLYKEVSQEGVRFVMLLFKRHPNKRPTAEECQENRWLLPTDSMIKKRERAVFLGNRLKEYSEAYHAEKSADSTSLGGRLNRSQSLQEELLTAPF</sequence>
    <xref id="XP_017774924.1" name="XP_017774924.1 PREDICTED: muscle M-line assembly protein unc-89 isoform X2 [Nicrophorus vespilloides]"/>
    <matches>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="636" end="656">
            <location-fragments>
              <coils-location-fragment start="636" end="656" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="613" end="633">
            <location-fragments>
              <coils-location-fragment start="613" end="633" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <coils-match>
        <signature ac="Coil" name="Coil">
          <signature-library-release library="COILS" version="2.2.1"/>
        </signature>
        <model-ac>Coil</model-ac>
        <locations>
          <coils-location start="2073" end="2093">
            <location-fragments>
              <coils-location-fragment start="2073" end="2093" dc-status="CONTINUOUS"/>
            </location-fragments>
          </coils-location>
        </locations>
      </coils-match>
      <hmmer2-match evalue="6.7E-23" score="92.1">
        <signature ac="SM00060" name="FN3_2">
          <entry ac="IPR003961" desc="Fibronectin type III" name="FN3_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6348" name="phosphate acquisition"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00060</model-ac>
        <locations>
          <hmmer2-location score="48.8" evalue="6.9E-10" hmm-start="1" hmm-end="69" hmm-length="69" hmm-bounds="COMPLETE" start="3758" end="3840">
            <location-fragments>
              <hmmer2-location-fragment start="3758" end="3840" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="43.2" evalue="3.4E-8" hmm-start="1" hmm-end="69" hmm-length="69" hmm-bounds="COMPLETE" start="2840" end="2923">
            <location-fragments>
              <hmmer2-location-fragment start="2840" end="2923" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer2-match evalue="1.6E-136" score="469.5">
        <signature ac="SM00409" name="IG_3c">
          <entry ac="IPR003599" desc="Immunoglobulin subtype" name="Ig_sub" type="DOMAIN">
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00409</model-ac>
        <locations>
          <hmmer2-location score="38.7" evalue="7.7E-7" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2328" end="2413">
            <location-fragments>
              <hmmer2-location-fragment start="2328" end="2413" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="27.4" evalue="0.0019" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1223" end="1308">
            <location-fragments>
              <hmmer2-location-fragment start="1223" end="1308" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="21.4" evalue="0.12" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2530" end="2614">
            <location-fragments>
              <hmmer2-location-fragment start="2530" end="2614" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="17.0" evalue="2.3" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1316" end="1400">
            <location-fragments>
              <hmmer2-location-fragment start="1316" end="1400" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="37.3" evalue="2.1E-6" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1598" end="1685">
            <location-fragments>
              <hmmer2-location-fragment start="1598" end="1685" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="36.5" evalue="3.6E-6" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2230" end="2316">
            <location-fragments>
              <hmmer2-location-fragment start="2230" end="2316" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="17.6" evalue="1.7" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1410" end="1494">
            <location-fragments>
              <hmmer2-location-fragment start="1410" end="1494" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="14.6" evalue="4.3" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1825" end="1909">
            <location-fragments>
              <hmmer2-location-fragment start="1825" end="1909" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="26.9" evalue="0.0028" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2626" end="2710">
            <location-fragments>
              <hmmer2-location-fragment start="2626" end="2710" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="22.8" evalue="0.047" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1141" end="1204">
            <location-fragments>
              <hmmer2-location-fragment start="1141" end="1204" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="17.8" evalue="1.5" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2425" end="2512">
            <location-fragments>
              <hmmer2-location-fragment start="2425" end="2512" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="31.2" evalue="1.4E-4" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2030" end="2116">
            <location-fragments>
              <hmmer2-location-fragment start="2030" end="2116" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="1.9" evalue="130.0" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2986" end="3071">
            <location-fragments>
              <hmmer2-location-fragment start="2986" end="3071" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="10.2" evalue="14.0" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1925" end="2023">
            <location-fragments>
              <hmmer2-location-fragment start="1925" end="2023" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="26.9" evalue="0.0028" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="694" end="1119">
            <location-fragments>
              <hmmer2-location-fragment start="694" end="1119" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="19.9" evalue="0.36" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="3670" end="3755">
            <location-fragments>
              <hmmer2-location-fragment start="3670" end="3755" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="22.3" evalue="0.07" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2728" end="2813">
            <location-fragments>
              <hmmer2-location-fragment start="2728" end="2813" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="24.6" evalue="0.014" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="2132" end="2219">
            <location-fragments>
              <hmmer2-location-fragment start="2132" end="2219" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="23.6" evalue="0.027" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="3080" end="3165">
            <location-fragments>
              <hmmer2-location-fragment start="3080" end="3165" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="30.7" evalue="2.0E-4" hmm-start="1" hmm-end="58" hmm-length="58" hmm-bounds="COMPLETE" start="1503" end="1589">
            <location-fragments>
              <hmmer2-location-fragment start="1503" end="1589" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer2-match evalue="5.8E-26" score="102.3">
        <signature ac="SM00325" name="RhoGEF_3">
          <entry ac="IPR000219" desc="Dbl homology (DH) domain" name="DH-domain" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005085" name="guanyl-nucleotide exchange factor activity"/>
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-XTR-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-SCE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-DME-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DME-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DRE-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-DME-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-XTR-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DDI-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-DME-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9013148" name="CDC42 GTPase cycle"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00325</model-ac>
        <locations>
          <hmmer2-location score="102.3" evalue="5.8E-26" hmm-start="1" hmm-end="211" hmm-length="211" hmm-bounds="COMPLETE" start="141" end="315">
            <location-fragments>
              <hmmer2-location-fragment start="141" end="315" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer2-match evalue="6.1E-104" score="361.3">
        <signature ac="SM00408" name="igc2_5">
          <entry ac="IPR003598" desc="Immunoglobulin subtype 2" name="Ig_sub2" type="DOMAIN">
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
          </entry>
          <signature-library-release library="SMART" version="7.1"/>
        </signature>
        <model-ac>SM00408</model-ac>
        <locations>
          <hmmer2-location score="3.9" evalue="2.2" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="3089" end="3154">
            <location-fragments>
              <hmmer2-location-fragment start="3089" end="3154" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="11.4" evalue="0.36" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2734" end="2802">
            <location-fragments>
              <hmmer2-location-fragment start="2734" end="2802" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="19.8" evalue="0.048" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1229" end="1297">
            <location-fragments>
              <hmmer2-location-fragment start="1229" end="1297" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="12.8" evalue="0.26" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1038" end="1108">
            <location-fragments>
              <hmmer2-location-fragment start="1038" end="1108" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="28.8" evalue="7.2E-4" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2334" end="2402">
            <location-fragments>
              <hmmer2-location-fragment start="2334" end="2402" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="36.4" evalue="3.8E-6" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="3676" end="3744">
            <location-fragments>
              <hmmer2-location-fragment start="3676" end="3744" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="25.7" evalue="0.0066" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2536" end="2603">
            <location-fragments>
              <hmmer2-location-fragment start="2536" end="2603" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="28.4" evalue="0.001" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1510" end="1578">
            <location-fragments>
              <hmmer2-location-fragment start="1510" end="1578" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="31.2" evalue="1.5E-4" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2236" end="2305">
            <location-fragments>
              <hmmer2-location-fragment start="2236" end="2305" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="4.7" evalue="1.8" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1322" end="1389">
            <location-fragments>
              <hmmer2-location-fragment start="1322" end="1389" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="22.1" evalue="0.027" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1128" end="1193">
            <location-fragments>
              <hmmer2-location-fragment start="1128" end="1193" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="4.6" evalue="1.9" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1416" end="1483">
            <location-fragments>
              <hmmer2-location-fragment start="1416" end="1483" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="5.0" evalue="1.7" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2431" end="2501">
            <location-fragments>
              <hmmer2-location-fragment start="2431" end="2501" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="23.3" evalue="0.02" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2138" end="2208">
            <location-fragments>
              <hmmer2-location-fragment start="2138" end="2208" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="33.8" evalue="2.3E-5" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2036" end="2105">
            <location-fragments>
              <hmmer2-location-fragment start="2036" end="2105" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="21.1" evalue="0.035" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1831" end="1898">
            <location-fragments>
              <hmmer2-location-fragment start="1831" end="1898" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="34.5" evalue="1.4E-5" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="1604" end="1674">
            <location-fragments>
              <hmmer2-location-fragment start="1604" end="1674" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
          <hmmer2-location score="13.7" evalue="0.2" hmm-start="1" hmm-end="56" hmm-length="56" hmm-bounds="COMPLETE" start="2632" end="2699">
            <location-fragments>
              <hmmer2-location-fragment start="2632" end="2699" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer2-location>
        </locations>
      </hmmer2-match>
      <hmmer3-match evalue="0.0" score="1295.6">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3qp3A00</model-ac>
        <locations>
          <hmmer3-location env-end="2712" env-start="2614" post-processed="true" score="79.5" evalue="6.7E-22" hmm-start="7" hmm-end="98" hmm-length="103" hmm-bounds="C_TERMINAL_COMPLETE" start="2616" end="2712">
            <location-fragments>
              <hmmer3-location-fragment start="2616" end="2712" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="1122" env-start="1022" post-processed="true" score="72.1" evalue="1.3E-19" hmm-start="7" hmm-end="99" hmm-length="103" hmm-bounds="COMPLETE" start="1022" end="1122">
            <location-fragments>
              <hmmer3-location-fragment start="1022" end="1122" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="1495" env-start="1399" post-processed="true" score="69.6" evalue="8.1E-19" hmm-start="8" hmm-end="99" hmm-length="103" hmm-bounds="INCOMPLETE" start="1404" end="1494">
            <location-fragments>
              <hmmer3-location-fragment start="1404" end="1494" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="1687" env-start="1588" post-processed="true" score="82.7" evalue="6.9E-23" hmm-start="6" hmm-end="98" hmm-length="103" hmm-bounds="C_TERMINAL_COMPLETE" start="1592" end="1687">
            <location-fragments>
              <hmmer3-location-fragment start="1592" end="1687" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.8E-40" score="139.6">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1uemA00</model-ac>
        <locations>
          <hmmer3-location env-end="2935" env-start="2830" post-processed="true" score="58.2" evalue="3.3E-15" hmm-start="16" hmm-end="104" hmm-length="117" hmm-bounds="COMPLETE" start="2830" end="2935">
            <location-fragments>
              <hmmer3-location-fragment start="2830" end="2935" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1148.0">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1wwcA00</model-ac>
        <locations>
          <hmmer3-location env-end="1921" env-start="1813" post-processed="true" score="54.8" evalue="3.4E-14" hmm-start="9" hmm-end="102" hmm-length="118" hmm-bounds="N_TERMINAL_COMPLETE" start="1813" end="1920">
            <location-fragments>
              <hmmer3-location-fragment start="1813" end="1920" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="2130" env-start="2018" post-processed="true" score="62.0" evalue="2.0E-16" hmm-start="3" hmm-end="107" hmm-length="118" hmm-bounds="INCOMPLETE" start="2023" end="2126">
            <location-fragments>
              <hmmer3-location-fragment start="2023" end="2126" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.6E-36" score="127.1">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>5fm5M00</model-ac>
        <locations>
          <hmmer3-location env-end="3874" env-start="3757" post-processed="true" score="68.3" evalue="2.6E-18" hmm-start="2" hmm-end="108" hmm-length="124" hmm-bounds="C_TERMINAL_COMPLETE" start="3760" end="3874">
            <location-fragments>
              <hmmer3-location-fragment start="3760" end="3874" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1279.7">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2kkqA00</model-ac>
        <locations>
          <hmmer3-location env-end="1313" env-start="1206" post-processed="true" score="77.0" evalue="4.4E-21" hmm-start="11" hmm-end="111" hmm-length="116" hmm-bounds="INCOMPLETE" start="1209" end="1310">
            <location-fragments>
              <hmmer3-location-fragment start="1209" end="1310" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="3074" env-start="2969" post-processed="true" score="50.6" evalue="6.8E-13" hmm-start="12" hmm-end="111" hmm-length="116" hmm-bounds="N_TERMINAL_COMPLETE" start="2969" end="3072">
            <location-fragments>
              <hmmer3-location-fragment start="2969" end="3072" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1056.4">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>4rsvA00</model-ac>
        <locations>
          <hmmer3-location env-end="1211" env-start="1135" post-processed="true" score="49.7" evalue="1.2E-12" hmm-start="32" hmm-end="93" hmm-length="102" hmm-bounds="N_TERMINAL_COMPLETE" start="1135" end="1208">
            <location-fragments>
              <hmmer3-location-fragment start="1135" end="1208" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1291.6">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2cqvA00</model-ac>
        <locations>
          <hmmer3-location env-end="1594" env-start="1493" post-processed="true" score="74.5" evalue="2.5E-20" hmm-start="6" hmm-end="102" hmm-length="114" hmm-bounds="INCOMPLETE" start="1495" end="1591">
            <location-fragments>
              <hmmer3-location-fragment start="1495" end="1591" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="1408" env-start="1308" post-processed="true" score="63.6" evalue="6.3E-17" hmm-start="7" hmm-end="102" hmm-length="114" hmm-bounds="INCOMPLETE" start="1311" end="1403">
            <location-fragments>
              <hmmer3-location-fragment start="1311" end="1403" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="2420" env-start="2316" post-processed="true" score="78.2" evalue="1.8E-21" hmm-start="6" hmm-end="104" hmm-length="114" hmm-bounds="INCOMPLETE" start="2319" end="2417">
            <location-fragments>
              <hmmer3-location-fragment start="2319" end="2417" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="2224" env-start="2122" post-processed="true" score="65.6" evalue="1.5E-17" hmm-start="6" hmm-end="101" hmm-length="114" hmm-bounds="INCOMPLETE" start="2127" end="2221">
            <location-fragments>
              <hmmer3-location-fragment start="2127" end="2221" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="3170" env-start="3071" post-processed="true" score="61.8" evalue="2.2E-16" hmm-start="6" hmm-end="99" hmm-length="114" hmm-bounds="INCOMPLETE" start="3073" end="3167">
            <location-fragments>
              <hmmer3-location-fragment start="3073" end="3167" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="5.9E-41" score="140.7">
        <signature ac="G3DSA:3.30.200.20" name="Phosphorylase Kinase; domain 1">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1kobA01</model-ac>
        <locations>
          <hmmer3-location env-end="3269" env-start="3165" post-processed="true" score="85.1" evalue="1.1E-23" hmm-start="11" hmm-end="107" hmm-length="109" hmm-bounds="C_TERMINAL_COMPLETE" start="3168" end="3269">
            <location-fragments>
              <hmmer3-location-fragment start="3168" end="3269" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1100.5">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>4crpA00</model-ac>
        <locations>
          <hmmer3-location env-end="2026" env-start="1919" post-processed="true" score="49.3" evalue="1.8E-12" hmm-start="12" hmm-end="106" hmm-length="107" hmm-bounds="INCOMPLETE" start="1921" end="2022">
            <location-fragments>
              <hmmer3-location-fragment start="1921" end="2022" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1284.5">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2dm2A00</model-ac>
        <locations>
          <hmmer3-location env-end="2320" env-start="2218" post-processed="true" score="74.9" evalue="1.9E-20" hmm-start="7" hmm-end="101" hmm-length="110" hmm-bounds="INCOMPLETE" start="2222" end="2318">
            <location-fragments>
              <hmmer3-location-fragment start="2222" end="2318" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
          <hmmer3-location env-end="2815" env-start="2714" post-processed="true" score="69.9" evalue="7.0E-19" hmm-start="7" hmm-end="100" hmm-length="110" hmm-bounds="COMPLETE" start="2714" end="2815">
            <location-fragments>
              <hmmer3-location-fragment start="2714" end="2815" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1247.4">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>2dm3A00</model-ac>
        <locations>
          <hmmer3-location env-end="3761" env-start="3657" post-processed="true" score="61.5" evalue="2.5E-16" hmm-start="10" hmm-end="98" hmm-length="110" hmm-bounds="N_TERMINAL_COMPLETE" start="3657" end="3759">
            <location-fragments>
              <hmmer3-location-fragment start="3657" end="3759" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="3.3E-37" score="130.1">
        <signature ac="G3DSA:1.20.900.10" name="Dbl homology (DH) domain">
          <entry ac="IPR035899" desc="Dbl homology (DH) domain superfamily" name="DBL_dom_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-DME-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-XTR-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-SCE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-DME-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DME-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DRE-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-DME-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-XTR-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-DME-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DDI-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-DME-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-9013148" name="CDC42 GTPase cycle"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1kz7A01</model-ac>
        <locations>
          <hmmer3-location env-end="317" env-start="133" post-processed="true" score="128.9" evalue="7.8E-37" hmm-start="11" hmm-end="190" hmm-length="195" hmm-bounds="COMPLETE" start="133" end="317">
            <location-fragments>
              <hmmer3-location-fragment start="133" end="317" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="6.1E-25" score="89.7">
        <signature ac="G3DSA:2.30.29.30" name="">
          <entry ac="IPR011993" desc="PH-like domain superfamily" name="PH-like_dom_sf" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-DRE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-DME-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-DME-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-1483166" name="Synthesis of PA"/>
            <pathway-xref db="Reactome" id="R-MMU-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-HSA-1368108" name="BMAL1:CLOCK,NPAS2 activates circadian gene expression"/>
            <pathway-xref db="Reactome" id="R-BTA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-XTR-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-HSA-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-SPO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-9031525" name="NR1H2 &amp; NR1H3 regulate gene expression to limit cholesterol uptake"/>
            <pathway-xref db="Reactome" id="R-CEL-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DDI-2485179" name="Activation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-DDI-156588" name="Glucuronidation"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013419" name="RHOT2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-GGA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-RNO-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-HSA-167243" name="Tat-mediated HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DME-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-BTA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-CEL-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8964026" name="Chylomicron clearance"/>
            <pathway-xref db="Reactome" id="R-CEL-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DME-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-6841" name="homophytochelatin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-HSA-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-GGA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-CEL-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-DME-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-DME-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-CEL-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-HSA-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-MMU-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-RNO-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DRE-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DME-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DME-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-HSA-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-XTR-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112314" name="Neurotransmitter receptors and postsynaptic signal transmission"/>
            <pathway-xref db="Reactome" id="R-DRE-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CEL-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DME-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DME-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-167158" name="Formation of the HIV-1 Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6463" name="peptidoglycan cross-bridge biosynthesis IV (Weissella viridescens)"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-DME-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-RNO-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-165054" name="Rev-mediated nuclear export of HIV RNA"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-BTA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DDI-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-RNO-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-MMU-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7887" name="protein SAMPylation and SAMP-mediated thiolation"/>
            <pathway-xref db="Reactome" id="R-HSA-9707616" name="Heme signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-XTR-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-SCE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-DDI-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-CEL-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-MMU-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-DME-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-GGA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DDI-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-MMU-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-GGA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6351" name="D-myo-inositol (1,4,5)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DRE-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-SPO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-CEL-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-CEL-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-MMU-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-SPO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DRE-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-CEL-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-DDI-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DME-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SPO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-DDI-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DDI-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-110523" name="TOR signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-DME-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849474" name="PTK6 Activates STAT3"/>
            <pathway-xref db="Reactome" id="R-DME-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-DDI-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-DDI-170670" name="Adenylate cyclase inhibitory pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-CFA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-DME-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-168276" name="NS1 Mediated Effects on Host Pathways"/>
            <pathway-xref db="Reactome" id="R-MMU-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-1483166" name="Synthesis of PA"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-DDI-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-SCE-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-3561" name="choline biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-5602498" name="MyD88 deficiency (TLR2/4)"/>
            <pathway-xref db="Reactome" id="R-MMU-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-DDI-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DRE-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-DME-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6580" name="phosphatidylinositol biosynthesis I (bacteria)"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-180746" name="Nuclear import of Rev protein"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SCE-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-SCE-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-BTA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-BTA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-BTA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-SPO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-DDI-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DME-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SCE-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="Reactome" id="R-RNO-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-BTA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-GGA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854521" name="Interaction between PHLDA1 and AURKA"/>
            <pathway-xref db="Reactome" id="R-HSA-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-DRE-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-RNO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-CEL-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-DME-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DME-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-DDI-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DME-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-SCE-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-XTR-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-MMU-166016" name="Toll Like Receptor 4 (TLR4) Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="Reactome" id="R-GGA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1251932" name="PLCG1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6784531" name="tRNA processing in the nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-RNO-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-DDI-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SSC-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-HSA-211728" name="Regulation of PAK-2p34 activity by PS-GAP/RHG10"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-DDI-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-5637810" name="Constitutive Signaling by EGFRvIII"/>
            <pathway-xref db="Reactome" id="R-DDI-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1482801" name="Acyl chain remodelling of PS"/>
            <pathway-xref db="Reactome" id="R-RNO-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DDI-9013425" name="RHOT1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-SPO-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-167290" name="Pausing and recovery of HIV elongation"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-RNO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-MMU-212718" name="EGFR interacts with phospholipase C-gamma"/>
            <pathway-xref db="Reactome" id="R-SSC-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-5666185" name="RHO GTPases Activate Rhotekin and Rhophilins"/>
            <pathway-xref db="Reactome" id="R-DDI-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-CEL-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-RNO-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-DDI-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-SPO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-SPO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DDI-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9609736" name="Assembly and cell surface presentation of NMDA receptors"/>
            <pathway-xref db="Reactome" id="R-GGA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483148" name="Synthesis of PG"/>
            <pathway-xref db="Reactome" id="R-DDI-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-SCE-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-DDI-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-RNO-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-SPO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-MMU-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-DME-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-DME-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-180910" name="Vpr-mediated nuclear import of PICs"/>
            <pathway-xref db="Reactome" id="R-HSA-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-SCE-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-CEL-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8941332" name="RUNX2 regulates genes involved in cell migration"/>
            <pathway-xref db="Reactome" id="R-MMU-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DRE-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-XTR-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-MMU-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-GGA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="Reactome" id="R-SPO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802953" name="RAS signaling downstream of NF1 loss-of-function variants"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-CEL-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-167238" name="Pausing and recovery of Tat-mediated HIV elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-RNO-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9662361" name="Sensory processing of sound by outer hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-9648895" name="Response of EIF2AK1 (HRI) to heme deficiency"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-CEL-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SPO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-HSA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-SCE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DME-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SPO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-DME-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-SPO-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-DDI-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-HSA-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-DME-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1839117" name="Signaling by cytosolic FGFR1 fusion mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-DME-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-SPO-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-MMU-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-SPO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-SSC-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-CEL-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8964026" name="Chylomicron clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-HSA-8950505" name="Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-DDI-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-SCE-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-168271" name="Transport of Ribonucleoproteins into the Host Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-1368082" name="RORA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-CEL-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-BTA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-DME-9707564" name="Cytoprotection by HMOX1"/>
            <pathway-xref db="Reactome" id="R-CEL-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-DRE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964026" name="Chylomicron clearance"/>
            <pathway-xref db="Reactome" id="R-SCE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-9662360" name="Sensory processing of sound by inner hair cells of the cochlea"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-5626978" name="TNFR1-mediated ceramide production"/>
            <pathway-xref db="Reactome" id="R-MMU-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-RNO-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-167160" name="RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-170822" name="Regulation of Glucokinase by Glucokinase Regulatory Protein"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-SPO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-CEL-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-BTA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-112399" name="IRS-mediated signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-159230" name="Transport of the SLBP Dependant Mature mRNA"/>
            <pathway-xref db="MetaCyc" id="PWY-6289" name="petrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-112412" name="SOS-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-DME-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DDI-1169092" name="Activation of RAS in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-1489509" name="DAG and IP3 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-170660" name="Adenylate cyclase activating pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-DME-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-8853659" name="RET signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-168325" name="Viral Messenger RNA Synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-BTA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-MMU-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-SPO-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-MMU-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-6804114" name="TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-BTA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-CEL-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DME-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-6811434" name="COPI-dependent Golgi-to-ER retrograde traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-SCE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-212718" name="EGFR interacts with phospholipase C-gamma"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-RNO-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-XTR-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-MMU-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CEL-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-DME-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-MMU-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-HSA-164944" name="Nef and signal transduction"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DME-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-CEL-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-CEL-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-GGA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-DDI-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DDI-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-SCE-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-CEL-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-444473" name="Formyl peptide receptors bind formyl peptides and many other ligands"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-GGA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-DME-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-BTA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-CEL-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-BTA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6462" name="peptidoglycan cross-bridge biosynthesis III (Enterococcus faecalis)"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-CFA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-SCE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-DRE-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-2426168" name="Activation of gene expression by SREBF (SREBP)"/>
            <pathway-xref db="Reactome" id="R-SPO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-430039" name="mRNA decay by 5' to 3' exoribonuclease"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SCE-156588" name="Glucuronidation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-DME-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-975957" name="Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"/>
            <pathway-xref db="Reactome" id="R-HSA-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-HSA-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-SCE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1483248" name="Synthesis of PIPs at the ER membrane"/>
            <pathway-xref db="Reactome" id="R-DME-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-BTA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-CEL-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-432720" name="Lysosome Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1483166" name="Synthesis of PA"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-GGA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-202040" name="G-protein activation"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-HSA-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-MMU-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-RNO-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-DME-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-HSA-168333" name="NEP/NS2 Interacts with the Cellular Export Machinery"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-RNO-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-CEL-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-DME-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-SCE-189483" name="Heme degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-BTA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CEL-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-XTR-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-CEL-5610780" name="Degradation of GLI1 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-RNO-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-451806" name="Phosphorylation-independent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SCE-112043" name="PLC beta mediated events"/>
            <pathway-xref db="Reactome" id="R-BTA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DME-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-CEL-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7039" name="phosphatidate metabolism, as a signaling molecule"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-DME-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-SPO-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-6807878" name="COPI-mediated anterograde transport"/>
            <pathway-xref db="Reactome" id="R-DME-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-191859" name="snRNP Assembly"/>
            <pathway-xref db="Reactome" id="R-GGA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-XTR-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-RNO-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DDI-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SPO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-CEL-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SCE-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-111447" name="Activation of BAD and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-DME-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-RNO-192105" name="Synthesis of bile acids and bile salts"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-SPO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849474" name="PTK6 Activates STAT3"/>
            <pathway-xref db="Reactome" id="R-SPO-159231" name="Transport of Mature mRNA Derived from an Intronless Transcript"/>
            <pathway-xref db="Reactome" id="R-RNO-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-212718" name="EGFR interacts with phospholipase C-gamma"/>
            <pathway-xref db="Reactome" id="R-HSA-3232142" name="SUMOylation of ubiquitinylation proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-RNO-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-MMU-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-SPO-159236" name="Transport of Mature mRNA derived from an Intron-Containing Transcript"/>
            <pathway-xref db="Reactome" id="R-DRE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-RNO-444473" name="Formyl peptide receptors bind formyl peptides and many other ligands"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-HSA-8862803" name="Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-DME-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-1483166" name="Synthesis of PA"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-RNO-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-HSA-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-165160" name="PDE3B signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DDI-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-5603041" name="IRAK4 deficiency (TLR2/4)"/>
            <pathway-xref db="Reactome" id="R-DDI-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-4085377" name="SUMOylation of SUMOylation proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619107" name="Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-GGA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-SPO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="Reactome" id="R-MMU-1482801" name="Acyl chain remodelling of PS"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-196025" name="Formation of annular gap junctions"/>
            <pathway-xref db="Reactome" id="R-HSA-5620922" name="BBSome-mediated cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-4551638" name="SUMOylation of chromatin organization proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-3108214" name="SUMOylation of DNA damage response and repair proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-203641" name="NOSTRIN mediated eNOS trafficking"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-RNO-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-167162" name="RNA Polymerase II HIV Promoter Escape"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-XTR-5658442" name="Regulation of RAS by GAPs"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-SSC-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-SCE-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-DDI-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-DDI-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-444473" name="Formyl peptide receptors bind formyl peptides and many other ligands"/>
            <pathway-xref db="Reactome" id="R-CEL-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-400206" name="Regulation of lipid metabolism by PPARalpha"/>
            <pathway-xref db="Reactome" id="R-HSA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-GGA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-DME-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6367" name="D-myo-inositol-5-phosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-CEL-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-159227" name="Transport of the SLBP independent Mature mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4570464" name="SUMOylation of RNA binding proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-BTA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DME-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-5696400" name="Dual Incision in GG-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-CEL-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-983189" name="Kinesins"/>
            <pathway-xref db="Reactome" id="R-DDI-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SCE-917729" name="Endosomal Sorting Complex Required For Transport (ESCRT)"/>
            <pathway-xref db="Reactome" id="R-DDI-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-MMU-8866427" name="VLDLR internalisation and degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-6811438" name="Intra-Golgi traffic"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-SPO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DME-190873" name="Gap junction degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5578749" name="Transcriptional regulation by small RNAs"/>
            <pathway-xref db="Reactome" id="R-DME-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-GGA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-SPO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-167287" name="HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-2453902" name="The canonical retinoid cycle in rods (twilight vision)"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SCE-434316" name="Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-RNO-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-418555" name="G alpha (s) signalling events"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>1kz7C02</model-ac>
        <locations>
          <hmmer3-location env-end="443" env-start="321" post-processed="true" score="89.7" evalue="6.1E-25" hmm-start="2" hmm-end="131" hmm-length="158" hmm-bounds="COMPLETE" start="321" end="443">
            <location-fragments>
              <hmmer3-location-fragment start="321" end="443" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="3.5E-20" score="72.2">
        <signature ac="PF00041" desc="Fibronectin type III domain" name="fn3">
          <entry ac="IPR003961" desc="Fibronectin type III" name="FN3_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005515" name="protein binding"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6348" name="phosphate acquisition"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
          </entry>
          <signature-library-release library="PFAM" version="34.0"/>
        </signature>
        <model-ac>PF00041</model-ac>
        <locations>
          <hmmer3-location env-end="3843" env-start="3759" post-processed="true" score="43.4" evalue="3.1E-11" hmm-start="1" hmm-end="82" hmm-length="85" hmm-bounds="N_TERMINAL_COMPLETE" start="3759" end="3840">
            <location-fragments>
              <hmmer3-location-fragment start="3759" end="3840" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="3.0E-120" score="403.4">
        <signature ac="G3DSA:1.10.510.10" name="Transferase(Phosphotransferase) domain 1">
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>4bkyA00</model-ac>
        <locations>
          <hmmer3-location env-end="4209" env-start="3900" post-processed="true" score="197.1" evalue="1.6E-57" hmm-start="10" hmm-end="269" hmm-length="347" hmm-bounds="COMPLETE" start="3900" end="4209">
            <location-fragments>
              <hmmer3-location-fragment start="3900" end="4209" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="0.0" score="1218.7">
        <signature ac="G3DSA:2.60.40.10" name="Immunoglobulins">
          <entry ac="IPR013783" desc="Immunoglobulin-like fold" name="Ig-like_fold" type="HOMOLOGOUS_SUPERFAMILY">
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-7465" name="3,3'-thiodipropanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="MetaCyc" id="PWY-6807" name="xyloglucan degradation II (exoglucanase)"/>
            <pathway-xref db="Reactome" id="R-HSA-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8228" name="Porphyromonas gingivalis O-LPS antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-76009" name="Platelet Aggregation (Plug Formation)"/>
            <pathway-xref db="MetaCyc" id="PWY-7881" name="virginiae butanolide type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7745" name="p-HBAD biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6368" name="3-phosphoinositide degradation"/>
            <pathway-xref db="Reactome" id="R-MTU-868688" name="Trehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-3656253" name="Defective EXT1 causes exostoses 1, TRPS2 and CHDS"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-6352" name="3-phosphoinositide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="MetaCyc" id="PWY-7448" name="galloylated catechin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="MetaCyc" id="PWY-5784" name="indole-3-acetate inactivation VIII"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7119" name="ceramide and sphingolipid recycling and degradation (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-6297" name="tuberonate glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-MMU-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="MetaCyc" id="PWY-5793" name="maysin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-7565" name="aspyridone A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7252" name="luteolinidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7689" name="8-O-methylfusarubin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6051" name="2,4,6-trinitrotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-BTA-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7280" name="ternatin C3 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6027" name="capsiconiate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="MetaCyc" id="PWY-6827" name="gellan degradation"/>
            <pathway-xref db="Reactome" id="R-DME-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8116" name="ochratoxin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210991" name="Basigin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8081" name="leucine-derived hydroxynitrile glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7025" name="gentamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083633" name="Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"/>
            <pathway-xref db="Reactome" id="R-DME-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="MetaCyc" id="PWY-7461" name="hydroxycinnamate sugar acid ester biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-SSC-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8012" name="mupirocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7679" name="anthocyanidin acylglucoside and acylsambubioside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6958" name="icosapentaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7688" name="dTDP-alpha-D-ravidosamine and dTDP-4-acetyl-alpha-D-ravidosamine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8151" name="cholesterol degradation to androstenedione III (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="MetaCyc" id="PWY-7057" name="cichoriin interconversion"/>
            <pathway-xref db="MetaCyc" id="PWY-8208" name="Salmonella enterica serotype O:6,7 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7816" name="poly(ribitol phosphate) wall teichoic acid biosynthesis II (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-6365" name="D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8233" name="Escherichia coli serotype O:169 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-6442" name="spermidine hydroxycinnamic acid conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-MMU-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-CFA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="MetaCyc" id="PWY-7986" name="anguibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6002" name="lotaustralin degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="MetaCyc" id="PWY-5461" name="betanidin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9610379" name="HCMV Late Events"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-641" name="proanthocyanidins biosynthesis from flavanols"/>
            <pathway-xref db="MetaCyc" id="PWY-8231" name="Escherichia coli serotype O:127 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-RNO-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6036" name="cardenolide glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-HSA-977225" name="Amyloid fiber formation"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5176" name="coumarin biosynthesis (via 2-coumarate)"/>
            <pathway-xref db="Reactome" id="R-MMU-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7456" name="beta-(1,4)-mannan degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7246" name="pectin degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6821" name="kappa-carrageenan degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-1961" name="indole-3-acetate inactivation I"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8282" name="adenosylcobinamide-GDP salvage from assorted adenosylcobamides"/>
            <pathway-xref db="Reactome" id="R-DME-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="MetaCyc" id="PWY-7647" name="ulvan degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-RNO-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-CFA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-DME-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="MetaCyc" id="PWY-8058" name="2-deoxy-D-ribose degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5936" name="xyloglucan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7140" name="myricetin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-913709" name="O-linked glycosylation of mucins"/>
            <pathway-xref db="Reactome" id="R-RNO-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-CEL-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-3560783" name="Defective B4GALT7 causes EDS, progeroid type"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6525" name="stellariose and mediose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-822" name="fructan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5821" name="dalcochinin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-164940" name="Nef mediated downregulation of MHC class I complex cell surface expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7143" name="kaempferol gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-MMU-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="MetaCyc" id="PWY-6737" name="starch degradation V"/>
            <pathway-xref db="Reactome" id="R-HSA-5083635" name="Defective B3GALTL causes Peters-plus syndrome (PpS)"/>
            <pathway-xref db="Reactome" id="R-MMU-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-RNO-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-8119" name="microcin B17 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7694" name="zwittermicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DRE-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7599" name="anditomin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7401" name="crotonate fermentation (to acetate and cyclohexane carboxylate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5774" name="saponin biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214416" name="Phosphorylated REL is cleaved by and dissociates from DREDD"/>
            <pathway-xref db="MetaCyc" id="PWY-5268" name="salvianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7692" name="bikaverin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-6379" name="alcaligin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6720" name="toyocamycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7405" name="aurachin RE biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="MetaCyc" id="PWY-7633" name="calycosin 7-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7984" name="acinetobactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8235" name="Escherichia coli serotype O:21/Salmonella enterica serotype O:38 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6802" name="salidroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7238" name="sucrose biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-8053" name="anandamide biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-RNO-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-7612" name="chaetoglobosin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="MetaCyc" id="PWY-6749" name="CMP-legionaminate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="MetaCyc" id="PWY-5399" name="betacyanin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5265" name="peptidoglycan biosynthesis II (staphylococci)"/>
            <pathway-xref db="MetaCyc" id="PWY-7981" name="alpha-dystroglycan glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7256" name="cyanidin diglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7134" name="rutin degradation (plants)"/>
            <pathway-xref db="Reactome" id="R-MMU-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9012546" name="Interleukin-18 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-7982" name="pinoresinol degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-8964038" name="LDL clearance"/>
            <pathway-xref db="Reactome" id="R-RNO-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CFA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5975" name="furaneol and mesifurane biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="MetaCyc" id="PWY-8082" name="glycine lipid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8220" name="Escherichia coli serotype O:117 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7726" name="(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7954" name="tabtoxinine-beta-lactam biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-SSC-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SSC-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DDI-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7653" name="griseofulvin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4801" name="aloesone biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-HSA-447041" name="CHL1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-8257" name="Escherichia coli serotype O:52 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-DME-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-84" name="resveratrol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-RNO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8250" name="Escherichia coli serotype O:9 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8222" name="Escherichia coli serotype O:128 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7002" name="4-hydroxyacetophenone degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-844456" name="The NLRP3 inflammasome"/>
            <pathway-xref db="MetaCyc" id="PWY-8243" name="colanic acid (Escherichia coli K12) biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2029481" name="FCGR activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8045" name="cylindrospermopsin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-83" name="monolignol glucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7740" name="beta-D-mannosyl phosphomycoketide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DRE-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7530" name="Escherichia coli serotype O:104 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7463" name="N-methylanthraniloyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664323" name="FCGR3A-mediated IL10 synthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-1300645" name="Acrosome Reaction and Sperm:Oocyte Membrane Binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7318" name="dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6906" name="chitin derivatives degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6310" name="aloesone biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7191" name="kaempferol diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="MetaCyc" id="PWY-7815" name="poly(ribitol phosphate) wall teichoic acid biosynthesis I (B. subtilis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013508" name="NOTCH3 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="MetaCyc" id="PWY-5466" name="matairesinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-110478" name="Insulin signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7583" name="arachidonate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669934" name="Sunitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-81" name="toluene degradation to benzoyl-CoA (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-HSA-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7071" name="steviol glucoside biosynthesis (rebaudioside A biosynthesis)"/>
            <pathway-xref db="Reactome" id="R-DME-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-RNO-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5976" name="dhurrin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="MetaCyc" id="PWY-7055" name="daphnetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7458" name="violdelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-MMU-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-434131" name="NFkB activation mediated by RIP1 complexed with activated TLR3"/>
            <pathway-xref db="MetaCyc" id="PWY-7821" name="tunicamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SSC-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6686" name="mannosylglucosylglycerate biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-DRE-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7818" name="type IV lipoteichoic acid biosynthesis (S. pneumoniae)"/>
            <pathway-xref db="MetaCyc" id="PWY-7983" name="pseudomonine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5400" name="amaranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-CEL-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-MMU-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-GGA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7192" name="quercetin diglycoside biosynthesis (pollen-specific)"/>
            <pathway-xref db="Reactome" id="R-MMU-449836" name="Other interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6724" name="starch degradation II"/>
            <pathway-xref db="Reactome" id="R-HSA-8853338" name="Signaling by FGFR3 point mutants in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-5635838" name="Activation of SMO"/>
            <pathway-xref db="MetaCyc" id="PWY-6378" name="putrebactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-SSC-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2586552" name="Signaling by Leptin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-8983711" name="OAS antiviral response"/>
            <pathway-xref db="MetaCyc" id="PWY-8047" name="bryostatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1306955" name="GRB7 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8133" name="succinoglycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8252" name="Escherichia coli serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-761" name="rhizobactin 1021 biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7212" name="baicalein metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CFA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5619070" name="Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"/>
            <pathway-xref db="Reactome" id="R-HSA-9637628" name="Modulation by Mtb of host immune system"/>
            <pathway-xref db="Reactome" id="R-HSA-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8157" name="avenanthramide biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7050" name="icosapentaenoate biosynthesis IV (bacteria)"/>
            <pathway-xref db="Reactome" id="R-MMU-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9660826" name="Purinergic signaling in leishmaniasis infection"/>
            <pathway-xref db="Reactome" id="R-HSA-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7708" name="lyngbyatoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7946" name="sarcinaxanthin diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2206302" name="MPS I - Hurler syndrome"/>
            <pathway-xref db="Reactome" id="R-RNO-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-DME-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5160" name="rose anthocyanin biosynthesis I (via cyanidin 5-O-beta-D-glucoside)"/>
            <pathway-xref db="Reactome" id="R-HSA-428543" name="Inactivation of CDC42 and RAC1"/>
            <pathway-xref db="MetaCyc" id="PWY-6731" name="starch degradation III"/>
            <pathway-xref db="MetaCyc" id="PWY-7819" name="poly(3-O-beta-D-glucopyranosyl-N-acetylgalactosamine 1-phosphate) wall teichoic acid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-MMU-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7168" name="flavonol acylglucoside biosynthesis I - kaempferol derivatives"/>
            <pathway-xref db="MetaCyc" id="PWY-7623" name="astaxanthin dirhamnoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7743" name="dimycocerosyl triglycosyl phenolphthiocerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7913" name="firefly bioluminescence"/>
            <pathway-xref db="Reactome" id="R-MMU-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-GGA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-GGA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="MetaCyc" id="PWY-7450" name="anthocyanidin modification (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-5926" name="afrormosin conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-MMU-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7656" name="Spodoptera littoralis pheromone biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7811" name="6-methylpretetramide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7730" name="T-2 toxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-HSA-8866654" name="E3 ubiquitin ligases ubiquitinate target proteins"/>
            <pathway-xref db="Reactome" id="R-XTR-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-RNO-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7838" name="globo-series glycosphingolipids biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-CFA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5321" name="quercetin glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="MetaCyc" id="PWY-8143" name="L-ascorbate biosynthesis VII (plants, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-7824" name="prunasin and amygdalin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7606" name="docosahexaenoate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-8049" name="pederin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7695" name="aurofusarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-977068" name="Termination of O-glycan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5756" name="saponin biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9014826" name="Interleukin-36 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7419" name="FR-900098 and FR-33289 antibiotics biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5161" name="6'-deoxychalcone metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-2343" name="daidzein conjugates interconversion"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="MetaCyc" id="PWY-6546" name="brassinosteroids inactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="MetaCyc" id="PWY-8221" name="Escherichia coli serotype O:111/Salmonella enterica serotype O:35 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6373" name="acrylate degradation I"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7171" name="flavonol acylglucoside biosynthesis II - isorhamnetin derivatives"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="MetaCyc" id="PWY-7728" name="(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-7487" name="(+)-secoisolariciresinol diglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="MetaCyc" id="PWY-7592" name="arachidonate biosynthesis III (6-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-HSA-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="MetaCyc" id="PWY-7092" name="neolinustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SPO-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8877330" name="RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)"/>
            <pathway-xref db="Reactome" id="R-RNO-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-2901" name="cytokinins 9-N-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="MetaCyc" id="PWY-7712" name="deoxynivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8022" name="salmochelin degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6363" name="D-myo-inositol (1,4,5)-trisphosphate degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8035" name="streptovaricin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-HSA-2206292" name="MPS VII - Sly syndrome"/>
            <pathway-xref db="Reactome" id="R-MMU-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7822" name="chitin degradation III (Serratia)"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="MetaCyc" id="PWY-8218" name="Escherichia coli serotype O:56 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7532" name="acetylaszonalenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-CFA-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6658" name="acetan biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7261" name="anthocyanidin 3-malylglucoside biosynthesis (acyl-glucose dependent)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CFA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-6056" name="dimethylsulfoniopropanoate degradation II (cleavage)"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5688849" name="Defective CSF2RB causes SMDP5"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6397" name="mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8249" name="xanthommatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-SSC-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5710" name="capsaicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-7473" name="avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000157" name="Laminin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7716" name="penicillin G and penicillin V biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7475" name="des-methyl avenacin A-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-MMU-9664873" name="Pexophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-5286" name="anthocyanidin sophoroside metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6624" name="salicylate glucosides biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-HSA-2022923" name="Dermatan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-5473" name="hydroxycinnamic acid serotonin amides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DME-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-GGA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7100" name="spinosyn A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7214" name="baicalein degradation (hydrogen peroxide detoxification)"/>
            <pathway-xref db="MetaCyc" id="PWY-6672" name="cis-geranyl-CoA degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6722" name="candicidin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6148" name="tetrahydromethanopterin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6366" name="D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3595177" name="Defective CHSY1 causes TPBS"/>
            <pathway-xref db="Reactome" id="R-HSA-2243919" name="Crosslinking of collagen fibrils"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-7670" name="fusaridione A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6991" name="(-)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8207" name="Escherichia coli serotype O:85/Salmonella enterica serotype O:17 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-9609523" name="Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-5307" name="gentiodelphin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-HSA-9615017" name="FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"/>
            <pathway-xref db="Reactome" id="R-HSA-174577" name="Activation of C3 and C5"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3560801" name="Defective B3GAT3 causes JDSSDHD"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7375" name="mRNA capping I"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7213" name="wogonin metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-RNO-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-209394" name="Transcriptional activtion and repression of REL-68 target genes"/>
            <pathway-xref db="Reactome" id="R-RNO-3000157" name="Laminin interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5173214" name="O-glycosylation of TSR domain-containing proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-GGA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="MetaCyc" id="PWY-8032" name="chloramphenicol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6990" name="(+)-camphor biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-MMU-1236978" name="Cross-presentation of soluble exogenous antigens (endosomes)"/>
            <pathway-xref db="Reactome" id="R-GGA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="MetaCyc" id="PWY-7987" name="vanchrobactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="MetaCyc" id="PWY-2881" name="cytokinins 7-N-glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7018" name="paromomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="Reactome" id="R-CFA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7930" name="pyoluteorin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-8244" name="Escherichia coli serotype O:177 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-8232" name="Shigella boydii serotype 6 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7817" name="type I lipoteichoic acid biosynthesis (S. aureus)"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="MetaCyc" id="PWY-7885" name="phosphatidylinositol mannoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-2021" name="indole-3-acetate inactivation IV"/>
            <pathway-xref db="MetaCyc" id="PWY-8122" name="mycofactocin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-BTA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-CFA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6239" name="luteolin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-HSA-1483115" name="Hydrolysis of LPC"/>
            <pathway-xref db="MetaCyc" id="PWY-7464" name="cyanidin 3,7-diglucoside polyacylation biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-351906" name="Apoptotic cleavage of cell adhesion proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7878" name="A-factor gamma-butyrolactone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209406" name="Degradation of NF-kappa-B inhibitor, CACT"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7247" name="beta-D-glucuronide and D-glucuronate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-HSA-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-4421" name="curcumin glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7922" name="protein O-mannosylation II (mammals, core M1 and core M2)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="MetaCyc" id="PWY-5941" name="glycogen degradation II"/>
            <pathway-xref db="Reactome" id="R-MMU-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5342" name="ajugose biosynthesis I (galactinol-dependent)"/>
            <pathway-xref db="Reactome" id="R-MMU-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-HSA-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-214869" name="Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-6010" name="apigenin glycosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-SCE-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-DME-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198745" name="Signalling to STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-BTA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-HSA-1442490" name="Collagen degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8152" name="androstenedione degradation II (anaerobic)"/>
            <pathway-xref db="Reactome" id="R-HSA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9664565" name="Signaling by ERBB2 KD Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8253" name="Escherichia coli serotype O:149/Shigella boydii serotype O1 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7706" name="dapdiamides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8964046" name="VLDL clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-MMU-1462054" name="Alpha-defensins"/>
            <pathway-xref db="Reactome" id="R-BTA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5310" name="superpathway of anthocyanin biosynthesis (from delphinidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-SCE-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-HSA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-CFA-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="Reactome" id="R-HSA-2023837" name="Signaling by FGFR2 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9674404" name="Sorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8219" name="Escherichia coli serotype O:107 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9032500" name="Activated NTRK2 signals through FYN"/>
            <pathway-xref db="Reactome" id="R-HSA-5689603" name="UCH proteinases"/>
            <pathway-xref db="Reactome" id="R-MMU-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9702509" name="FLT3 mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-MMU-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-HSA-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-GGA-2132286" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6788" name="cellulose degradation II (fungi)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6385" name="peptidoglycan biosynthesis III (mycobacteria)"/>
            <pathway-xref db="Reactome" id="R-GGA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-214842" name="DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-SSC-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-MMU-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-MMU-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-5437" name="L-threonine degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-9034015" name="Signaling by NTRK3 (TRKC)"/>
            <pathway-xref db="Reactome" id="R-RNO-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-6032" name="digitoxigenin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-214411" name="REL binds to DREDD in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-DME-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6190" name="2,4-dichlorotoluene degradation"/>
            <pathway-xref db="Reactome" id="R-SSC-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6015" name="vitexin and derivatives biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-MMU-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="MetaCyc" id="PWY-7738" name="polyacyltrehalose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9026519" name="Activated NTRK2 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-CFA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="MetaCyc" id="PWY-8039" name="mitomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7711" name="calonectrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2151201" name="Transcriptional activation of mitochondrial biogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6948" name="sitosterol degradation to androstenedione"/>
            <pathway-xref db="Reactome" id="R-CFA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5083628" name="Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"/>
            <pathway-xref db="Reactome" id="R-CEL-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2033514" name="FGFR3 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-SSC-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6527" name="stachyose degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8040" name="ansatrienin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8272" name="Escherichia coli serotype O:49 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CFA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-CEL-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9664422" name="FCGR3A-mediated phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5313" name="superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside)"/>
            <pathway-xref db="Reactome" id="R-MMU-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-CEL-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7960" name="rhabduscin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7029" name="terminal olefins biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-MMU-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7150" name="polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-7151" name="polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)"/>
            <pathway-xref db="MetaCyc" id="PWY-5477" name="gallotannin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-MMU-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6415" name="L-ascorbate biosynthesis V (euglena, D-galacturonate pathway)"/>
            <pathway-xref db="MetaCyc" id="PWY-6679" name="jadomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-CFA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8055" name="palmitoyl ethanolamide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7354" name="aclacinomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-2132263" name="Creation of classical C3 convertase"/>
            <pathway-xref db="MetaCyc" id="PWY-8234" name="Escherichia coli serotype O:183/Shigella boydii serotype O:10 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7988" name="baumannoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8951664" name="Neddylation"/>
            <pathway-xref db="Reactome" id="R-RNO-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6657" name="polyhydroxydecanoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5632681" name="Ligand-receptor interactions"/>
            <pathway-xref db="Reactome" id="R-GGA-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702998" name="linifanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SSC-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674401" name="Sunitinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-CFA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="MetaCyc" id="PWY-862" name="fructan degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7714" name="harzianum A and trichodermin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5987" name="sorgoleone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7585" name="docosahexaenoate biosynthesis II (bacteria)"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-5353" name="arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2022090" name="Assembly of collagen fibrils and other multimeric structures"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7882" name="IM-2 type gamma-butyrolactones biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-1483152" name="Hydrolysis of LPE"/>
            <pathway-xref db="MetaCyc" id="PWY-8247" name="(Kdo)2-lipid A biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7950" name="diadinoxanthin and fucoxanthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7569" name="arginomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3214847" name="HATs acetylate histones"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6401" name="hispidol and hispidol 4'-O-beta-D-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-7863" name="roseoflavin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-RNO-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-BTA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5694530" name="Cargo concentration in the ER"/>
            <pathway-xref db="Reactome" id="R-RNO-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-173107" name="Binding and entry of HIV virion"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1901" name="aurone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-RNO-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CFA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7531" name="mannojirimycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6944" name="androstenedione degradation I (aerobic)"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7561" name="tenellin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-264876" name="Insulin processing"/>
            <pathway-xref db="Reactome" id="R-HSA-9035034" name="RHOF GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7135" name="emetine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7690" name="holomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-193692" name="Regulated proteolysis of p75NTR"/>
            <pathway-xref db="MetaCyc" id="PWY-5660" name="taxol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7696" name="citreoisocoumarin and bikisocoumarin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7437" name="protein O-[N-acetyl]-glucosylation"/>
            <pathway-xref db="MetaCyc" id="PWY-7491" name="podophyllotoxin glucosides metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6673" name="caffeoylglucarate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6799" name="fatty acid biosynthesis initiation (plant mitochondria)"/>
            <pathway-xref db="MetaCyc" id="PWY-7658" name="protein N-glycosylation (Methanococcus voltae)"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-DRE-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-5794" name="malonate degradation I (biotin-independent)"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-CEL-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-DME-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="MetaCyc" id="PWY-4702" name="phytate degradation I"/>
            <pathway-xref db="Reactome" id="R-HSA-3595172" name="Defective CHST3 causes SEDCJD"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8166" name="emodin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-5343" name="ajugose biosynthesis II (galactinol-independent)"/>
            <pathway-xref db="MetaCyc" id="PWY-7702" name="sch210971 and sch210972 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-XTR-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-1474244" name="Extracellular matrix organization"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5658623" name="FGFRL1 modulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7452" name="cyanidin dimalonylglucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5679" name="clavulanate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="MetaCyc" id="PWY-5491" name="diethylphosphate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="MetaCyc" id="PWY-7265" name="lampranthin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7474" name="avenacin A-2 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-448706" name="Interleukin-1 processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8849932" name="Synaptic adhesion-like molecules"/>
            <pathway-xref db="MetaCyc" id="PWY-6784" name="cellulose and hemicellulose degradation (cellulolosome)"/>
            <pathway-xref db="Reactome" id="R-HSA-2022870" name="Chondroitin sulfate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7577" name="ferrichrome biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7907" name="(2S,3E)-2-amino-4-methoxy-but-3-enoate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="MetaCyc" id="PWY-5994" name="palmitate biosynthesis I (type I fatty acid synthase)"/>
            <pathway-xref db="Reactome" id="R-RNO-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1236977" name="Endosomal/Vacuolar pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-RNO-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7468" name="benzoyl-beta-D-glucopyranose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="MetaCyc" id="PWY-5284" name="shisonin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6848" name="rutin degradation"/>
            <pathway-xref db="Reactome" id="R-DME-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-HSA-350054" name="Notch-HLH transcription pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3595174" name="Defective CHST14 causes EDS, musculocontractural type"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="MetaCyc" id="PWY-7661" name="protein N-glycosylation (Haloferax volcanii)"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-GGA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-5822" name="trichloroethene degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-8036" name="chaxamycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="MetaCyc" id="PWY-7897" name="flavonoid di-C-glucosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="MetaCyc" id="PWY-7145" name="genistin gentiobioside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8205" name="Escherichia coli serotype O:77/Salmonella enterica serotype O:6,14 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7602" name="icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"/>
            <pathway-xref db="MetaCyc" id="PWY-8204" name="Salmonella enterica serotype O:54 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="Reactome" id="R-RNO-166663" name="Initial triggering of complement"/>
            <pathway-xref db="MetaCyc" id="PWY-6627" name="salinosporamide A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-447038" name="NrCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-8224" name="Escherichia coli serotype O:157/Salmonella enterica serotype O:30 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-MMU-210500" name="Glutamate Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-8941856" name="RUNX3 regulates NOTCH signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5800" name="xylan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-CFA-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-4420332" name="Defective B3GALT6 causes EDSP2 and SEMDJL1"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7157" name="eupatolitin 3-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="Reactome" id="R-CEL-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-5339" name="chalcone 2'-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-376176" name="Signaling by ROBO receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-CFA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-HSA-2022854" name="Keratan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-CFA-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6320" name="phaselate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CFA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="MetaCyc" id="PWY-6946" name="cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6575" name="juvenile hormone III biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-7058" name="esculetin modification"/>
            <pathway-xref db="MetaCyc" id="PWY-7445" name="luteolin triglucuronide degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-5338" name="galactosylcyclitol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6279" name="myxol-2' fucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5607763" name="CLEC7A (Dectin-1) induces NFAT activation"/>
            <pathway-xref db="Reactome" id="R-CEL-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-416700" name="Other semaphorin interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-7352" name="daunorubicin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7449" name="acylated cyanidin galactoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="MetaCyc" id="PWY-5094" name="naringenin glycoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8176" name="geraniol biosynthesis (cytosol)"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5475" name="pentagalloylglucose biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7669" name="equisetin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6470" name="peptidoglycan biosynthesis V (beta-lactam resistance)"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-MMU-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-HSA-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7659" name="viridicatumtoxin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-187024" name="NGF-independant TRKA activation"/>
            <pathway-xref db="Reactome" id="R-RNO-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-428540" name="Activation of RAC1"/>
            <pathway-xref db="Reactome" id="R-RNO-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-SSC-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702624" name="sorafenib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DME-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2160916" name="Hyaluronan uptake and degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-182218" name="Nef Mediated CD8 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-HSA-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7979" name="protein O-mannosylation III (mammals, core M3)"/>
            <pathway-xref db="Reactome" id="R-MMU-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-HSA-9674428" name="PDGFR mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-GGA-373920" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7382" name="lipoate biosynthesis and incorporation IV (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7460" name="2-O-acetyl-3-O-trans-coutarate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-MMU-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-HSA-8857538" name="PTK6 promotes HIF1A stabilization"/>
            <pathway-xref db="MetaCyc" id="PWY-5835" name="geranyl acetate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5083629" name="Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"/>
            <pathway-xref db="MetaCyc" id="PWY-7693" name="guadinomine B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9674403" name="Regorafenib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-173736" name="Alternative complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8248" name="lipid A-core biosynthesis (P. gingivalis)"/>
            <pathway-xref db="Reactome" id="R-HSA-9669921" name="KIT mutants bind TKIs"/>
            <pathway-xref db="Reactome" id="R-DME-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9028335" name="Activated NTRK2 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-HSA-166058" name="MyD88:MAL(TIRAP) cascade initiated on plasma membrane"/>
            <pathway-xref db="MetaCyc" id="PWY-7672" name="fusaric acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7529" name="CMP-N-acetyl-7-O-acetylneuraminate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="MetaCyc" id="PWY-6362" name="1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"/>
            <pathway-xref db="Reactome" id="R-HSA-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="MetaCyc" id="PWY-8075" name="(Kdo)2-lipid A biosynthesis (P. putida)"/>
            <pathway-xref db="Reactome" id="R-RNO-879415" name="Advanced glycosylation endproduct receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-RNO-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-HSA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-DRE-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6322" name="phosphinothricin tripeptide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-MMU-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-193634" name="Axonal growth inhibition (RHOA activation)"/>
            <pathway-xref db="Reactome" id="R-RNO-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="MetaCyc" id="PWY-6623" name="salicylate glucosides biosynthesis II"/>
            <pathway-xref db="Reactome" id="R-CFA-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-RNO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-163125" name="Post-translational modification: synthesis of GPI-anchored proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-1632852" name="Macroautophagy"/>
            <pathway-xref db="MetaCyc" id="PWY-3121" name="linamarin degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2197563" name="NOTCH2 intracellular domain regulates transcription"/>
            <pathway-xref db="Reactome" id="R-CFA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-MMU-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="MetaCyc" id="PWY-7735" name="echinomycin and triostin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7621" name="autoinducer CAI-1 biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-DME-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="MetaCyc" id="PWY-8251" name="Escherichia coli serotype O:2 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9680187" name="Signaling by extracellular domain mutants of KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-6364" name="D-myo-inositol (1,3,4)-trisphosphate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673770" name="Signaling by PDGFRA extracellular domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-DME-209968" name="Thyroxine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7563" name="bassianin and desmethylbassianin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5223345" name="Miscellaneous transport and binding events"/>
            <pathway-xref db="Reactome" id="R-RNO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="MetaCyc" id="PWY-5846" name="colchicine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3656243" name="Defective ST3GAL3 causes MCT12 and EIEE15"/>
            <pathway-xref db="MetaCyc" id="PWY-7883" name="anhydromuropeptides recycling II"/>
            <pathway-xref db="Reactome" id="R-HSA-2129379" name="Molecules associated with elastic fibres"/>
            <pathway-xref db="Reactome" id="R-MMU-8853383" name="Lysosomal oligosaccharide catabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5655253" name="Signaling by FGFR2 in disease"/>
            <pathway-xref db="Reactome" id="R-DME-209400" name="Transcriptional activtion by phosphorylated DL/DIF dimer"/>
            <pathway-xref db="Reactome" id="R-MMU-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-HSA-5140745" name="WNT5A-dependent internalization of FZD2, FZD5 and ROR2"/>
            <pathway-xref db="Reactome" id="R-CEL-1650814" name="Collagen biosynthesis and modifying enzymes"/>
            <pathway-xref db="Reactome" id="R-DRE-418990" name="Adherens junctions interactions"/>
            <pathway-xref db="Reactome" id="R-DME-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6735" name="starch degradation IV"/>
            <pathway-xref db="Reactome" id="R-HSA-418886" name="Netrin mediated repulsion signals"/>
            <pathway-xref db="Reactome" id="R-RNO-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-180534" name="Vpu mediated degradation of CD4"/>
            <pathway-xref db="Reactome" id="R-CEL-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5683826" name="Surfactant metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-6762" name="salicylate glucosides biosynthesis IV"/>
            <pathway-xref db="Reactome" id="R-MMU-5684264" name="MAP3K8 (TPL2)-dependent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-917977" name="Transferrin endocytosis and recycling"/>
            <pathway-xref db="MetaCyc" id="PWY-6453" name="stigma estolide biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-CEL-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6024" name="isovitexin glycosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8242" name="Escherichia coli serotype O:51/Salmonella enterica serotype O:57 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-SCE-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-9025046" name="NTF3 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-381426" name="Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"/>
            <pathway-xref db="Reactome" id="R-MMU-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-MMU-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="MetaCyc" id="PWY-7049" name="icosapentaenoate biosynthesis II (6-desaturase, mammals)"/>
            <pathway-xref db="MetaCyc" id="PWY-2661" name="trehalose biosynthesis V"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9664873" name="Pexophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6902" name="chitin degradation II (Vibrio)"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="MetaCyc" id="PWY-5320" name="kaempferol glycoside biosynthesis (Arabidopsis)"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-264642" name="Acetylcholine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-MMU-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-RNO-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-181430" name="Norepinephrine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="MetaCyc" id="PWY-7109" name="megalomicin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-CEL-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="MetaCyc" id="PWY-7547" name="prodigiosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6842" name="glutathione-mediated detoxification II"/>
            <pathway-xref db="Reactome" id="R-GGA-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-RNO-388841" name="Costimulation by the CD28 family"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-140834" name="Extrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="MetaCyc" id="PWY-6407" name="yersiniabactin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6855" name="chitin degradation I (archaea)"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-1921" name="indole-3-acetate activation II"/>
            <pathway-xref db="MetaCyc" id="PWY-7186" name="superpathway of scopolin and esculin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-5903" name="bacillibactin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="MetaCyc" id="PWY-6945" name="cholesterol degradation to androstenedione I (cholesterol oxidase)"/>
            <pathway-xref db="Reactome" id="R-RNO-173736" name="Alternative complement activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6972" name="oleandomycin activation/inactivation"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7091" name="linustatin bioactivation"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7945" name="2,2'-bis-(4-hydroxy-3-methybut-2-enyl)-beta,beta-carotene monoglucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7409" name="phospholipid remodeling (phosphatidylethanolamine, yeast)"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-MMU-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DRE-983168" name="Antigen processing: Ubiquitination &amp; Proteasome degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7713" name="nivalenol biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7412" name="mycinamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948216" name="Collagen chain trimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-8985586" name="SLIT2:ROBO1 increases RHOA activity"/>
            <pathway-xref db="Reactome" id="R-HSA-140875" name="Common Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-8209" name="Escherichia coli serotype O:15 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7884" name="lipoprotein posttranslational modification"/>
            <pathway-xref db="Reactome" id="R-MMU-140837" name="Intrinsic Pathway of Fibrin Clot Formation"/>
            <pathway-xref db="MetaCyc" id="PWY-7746" name="mycobacterial sulfolipid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-7053" name="docosahexaenoate biosynthesis I (lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-114608" name="Platelet degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3656237" name="Defective EXT2 causes exostoses 2"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="MetaCyc" id="PWY-8217" name="Escherichia coli serotype O:55/Salmonella enterica serotype O:50 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8206" name="Salmonella enterica serotype O:18 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="MetaCyc" id="PWY-7570" name="blasticidin S biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5984" name="rifamycin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-420597" name="Nectin/Necl trans heterodimerization"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="MetaCyc" id="PWY-7407" name="aurachin A, B, C and D biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-8851680" name="Butyrophilin (BTN) family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="MetaCyc" id="PWY-5067" name="glycogen biosynthesis II (from UDP-D-Glucose)"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-GGA-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-CFA-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-BTA-1236974" name="ER-Phagosome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-210744" name="Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"/>
            <pathway-xref db="MetaCyc" id="PWY-7677" name="rosamicin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-7253" name="apigeninidin 5-O-glucoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6996" name="daidzin and daidzein degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8985801" name="Regulation of cortical dendrite branching"/>
            <pathway-xref db="Reactome" id="R-MMU-1855204" name="Synthesis of IP3 and IP4 in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-5797" name="indole-3-acetate inactivation VI"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-166663" name="Initial triggering of complement"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-451927" name="Interleukin-2 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8939247" name="RUNX1 regulates transcription of genes involved in interleukin signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7624" name="nystatin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-CEL-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-433692" name="Proton-coupled monocarboxylate transport"/>
            <pathway-xref db="MetaCyc" id="PWY-8212" name="Escherichia coli serotype O:8 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5688890" name="Defective CSF2RA causes SMDP4"/>
            <pathway-xref db="MetaCyc" id="PWY-5379" name="B series fagopyritols biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7037" name="protein O-glycosylation (Neisseria)"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6314" name="plumbagin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-7940" name="lauryl-hydroxychlorobactene glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5672" name="ginsenosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7139" name="sesaminol glucoside biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6039" name="chlorogenic acid biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="MetaCyc" id="PWY-6763" name="salicortin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-6346" name="staurosporine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8210" name="pyrrolomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="MetaCyc" id="PWY-5292" name="vindoline, vindorosine and vinblastine biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7555" name="alpha-cyclopiazonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8241" name="Escherichia coli serotype O:71/Salmonella enterica serotype O:28ac O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-MMU-9010553" name="Regulation of expression of SLITs and ROBOs"/>
            <pathway-xref db="Reactome" id="R-HSA-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6471" name="peptidoglycan biosynthesis IV (Enterococcus faecium)"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DME-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-6312" name="barbaloin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-1971475" name="A tetrasaccharide linker sequence is required for GAG synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7673" name="fusarin C biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-3785653" name="Myoclonic epilepsy of Lafora"/>
            <pathway-xref db="Reactome" id="R-HSA-2025928" name="Calcineurin activates NFAT"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="MetaCyc" id="PWY-6717" name="(1,4)-beta-D-xylan degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-70268" name="Pyruvate metabolism"/>
            <pathway-xref db="MetaCyc" id="PWY-5875" name="staphyloxanthin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-4922" name="6-methoxymellein biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6316" name="aromatic polyketides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7859" name="jasmonoyl-L-isoleucine inactivation"/>
            <pathway-xref db="MetaCyc" id="PWYG-321" name="mycolate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8084" name="daurichromenate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-6922" name="L-Ndelta-acetylornithine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6824" name="justicidin B biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-196108" name="Pregnenolone biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="MetaCyc" id="PWY-2902" name="cytokinin-O-glucosides biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8000" name="vitamin K degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-HSA-2022928" name="HS-GAG biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-2214320" name="Anchoring fibril formation"/>
            <pathway-xref db="MetaCyc" id="PWY-5048" name="rosmarinic acid biosynthesis I"/>
            <pathway-xref db="MetaCyc" id="PWY-5469" name="sesamin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7056" name="daphnin interconversion"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="MetaCyc" id="PWY-7687" name="stipitatate biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7074" name="phenylethanol glycoconjugate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-HSA-446107" name="Type I hemidesmosome assembly"/>
            <pathway-xref db="MetaCyc" id="PWY-6930" name="phenolic malonylglucosides biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-164939" name="Nef mediated downregulation of CD28 cell surface expression"/>
            <pathway-xref db="MetaCyc" id="PWY-5666" name="alpha-solanine/alpha-chaconine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7133" name="quercetin glucoside degradation (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-5312" name="superpathway of anthocyanin biosynthesis (from pelargonidin 3-O-glucoside)"/>
            <pathway-xref db="MetaCyc" id="PWY-7521" name="3-(4-sulfophenyl)butanoate degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-RNO-977606" name="Regulation of Complement cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-264876" name="Insulin processing"/>
            <pathway-xref db="MetaCyc" id="PWY-7543" name="5-N-acetylardeemin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SSC-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2132295" name="MHC class II antigen presentation"/>
            <pathway-xref db="Reactome" id="R-DME-419037" name="NCAM1 interactions"/>
            <pathway-xref db="MetaCyc" id="PWY-622" name="starch biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7660" name="tryptoquialanine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2122948" name="Activated NOTCH1 Transmits Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1566977" name="Fibronectin matrix formation"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="MetaCyc" id="PWY-7697" name="geranyl beta-primeveroside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7415" name="tylosin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-BTA-198933" name="Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="MetaCyc" id="PWY-8230" name="Salmonella enterica serotype O:13 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9619665" name="EGR2 and SOX10-mediated initiation of Schwann cell myelination"/>
            <pathway-xref db="MetaCyc" id="PWY-8211" name="Escherichia coli serotype O:7 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-418890" name="Role of second messengers in netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-RNO-983170" name="Antigen Presentation: Folding, assembly and peptide loading of class I MHC"/>
            <pathway-xref db="Reactome" id="R-HSA-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-HSA-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-8226" name="Escherichia coli serotype O:152 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-7470" name="phosphatidylcholine biosynthesis VII"/>
            <pathway-xref db="Reactome" id="R-HSA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-373756" name="SDK interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="MetaCyc" id="PWY-6655" name="xanthan biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2033515" name="t(4;14) translocations of FGFR3"/>
            <pathway-xref db="MetaCyc" id="PWY-6771" name="rhamnogalacturonan type I degradation II (bacteria)"/>
            <pathway-xref db="MetaCyc" id="PWY-5381" name="NAD salvage (plants)"/>
            <pathway-xref db="Reactome" id="R-HSA-2979096" name="NOTCH2 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-RNO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-114608" name="Platelet degranulation"/>
            <pathway-xref db="MetaCyc" id="PWY-7719" name="CMP-diacetamido-8-epilegionaminic acid biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5380" name="A series fagopyritols biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-3134963" name="DEx/H-box helicases activate type I IFN and inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-RNO-210991" name="Basigin interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-DRE-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-DME-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-445095" name="Interaction between L1 and Ankyrins"/>
            <pathway-xref db="MetaCyc" id="PWY-361" name="phenylpropanoid biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8957275" name="Post-translational protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-7921" name="protein O-mannosylation I (yeast)"/>
            <pathway-xref db="MetaCyc" id="PWY-7166" name="kaempferide triglycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-HSA-9702620" name="quizartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-6809371" name="Formation of the cornified envelope"/>
            <pathway-xref db="Reactome" id="R-MMU-5660668" name="CLEC7A/inflammasome pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-MMU-9696273" name="RND1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-1981" name="indole-3-acetate inactivation III"/>
            <pathway-xref db="Reactome" id="R-HSA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-842" name="starch degradation I"/>
            <pathway-xref db="Reactome" id="R-RNO-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7129" name="quercetin glucoside biosynthesis (Allium)"/>
            <pathway-xref db="Reactome" id="R-HSA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-3656225" name="Defective CHST6 causes MCDC1"/>
            <pathway-xref db="Reactome" id="R-GGA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CFA-2024096" name="HS-GAG degradation"/>
            <pathway-xref db="MetaCyc" id="PWY-7820" name="teichuronic acid biosynthesis (B. subtilis 168)"/>
            <pathway-xref db="MetaCyc" id="PWY-5397" name="crocetin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7671" name="saframycin A biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7989" name="acinetoferrin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3878781" name="Glycogen storage disease type IV (GBE1)"/>
            <pathway-xref db="Reactome" id="R-RNO-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="MetaCyc" id="PWY-6558" name="heparan sulfate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-MMU-173623" name="Classical antibody-mediated complement activation"/>
            <pathway-xref db="MetaCyc" id="PWY-8038" name="naphthomycin biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-7737" name="thiocoraline biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-5759" name="saponin biosynthesis III"/>
            <pathway-xref db="Reactome" id="R-RNO-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-375276" name="Peptide ligand-binding receptors"/>
            <pathway-xref db="Reactome" id="R-DME-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3322077" name="Glycogen synthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-8052" name="2-arachidonoylglycerol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3000178" name="ECM proteoglycans"/>
            <pathway-xref db="Reactome" id="R-RNO-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7601" name="arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"/>
            <pathway-xref db="Reactome" id="R-MMU-2168880" name="Scavenging of heme from plasma"/>
            <pathway-xref db="Reactome" id="R-MMU-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7172" name="flavonol acylglucoside biosynthesis III - quercetin derivatives"/>
            <pathway-xref db="Reactome" id="R-MMU-1855183" name="Synthesis of IP2, IP, and Ins in the cytosol"/>
            <pathway-xref db="MetaCyc" id="PWY-7771" name="butachlor degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-7045" name="mithramycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-BTA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-HSA-975634" name="Retinoid metabolism and transport"/>
            <pathway-xref db="Reactome" id="R-DME-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-181429" name="Serotonin Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8941413" name="Events associated with phagocytolytic activity of PMN cells"/>
            <pathway-xref db="Reactome" id="R-DRE-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656244" name="Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)"/>
            <pathway-xref db="Reactome" id="R-RNO-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-8851708" name="Signaling by FGFR2 IIIa TM"/>
            <pathway-xref db="Reactome" id="R-MMU-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-RNO-186763" name="Downstream signal transduction"/>
            <pathway-xref db="MetaCyc" id="PWY-7367" name="phosphatidylcholine resynthesis via glycerophosphocholine"/>
            <pathway-xref db="Reactome" id="R-MMU-166665" name="Terminal pathway of complement"/>
            <pathway-xref db="Reactome" id="R-SSC-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-419037" name="NCAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-SSC-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-RNO-9014843" name="Interleukin-33 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2024101" name="CS/DS degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7137" name="quercetin gentiotetraside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-3214841" name="PKMTs methylate histone lysines"/>
            <pathway-xref db="MetaCyc" id="PWY-8236" name="Salmonella enterica serotype O:39 O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7727" name="docosahexaenoate biosynthesis IV (4-desaturase, mammals)"/>
            <pathway-xref db="Reactome" id="R-RNO-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="MetaCyc" id="PWY-7900" name="glycogen biosynthesis III (from alpha-maltose 1-phosphate)"/>
            <pathway-xref db="MetaCyc" id="PWY-5105" name="hesperitin glycoside biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8853884" name="Transcriptional Regulation by VENTX"/>
            <pathway-xref db="Reactome" id="R-CEL-1474228" name="Degradation of the extracellular matrix"/>
            <pathway-xref db="Reactome" id="R-CFA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-447043" name="Neurofascin interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-HSA-977443" name="GABA receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2172127" name="DAP12 interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="MetaCyc" id="PWY-5139" name="pelargonidin conjugates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673767" name="Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-RNO-2022857" name="Keratan sulfate degradation"/>
            <pathway-xref db="Reactome" id="R-CFA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-8237" name="Escherichia coli serotype O:1B/Salmonella enterica serotype O:42 O antigen biosynthesis"/>
            <pathway-xref db="MetaCyc" id="PWY-6971" name="oleandomycin biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="MetaCyc" id="PWY-6456" name="serinol biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-SSC-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-5620916" name="VxPx cargo-targeting to cilium"/>
            <pathway-xref db="Reactome" id="R-MMU-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="MetaCyc" id="PWY-6920" name="6-gingerol analog biosynthesis (engineered)"/>
            <pathway-xref db="Reactome" id="R-DRE-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-373760" name="L1CAM interactions"/>
            <pathway-xref db="Reactome" id="R-DME-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-2894862" name="Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DME-373753" name="Nephrin family interactions"/>
          </entry>
          <signature-library-release library="GENE3D" version="4.3.0"/>
        </signature>
        <model-ac>3knbB00</model-ac>
        <locations>
          <hmmer3-location env-end="2616" env-start="2512" post-processed="true" score="64.8" evalue="2.6E-17" hmm-start="9" hmm-end="104" hmm-length="107" hmm-bounds="INCOMPLETE" start="2516" end="2615">
            <location-fragments>
              <hmmer3-location-fragment start="2516" end="2615" dc-status="CONTINUOUS"/>
            </location-fragments>
          </hmmer3-location>
        </locations>
      </hmmer3-match>
      <hmmer3-match evalue="1.5E-98" score="329.4">
        <signature ac="PF00069" desc="Protein kinase domain" name="Pkinase">
          <entry ac="IPR000719" desc="Protein kinase domain" name="Prot_kinase_dom" type="DOMAIN">
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0004672" name="protein kinase activity"/>
            <go-xref category="MOLECULAR_FUNCTION" db="GO" id="GO:0005524" name="ATP binding"/>
            <go-xref category="BIOLOGICAL_PROCESS" db="GO" id="GO:0006468" name="protein phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-MMU-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-CEL-6804116" name="TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-DME-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-MMU-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DRE-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-HSA-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-CEL-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-68911" name="G2 Phase"/>
            <pathway-xref db="Reactome" id="R-MMU-1502540" name="Signaling by Activin"/>
            <pathway-xref db="Reactome" id="R-DME-209461" name="Ubiquitination and degradation of phosphorylated ARM"/>
            <pathway-xref db="Reactome" id="R-RNO-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-SPO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DDI-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9649948" name="Signaling downstream of RAS mutants"/>
            <pathway-xref db="Reactome" id="R-DME-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-CEL-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-RNO-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-DRE-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-XTR-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-RNO-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-DDI-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-8853336" name="Signaling by plasma membrane FGFR1 fusions"/>
            <pathway-xref db="Reactome" id="R-SSC-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-RNO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9617324" name="Negative regulation of NMDA receptor-mediated neuronal transmission"/>
            <pathway-xref db="Reactome" id="R-MMU-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-CFA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-HSA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-DDI-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-RNO-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-RNO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DRE-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-DME-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-DME-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-DRE-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-CEL-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-SPO-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-RNO-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-GGA-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-DME-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-SPO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-SSC-8849470" name="PTK6 Regulates Cell Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-CEL-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9026357" name="NTF4 activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-HSA-9703465" name="Signaling by FLT3 fusion proteins"/>
            <pathway-xref db="Reactome" id="R-MMU-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-SCE-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-CEL-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-DRE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-GGA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-BTA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-HSA-9669914" name="Dasatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-DME-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-CEL-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-MMU-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-CEL-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DME-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-DRE-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9632700" name="Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6"/>
            <pathway-xref db="Reactome" id="R-RNO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-RNO-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-SCE-202670" name="ERKs are inactivated"/>
            <pathway-xref db="Reactome" id="R-SPO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DME-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8849468" name="PTK6 Regulates Proteins Involved in RNA Processing"/>
            <pathway-xref db="Reactome" id="R-HSA-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-350376" name="Activation of RAC1:GTP by FZ:DSH complex"/>
            <pathway-xref db="Reactome" id="R-RNO-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DME-214399" name="Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-3645790" name="TGFBR2 Kinase Domain Mutants in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-168138" name="Toll Like Receptor 9 (TLR9) Cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-MMU-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-SPO-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-CEL-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-MMU-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="MetaCyc" id="PWY-6955" name="lincomycin A biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-HSA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-RNO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DDI-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-HSA-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-DME-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-DRE-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-CEL-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-MMU-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-DME-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-CEL-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DRE-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-SPO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-RNO-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-BTA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-2173788" name="Downregulation of TGF-beta receptor signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-DME-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-CEL-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-HSA-9679191" name="Potential therapeutics for SARS"/>
            <pathway-xref db="Reactome" id="R-SSC-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SPO-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-CEL-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-MMU-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-RNO-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-DRE-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-442729" name="CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"/>
            <pathway-xref db="Reactome" id="R-DME-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-RNO-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-8849470" name="PTK6 Regulates Cell Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9665247" name="Resistance of ERBB2 KD mutants to osimertinib"/>
            <pathway-xref db="Reactome" id="R-CEL-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6811555" name="PI5P Regulates TP53 Acetylation"/>
            <pathway-xref db="Reactome" id="R-RNO-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-SPO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-CEL-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-RNO-1489509" name="DAG and IP3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-114516" name="Disinhibition of SNARE formation"/>
            <pathway-xref db="Reactome" id="R-DRE-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-HSA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CEL-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SCE-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-MMU-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-CEL-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-SPO-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-DME-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-SSC-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020956" name="Interleukin-27 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-5467337" name="APC truncation mutants have impaired AXIN binding"/>
            <pathway-xref db="Reactome" id="R-DME-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-8939211" name="ESR-mediated signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-SSC-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-GGA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SPO-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-DME-390178" name="DS ligand not bound to FT receptor"/>
            <pathway-xref db="Reactome" id="R-HSA-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-BTA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-DME-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-RNO-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-SSC-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-MMU-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-68877" name="Mitotic Prometaphase"/>
            <pathway-xref db="Reactome" id="R-MMU-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-MMU-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-RNO-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-390522" name="Striated Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DME-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SPO-1489509" name="DAG and IP3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-RNO-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-SCE-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-DME-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-SCE-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-CEL-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9652817" name="Signaling by MAPK mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-HSA-1989781" name="PPARA activates gene expression"/>
            <pathway-xref db="Reactome" id="R-DDI-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-DME-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-RNO-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5467348" name="Truncations of AMER1 destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DME-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CEL-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-GGA-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-HSA-9660537" name="Signaling by MRAS-complex mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-HSA-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-MMU-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-MMU-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-418457" name="cGMP effects"/>
            <pathway-xref db="Reactome" id="R-MMU-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-XTR-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-GGA-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-XTR-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-MMU-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SCE-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-DME-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9614657" name="FOXO-mediated transcription of cell death genes"/>
            <pathway-xref db="Reactome" id="R-CEL-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-DME-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-SPO-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-DDI-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-9024909" name="BDNF activates NTRK2 (TRKB) signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-MMU-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-69200" name="Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-DDI-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DME-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-975138" name="TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"/>
            <pathway-xref db="Reactome" id="R-BTA-8854521" name="Interaction between PHLDA1 and AURKA"/>
            <pathway-xref db="Reactome" id="R-GGA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8849472" name="PTK6 Down-Regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-418889" name="Caspase activation via Dependence Receptors in the absence of ligand"/>
            <pathway-xref db="Reactome" id="R-DME-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-381340" name="Transcriptional regulation of white adipocyte differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-RNO-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-HSA-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-MMU-111932" name="CaMK IV-mediated phosphorylation of CREB"/>
            <pathway-xref db="Reactome" id="R-DRE-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-DME-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-CEL-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-RNO-6804115" name="TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"/>
            <pathway-xref db="Reactome" id="R-CEL-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-RNO-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-MMU-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-BTA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-MMU-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-SSC-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-163560" name="Triglyceride catabolism"/>
            <pathway-xref db="Reactome" id="R-DME-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-DDI-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-SSC-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-112409" name="RAF-independent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DME-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-SSC-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-HSA-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-SPO-429947" name="Deadenylation of mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-9013423" name="RAC3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-9694676" name="Translation of Replicase and Assembly of the Replication Transcription Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-167200" name="Formation of HIV-1 elongation complex containing HIV-1 Tat"/>
            <pathway-xref db="Reactome" id="R-SSC-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-SCE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-HSA-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-RNO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-SPO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-DRE-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665249" name="Resistance of ERBB2 KD mutants to afatinib"/>
            <pathway-xref db="Reactome" id="R-RNO-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DME-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-DME-209228" name="Formation of the activated STAT92E dimer and transport to the nucleus"/>
            <pathway-xref db="Reactome" id="R-RNO-139910" name="Activation of BMF and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-DME-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-HSA-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-SCE-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-BTA-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-MMU-8983711" name="OAS antiviral response"/>
            <pathway-xref db="Reactome" id="R-DRE-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-DME-111932" name="CaMK IV-mediated phosphorylation of CREB"/>
            <pathway-xref db="Reactome" id="R-DRE-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-RNO-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-432553" name="Phosphorylation of PER and TIM"/>
            <pathway-xref db="Reactome" id="R-MMU-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SCE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-DDI-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9010642" name="ROBO receptors bind AKAP5"/>
            <pathway-xref db="Reactome" id="R-RNO-936837" name="Ion transport by P-type ATPases"/>
            <pathway-xref db="Reactome" id="R-MMU-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-DRE-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DME-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="Reactome" id="R-DME-214862" name="Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-GGA-351451" name="Homologous recombination repair of replication-dependent double-strand breaks"/>
            <pathway-xref db="Reactome" id="R-BTA-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-DDI-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-GGA-351433" name="ATM mediated phosphorylation of repair proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-DDI-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9661069" name="Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)"/>
            <pathway-xref db="Reactome" id="R-SCE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-RNO-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-DDI-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-DME-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-DDI-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-5602636" name="IKBKB deficiency causes SCID"/>
            <pathway-xref db="Reactome" id="R-DDI-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-RNO-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-GGA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5602498" name="MyD88 deficiency (TLR2/4)"/>
            <pathway-xref db="Reactome" id="R-MMU-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-HSA-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-6802946" name="Signaling by moderate kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-PFA-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-HSA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-211733" name="Regulation of activated PAK-2p34 by proteasome mediated degradation"/>
            <pathway-xref db="Reactome" id="R-MMU-201681" name="TCF dependent signaling in response to WNT"/>
            <pathway-xref db="Reactome" id="R-RNO-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-HSA-1839130" name="Signaling by activated point mutants of FGFR3"/>
            <pathway-xref db="Reactome" id="R-HSA-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-DME-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-SCE-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-BTA-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-HSA-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="Reactome" id="R-SSC-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-SCE-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-5654689" name="PI-3K cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-DDI-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-DME-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DDI-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-SSC-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DME-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-75893" name="TNF signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-75893" name="TNF signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-8866910" name="TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"/>
            <pathway-xref db="Reactome" id="R-HSA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-167021" name="PLC-gamma1 signalling"/>
            <pathway-xref db="Reactome" id="R-DME-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-DME-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-RNO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-CFA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-RNO-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-HSA-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209447" name="Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY"/>
            <pathway-xref db="Reactome" id="R-SPO-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CEL-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-HSA-9652282" name="Drug-mediated inhibition of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9022699" name="MECP2 regulates neuronal receptors and channels"/>
            <pathway-xref db="Reactome" id="R-CEL-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SPO-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-XTR-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SPO-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676594" name="TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-BTA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-BTA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-HSA-9027277" name="Erythropoietin activates Phospholipase C gamma (PLCG)"/>
            <pathway-xref db="Reactome" id="R-PFA-180024" name="DARPP-32 events"/>
            <pathway-xref db="Reactome" id="R-SPO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DME-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-DDI-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-MMU-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-DME-209190" name="Phosphorylation of CI"/>
            <pathway-xref db="Reactome" id="R-RNO-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-DME-209425" name="Transcriptional activtion by AP-1 transcription factor"/>
            <pathway-xref db="Reactome" id="R-MMU-442742" name="CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5210891" name="Uptake and function of anthrax toxins"/>
            <pathway-xref db="Reactome" id="R-DDI-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DME-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-CFA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DME-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2151209" name="Activation of PPARGC1A (PGC-1alpha) by phosphorylation"/>
            <pathway-xref db="Reactome" id="R-HSA-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SPO-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-GGA-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-GGA-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-DRE-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-HSA-167152" name="Formation of HIV elongation complex in the absence of HIV Tat"/>
            <pathway-xref db="Reactome" id="R-RNO-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-RNO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="MetaCyc" id="PWY-6682" name="dehydrophos biosynthesis"/>
            <pathway-xref db="Reactome" id="R-MMU-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SPO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DRE-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8854521" name="Interaction between PHLDA1 and AURKA"/>
            <pathway-xref db="Reactome" id="R-SSC-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SSC-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-SCE-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-HSA-6804759" name="Regulation of TP53 Activity through Association with Co-factors"/>
            <pathway-xref db="Reactome" id="R-MMU-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-SCE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-DDI-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DRE-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-165181" name="Inhibition of TSC complex formation by PKB"/>
            <pathway-xref db="Reactome" id="R-SCE-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-BTA-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-372708" name="p130Cas linkage to MAPK signaling for integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-RNO-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-9613354" name="Lipophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-GGA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-68881" name="Mitotic Metaphase/Anaphase Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-70221" name="Glycogen breakdown (glycogenolysis)"/>
            <pathway-xref db="Reactome" id="R-HSA-1251932" name="PLCG1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-199920" name="CREB phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DDI-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-MMU-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-SCE-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-69205" name="G1/S-Specific Transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-MMU-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-211728" name="Regulation of PAK-2p34 activity by PS-GAP/RHG10"/>
            <pathway-xref db="Reactome" id="R-HSA-9674396" name="Imatinib-resistant PDGFR mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-74751" name="Insulin receptor signalling cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-209560" name="NF-kB is activated and signals survival"/>
            <pathway-xref db="Reactome" id="R-DDI-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-GGA-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DDI-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-CEL-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-BTA-6804114" name="TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-DDI-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-DRE-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-69200" name="Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-MMU-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-73762" name="RNA Polymerase I Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-HSA-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-CEL-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DME-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-CEL-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-HSA-187706" name="Signalling to p38 via RIT and RIN"/>
            <pathway-xref db="Reactome" id="R-RNO-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-5578768" name="Physiological factors"/>
            <pathway-xref db="Reactome" id="R-DME-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-DDI-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-DRE-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DDI-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-DDI-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-9660821" name="ADORA2B mediated anti-inflammatory cytokines production"/>
            <pathway-xref db="Reactome" id="R-DRE-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-MMU-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-SCE-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-CEL-202670" name="ERKs are inactivated"/>
            <pathway-xref db="Reactome" id="R-SPO-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-DME-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-MMU-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-DME-76005" name="Response to elevated platelet cytosolic Ca2+"/>
            <pathway-xref db="Reactome" id="R-HSA-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-MMU-202427" name="Phosphorylation of CD3 and TCR zeta chains"/>
            <pathway-xref db="Reactome" id="R-DDI-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-DME-210688" name="Dephosphorylation by PTP61F phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="Reactome" id="R-MMU-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-DME-9013418" name="RHOBTB2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-SCE-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-111931" name="PKA-mediated phosphorylation of CREB"/>
            <pathway-xref db="Reactome" id="R-BTA-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-GGA-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-HSA-8935690" name="Digestion"/>
            <pathway-xref db="Reactome" id="R-SCE-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-SPO-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-CFA-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-DME-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-SPO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-76005" name="Response to elevated platelet cytosolic Ca2+"/>
            <pathway-xref db="Reactome" id="R-PFA-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DME-538898" name="Dephosphorylation of TIM"/>
            <pathway-xref db="Reactome" id="R-MMU-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-GGA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DME-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-RNO-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-HSA-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-HSA-9609690" name="HCMV Early Events"/>
            <pathway-xref db="Reactome" id="R-HSA-6802952" name="Signaling by BRAF and RAF fusions"/>
            <pathway-xref db="Reactome" id="R-MMU-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-RNO-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-BTA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-MMU-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-HSA-9696270" name="RND2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-MMU-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SPO-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-CEL-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-CEL-444257" name="RSK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-HSA-5603027" name="IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)"/>
            <pathway-xref db="Reactome" id="R-MMU-5654710" name="PI-3K cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-SPO-6804115" name="TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"/>
            <pathway-xref db="Reactome" id="R-CEL-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-SPO-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-BTA-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-SSC-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-3371378" name="Regulation by c-FLIP"/>
            <pathway-xref db="Reactome" id="R-RNO-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-DME-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-BTA-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-SCE-198765" name="Signalling to ERK5"/>
            <pathway-xref db="Reactome" id="R-HSA-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-HSA-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-MMU-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-SPO-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-HSA-428542" name="Regulation of commissural axon pathfinding by SLIT and ROBO"/>
            <pathway-xref db="Reactome" id="R-HSA-5638303" name="Inhibition of Signaling by Overexpressed EGFR"/>
            <pathway-xref db="Reactome" id="R-GGA-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-MMU-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-DRE-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-446353" name="Cell-extracellular matrix interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-1839120" name="Signaling by FGFR1 amplification mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-SCE-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-CEL-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-DME-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DDI-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-9645135" name="STAT5 Activation"/>
            <pathway-xref db="Reactome" id="R-GGA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-DRE-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-8934593" name="Regulation of RUNX1 Expression and Activity"/>
            <pathway-xref db="Reactome" id="R-SCE-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-SPO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-RNO-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-5467340" name="AXIN missense mutants destabilize the destruction complex"/>
            <pathway-xref db="Reactome" id="R-GGA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6794361" name="Neurexins and neuroligins"/>
            <pathway-xref db="Reactome" id="R-HSA-167238" name="Pausing and recovery of Tat-mediated HIV elongation"/>
            <pathway-xref db="Reactome" id="R-SSC-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-3301854" name="Nuclear Pore Complex (NPC) Disassembly"/>
            <pathway-xref db="Reactome" id="R-DDI-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-8983432" name="Interleukin-15 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-CEL-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-9013507" name="NOTCH3 Activation and Transmission of Signal to the Nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-DRE-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-RNO-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-MMU-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="MetaCyc" id="PWY-8051" name="anandamide biosynthesis I"/>
            <pathway-xref db="Reactome" id="R-HSA-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-75892" name="Platelet Adhesion to exposed collagen"/>
            <pathway-xref db="Reactome" id="R-DRE-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9620244" name="Long-term potentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-MMU-112409" name="RAF-independent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DRE-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-400253" name="Circadian Clock"/>
            <pathway-xref db="Reactome" id="R-SCE-6804758" name="Regulation of TP53 Activity through Acetylation"/>
            <pathway-xref db="Reactome" id="R-BTA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-SCE-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-SPO-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-SPO-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-DME-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-RNO-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-8875360" name="InlB-mediated entry of Listeria monocytogenes into host cell"/>
            <pathway-xref db="Reactome" id="R-DME-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8940973" name="RUNX2 regulates osteoblast differentiation"/>
            <pathway-xref db="Reactome" id="R-MMU-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-167044" name="Signalling to RAS"/>
            <pathway-xref db="Reactome" id="R-HSA-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-GGA-434001" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9013409" name="RHOJ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-MMU-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-MMU-6807004" name="Negative regulation of MET activity"/>
            <pathway-xref db="Reactome" id="R-HSA-9603505" name="NTRK3 as a dependence receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-SPO-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-RNO-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-DRE-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-MMU-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-DRE-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DME-176417" name="Phosphorylation of Emi1"/>
            <pathway-xref db="Reactome" id="R-DDI-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-RNO-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-RNO-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DDI-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-68875" name="Mitotic Prophase"/>
            <pathway-xref db="Reactome" id="R-DME-9652282" name="Drug-mediated inhibition of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665348" name="Signaling by ERBB2 ECD mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-DME-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013408" name="RHOG GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-6811555" name="PI5P Regulates TP53 Acetylation"/>
            <pathway-xref db="Reactome" id="R-HSA-4086400" name="PCP/CE pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9705462" name="Inactivation of CSF3 (G-CSF) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665246" name="Resistance of ERBB2 KD mutants to neratinib"/>
            <pathway-xref db="Reactome" id="R-MMU-936964" name="Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"/>
            <pathway-xref db="Reactome" id="R-DRE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-DDI-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-112409" name="RAF-independent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-DME-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-RNO-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-6781827" name="Transcription-Coupled Nucleotide Excision Repair (TC-NER)"/>
            <pathway-xref db="Reactome" id="R-SSC-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-DME-209409" name="Formation of the nuclear AP-1 transcription factor 'scaffolding complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-9665250" name="Resistance of ERBB2 KD mutants to AEE788"/>
            <pathway-xref db="Reactome" id="R-DME-416572" name="Sema4D induced cell migration and growth-cone collapse"/>
            <pathway-xref db="Reactome" id="R-SCE-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DDI-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-CEL-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-202670" name="ERKs are inactivated"/>
            <pathway-xref db="Reactome" id="R-SPO-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-DME-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-HSA-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-MMU-5654727" name="Negative regulation of FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="MetaCyc" id="PWY-7676" name="Kdo8N transfer to lipid IVA"/>
            <pathway-xref db="Reactome" id="R-RNO-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-MMU-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74752" name="Signaling by Insulin receptor"/>
            <pathway-xref db="Reactome" id="R-SCE-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-HSA-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-HSA-8932339" name="ROS sensing by NFE2L2"/>
            <pathway-xref db="Reactome" id="R-MMU-1483191" name="Synthesis of PC"/>
            <pathway-xref db="Reactome" id="R-CEL-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-HSA-8964315" name="G beta:gamma signalling through BTK"/>
            <pathway-xref db="Reactome" id="R-HSA-5610783" name="Degradation of GLI2 by the proteasome"/>
            <pathway-xref db="Reactome" id="R-DME-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-SCE-6804757" name="Regulation of TP53 Degradation"/>
            <pathway-xref db="Reactome" id="R-DME-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-SCE-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-DDI-68911" name="G2 Phase"/>
            <pathway-xref db="Reactome" id="R-CEL-8849474" name="PTK6 Activates STAT3"/>
            <pathway-xref db="Reactome" id="R-CEL-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-MMU-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5358752" name="T41 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-DDI-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-CEL-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-CEL-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-SSC-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="MetaCyc" id="PWY-6369" name="inositol diphosphates biosynthesis"/>
            <pathway-xref db="Reactome" id="R-RNO-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-MMU-198765" name="Signalling to ERK5"/>
            <pathway-xref db="Reactome" id="R-SPO-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-DRE-5654687" name="Downstream signaling of activated FGFR1"/>
            <pathway-xref db="MetaCyc" id="PWY-7675" name="Kdo transfer to lipid IVA (Haemophilus)"/>
            <pathway-xref db="Reactome" id="R-MMU-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-DME-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="MetaCyc" id="PWY-7905" name="Escherichia coli serotype O:9a O antigen biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-HSA-167160" name="RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"/>
            <pathway-xref db="Reactome" id="R-MMU-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-SCE-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-CEL-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-GGA-437986" name="Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-5654712" name="FRS-mediated FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-MMU-416550" name="Sema4D mediated inhibition of cell attachment and migration"/>
            <pathway-xref db="Reactome" id="R-RNO-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-1483191" name="Synthesis of PC"/>
            <pathway-xref db="MetaCyc" id="PWY-7511" name="protein ubiquitination"/>
            <pathway-xref db="Reactome" id="R-HSA-9702600" name="midostaurin-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-SPO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DME-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-DME-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9652282" name="Drug-mediated inhibition of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-390089" name="Formation of the Hippo kinase cassette"/>
            <pathway-xref db="Reactome" id="R-HSA-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DME-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-8878166" name="Transcriptional regulation by RUNX2"/>
            <pathway-xref db="Reactome" id="R-SPO-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-428890" name="Role of ABL in ROBO-SLIT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-DRE-5654695" name="PI-3K cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-HSA-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-PFA-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-DME-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-MMU-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-2219530" name="Constitutive Signaling by Aberrant PI3K in Cancer"/>
            <pathway-xref db="Reactome" id="R-SSC-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-SPO-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-DME-4420097" name="VEGFA-VEGFR2 Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-111446" name="Activation of BIM and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-SSC-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-MMU-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9022535" name="Loss of phosphorylation of MECP2 at T308"/>
            <pathway-xref db="Reactome" id="R-HSA-9632697" name="Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4"/>
            <pathway-xref db="Reactome" id="R-HSA-1170546" name="Prolactin receptor signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-CEL-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-DME-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-982772" name="Growth hormone receptor signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-DME-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-DME-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="Reactome" id="R-BTA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-446388" name="Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"/>
            <pathway-xref db="Reactome" id="R-DME-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-3249367" name="STAT6-mediated induction of chemokines"/>
            <pathway-xref db="Reactome" id="R-RNO-8875656" name="MET receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-399719" name="Trafficking of AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-DME-432524" name="Degradation of PER"/>
            <pathway-xref db="Reactome" id="R-SSC-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-CEL-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-DRE-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-RNO-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CEL-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-CEL-8849468" name="PTK6 Regulates Proteins Involved in RNA Processing"/>
            <pathway-xref db="Reactome" id="R-CEL-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-DME-69478" name="G2/M DNA replication checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-381038" name="XBP1(S) activates chaperone genes"/>
            <pathway-xref db="Reactome" id="R-DDI-202670" name="ERKs are inactivated"/>
            <pathway-xref db="Reactome" id="R-MMU-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-SSC-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-DME-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-MMU-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-SCE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-SCE-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SCE-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-DME-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-SSC-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-CEL-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-CEL-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8878166" name="Transcriptional regulation by RUNX2"/>
            <pathway-xref db="Reactome" id="R-HSA-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-199920" name="CREB phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-9007892" name="Interleukin-38 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5685938" name="HDR through Single Strand Annealing (SSA)"/>
            <pathway-xref db="Reactome" id="R-SCE-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-MMU-2562578" name="TRIF-mediated programmed cell death"/>
            <pathway-xref db="Reactome" id="R-SPO-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8851805" name="MET activates RAS signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-SCE-1489509" name="DAG and IP3 signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9634638" name="Estrogen-dependent nuclear events downstream of ESR-membrane signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-CEL-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-SCE-6804115" name="TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"/>
            <pathway-xref db="Reactome" id="R-RNO-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-MMU-6783783" name="Interleukin-10 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654228" name="Phospholipase C-mediated cascade, FGFR4"/>
            <pathway-xref db="Reactome" id="R-HSA-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-442729" name="CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"/>
            <pathway-xref db="Reactome" id="R-DRE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-RNO-5357956" name="TNFR1-induced NFkappaB signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-SPO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-209338" name="Assembly of the 'signalling complexes'"/>
            <pathway-xref db="Reactome" id="R-HSA-167172" name="Transcription of the HIV genome"/>
            <pathway-xref db="Reactome" id="R-SCE-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-MMU-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-GGA-1227892" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-BTA-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-DME-1963642" name="PI3K events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-DME-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-SPO-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-HSA-167590" name="Nef Mediated CD4 Down-regulation"/>
            <pathway-xref db="Reactome" id="R-RNO-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-CEL-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-DRE-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-CEL-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SCE-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-68962" name="Activation of the pre-replicative complex"/>
            <pathway-xref db="Reactome" id="R-SPO-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-8875791" name="MET activates STAT3"/>
            <pathway-xref db="Reactome" id="R-RNO-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-MMU-5654221" name="Phospholipase C-mediated cascade, FGFR2"/>
            <pathway-xref db="Reactome" id="R-MMU-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-BTA-8849470" name="PTK6 Regulates Cell Cycle"/>
            <pathway-xref db="Reactome" id="R-DDI-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-6804116" name="TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-HSA-3656535" name="TGFBR1 LBD Mutants in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-HSA-8865999" name="MET activates PTPN11"/>
            <pathway-xref db="Reactome" id="R-PFA-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-HSA-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-CEL-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-MMU-70221" name="Glycogen breakdown (glycogenolysis)"/>
            <pathway-xref db="Reactome" id="R-HSA-179409" name="APC-Cdc20 mediated degradation of Nek2A"/>
            <pathway-xref db="Reactome" id="R-RNO-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-DME-114516" name="Disinhibition of SNARE formation"/>
            <pathway-xref db="Reactome" id="R-MMU-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-CEL-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-HSA-3134975" name="Regulation of innate immune responses to cytosolic DNA"/>
            <pathway-xref db="Reactome" id="R-DME-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-CEL-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-DME-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-DRE-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-68911" name="G2 Phase"/>
            <pathway-xref db="Reactome" id="R-HSA-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-HSA-975871" name="MyD88 cascade initiated on plasma membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DRE-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-RNO-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-HSA-3656532" name="TGFBR1 KD Mutants in Cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-8985947" name="Interleukin-9 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-CEL-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-RNO-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DDI-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-MMU-1963640" name="GRB2 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9703648" name="Signaling by FLT3 ITD and TKD mutants"/>
            <pathway-xref db="Reactome" id="R-SPO-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-SCE-1660516" name="Synthesis of PIPs at the early endosome membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-GGA-265976" name="Homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-RNO-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-GGA-1502540" name="Signaling by Activin"/>
            <pathway-xref db="Reactome" id="R-RNO-416482" name="G alpha (12/13) signalling events"/>
            <pathway-xref db="Reactome" id="R-MMU-5654693" name="FRS-mediated FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209214" name="Phosphorylation of SMO"/>
            <pathway-xref db="Reactome" id="R-HSA-8986944" name="Transcriptional Regulation by MECP2"/>
            <pathway-xref db="Reactome" id="R-DDI-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-3000170" name="Syndecan interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-9630794" name="Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6"/>
            <pathway-xref db="Reactome" id="R-MMU-5218900" name="CASP8 activity is inhibited"/>
            <pathway-xref db="Reactome" id="R-CFA-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-HSA-8878166" name="Transcriptional regulation by RUNX2"/>
            <pathway-xref db="Reactome" id="R-DRE-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-RNO-2029485" name="Role of phospholipids in phagocytosis"/>
            <pathway-xref db="Reactome" id="R-MMU-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-HSA-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-418597" name="G alpha (z) signalling events"/>
            <pathway-xref db="Reactome" id="R-DRE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-5610785" name="GLI3 is processed to GLI3R by the proteasome"/>
            <pathway-xref db="Reactome" id="R-HSA-2644606" name="Constitutive Signaling by NOTCH1 PEST Domain Mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-442729" name="CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"/>
            <pathway-xref db="Reactome" id="R-HSA-9028731" name="Activated NTRK2 signals through FRS2 and FRS3"/>
            <pathway-xref db="Reactome" id="R-SCE-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-MMU-5654700" name="FRS-mediated FGFR2 signaling"/>
            <pathway-xref db="Reactome" id="R-CFA-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-5625740" name="RHO GTPases activate PKNs"/>
            <pathway-xref db="Reactome" id="R-MMU-3270619" name="IRF3-mediated induction of type I IFN"/>
            <pathway-xref db="Reactome" id="R-MMU-8849472" name="PTK6 Down-Regulation"/>
            <pathway-xref db="Reactome" id="R-SPO-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-RNO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-SPO-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-3928662" name="EPHB-mediated forward signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665737" name="Drug resistance in ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-75815" name="Ubiquitin-dependent degradation of Cyclin D"/>
            <pathway-xref db="Reactome" id="R-DRE-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9013106" name="RHOC GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5218900" name="CASP8 activity is inhibited"/>
            <pathway-xref db="Reactome" id="R-CEL-8856828" name="Clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DRE-9020558" name="Interleukin-2 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-HSA-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-209396" name="Phosphorylation of ARM"/>
            <pathway-xref db="Reactome" id="R-HSA-9702577" name="semaxanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DME-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-166208" name="mTORC1-mediated signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-202670" name="ERKs are inactivated"/>
            <pathway-xref db="Reactome" id="R-RNO-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-909733" name="Interferon alpha/beta signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-HSA-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-6804114" name="TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-MMU-432040" name="Vasopressin regulates renal water homeostasis via Aquaporins"/>
            <pathway-xref db="Reactome" id="R-RNO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-RNO-9607240" name="FLT3 Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-5663213" name="RHO GTPases Activate WASPs and WAVEs"/>
            <pathway-xref db="Reactome" id="R-HSA-8939243" name="RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"/>
            <pathway-xref db="Reactome" id="R-CFA-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-XTR-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-HSA-9669924" name="Masitinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-DRE-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="MetaCyc" id="PWY-7975" name="adenosylcobalamin biosynthesis from adenosylcobinamide-GDP II"/>
            <pathway-xref db="Reactome" id="R-CEL-114516" name="Disinhibition of SNARE formation"/>
            <pathway-xref db="Reactome" id="R-MMU-5357905" name="Regulation of TNFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-9013422" name="RHOBTB1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-GGA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-5625900" name="RHO GTPases activate CIT"/>
            <pathway-xref db="Reactome" id="R-RNO-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-179812" name="GRB2 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-6811555" name="PI5P Regulates TP53 Acetylation"/>
            <pathway-xref db="Reactome" id="R-DME-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-RNO-9026527" name="Activated NTRK2 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-69416" name="Dimerization of procaspase-8"/>
            <pathway-xref db="Reactome" id="R-GGA-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-GGA-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SCE-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-RNO-5693607" name="Processing of DNA double-strand break ends"/>
            <pathway-xref db="Reactome" id="R-CEL-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DRE-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-201451" name="Signaling by BMP"/>
            <pathway-xref db="Reactome" id="R-MMU-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9020958" name="Interleukin-21 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DDI-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-DME-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-PFA-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-HSA-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-180024" name="DARPP-32 events"/>
            <pathway-xref db="Reactome" id="R-CEL-1483191" name="Synthesis of PC"/>
            <pathway-xref db="Reactome" id="R-SCE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-8935690" name="Digestion"/>
            <pathway-xref db="Reactome" id="R-MMU-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-RNO-111995" name="phospho-PLA2 pathway"/>
            <pathway-xref db="Reactome" id="R-DDI-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-CEL-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-SSC-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9665686" name="Signaling by ERBB2 TMD/JMD mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-5625886" name="Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"/>
            <pathway-xref db="Reactome" id="R-GGA-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-RNO-9634635" name="Estrogen-stimulated signaling through PRKCZ"/>
            <pathway-xref db="Reactome" id="R-CEL-8878166" name="Transcriptional regulation by RUNX2"/>
            <pathway-xref db="Reactome" id="R-HSA-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-HSA-9662834" name="CD163 mediating an anti-inflammatory response"/>
            <pathway-xref db="Reactome" id="R-RNO-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-69478" name="G2/M DNA replication checkpoint"/>
            <pathway-xref db="Reactome" id="R-DDI-5674135" name="MAP2K and MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-MMU-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-HSA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DME-451806" name="Phosphorylation-independent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-HSA-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-BTA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-1250342" name="PI3K events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-SPO-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-MMU-6804116" name="TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-DME-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-DRE-2559580" name="Oxidative Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-HSA-1839128" name="FGFR4 mutant receptor activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9652282" name="Drug-mediated inhibition of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-186763" name="Downstream signal transduction"/>
            <pathway-xref db="Reactome" id="R-HSA-9683610" name="Maturation of nucleoprotein"/>
            <pathway-xref db="Reactome" id="R-DRE-936837" name="Ion transport by P-type ATPases"/>
            <pathway-xref db="Reactome" id="R-RNO-5654726" name="Negative regulation of FGFR1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-SCE-5668541" name="TNFR2 non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-1059683" name="Interleukin-6 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-MMU-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SPO-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-HSA-418555" name="G alpha (s) signalling events"/>
            <pathway-xref db="Reactome" id="R-SSC-8854521" name="Interaction between PHLDA1 and AURKA"/>
            <pathway-xref db="Reactome" id="R-DRE-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-HSA-9702605" name="pexidartinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DME-209155" name="Phosphorylation of AXN and APC"/>
            <pathway-xref db="Reactome" id="R-RNO-877300" name="Interferon gamma signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-113418" name="Formation of the Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-RNO-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-RNO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-DME-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-DME-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-MMU-2029482" name="Regulation of actin dynamics for phagocytic cup formation"/>
            <pathway-xref db="Reactome" id="R-HSA-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-9635465" name="Suppression of apoptosis"/>
            <pathway-xref db="Reactome" id="R-RNO-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-MMU-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-DME-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-DRE-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-DME-1474151" name="Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"/>
            <pathway-xref db="Reactome" id="R-SPO-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-BTA-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9656223" name="Signaling by RAF1 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-5655291" name="Signaling by FGFR4 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-SCE-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-SPO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DME-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-CEL-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-MMU-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5607761" name="Dectin-1 mediated noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-RNO-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-RNO-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-HSA-6802955" name="Paradoxical activation of RAF signaling by kinase inactive BRAF"/>
            <pathway-xref db="Reactome" id="R-DDI-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-MMU-9674555" name="Signaling by CSF3 (G-CSF)"/>
            <pathway-xref db="Reactome" id="R-DRE-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-SCE-176187" name="Activation of ATR in response to replication stress"/>
            <pathway-xref db="Reactome" id="R-MMU-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-DDI-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-DME-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-DRE-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-MMU-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-418457" name="cGMP effects"/>
            <pathway-xref db="Reactome" id="R-HSA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SPO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-RNO-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-MMU-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-DRE-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9020933" name="Interleukin-23 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-MMU-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-DDI-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-HSA-1445148" name="Translocation of SLC2A4 (GLUT4) to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-2404192" name="Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)"/>
            <pathway-xref db="Reactome" id="R-DME-77387" name="Insulin receptor recycling"/>
            <pathway-xref db="Reactome" id="R-RNO-1236394" name="Signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-SCE-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-210993" name="Tie2 Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-111447" name="Activation of BAD and translocation to mitochondria"/>
            <pathway-xref db="Reactome" id="R-DRE-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669933" name="Signaling by kinase domain mutants of KIT"/>
            <pathway-xref db="Reactome" id="R-RNO-4615885" name="SUMOylation of DNA replication proteins"/>
            <pathway-xref db="Reactome" id="R-HSA-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-9645460" name="Alpha-protein kinase 1 signaling pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9702518" name="STAT5 activation downstream of FLT3 ITD mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-4755510" name="SUMOylation of immune response proteins"/>
            <pathway-xref db="Reactome" id="R-SPO-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-DME-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8876198" name="RAB GEFs exchange GTP for GDP on RABs"/>
            <pathway-xref db="Reactome" id="R-MMU-8849474" name="PTK6 Activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-176412" name="Phosphorylation of the APC/C"/>
            <pathway-xref db="Reactome" id="R-RNO-975138" name="TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"/>
            <pathway-xref db="Reactome" id="R-SSC-8854518" name="AURKA Activation by TPX2"/>
            <pathway-xref db="Reactome" id="R-RNO-6806942" name="MET Receptor Activation"/>
            <pathway-xref db="Reactome" id="R-HSA-5676594" name="TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-MMU-380270" name="Recruitment of mitotic centrosome proteins and complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-9670439" name="Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-SSC-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-CEL-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-DDI-442720" name="CREB1 phosphorylation through the activation of Adenylate Cyclase"/>
            <pathway-xref db="Reactome" id="R-HSA-9013973" name="TICAM1-dependent activation of IRF3/IRF7"/>
            <pathway-xref db="Reactome" id="R-SCE-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-RNO-8964616" name="G beta:gamma signalling through CDC42"/>
            <pathway-xref db="Reactome" id="R-MMU-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-SCE-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-HSA-8862803" name="Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"/>
            <pathway-xref db="Reactome" id="R-MMU-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-MMU-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-MMU-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-HSA-9634600" name="Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"/>
            <pathway-xref db="Reactome" id="R-CEL-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-937042" name="IRAK2 mediated activation of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-CEL-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-MMU-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-HSA-9706377" name="FLT3 signaling by CBL mutants"/>
            <pathway-xref db="Reactome" id="R-SCE-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-RNO-69200" name="Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes"/>
            <pathway-xref db="Reactome" id="R-MMU-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-432142" name="Platelet sensitization by LDL"/>
            <pathway-xref db="Reactome" id="R-MMU-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-DME-212718" name="EGFR interacts with phospholipase C-gamma"/>
            <pathway-xref db="Reactome" id="R-SPO-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-RNO-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-DME-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-HSA-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-CEL-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-MMU-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-CEL-75955" name="RNA Polymerase II Transcription Elongation"/>
            <pathway-xref db="Reactome" id="R-HSA-9702636" name="tandutinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DME-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-MMU-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-5654688" name="SHC-mediated cascade:FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-8875513" name="MET interacts with TNS proteins"/>
            <pathway-xref db="Reactome" id="R-CEL-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SPO-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-MMU-9614399" name="Regulation of localization of FOXO transcription factors"/>
            <pathway-xref db="Reactome" id="R-DRE-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-HSA-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-RNO-190322" name="FGFR4 ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-214844" name="DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-5690714" name="CD22 mediated BCR regulation"/>
            <pathway-xref db="Reactome" id="R-CEL-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-CEL-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-GGA-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-RNO-216083" name="Integrin cell surface interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-RNO-70221" name="Glycogen breakdown (glycogenolysis)"/>
            <pathway-xref db="Reactome" id="R-HSA-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-SPO-442729" name="CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"/>
            <pathway-xref db="Reactome" id="R-SPO-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-167246" name="Tat-mediated elongation of the HIV-1 transcript"/>
            <pathway-xref db="Reactome" id="R-CEL-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-MMU-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-GGA-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-RNO-204005" name="COPII-mediated vesicle transport"/>
            <pathway-xref db="Reactome" id="R-MMU-112411" name="MAPK1 (ERK2) activation"/>
            <pathway-xref db="Reactome" id="R-RNO-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-HSA-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-RNO-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-9034013" name="NTF3 activates NTRK3 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-MMU-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-DME-456926" name="Thrombin signalling through proteinase activated receptors (PARs)"/>
            <pathway-xref db="Reactome" id="R-MMU-9696264" name="RND3 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-111995" name="phospho-PLA2 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9013695" name="NOTCH4 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="Reactome" id="R-HSA-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DRE-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-74749" name="Signal attenuation"/>
            <pathway-xref db="Reactome" id="R-RNO-112382" name="Formation of RNA Pol II elongation complex"/>
            <pathway-xref db="Reactome" id="R-HSA-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-73772" name="RNA Polymerase I Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-GGA-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-168927" name="TICAM1, RIP1-mediated IKK complex recruitment"/>
            <pathway-xref db="Reactome" id="R-HSA-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-RNO-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-MMU-8852405" name="Signaling by MST1"/>
            <pathway-xref db="Reactome" id="R-MMU-5654719" name="SHC-mediated cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-CEL-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-HSA-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-RNO-2980767" name="Activation of NIMA Kinases NEK9, NEK6, NEK7"/>
            <pathway-xref db="Reactome" id="R-MMU-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-SSC-6804114" name="TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-HSA-9630791" name="Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4"/>
            <pathway-xref db="Reactome" id="R-RNO-202424" name="Downstream TCR signaling"/>
            <pathway-xref db="Reactome" id="R-DME-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-RNO-442742" name="CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-380284" name="Loss of proteins required for interphase microtubule organization from the centrosome"/>
            <pathway-xref db="Reactome" id="R-DDI-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-GGA-451478" name="ERK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-DRE-1251985" name="Nuclear signaling by ERBB4"/>
            <pathway-xref db="Reactome" id="R-HSA-9673768" name="Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"/>
            <pathway-xref db="Reactome" id="R-RNO-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-MMU-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-CEL-8934593" name="Regulation of RUNX1 Expression and Activity"/>
            <pathway-xref db="Reactome" id="R-GGA-2730905" name="Role of LAT2/NTAL/LAB on calcium mobilization"/>
            <pathway-xref db="Reactome" id="R-DME-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-MMU-68875" name="Mitotic Prophase"/>
            <pathway-xref db="Reactome" id="R-DRE-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-HSA-5173105" name="O-linked glycosylation"/>
            <pathway-xref db="Reactome" id="R-CEL-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-8984722" name="Interleukin-35 Signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-HSA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-CEL-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-RNO-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-HSA-1810476" name="RIP-mediated NFkB activation via ZBP1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-DRE-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-MMU-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-MMU-5635838" name="Activation of SMO"/>
            <pathway-xref db="Reactome" id="R-MMU-1660499" name="Synthesis of PIPs at the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DRE-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="Reactome" id="R-DDI-69231" name="Cyclin D associated events in G1"/>
            <pathway-xref db="Reactome" id="R-HSA-5603029" name="IkBA variant leads to EDA-ID"/>
            <pathway-xref db="Reactome" id="R-SSC-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-8942233" name="Intestinal infectious diseases"/>
            <pathway-xref db="Reactome" id="R-DME-198753" name="ERK/MAPK targets"/>
            <pathway-xref db="Reactome" id="R-CEL-5205685" name="PINK1-PRKN Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-RNO-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-SPO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DME-8941858" name="Regulation of RUNX3 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-MMU-936837" name="Ion transport by P-type ATPases"/>
            <pathway-xref db="Reactome" id="R-MMU-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SPO-114516" name="Disinhibition of SNARE formation"/>
            <pathway-xref db="Reactome" id="R-MMU-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-MMU-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DME-209413" name="Assembly of the 'destruction complex'"/>
            <pathway-xref db="Reactome" id="R-HSA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-DRE-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-BTA-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-DME-2871809" name="FCERI mediated Ca+2 mobilization"/>
            <pathway-xref db="Reactome" id="R-HSA-5603037" name="IRAK4 deficiency (TLR5)"/>
            <pathway-xref db="Reactome" id="R-HSA-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1266695" name="Interleukin-7 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-74713" name="IRS activation"/>
            <pathway-xref db="Reactome" id="R-SSC-936837" name="Ion transport by P-type ATPases"/>
            <pathway-xref db="Reactome" id="R-CEL-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-DRE-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-9027284" name="Erythropoietin activates RAS"/>
            <pathway-xref db="Reactome" id="R-RNO-72086" name="mRNA Capping"/>
            <pathway-xref db="Reactome" id="R-SPO-68884" name="Mitotic Telophase/Cytokinesis"/>
            <pathway-xref db="Reactome" id="R-SCE-141430" name="Inactivation of APC/C via direct inhibition of the APC/C complex"/>
            <pathway-xref db="Reactome" id="R-RNO-445355" name="Smooth Muscle Contraction"/>
            <pathway-xref db="Reactome" id="R-DDI-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-RNO-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-CEL-1912408" name="Pre-NOTCH Transcription and Translation"/>
            <pathway-xref db="Reactome" id="R-RNO-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-427413" name="NoRC negatively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-SPO-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-DME-9018519" name="Estrogen-dependent gene expression"/>
            <pathway-xref db="Reactome" id="R-CEL-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-DRE-933542" name="TRAF6 mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-MMU-9603381" name="Activated NTRK3 signals through PI3K"/>
            <pathway-xref db="Reactome" id="R-CEL-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DRE-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-9013424" name="RHOV GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-167287" name="HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-MMU-446343" name="Localization of the PINCH-ILK-PARVIN complex to focal adhesions"/>
            <pathway-xref db="Reactome" id="R-CEL-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-937039" name="IRAK1 recruits IKK complex"/>
            <pathway-xref db="Reactome" id="R-SSC-2980767" name="Activation of NIMA Kinases NEK9, NEK6, NEK7"/>
            <pathway-xref db="Reactome" id="R-MMU-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-MMU-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5689896" name="Ovarian tumor domain proteases"/>
            <pathway-xref db="Reactome" id="R-HSA-2033519" name="Activated point mutants of FGFR2"/>
            <pathway-xref db="Reactome" id="R-SCE-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-HSA-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-HSA-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DDI-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-202733" name="Cell surface interactions at the vascular wall"/>
            <pathway-xref db="Reactome" id="R-CEL-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-5689880" name="Ub-specific processing proteases"/>
            <pathway-xref db="Reactome" id="R-DME-211163" name="AKT-mediated inactivation of FOXO1A"/>
            <pathway-xref db="Reactome" id="R-HSA-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-CEL-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5620912" name="Anchoring of the basal body to the plasma membrane"/>
            <pathway-xref db="Reactome" id="R-DDI-198765" name="Signalling to ERK5"/>
            <pathway-xref db="Reactome" id="R-RNO-2428928" name="IRS-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9702596" name="lestaurtinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-9702569" name="KW2449-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-2559586" name="DNA Damage/Telomere Stress Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-MMU-171319" name="Telomere Extension By Telomerase"/>
            <pathway-xref db="Reactome" id="R-HSA-9703009" name="tamatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DME-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-CEL-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-RNO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DDI-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-MMU-8874081" name="MET activates PTK2 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-442742" name="CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-DME-390023" name="Subcellular localisation of D"/>
            <pathway-xref db="Reactome" id="R-MMU-389948" name="PD-1 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1502540" name="Signaling by Activin"/>
            <pathway-xref db="Reactome" id="R-DRE-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-RNO-399997" name="Acetylcholine regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-HSA-5358749" name="S37 mutants of beta-catenin aren't phosphorylated"/>
            <pathway-xref db="Reactome" id="R-DME-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-HSA-73728" name="RNA Polymerase I Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-933541" name="TRAF6 mediated IRF7 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-1839122" name="Signaling by activated point mutants of FGFR1"/>
            <pathway-xref db="Reactome" id="R-MMU-8934593" name="Regulation of RUNX1 Expression and Activity"/>
            <pathway-xref db="Reactome" id="R-DME-450604" name="KSRP (KHSRP) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-XTR-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-RNO-9616222" name="Transcriptional regulation of granulopoiesis"/>
            <pathway-xref db="Reactome" id="R-HSA-2454202" name="Fc epsilon receptor (FCERI) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5693616" name="Presynaptic phase of homologous DNA pairing and strand exchange"/>
            <pathway-xref db="Reactome" id="R-DDI-442729" name="CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"/>
            <pathway-xref db="Reactome" id="R-SPO-9013148" name="CDC42 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-209440" name="Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM"/>
            <pathway-xref db="Reactome" id="R-HSA-3304356" name="SMAD2/3 Phosphorylation Motif Mutants in Cancer"/>
            <pathway-xref db="Reactome" id="R-SCE-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-DDI-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-9686347" name="Microbial modulation of RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-HSA-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2173791" name="TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"/>
            <pathway-xref db="Reactome" id="R-DRE-5654704" name="SHC-mediated cascade:FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-MMU-5654720" name="PI-3K cascade:FGFR4"/>
            <pathway-xref db="Reactome" id="R-MMU-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-DRE-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-HSA-112409" name="RAF-independent MAPK1/3 activation"/>
            <pathway-xref db="Reactome" id="R-HSA-196299" name="Beta-catenin phosphorylation cascade"/>
            <pathway-xref db="Reactome" id="R-SCE-111932" name="CaMK IV-mediated phosphorylation of CREB"/>
            <pathway-xref db="Reactome" id="R-SPO-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9034864" name="Activated NTRK3 signals through RAS"/>
            <pathway-xref db="Reactome" id="R-CEL-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-MMU-8854050" name="FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"/>
            <pathway-xref db="Reactome" id="R-HSA-9673324" name="WNT5:FZD7-mediated leishmania damping"/>
            <pathway-xref db="Reactome" id="R-HSA-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-DME-392517" name="Rap1 signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-190375" name="FGFR2c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-HSA-9702581" name="crenolanib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DRE-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-CEL-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-HSA-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-RNO-199920" name="CREB phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DDI-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-CFA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702632" name="sunitinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-174048" name="APC/C:Cdc20 mediated degradation of Cyclin B"/>
            <pathway-xref db="Reactome" id="R-HSA-8943724" name="Regulation of PTEN gene transcription"/>
            <pathway-xref db="Reactome" id="R-HSA-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-DME-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-DME-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-CEL-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-RNO-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-HSA-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-180024" name="DARPP-32 events"/>
            <pathway-xref db="Reactome" id="R-MMU-8854691" name="Interleukin-20 family signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1362300" name="Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-202430" name="Translocation of ZAP-70 to Immunological synapse"/>
            <pathway-xref db="Reactome" id="R-RNO-186797" name="Signaling by PDGF"/>
            <pathway-xref db="Reactome" id="R-CEL-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5673001" name="RAF/MAP kinase cascade"/>
            <pathway-xref db="Reactome" id="R-DME-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-416476" name="G alpha (q) signalling events"/>
            <pathway-xref db="Reactome" id="R-DDI-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DDI-69202" name="Cyclin E associated events during G1/S transition"/>
            <pathway-xref db="MetaCyc" id="PWY-7886" name="cell-surface glycoconjugate-linked phosphocholine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-GGA-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-DME-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-HSA-167243" name="Tat-mediated HIV elongation arrest and recovery"/>
            <pathway-xref db="Reactome" id="R-MMU-5654219" name="Phospholipase C-mediated cascade: FGFR1"/>
            <pathway-xref db="Reactome" id="R-DME-512988" name="Interleukin-3, Interleukin-5 and GM-CSF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-171007" name="p38MAPK events"/>
            <pathway-xref db="Reactome" id="R-RNO-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5610787" name="Hedgehog 'off' state"/>
            <pathway-xref db="Reactome" id="R-DME-190374" name="FGFR1c and Klotho ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9669936" name="Sorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-MMU-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-SPO-9013406" name="RHOQ GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-CEL-5675221" name="Negative regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-GGA-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-CEL-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-MMU-8849468" name="PTK6 Regulates Proteins Involved in RNA Processing"/>
            <pathway-xref db="Reactome" id="R-RNO-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-DME-199418" name="Negative regulation of the PI3K/AKT network"/>
            <pathway-xref db="Reactome" id="R-HSA-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-MMU-195399" name="VEGF binds to VEGFR leading to receptor dimerization"/>
            <pathway-xref db="Reactome" id="R-CEL-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-SPO-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-8866376" name="Reelin signalling pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-6782315" name="tRNA modification in the nucleus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-212436" name="Generic Transcription Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-983695" name="Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"/>
            <pathway-xref db="Reactome" id="R-CEL-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-CEL-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-HSA-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DME-1169091" name="Activation of NF-kappaB in B cells"/>
            <pathway-xref db="Reactome" id="R-RNO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-SCE-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-MMU-1307965" name="betaKlotho-mediated ligand binding"/>
            <pathway-xref db="Reactome" id="R-DME-182971" name="EGFR downregulation"/>
            <pathway-xref db="Reactome" id="R-XTR-2565942" name="Regulation of PLK1 Activity at G2/M Transition"/>
            <pathway-xref db="Reactome" id="R-SSC-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-RNO-2428933" name="SHC-related events triggered by IGF1R"/>
            <pathway-xref db="Reactome" id="R-HSA-9020591" name="Interleukin-12 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-DME-8953750" name="Transcriptional Regulation by E2F6"/>
            <pathway-xref db="Reactome" id="R-HSA-8851907" name="MET activates PI3K/AKT signaling"/>
            <pathway-xref db="Reactome" id="R-DME-209159" name="Assembly of the CI containing complexes"/>
            <pathway-xref db="Reactome" id="R-HSA-6807505" name="RNA polymerase II transcribes snRNA genes"/>
            <pathway-xref db="Reactome" id="R-MMU-73728" name="RNA Polymerase I Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-HSA-450513" name="Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-HSA-9702614" name="ponatinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-HSA-5655302" name="Signaling by FGFR1 in disease"/>
            <pathway-xref db="Reactome" id="R-MMU-168928" name="DDX58/IFIH1-mediated induction of interferon-alpha/beta"/>
            <pathway-xref db="Reactome" id="R-DRE-376172" name="DSCAM interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-8963896" name="HDL assembly"/>
            <pathway-xref db="Reactome" id="R-HSA-176034" name="Interactions of Tat with host cellular proteins"/>
            <pathway-xref db="Reactome" id="R-DDI-69017" name="CDK-mediated phosphorylation and removal of Cdc6"/>
            <pathway-xref db="Reactome" id="R-HSA-388844" name="Receptor-type tyrosine-protein phosphatases"/>
            <pathway-xref db="Reactome" id="R-RNO-449836" name="Other interleukin signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-200425" name="Carnitine metabolism"/>
            <pathway-xref db="Reactome" id="R-HSA-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-DME-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-RNO-8854521" name="Interaction between PHLDA1 and AURKA"/>
            <pathway-xref db="Reactome" id="R-SCE-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SPO-73779" name="RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-DME-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DME-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1250347" name="SHC1 events in ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-198323" name="AKT phosphorylates targets in the cytosol"/>
            <pathway-xref db="Reactome" id="R-DDI-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-HSA-442982" name="Ras activation upon Ca2+ influx through NMDA receptor"/>
            <pathway-xref db="Reactome" id="R-MMU-8849470" name="PTK6 Regulates Cell Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-9619483" name="Activation of AMPK downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-MMU-3928665" name="EPH-ephrin mediated repulsion of cells"/>
            <pathway-xref db="Reactome" id="R-HSA-6811555" name="PI5P Regulates TP53 Acetylation"/>
            <pathway-xref db="Reactome" id="R-CEL-389357" name="CD28 dependent PI3K/Akt signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-110056" name="MAPK3 (ERK1) activation"/>
            <pathway-xref db="Reactome" id="R-GGA-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-73728" name="RNA Polymerase I Promoter Opening"/>
            <pathway-xref db="Reactome" id="R-RNO-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-MMU-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-RNO-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5673000" name="RAF activation"/>
            <pathway-xref db="Reactome" id="R-SPO-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-CEL-114508" name="Effects of PIP2 hydrolysis"/>
            <pathway-xref db="Reactome" id="R-RNO-3371571" name="HSF1-dependent transactivation"/>
            <pathway-xref db="Reactome" id="R-CEL-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-RNO-201451" name="Signaling by BMP"/>
            <pathway-xref db="Reactome" id="R-MMU-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-DRE-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-CEL-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-DME-437239" name="Recycling pathway of L1"/>
            <pathway-xref db="Reactome" id="R-RNO-69601" name="Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"/>
            <pathway-xref db="Reactome" id="R-DME-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-CEL-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DRE-174178" name="APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-975163" name="IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-9022692" name="Regulation of MECP2 expression and activity"/>
            <pathway-xref db="Reactome" id="R-CEL-6814122" name="Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"/>
            <pathway-xref db="Reactome" id="R-PFA-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-SCE-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-DRE-190373" name="FGFR1c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-MMU-2682334" name="EPH-Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-2173789" name="TGF-beta receptor signaling activates SMADs"/>
            <pathway-xref db="Reactome" id="R-RNO-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-MMU-8939211" name="ESR-mediated signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-75035" name="Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"/>
            <pathway-xref db="Reactome" id="R-CEL-8849469" name="PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1"/>
            <pathway-xref db="Reactome" id="R-RNO-156711" name="Polo-like kinase mediated events"/>
            <pathway-xref db="Reactome" id="R-RNO-210990" name="PECAM1 interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-912526" name="Interleukin receptor SHC signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DME-381042" name="PERK regulates gene expression"/>
            <pathway-xref db="Reactome" id="R-RNO-165159" name="MTOR signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-111465" name="Apoptotic cleavage of cellular proteins"/>
            <pathway-xref db="Reactome" id="R-RNO-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-9627069" name="Regulation of the apoptosome activity"/>
            <pathway-xref db="Reactome" id="R-MMU-140534" name="Caspase activation via Death Receptors in the presence of ligand"/>
            <pathway-xref db="Reactome" id="R-HSA-8939245" name="RUNX1 regulates transcription of genes involved in BCR signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-9669929" name="Regorafenib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-BTA-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DRE-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-HSA-9027283" name="Erythropoietin activates STAT5"/>
            <pathway-xref db="Reactome" id="R-DDI-68949" name="Orc1 removal from chromatin"/>
            <pathway-xref db="Reactome" id="R-DRE-399954" name="Sema3A PAK dependent Axon repulsion"/>
            <pathway-xref db="Reactome" id="R-MMU-191650" name="Regulation of gap junction activity"/>
            <pathway-xref db="Reactome" id="R-HSA-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-3642279" name="TGFBR2 MSI Frameshift Mutants in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-8852276" name="The role of GTSE1 in G2/M progression after G2 checkpoint"/>
            <pathway-xref db="Reactome" id="R-HSA-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-SCE-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-MMU-937041" name="IKK complex recruitment mediated by RIP1"/>
            <pathway-xref db="Reactome" id="R-HSA-167158" name="Formation of the HIV-1 Early Elongation Complex"/>
            <pathway-xref db="Reactome" id="R-DME-174184" name="Cdc20:Phospho-APC/C mediated degradation of Cyclin A"/>
            <pathway-xref db="Reactome" id="R-RNO-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="Reactome" id="R-HSA-180336" name="SHC1 events in EGFR signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-5654227" name="Phospholipase C-mediated cascade, FGFR3"/>
            <pathway-xref db="Reactome" id="R-RNO-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-MMU-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-RNO-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-5213460" name="RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-MMU-212676" name="Dopamine Neurotransmitter Release Cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-3000171" name="Non-integrin membrane-ECM interactions"/>
            <pathway-xref db="Reactome" id="R-HSA-164378" name="PKA activation in glucagon signalling"/>
            <pathway-xref db="Reactome" id="R-HSA-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="Reactome" id="R-DRE-2995383" name="Initiation of Nuclear Envelope (NE) Reformation"/>
            <pathway-xref db="Reactome" id="R-HSA-8853333" name="Signaling by FGFR2 fusions"/>
            <pathway-xref db="Reactome" id="R-HSA-5674400" name="Constitutive Signaling by AKT1 E17K in Cancer"/>
            <pathway-xref db="Reactome" id="R-HSA-9014325" name="TICAM1,TRAF6-dependent induction of TAK1 complex"/>
            <pathway-xref db="Reactome" id="R-MMU-975144" name="IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"/>
            <pathway-xref db="Reactome" id="R-MMU-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-DME-114604" name="GPVI-mediated activation cascade"/>
            <pathway-xref db="Reactome" id="R-SPO-6781823" name="Formation of TC-NER Pre-Incision Complex"/>
            <pathway-xref db="Reactome" id="R-HSA-177504" name="Retrograde neurotrophin signalling"/>
            <pathway-xref db="Reactome" id="R-RNO-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-HSA-383280" name="Nuclear Receptor transcription pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-DME-450520" name="HuR (ELAVL1) binds and stabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-DRE-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-4641262" name="Disassembly of the destruction complex and recruitment of AXIN to the membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-SCE-2179392" name="EGFR Transactivation by Gastrin"/>
            <pathway-xref db="Reactome" id="R-BTA-2424491" name="DAP12 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-190370" name="FGFR1b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-3769402" name="Deactivation of the beta-catenin transactivating complex"/>
            <pathway-xref db="Reactome" id="R-DME-209209" name="Formation of the activated receptor complex"/>
            <pathway-xref db="Reactome" id="R-MMU-1253288" name="Downregulation of ERBB4 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-450385" name="Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"/>
            <pathway-xref db="Reactome" id="R-RNO-141444" name="Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"/>
            <pathway-xref db="Reactome" id="R-MMU-198693" name="AKT phosphorylates targets in the nucleus"/>
            <pathway-xref db="Reactome" id="R-HSA-6802948" name="Signaling by high-kinase activity BRAF mutants"/>
            <pathway-xref db="Reactome" id="R-CEL-438066" name="Unblocking of NMDA receptors, glutamate binding and activation"/>
            <pathway-xref db="Reactome" id="R-HSA-190372" name="FGFR3c ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-RNO-2500257" name="Resolution of Sister Chromatid Cohesion"/>
            <pathway-xref db="Reactome" id="R-RNO-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-6791226" name="Major pathway of rRNA processing in the nucleolus and cytosol"/>
            <pathway-xref db="Reactome" id="R-MMU-8847993" name="ERBB2 Activates PTK6 Signaling"/>
            <pathway-xref db="Reactome" id="R-DME-68875" name="Mitotic Prophase"/>
            <pathway-xref db="Reactome" id="R-RNO-198203" name="PI3K/AKT activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9665244" name="Resistance of ERBB2 KD mutants to sapitinib"/>
            <pathway-xref db="Reactome" id="R-MMU-5218920" name="VEGFR2 mediated vascular permeability"/>
            <pathway-xref db="Reactome" id="R-DDI-77075" name="RNA Pol II CTD phosphorylation and interaction with CE"/>
            <pathway-xref db="Reactome" id="R-HSA-912446" name="Meiotic recombination"/>
            <pathway-xref db="Reactome" id="R-MMU-9706374" name="FLT3 signaling through SRC family kinases"/>
            <pathway-xref db="Reactome" id="R-DME-418885" name="DCC mediated attractive signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-69541" name="Stabilization of p53"/>
            <pathway-xref db="Reactome" id="R-DRE-354192" name="Integrin signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-HSA-8876493" name="InlA-mediated entry of Listeria monocytogenes into host cells"/>
            <pathway-xref db="Reactome" id="R-DRE-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-HSA-912694" name="Regulation of IFNA signaling"/>
            <pathway-xref db="Reactome" id="R-DME-5607764" name="CLEC7A (Dectin-1) signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-190371" name="FGFR3b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-CEL-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-HSA-9006335" name="Signaling by Erythropoietin"/>
            <pathway-xref db="Reactome" id="R-SPO-9619229" name="Activation of RAC1 downstream of NMDARs"/>
            <pathway-xref db="Reactome" id="R-HSA-9669926" name="Nilotinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-RNO-6811558" name="PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-SPO-5628897" name="TP53 Regulates Metabolic Genes"/>
            <pathway-xref db="Reactome" id="R-RNO-389356" name="CD28 co-stimulation"/>
            <pathway-xref db="Reactome" id="R-CFA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-HSA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1358803" name="Downregulation of ERBB2:ERBB3 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-5663220" name="RHO GTPases Activate Formins"/>
            <pathway-xref db="Reactome" id="R-HSA-9652169" name="Signaling by MAP2K mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-8856825" name="Cargo recognition for clathrin-mediated endocytosis"/>
            <pathway-xref db="Reactome" id="R-DDI-187577" name="SCF(Skp2)-mediated degradation of p27/p21"/>
            <pathway-xref db="Reactome" id="R-DDI-69656" name="Cyclin A:Cdk2-associated events at S phase entry"/>
            <pathway-xref db="Reactome" id="R-SCE-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-GGA-5621575" name="CD209 (DC-SIGN) signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-399956" name="CRMPs in Sema3A signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-DDI-69200" name="Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes"/>
            <pathway-xref db="Reactome" id="R-GGA-442742" name="CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-6804760" name="Regulation of TP53 Activity through Methylation"/>
            <pathway-xref db="Reactome" id="R-DME-6785631" name="ERBB2 Regulates Cell Motility"/>
            <pathway-xref db="Reactome" id="R-DDI-9648002" name="RAS processing"/>
            <pathway-xref db="Reactome" id="R-MMU-8849471" name="PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"/>
            <pathway-xref db="Reactome" id="R-HSA-6788467" name="IL-6-type cytokine receptor ligand interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-177929" name="Signaling by EGFR"/>
            <pathway-xref db="Reactome" id="R-HSA-525793" name="Myogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-DME-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-MMU-9604323" name="Negative regulation of NOTCH4 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-8853334" name="Signaling by FGFR3 fusions in cancer"/>
            <pathway-xref db="Reactome" id="R-RNO-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-CEL-5675482" name="Regulation of necroptotic cell death"/>
            <pathway-xref db="Reactome" id="R-MMU-9706369" name="Negative regulation of FLT3"/>
            <pathway-xref db="Reactome" id="R-RNO-73776" name="RNA Polymerase II Promoter Escape"/>
            <pathway-xref db="Reactome" id="R-HSA-198765" name="Signalling to ERK5"/>
            <pathway-xref db="Reactome" id="R-DDI-381070" name="IRE1alpha activates chaperones"/>
            <pathway-xref db="MetaCyc" id="PWY-7769" name="phosalacine biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-9669917" name="Imatinib-resistant KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-1236382" name="Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"/>
            <pathway-xref db="Reactome" id="R-HSA-2173796" name="SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-354194" name="GRB2:SOS provides linkage to MAPK signaling for Integrins"/>
            <pathway-xref db="Reactome" id="R-RNO-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-1169408" name="ISG15 antiviral mechanism"/>
            <pathway-xref db="Reactome" id="R-HSA-442742" name="CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-5576892" name="Phase 0 - rapid depolarisation"/>
            <pathway-xref db="Reactome" id="R-HSA-450341" name="Activation of the AP-1 family of transcription factors"/>
            <pathway-xref db="Reactome" id="R-BTA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-BTA-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-RNO-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DME-201688" name="WNT mediated activation of DVL"/>
            <pathway-xref db="Reactome" id="R-MMU-73863" name="RNA Polymerase I Transcription Termination"/>
            <pathway-xref db="Reactome" id="R-HSA-9693928" name="Defective RIPK1-mediated regulated necrosis"/>
            <pathway-xref db="Reactome" id="R-MMU-2559585" name="Oncogene Induced Senescence"/>
            <pathway-xref db="Reactome" id="R-SPO-3371453" name="Regulation of HSF1-mediated heat shock response"/>
            <pathway-xref db="Reactome" id="R-HSA-167161" name="HIV Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-881907" name="Gastrin-CREB signalling pathway via PKC and MAPK"/>
            <pathway-xref db="Reactome" id="R-DDI-8854214" name="TBC/RABGAPs"/>
            <pathway-xref db="Reactome" id="R-HSA-8939236" name="RUNX1 regulates transcription of genes involved in differentiation of HSCs"/>
            <pathway-xref db="Reactome" id="R-DRE-1433559" name="Regulation of KIT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-162658" name="Golgi Cisternae Pericentriolar Stack Reorganization"/>
            <pathway-xref db="Reactome" id="R-DDI-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-DRE-2514859" name="Inactivation, recovery and regulation of the phototransduction cascade"/>
            <pathway-xref db="Reactome" id="R-BTA-5687128" name="MAPK6/MAPK4 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-MMU-8875555" name="MET activates RAP1 and RAC1"/>
            <pathway-xref db="Reactome" id="R-DRE-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-HSA-170984" name="ARMS-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DRE-3928663" name="EPHA-mediated growth cone collapse"/>
            <pathway-xref db="MetaCyc" id="PWY-8129" name="cell-surface glycoconjugate-linked phosphonate biosynthesis"/>
            <pathway-xref db="Reactome" id="R-DRE-9013149" name="RAC1 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-5654699" name="SHC-mediated cascade:FGFR2"/>
            <pathway-xref db="Reactome" id="R-DRE-416993" name="Trafficking of GluR2-containing AMPA receptors"/>
            <pathway-xref db="Reactome" id="R-SCE-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-MMU-430116" name="GP1b-IX-V activation signalling"/>
            <pathway-xref db="Reactome" id="R-SPO-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-HSA-211736" name="Stimulation of the cell death response by PAK-2p34"/>
            <pathway-xref db="Reactome" id="R-HSA-194306" name="Neurophilin interactions with VEGF and VEGFR"/>
            <pathway-xref db="Reactome" id="R-SPO-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-SPO-8934903" name="Receptor Mediated Mitophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-HSA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-MMU-9008059" name="Interleukin-37 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-DDI-180024" name="DARPP-32 events"/>
            <pathway-xref db="Reactome" id="R-DME-163615" name="PKA activation"/>
            <pathway-xref db="MetaCyc" id="PWY-7321" name="ecdysteroid metabolism (arthropods)"/>
            <pathway-xref db="Reactome" id="R-DRE-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-DDI-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-BTA-198765" name="Signalling to ERK5"/>
            <pathway-xref db="Reactome" id="R-MMU-3928664" name="Ephrin signaling"/>
            <pathway-xref db="Reactome" id="R-SCE-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-5676590" name="NIK--&gt;noncanonical NF-kB signaling"/>
            <pathway-xref db="Reactome" id="R-DDI-2465910" name="MASTL Facilitates Mitotic Progression"/>
            <pathway-xref db="Reactome" id="R-MMU-937072" name="TRAF6-mediated induction of TAK1 complex within TLR4 complex"/>
            <pathway-xref db="Reactome" id="R-XTR-674695" name="RNA Polymerase II Pre-transcription Events"/>
            <pathway-xref db="Reactome" id="R-DME-5218921" name="VEGFR2 mediated cell proliferation"/>
            <pathway-xref db="Reactome" id="R-DRE-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-SSC-2559582" name="Senescence-Associated Secretory Phenotype (SASP)"/>
            <pathway-xref db="Reactome" id="R-SPO-6796648" name="TP53 Regulates Transcription of DNA Repair Genes"/>
            <pathway-xref db="Reactome" id="R-HSA-5621480" name="Dectin-2 family"/>
            <pathway-xref db="Reactome" id="R-SSC-3214858" name="RMTs methylate histone arginines"/>
            <pathway-xref db="Reactome" id="R-HSA-5250924" name="B-WICH complex positively regulates rRNA expression"/>
            <pathway-xref db="Reactome" id="R-HSA-2892247" name="POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation"/>
            <pathway-xref db="Reactome" id="R-CFA-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DME-9648025" name="EML4 and NUDC in mitotic spindle formation"/>
            <pathway-xref db="Reactome" id="R-RNO-163615" name="PKA activation"/>
            <pathway-xref db="Reactome" id="R-DME-110523" name="TOR signaling pathway"/>
            <pathway-xref db="Reactome" id="R-MMU-6782135" name="Dual incision in TC-NER"/>
            <pathway-xref db="Reactome" id="R-HSA-445989" name="TAK1 activates NFkB by phosphorylation and activation of IKKs complex"/>
            <pathway-xref db="Reactome" id="R-MMU-391160" name="Signal regulatory protein family interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-450321" name="JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"/>
            <pathway-xref db="Reactome" id="R-CEL-445144" name="Signal transduction by L1"/>
            <pathway-xref db="Reactome" id="R-MMU-3899300" name="SUMOylation of transcription cofactors"/>
            <pathway-xref db="Reactome" id="R-HSA-8849474" name="PTK6 Activates STAT3"/>
            <pathway-xref db="Reactome" id="R-MMU-69273" name="Cyclin A/B1/B2 associated events during G2/M transition"/>
            <pathway-xref db="Reactome" id="R-CEL-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1250196" name="SHC1 events in ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-GGA-217106" name="Chk1-controlled and DNA-damage induced centrosome duplication"/>
            <pathway-xref db="Reactome" id="R-MMU-6785807" name="Interleukin-4 and Interleukin-13 signaling"/>
            <pathway-xref db="Reactome" id="R-SPO-203615" name="eNOS activation"/>
            <pathway-xref db="Reactome" id="R-RNO-4419969" name="Depolymerisation of the Nuclear Lamina"/>
            <pathway-xref db="Reactome" id="R-GGA-9031628" name="NGF-stimulated transcription"/>
            <pathway-xref db="Reactome" id="R-SCE-75953" name="RNA Polymerase II Transcription Initiation"/>
            <pathway-xref db="Reactome" id="R-DDI-3295583" name="TRP channels"/>
            <pathway-xref db="Reactome" id="R-DDI-2299718" name="Condensation of Prophase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-CEL-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-HSA-9702590" name="gilteritinib-resistant FLT3 mutants"/>
            <pathway-xref db="Reactome" id="R-DDI-5693565" name="Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"/>
            <pathway-xref db="Reactome" id="R-MMU-9034793" name="Activated NTRK3 signals through PLCG1"/>
            <pathway-xref db="Reactome" id="R-MMU-936440" name="Negative regulators of DDX58/IFIH1 signaling"/>
            <pathway-xref db="Reactome" id="R-MMU-1660517" name="Synthesis of PIPs at the late endosome membrane"/>
            <pathway-xref db="Reactome" id="R-RNO-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-RNO-202433" name="Generation of second messenger molecules"/>
            <pathway-xref db="Reactome" id="R-SPO-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-9013420" name="RHOU GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-HSA-76042" name="RNA Polymerase II Transcription Initiation And Promoter Clearance"/>
            <pathway-xref db="Reactome" id="R-SCE-165158" name="Activation of AKT2"/>
            <pathway-xref db="Reactome" id="R-HSA-8849472" name="PTK6 Down-Regulation"/>
            <pathway-xref db="Reactome" id="R-SCE-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-DDI-5696395" name="Formation of Incision Complex in GG-NER"/>
            <pathway-xref db="Reactome" id="R-GGA-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-CEL-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-HSA-9665233" name="Resistance of ERBB2 KD mutants to trastuzumab"/>
            <pathway-xref db="Reactome" id="R-RNO-1660661" name="Sphingolipid de novo biosynthesis"/>
            <pathway-xref db="Reactome" id="R-HSA-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-SPO-5674499" name="Negative feedback regulation of MAPK pathway"/>
            <pathway-xref db="Reactome" id="R-RNO-5632684" name="Hedgehog 'on' state"/>
            <pathway-xref db="Reactome" id="R-HSA-9669935" name="Signaling by juxtamembrane domain KIT mutants"/>
            <pathway-xref db="Reactome" id="R-HSA-975110" name="TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-2467813" name="Separation of Sister Chromatids"/>
            <pathway-xref db="Reactome" id="R-RNO-432722" name="Golgi Associated Vesicle Biogenesis"/>
            <pathway-xref db="Reactome" id="R-HSA-8948751" name="Regulation of PTEN stability and activity"/>
            <pathway-xref db="Reactome" id="R-HSA-975155" name="MyD88 dependent cascade initiated on endosome"/>
            <pathway-xref db="Reactome" id="R-HSA-422356" name="Regulation of insulin secretion"/>
            <pathway-xref db="Reactome" id="R-DRE-111933" name="Calmodulin induced events"/>
            <pathway-xref db="Reactome" id="R-HSA-2980766" name="Nuclear Envelope Breakdown"/>
            <pathway-xref db="Reactome" id="R-HSA-9009391" name="Extra-nuclear estrogen signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-877312" name="Regulation of IFNG signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-2029481" name="FCGR activation"/>
            <pathway-xref db="Reactome" id="R-DRE-420029" name="Tight junction interactions"/>
            <pathway-xref db="Reactome" id="R-MMU-209543" name="p75NTR recruits signalling complexes"/>
            <pathway-xref db="Reactome" id="R-DRE-5668599" name="RHO GTPases Activate NADPH Oxidases"/>
            <pathway-xref db="Reactome" id="R-DRE-5578775" name="Ion homeostasis"/>
            <pathway-xref db="Reactome" id="R-MMU-2514853" name="Condensation of Prometaphase Chromosomes"/>
            <pathway-xref db="Reactome" id="R-DRE-418594" name="G alpha (i) signalling events"/>
            <pathway-xref db="Reactome" id="R-GGA-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-SPO-9020702" name="Interleukin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-8980692" name="RHOA GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-RNO-2028269" name="Signaling by Hippo"/>
            <pathway-xref db="Reactome" id="R-SPO-6798695" name="Neutrophil degranulation"/>
            <pathway-xref db="Reactome" id="R-DME-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-GGA-1295596" name="Spry regulation of FGF signaling"/>
            <pathway-xref db="Reactome" id="R-RNO-69478" name="G2/M DNA replication checkpoint"/>
            <pathway-xref db="Reactome" id="R-CEL-2871837" name="FCERI mediated NF-kB activation"/>
            <pathway-xref db="Reactome" id="R-HSA-9032845" name="Activated NTRK2 signals through CDK5"/>
            <pathway-xref db="Reactome" id="R-MMU-9013404" name="RAC2 GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SSC-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-SCE-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="MetaCyc" id="PWY-5129" name="sphingolipid biosynthesis (plants)"/>
            <pathway-xref db="Reactome" id="R-GGA-1227986" name="Signaling by ERBB2"/>
            <pathway-xref db="Reactome" id="R-RNO-163680" name="AMPK inhibits chREBP transcriptional activation activity"/>
            <pathway-xref db="Reactome" id="R-CEL-75153" name="Apoptotic execution phase"/>
            <pathway-xref db="Reactome" id="R-CEL-380972" name="Energy dependent regulation of mTOR by LKB1-AMPK"/>
            <pathway-xref db="Reactome" id="R-CEL-389359" name="CD28 dependent Vav1 pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-918233" name="TRAF3-dependent IRF activation pathway"/>
            <pathway-xref db="Reactome" id="R-CEL-170968" name="Frs2-mediated activation"/>
            <pathway-xref db="Reactome" id="R-HSA-2122947" name="NOTCH1 Intracellular Domain Regulates Transcription"/>
            <pathway-xref db="Reactome" id="R-DRE-373753" name="Nephrin family interactions"/>
            <pathway-xref db="Reactome" id="R-DRE-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-193648" name="NRAGE signals death through JNK"/>
            <pathway-xref db="Reactome" id="R-RNO-187042" name="TRKA activation by NGF"/>
            <pathway-xref db="Reactome" id="R-SCE-9013405" name="RHOD GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DME-168638" name="NOD1/2 Signaling Pathway"/>
            <pathway-xref db="Reactome" id="R-DRE-180292" name="GAB1 signalosome"/>
            <pathway-xref db="Reactome" id="R-RNO-381676" name="Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"/>
            <pathway-xref db="Reactome" id="R-MMU-6804756" name="Regulation of TP53 Activity through Phosphorylation"/>
            <pathway-xref db="Reactome" id="R-MMU-1433557" name="Signaling by SCF-KIT"/>
            <pathway-xref db="Reactome" id="R-CEL-983231" name="Factors involved in megakaryocyte development and platelet production"/>
            <pathway-xref db="Reactome" id="R-HSA-9013407" name="RHOH GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-SCE-1660514" name="Synthesis of PIPs at the Golgi membrane"/>
            <pathway-xref db="Reactome" id="R-MMU-399955" name="SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"/>
            <pathway-xref db="Reactome" id="R-GGA-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-DRE-9032759" name="NTRK2 activates RAC1"/>
            <pathway-xref db="Reactome" id="R-HSA-5654733" name="Negative regulation of FGFR4 signaling"/>
            <pathway-xref db="Reactome" id="R-CEL-69473" name="G2/M DNA damage checkpoint"/>
            <pathway-xref db="Reactome" id="R-DRE-912631" name="Regulation of signaling by CBL"/>
            <pathway-xref db="Reactome" id="R-HSA-2672351" name="Stimuli-sensing channels"/>
            <pathway-xref db="Reactome" id="R-MMU-9027276" name="Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"/>
            <pathway-xref db="Reactome" id="R-CEL-2871796" name="FCERI mediated MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-450302" name="activated TAK1 mediates p38 MAPK activation"/>
            <pathway-xref db="Reactome" id="R-DDI-1632852" name="Macroautophagy"/>
            <pathway-xref db="Reactome" id="R-HSA-373752" name="Netrin-1 signaling"/>
            <pathway-xref db="Reactome" id="R-DRE-380320" name="Recruitment of NuMA to mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-RNO-1257604" name="PIP3 activates AKT signaling"/>
            <pathway-xref db="Reactome" id="R-SSC-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-CEL-8863795" name="Downregulation of ERBB2 signaling"/>
            <pathway-xref db="Reactome" id="R-BTA-1538133" name="G0 and Early G1"/>
            <pathway-xref db="Reactome" id="R-RNO-375165" name="NCAM signaling for neurite out-growth"/>
            <pathway-xref db="Reactome" id="R-MMU-5654732" name="Negative regulation of FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-DME-4086398" name="Ca2+ pathway"/>
            <pathway-xref db="Reactome" id="R-HSA-9634285" name="Constitutive Signaling by Overexpressed ERBB2"/>
            <pathway-xref db="Reactome" id="R-DME-109704" name="PI3K Cascade"/>
            <pathway-xref db="Reactome" id="R-DME-390098" name="Phosphorylation-dependent inhibition of YKI"/>
            <pathway-xref db="Reactome" id="R-MMU-5627123" name="RHO GTPases activate PAKs"/>
            <pathway-xref db="Reactome" id="R-SCE-9013026" name="RHOB GTPase cycle"/>
            <pathway-xref db="Reactome" id="R-DRE-418592" name="ADP signalling through P2Y purinoceptor 1"/>
            <pathway-xref db="Reactome" id="R-DME-6804116" name="TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"/>
            <pathway-xref db="Reactome" id="R-DME-195253" name="Degradation of beta-catenin by the destruction complex"/>
            <pathway-xref db="Reactome" id="R-MMU-380259" name="Loss of Nlp from mitotic centrosomes"/>
            <pathway-xref db="Reactome" id="R-CEL-176408" name="Regulation of APC/C activators between G1/S and early anaphase"/>
            <pathway-xref db="Reactome" id="R-DRE-389513" name="CTLA4 inhibitory signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5654706" name="FRS-mediated FGFR3 signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-392451" name="G beta:gamma signalling through PI3Kgamma"/>
            <pathway-xref db="Reactome" id="R-HSA-6782210" name="Gap-filling DNA repair synthesis and ligation in TC-NER"/>
            <pathway-xref db="Reactome" id="R-DRE-190377" name="FGFR2b ligand binding and activation"/>
            <pathway-xref db="Reactome" id="R-DME-5099900" name="WNT5A-dependent internalization of FZD4"/>
            <pathway-xref db="Reactome" id="R-HSA-5357786" name="TNFR1-induced proapoptotic signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-5627117" name="RHO GTPases Activate ROCKs"/>
            <pathway-xref db="Reactome" id="R-BTA-8853659" name="RET signaling"/>
            <pathway-xref db="Reactome" id="R-HSA-1236394" name="Signaling by ERBB4"/>
         