Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_049875912.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049872259.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049882629.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049864883.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049868748.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049866075.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049880045.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049876090.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049885464.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049875564.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_049881595.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049868807.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049872984.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response"
XP_049882515.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876203.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049868267.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049887808.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049879984.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049881849.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049873675.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049883361.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049879061.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049883706.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049879492.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049876962.1	5	MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_049865478.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873118.1	10	KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_049873075.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049875121.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049879983.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049881187.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-975634	"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"Chylomicron assembly";"Chylomicron clearance";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Retinoid metabolism and transport"
XP_049873869.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049878225.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049868427.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049870635.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049867379.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049871951.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049874041.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049881993.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049883828.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049874580.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049865040.1	10	Reactome: R-HSA-6807505;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA polymerase II transcribes snRNA genes";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049885974.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049867968.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049871170.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-5662702	"Ion transport by P-type ATPases";"Melanin biosynthesis"
XP_049865799.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049876467.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_049866152.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049888096.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049876118.1	3	KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_049882609.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049879748.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2	"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism"
XP_049882321.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049880414.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049885303.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049876186.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049888202.1	11	MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-5381;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5695	"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation"
XP_049876921.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049873543.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519	"Generic Transcription Pathway";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression"
XP_049878134.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049880724.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049872070.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049871354.1	3	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049869600.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049880162.1	10	Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72731;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Translation initiation complex formation";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Recycling of eIF2:GDP";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049867310.1	8	MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1	"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis"
XP_049887242.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049881446.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049866520.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_049879353.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_049883198.1	18	KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-163765;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-6728;Reactome: R-HSA-6798695	"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Neutrophil degranulation"
XP_049870054.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049881449.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049884424.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049879759.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2	"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism"
XP_049887371.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001	"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism"
XP_049866913.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049883163.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049867775.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_049881376.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049884908.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938	"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)"
XP_049873394.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424	"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling"
XP_049867380.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049880417.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191	"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC"
XP_049887366.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049865343.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_049874782.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049878626.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049884808.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049876848.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_049866730.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049880125.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-3821	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification"
XP_049865572.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049872196.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049871307.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049885825.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049888037.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049866412.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049875095.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)"
XP_049865884.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049882219.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049880231.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049867694.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_049876673.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049888231.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049869224.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049875265.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_049883384.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5857	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049885894.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049864889.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049883368.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_049873619.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049872022.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049882961.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_049878055.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway"
XP_049874866.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049880372.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049872783.1	6	KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049866193.1	7	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049865789.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049872754.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049879975.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049879674.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049882286.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_049883954.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049881702.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049887803.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049874033.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049874544.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049871485.1	22	MetaCyc: PWY-7606;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7049;MetaCyc: PWY-7727;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-5353	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"
XP_049867639.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049866308.1	4	KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I"
XP_049876031.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049878412.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049885133.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049887633.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049877341.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049868967.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700	"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_049865394.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049882376.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049879774.1	11	KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049888006.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_049871314.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_049884480.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881827.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049881806.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049877326.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049884882.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049871068.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049879603.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049874640.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049881118.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049877449.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049871631.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049877277.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317	"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_049876259.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049881261.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866897.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049871547.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049887228.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049886161.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887997.1	5	KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049887492.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049883927.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049871218.1	9	Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535	"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer"
XP_049866406.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_049880936.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049865864.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049880089.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity"
XP_049873046.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049870164.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_049883161.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049888139.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049868249.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049873491.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049887525.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049869534.1	7	Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_049877697.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_049880378.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_049881609.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049866388.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049873641.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049878114.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049876055.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049875924.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049872082.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049881184.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049869802.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_049869824.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049882597.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049871998.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049877950.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049873156.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167246	"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049866687.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049878063.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049869197.1	8	MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7734;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_049877029.1	14	Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_049879401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049881368.1	4	Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874	"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I"
XP_049880733.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049866575.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049867393.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877575.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049888236.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049868900.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049879710.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049880040.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049866393.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_049875695.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049884655.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049866151.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_049881432.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049868220.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049878750.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049886288.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_049877412.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_049865903.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049872939.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049865065.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049866737.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_049877324.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049882377.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049879792.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049875032.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049883172.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_049887879.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276	"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Gap junction assembly";"Separation of Sister Chromatids";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_049885114.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049879995.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049870276.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049880302.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049877327.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049878953.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049881743.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049885809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049871305.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049883520.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_049872204.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049871585.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049869332.1	33	Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236	"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049886015.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604	"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling"
XP_049873813.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049872536.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_049867265.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049878645.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_049882985.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049870617.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_049882508.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049884482.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049885169.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049877635.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049882078.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049880699.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"ATP biosynthesis";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Photosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_049888110.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049865553.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_049884693.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049871606.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049872696.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049865801.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_049887464.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049878279.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_049878936.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049869428.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049869302.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049866721.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049884047.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049872418.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049876662.1	2	Reactome: R-HSA-177128;Reactome: R-HSA-177135	"Conjugation of salicylate with glycine";"Conjugation of benzoate with glycine"
XP_049887927.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049876018.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049879161.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593	"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity"
XP_049887489.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049886001.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884828.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049883335.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887234.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_049876167.1	42	KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6435;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-6946;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7779;MetaCyc: PWY-7654;MetaCyc: PWY-5138;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5109;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-6863;KEGG: 00903+4.2.1.17	"beta-Alanine metabolism";"Geraniol degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Propanoate metabolism";"Butanoate metabolism";"2-methylpropene degradation";"Fatty acid degradation";"Aminobenzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fermentation to 2-methylbutanoate";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to hexanol (engineered)";"Limonene and pinene degradation"
XP_049869524.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049880504.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049883606.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_049871387.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_049867051.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049883697.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049865249.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049872264.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-6708	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_049884289.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_049872822.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049868979.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757	"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of TP53 Degradation"
XP_049867640.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049873984.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049870257.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049880539.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049884641.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049866230.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_049879456.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049868027.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049874802.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049882423.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049871466.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049886779.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_049874001.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_049880947.1	9	MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation"
XP_049882594.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049868467.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049870390.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049879228.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049869316.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049872802.1	4	Reactome: R-HSA-4755609;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_049880502.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049884439.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049865220.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049881813.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049883551.1	11	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-5689880;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Ub-specific processing proteases";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Promoter Escape"
XP_049875024.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049876111.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049879800.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049869491.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049865442.1	3	MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3	"Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism"
XP_049882175.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049882974.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097	"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049865772.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049880892.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049867921.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972	"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049869235.1	4	Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409	"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049867412.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade"
XP_049876827.1	13	Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5689877;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695	"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"HSF1 activation";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Josephin domain DUBs";"Protein methylation";"Neutrophil degranulation"
XP_049865183.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049865126.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049867027.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049882672.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049878246.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049876084.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049878854.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049865151.1	7	Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166	"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PG";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_049878081.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_049868918.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_049866343.1	6	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network"
XP_049880224.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049868007.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049865788.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_049868898.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049880739.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049887670.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049872924.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049879753.1	11	KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049872064.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049878138.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049871662.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049884327.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_049873914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049878295.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049868779.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-429947;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049868475.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049887642.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049867075.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049872050.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049885839.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049879413.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049867319.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049878706.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049888145.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083	"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions"
XP_049875806.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049868995.1	10	Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-917729	"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Ub-specific processing proteases";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049865689.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049876920.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049868724.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049865149.1	7	Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485	"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Ether lipid metabolism";"Role of phospholipids in phagocytosis"
XP_049869253.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049885768.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049882505.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879432.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049886101.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3	"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism"
XP_049886158.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049877149.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049875056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049874622.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049885510.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049879157.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_049884227.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049870322.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049867776.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation"
XP_049871463.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049866952.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049866533.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049866763.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_049869689.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049876221.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049884728.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049866683.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049872025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049878662.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049867766.1	18	Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-8953750;Reactome: R-HSA-1221632;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648	"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Protein ubiquitination";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional Regulation by E2F6";"Meiotic synapsis";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049879804.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049877245.1	13	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902	"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049882519.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882310.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_049870417.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424	"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling"
XP_049872446.1	3	Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049875552.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049866165.1	9	KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)"
XP_049885621.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866252.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049883839.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049876122.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049879817.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049887260.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049870406.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049877884.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049886636.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049867684.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_049867474.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_049866095.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049878098.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049876261.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049888047.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882975.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-171007	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"NOD1/2 Signaling Pathway";"p38MAPK events"
XP_049882726.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049879016.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049883824.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049884509.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049866551.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049871476.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049865421.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049882631.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049884226.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873299.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049879742.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049869159.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_049869599.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_049869303.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049874719.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049874686.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049879798.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049882329.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049873420.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049874002.1	3	Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_049865831.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049874539.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events"
XP_049886952.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049878415.1	4	KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_049886235.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049876427.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049872698.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049866264.1	5	KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122	"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_049882327.1	9	MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis"
XP_049872542.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049868030.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048	"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049879802.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049881515.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-163359	"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation"
XP_049885987.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049869475.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885	"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins"
XP_049867405.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049866437.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180910	"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs"
XP_049880044.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049880028.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication"
XP_049874546.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_049874691.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049882552.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_049871814.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049876068.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049880551.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049870204.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_049878000.1	11	MetaCyc: PWY-6859;MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7560;MetaCyc: PWY-6383;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-922	"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_049865889.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049884662.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049885190.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049866554.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049866325.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049865010.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049865919.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049876067.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049878068.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049884046.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049876908.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II"
XP_049880393.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_049882520.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865218.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049876270.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049868576.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049872034.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_049868780.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_049881287.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Dual incision in TC-NER"
XP_049879740.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049887886.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049873208.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049879153.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5628897	"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes"
XP_049876563.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049868657.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049865045.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876567.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049881942.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants"
XP_049882712.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049870323.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049888091.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049879973.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049871289.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis"
XP_049876932.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_049873606.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049877402.1	4	Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_049870645.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049871665.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049866890.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049881455.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049872055.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049866436.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_049884801.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049867288.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049880349.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040	"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_049883823.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049868654.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049872511.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873212.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049877817.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049873840.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"LDL clearance"
XP_049878846.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873674.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049871922.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049867869.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_049866948.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049870349.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049875603.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049877698.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_049877038.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049870765.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049875011.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism"
XP_049880031.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049865574.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049873220.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049876185.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049868890.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049881981.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049864891.1	6	MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_049869764.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_049885969.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049876772.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049866522.1	3	KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456	"Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid"
XP_049879624.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049864916.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049869975.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049865710.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049884387.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_049886268.1	24	Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-202040	"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G-protein activation"
XP_049873557.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049885110.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049867435.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_049880497.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049879340.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049881958.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049887597.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049869725.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049865041.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_049887203.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III"
XP_049879497.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049884646.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049866548.1	42	MetaCyc: PWY-6435;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-6946;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7654;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-5109;MetaCyc: PWY-6863;KEGG: 00903+4.2.1.17	"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid salvage";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"Phenylalanine metabolism";"beta-Alanine metabolism";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"2-methylpropene degradation";"Tryptophan metabolism";"Propanoate metabolism";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Fatty acid degradation";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Limonene and pinene degradation"
XP_049887206.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453	"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis"
XP_049881842.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049874639.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049883608.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049879004.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049869696.1	58	KEGG: 00281+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-5177;Reactome: R-HSA-77310;Reactome: R-HSA-77346;MetaCyc: PWY-6946;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-7779;Reactome: R-HSA-77348;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77285;MetaCyc: PWY-7216;KEGG: 00930+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6863;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-6944;MetaCyc: PWY-5109	"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"beta-Alanine metabolism";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"Fatty acid degradation";"Acyl chain remodeling of CL";"alpha-Linolenic acid metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"2-methylpropene degradation";"Butanoate metabolism";"Propanoate metabolism";"Tryptophan metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Caprolactam degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Caprolactam degradation";"Aminobenzoate degradation";"Lysine degradation";"Benzoate degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Androstenedione degradation";"Fermentation to 2-methylbutanoate"
XP_049880597.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049879770.1	11	MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5	"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049865601.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049877915.1	2	KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19	"Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism"
XP_049878558.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049868922.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049882707.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049885078.1	13	Reactome: R-HSA-9027277;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-2029485	"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"DAP12 signaling";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis"
XP_049883698.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049867415.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049871526.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049882504.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883477.1	11	MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_049879537.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049873496.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049867940.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049866515.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879964.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885568.1	7	MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049865142.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
YP_010449127.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049887004.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049872942.1	12	KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;MetaCyc: PWY-6121	"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049871994.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049874496.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_049872699.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049882555.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049866726.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049865477.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_049874458.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_049874865.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049879864.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049886170.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049873076.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_049882503.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876314.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049867328.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049885171.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049871801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874377.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-6282	"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)"
XP_049875518.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049876076.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049882075.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049867506.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049872023.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation"
XP_049885718.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049870639.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049871830.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_049879123.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049884288.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_049887804.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049868743.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_049881464.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049870110.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049881322.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049867788.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049867041.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049883370.1	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049884966.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049887438.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789	"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_049873537.1	3	Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4	"Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049871586.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049883873.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049881997.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049885249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049883154.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049875840.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049887889.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425	"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_049879512.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695	"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Neutrophil degranulation"
XP_049877743.1	17	Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048	"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_049867174.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049876510.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049871317.1	5	MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism"
XP_049879535.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049866883.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049870634.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049881353.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049881844.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049876313.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049886353.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049871452.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049865064.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049880513.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049887503.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049885115.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868505.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049870378.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049883844.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049888016.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_049867847.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049875795.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_049879749.1	11	MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5	"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049866319.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049882090.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049868834.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR"
XP_049880198.1	7	MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism"
XP_049873199.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049884692.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049873060.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_049873456.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049883649.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049876954.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049866893.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_049869412.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049875749.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049884539.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049872027.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049874009.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049882084.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049870330.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049879244.1	3	Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049884660.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049867778.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049870281.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7664;MetaCyc: PWY-5973	"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis"
XP_049866461.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049880550.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049879467.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049880332.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049887149.1	20	Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801	"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049867946.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049871131.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_049865071.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049885656.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_049874634.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049875314.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723	"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation"
XP_049875979.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049866199.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049883027.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049867313.1	8	MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4983;Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5154	"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049872056.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049883047.1	42	Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886	"HATs acetylate histones";"Cleavage of the damaged purine";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_049869688.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049865085.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049867757.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049871587.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049865887.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049865528.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049880520.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049868340.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_049885395.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049878705.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049866898.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049883170.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049880623.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_049884791.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049884476.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049882371.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049888129.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049885369.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"HCMV Early Events";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport"
XP_049873245.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049881340.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049867026.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887284.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049866731.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049872058.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168	"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049885654.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884763.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049871469.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049873968.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination"
XP_049867042.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049875026.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049882060.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049871287.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049878092.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049868855.1	7	MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism"
XP_049884637.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883178.1	19	Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-202733;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828	"Chylomicron clearance";"Chylomicron assembly";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Scavenging by Class F Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Retinoid metabolism and transport";"VLDL clearance";"Clathrin-mediated endocytosis"
XP_049885671.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049871217.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049865780.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_049877511.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880713.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_049867998.1	14	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-399997;Reactome: R-HSA-4086398;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;Reactome: R-HSA-418217	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"Ca2+ pathway";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"G beta:gamma signalling through PLC beta"
XP_049884658.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_049873768.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049873644.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049868725.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049880049.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049886434.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-201688	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL"
XP_049886239.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049867322.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049881548.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049869008.1	10	Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-917729	"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049866845.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049873412.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049877947.1	8	Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049878467.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049869883.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049877609.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_049887014.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"HCMV Early Events";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_049888206.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_049878814.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049873591.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6	"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism"
XP_049878123.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049885668.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation"
XP_049871950.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049887491.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049880580.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_049884673.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049880843.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_049876468.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049874798.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049886183.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_049881810.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049877641.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049874353.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887406.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049869500.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049883533.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049868616.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049884427.1	33	Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377	"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins"
XP_049882560.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883705.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049883176.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-6811436	"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049880634.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049875683.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049869406.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049868717.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049877334.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049875870.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049872315.1	8	KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049887831.1	18	KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1	"Phenylalanine metabolism";"Sulfolactate degradation III";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism"
XP_049865512.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049883536.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_049872626.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049874551.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201	"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049877853.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049881367.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049865877.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049887890.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049880507.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049869680.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049880766.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253	"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Orc1 removal from chromatin";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex"
XP_049871501.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049880029.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885930.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_049865338.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049873127.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049871445.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049868413.1	18	MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Pyruvate metabolism";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)"
XP_049868487.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_049880238.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049884919.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049867465.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049883362.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049878072.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049883019.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049877506.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880405.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049878025.1	7	KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation"
XP_049865690.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049867028.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049887733.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049884785.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_049881934.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-72165	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Dual incision in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_049873518.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049879103.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049880406.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049879587.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049867145.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3	"UMP biosynthesis I";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_049873392.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_049868805.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049879018.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049881172.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049873937.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049873395.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_049883511.1	42	Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-69473	"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"HCMV Late Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"HATs acetylate histones";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Meiotic synapsis";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint"
XP_049885638.1	12	MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Stachyose degradation";"Glycogen synthesis";"Galactose metabolism"
XP_049882404.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049876106.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049882502.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866900.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049886297.1	10	KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-6142	"Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049881847.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049873296.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049864831.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_049884987.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-9627069	"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity"
XP_049865649.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_049879064.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049870945.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049879388.1	19	MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;Reactome: R-HSA-380320;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7224	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Drug metabolism - other enzymes";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage"
XP_049877580.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_049874610.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049886977.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049874659.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049868964.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049885401.1	3	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049865905.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049872033.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049872287.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049868459.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_049878016.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049866750.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049886160.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887024.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_049878931.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049877507.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049879274.1	10	MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5892;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-5839	"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis"
XP_049886275.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049876039.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049879414.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866324.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049875166.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049875093.1	16	Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-201722	"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex"
XP_049873187.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049886425.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876071.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049886241.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049886100.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_049882514.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049871601.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049880653.1	6	MetaCyc: PWY-5514;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_049870405.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_049873664.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049866550.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_049873985.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049883614.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049885014.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049874178.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049876168.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049879151.1	4	KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_049880331.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049865625.1	8	MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754	"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate"
XP_049872191.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049872192.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049875647.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049870288.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_049884191.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_049872289.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049880960.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049878021.1	7	Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17	"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis"
XP_049874672.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049872707.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049875953.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049866529.1	18	Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-71403;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71064;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;KEGG: 00620+1.8.1.4;Reactome: R-HSA-70268;MetaCyc: PWY-5046;KEGG: 00260+1.8.1.4;KEGG: 00020+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00280+1.8.1.4;KEGG: 00380+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-389661	"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Lysine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine, serine and threonine metabolism";"Citrate cycle (TCA cycle)";"Glycine degradation";"Valine, leucine and isoleucine degradation";"Tryptophan metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation"
XP_049881650.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049882564.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049881128.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049876689.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_049885250.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881263.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868552.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_049874851.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049883686.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874804.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049869051.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049871386.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049865794.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_049867477.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049873162.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_049885617.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049872716.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049882088.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_049877404.1	4	Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_049866580.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis"
XP_049873088.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6783310;Reactome: R-HSA-606279;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation"
XP_049865221.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049868100.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049873579.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049872943.1	6	MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;Reactome: R-HSA-196780	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism"
XP_049887229.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049883018.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049880817.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049883832.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049882061.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049872863.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049881630.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049883334.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049869596.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_049875373.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_049881815.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049886166.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049867547.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049878243.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049866326.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049882032.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049878417.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049875649.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO";"Hedgehog 'off' state"
XP_049886034.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_049873583.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation"
XP_049866309.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049879254.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_049878103.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049875467.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_049878385.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_049871539.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049875613.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049865318.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049865035.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_049877851.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049878866.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049885904.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049872080.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049869950.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867758.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049883171.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049865584.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049865620.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049883360.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049872819.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049868474.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_049873294.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049886000.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049880059.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_049879747.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049876900.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049879272.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5892	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis"
XP_049868648.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_049873078.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049878099.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049867783.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-451308	"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor"
XP_049887008.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049874895.1	6	KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_049870329.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049870165.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_049874054.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly"
XP_049874158.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049880823.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049878730.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049877508.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049865259.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049882876.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049872532.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049867146.1	7	MetaCyc: PWY-5686;MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7790;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791	"UMP biosynthesis I";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_049882097.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049867037.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049870126.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex"
XP_049881268.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_049888040.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049880961.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880890.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049882565.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882279.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_049882733.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049873211.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049866772.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1592389	"Neutrophil degranulation";"Activation of Matrix Metalloproteinases"
XP_049867831.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_049866708.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287	"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery"
XP_049880999.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049876268.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_049883892.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_049867709.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049871306.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049885651.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049887467.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049869667.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049873816.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049869734.1	15	MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism"
XP_049869665.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049881139.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049867030.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049874637.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049878020.1	7	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315	"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol"
XP_049873546.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049871066.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049878056.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-6811558	"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_049883647.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049876330.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049885143.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049877832.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation"
XP_049888238.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049883365.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6708	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_049887965.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049867693.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049883696.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049881341.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049874797.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049869496.1	25	Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8939243;Reactome: R-HSA-9018519;Reactome: R-HSA-8939242;Reactome: R-HSA-8941333;Reactome: R-HSA-8951911;Reactome: R-HSA-8940973;Reactome: R-HSA-8877330;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245;Reactome: R-HSA-8941284;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8939256;Reactome: R-HSA-8941332;Reactome: R-HSA-8941326;Reactome: R-HSA-8939247;Reactome: R-HSA-8949275;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates osteoblast differentiation";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity"
XP_049875841.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111458	"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome"
XP_049880588.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049875247.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049879261.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049868950.1	17	Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756	"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation"
XP_049873292.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_049885157.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_049886401.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049869794.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049874723.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_049868209.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700	"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling"
XP_049881955.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_049879515.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049873137.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049869345.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049878202.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049882743.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049887726.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110312	"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1"
XP_049877070.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049881110.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049877809.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-432142	"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL"
XP_049866924.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_049880392.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_049871459.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049875555.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049884106.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049885821.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049866344.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_049881780.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049870099.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049867682.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049887798.1	4	KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049865213.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049887640.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049881600.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049880384.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049886285.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049881795.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049877540.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049881048.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049874650.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049880594.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_049868692.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_049888092.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049874469.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_049882543.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459	"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049868777.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_049873194.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049879936.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049866623.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049871737.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049873577.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049876863.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049885631.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049879271.1	10	MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-5839;MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163	"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049885635.1	12	MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9	"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Stachyose degradation";"Glycogen synthesis";"Galactose metabolism"
XP_049875091.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554	"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049885113.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049869006.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-917729	"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049866799.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049878573.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049869015.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049876139.1	6	MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_049879295.1	14	Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924	"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Macroautophagy";"Intraflagellar transport"
XP_049880549.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_049880303.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049874042.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_049865202.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_049888162.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine metabolism";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049875771.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049885911.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049867251.1	11	Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-210455	"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism"
XP_049882513.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865621.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049875925.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049874081.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049881070.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049870051.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049871804.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049876520.1	19	KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-71403;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5690	"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)"
XP_049885135.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049881486.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049871018.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_049883826.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_049869392.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049882002.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049869765.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_049875045.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049876691.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049867230.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049881023.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049867657.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049871446.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049880434.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_049887493.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049872053.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049873648.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2"
XP_049866268.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049876930.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation"
XP_049868039.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_049870842.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049885753.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049873021.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049865583.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_049887903.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_049884708.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049886971.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_049867368.1	57	Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-9604323	"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling"
XP_049872697.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_049886469.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049867143.1	4	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686	"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_049874543.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization"
XP_049873899.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049878141.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049868854.1	7	MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049870794.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049873423.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049865115.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049864921.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049873224.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049878892.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049884526.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade"
XP_049877554.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly"
XP_049876080.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049873289.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_049876247.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049872412.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_049870443.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_049865465.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868261.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692	"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity"
XP_049869964.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle"
XP_049886098.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)"
XP_049868509.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049866563.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049878210.1	6	MetaCyc: PWY-5097;MetaCyc: PWY-2941;KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2942;MetaCyc: PWY-8088	"L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Lysine biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis III";"Dipicolinate biosynthesis"
XP_049871457.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049877092.1	3	KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17	"Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism"
XP_049883735.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049880218.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049869346.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049880371.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049869315.1	7	Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049873482.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049875406.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049874836.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049878856.1	31	MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-5366;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-5971	"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Fatty acid biosynthesis";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_049876554.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049872521.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049873517.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049864982.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049869473.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049875008.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_049880377.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049874734.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049875403.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049875214.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049887065.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049865454.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049886208.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049887236.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049885945.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049872376.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049888135.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_049876263.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049873062.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049883506.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049883700.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049874758.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049864849.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049870767.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus"
XP_049874638.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867186.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_049884717.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049870335.1	15	MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049867177.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049888201.1	11	MetaCyc: PWY-6608;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-7821;MetaCyc: PWY-5695;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5	"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism"
XP_049886381.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049878890.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049885994.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049877289.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049872882.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049873232.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862	"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK"
XP_049865034.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_049867381.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049868504.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049879962.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049866635.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049887335.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049877888.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049871886.1	11	Reactome: R-HSA-168138;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;MetaCyc: PWY-6352;Reactome: R-HSA-109704;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517	"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"3-phosphoinositide biosynthesis";"PI3K Cascade";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane"
XP_049874066.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049869530.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049865453.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049869635.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport"
XP_049866549.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049888174.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_049869543.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049881561.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049875176.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_049865004.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049876914.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_049864951.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049877702.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049880560.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_049869448.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049884643.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049878413.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049870174.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_049887661.1	7	KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-46;MetaCyc: PWY-4984;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"Canavanine degradation";"Arginine biosynthesis";"Urea cycle"
XP_049875867.1	20	KEGG: 04926+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"Relaxin signaling pathway";"mTOR signalling";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_049875781.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049871581.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049870437.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898	"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III"
XP_049882390.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_049876058.1	8	Reactome: R-HSA-4086398;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-8856825;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-5099900	"Ca2+ pathway";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"WNT5A-dependent internalization of FZD4"
XP_049885788.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-601	"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan"
XP_049884805.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049886038.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049875007.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049871568.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049866517.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049880558.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I"
XP_049874385.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049874365.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049884906.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049882954.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459	"HCMV Late Events";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Meiotic synapsis";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049883155.1	11	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"Human papillomavirus infection"
XP_049882526.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049877224.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049875864.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049875719.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_049866303.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049869806.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049875292.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049880725.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049865547.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-2467813	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids"
XP_049884661.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049881094.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049877973.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049875401.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049867680.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_049867467.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049866516.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049884221.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881811.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_049886173.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049880355.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-418555	"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events"
XP_049883382.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049865599.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049881256.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867287.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_049883756.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-3385	"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PE";"Choline biosynthesis I"
XP_049880697.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049874957.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_049880364.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_049867175.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049886278.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049880189.1	7	MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism"
XP_049875442.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049885797.1	12	MetaCyc: PWY-801;MetaCyc: PWY-2821;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-601	"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan"
XP_049874203.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049873717.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049883125.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049883733.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049865631.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049885562.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049873371.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_049878829.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049879865.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049879501.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I"
XP_049868008.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049868972.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9022692	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity"
XP_049879235.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049876059.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_049865141.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049868296.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049885979.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049867376.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049881254.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049880514.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049884147.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887837.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049870668.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049882731.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049872611.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049879205.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049873022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865660.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049864867.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049871192.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049873804.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049869158.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_049868703.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864915.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049887795.1	32	Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167158	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex"
XP_049885461.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049866617.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049873163.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_049878686.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049877371.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049879252.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049866694.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049871255.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_049884472.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049876171.1	42	MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7654;MetaCyc: PWY-7779;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-6946;MetaCyc: PWY-7606;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-6944;MetaCyc: PWY-5109;MetaCyc: PWY-6863;KEGG: 00903+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00627+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35	"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"2-methylpropene degradation";"Butanoate metabolism";"Tryptophan metabolism";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Phenylalanine metabolism";"Lysine degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"beta-Alanine metabolism";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Androstenedione degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Limonene and pinene degradation";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Aminobenzoate degradation";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation"
XP_049887791.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049866091.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049868331.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049866621.1	29	Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559586;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-69541;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"PI3K-Akt signaling pathway";"DNA Damage/Telomere Stress Induced Senescence";"mTOR signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Stabilization of p53";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049867601.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049880717.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049884498.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi"
XP_049874388.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049876158.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12;MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
XP_049874608.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049884806.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049880965.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049871545.1	5	KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-922	"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I"
XP_049874664.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049879234.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049870884.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049871012.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_049868553.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER"
XP_049875145.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-5738	"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_049880505.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049875133.1	9	Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection"
XP_049865774.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049878559.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049865154.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049868578.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049878248.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049870583.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation"
XP_049880749.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_049885626.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049870949.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049883570.1	42	Reactome: R-HSA-2559586;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5250924;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-110331	"DNA Damage/Telomere Stress Induced Senescence";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"B-WICH complex positively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"DNA methylation";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Cleavage of the damaged purine"
XP_049875082.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869271.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049885455.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049878946.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_049867137.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690	"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events"
XP_049877879.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049884838.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049873870.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049881385.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049884477.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049879910.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049868569.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_049867478.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049882995.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236	"B-WICH complex positively regulates rRNA expression";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Meiotic synapsis";"DNA methylation";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"HATs acetylate histones";"HCMV Late Events";"PRC2 methylates histones and DNA";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049878376.1	6	KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism"
XP_049869326.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049869529.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049884876.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049886780.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_049883532.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049875142.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049866146.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_049887276.1	14	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_049865890.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049877459.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049875863.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049877331.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049876284.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049870628.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049866912.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049873179.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049870612.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049883704.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049867409.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049887557.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049876747.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_049869705.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049882910.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049865622.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049866562.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049883197.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_049886217.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049881592.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-8963901	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Chylomicron remodeling"
XP_049865066.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049876898.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049884014.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_049882127.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_049867890.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049869683.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049868970.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049876086.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049876287.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049877753.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049879761.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5	"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049876048.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049885216.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049877794.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_049868094.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049879775.1	11	MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5	"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049885120.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049873161.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_049885834.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049887184.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049878771.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049870764.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049866542.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049867354.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049878611.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049866859.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049881178.1	2	Reactome: R-HSA-211945;Reactome: R-HSA-3299685	"Phase I - Functionalization of compounds";"Detoxification of Reactive Oxygen Species"
XP_049877791.1	11	Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948	"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049876315.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049872076.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049877910.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516	"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin"
XP_049876911.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049871688.1	10	MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909	"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)"
XP_049881995.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049871544.1	5	MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_049879062.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_049872189.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049881414.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049882700.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049875386.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_049872169.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_049883495.1	57	Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684	"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Hedgehog 'on' state"
XP_049887358.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049884869.1	11	Reactome: R-HSA-167172;Reactome: R-HSA-6807878;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6811434;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"Transcription of the HIV genome";"COPI-mediated anterograde transport";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"COPI-dependent Golgi-to-ER retrograde traffic";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_049874695.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_049878664.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049882091.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049886954.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049867658.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_049881809.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049869833.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049864853.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049872839.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049880512.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049882401.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049878857.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5989	"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Fatty acid biosynthesis";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)"
XP_049883573.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049880605.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_049877713.1	52	Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-174178	"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049871299.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049868526.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049867501.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049879273.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5849;MetaCyc: PWY-5892;Reactome: R-HSA-2142789;MetaCyc: PWY-5844	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis"
XP_049884644.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049886390.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049865455.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049881661.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049872560.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049873157.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_049884971.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049883017.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049876030.1	4	KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_049872413.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049886121.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049874835.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049880563.1	10	MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_049888109.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049870287.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049865569.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_049881334.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049875276.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049878751.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049864870.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049866328.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049878546.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049879794.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049877390.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049884773.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049869714.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049886739.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation"
XP_049879243.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_049882004.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049874891.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049881764.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_049881429.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_049879628.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_049873159.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049865435.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_049882595.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049868765.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049878089.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection"
XP_049865254.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049875261.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049882071.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049882606.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049877995.1	37	Reactome: R-HSA-9639288;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-2132295;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-204005;Reactome: R-HSA-6784531;Reactome: R-HSA-983170;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214	"Amino acids regulate mTORC1";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"MHC class II antigen presentation";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"COPII-mediated vesicle transport";"tRNA processing in the nucleus";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins"
XP_049867034.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049886035.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049883703.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049874557.1	11	Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)"
XP_049888066.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049870970.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049883882.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049879233.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049871580.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049887896.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6811436	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049882463.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049885838.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049887189.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049881366.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_049869754.1	14	MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051	"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I"
XP_049887956.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049887632.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes"
XP_049874167.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049885043.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049880006.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879808.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_049865425.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148	"Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049885138.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049887964.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049874759.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887485.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049873464.1	20	KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7288;Reactome: R-HSA-9033241	"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import"
XP_049879875.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049867106.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049880272.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049886580.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049886994.1	18	MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7224	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"CMP phosphorylation";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage"
XP_049875790.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880385.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049888256.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_049866734.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049876897.1	13	MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52	"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation"
XP_049870140.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017	"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_049871964.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049882382.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_049865895.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049887423.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049877329.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049883897.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_049871967.1	4	Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-162699	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose"
XP_049879150.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049881802.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049876116.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049880616.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049875860.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049877638.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049882131.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049876456.1	29	Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_049883702.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049873817.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_049884891.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72706	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049879367.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_049881841.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway"
XP_049886003.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049872751.1	5	Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046	"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_049867136.1	24	Reactome: R-HSA-4085001;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-4341670;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00052+3.2.1.23;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00511+3.2.1.23;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-2206308;Reactome: R-HSA-6798695;MetaCyc: PWY-7790;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3	"Sialic acid metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Galactose metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Other glycan degradation";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"MPS IV - Morquio syndrome B";"Neutrophil degranulation";"UMP biosynthesis II";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049872085.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049885922.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_049880508.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049874679.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049871990.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049873067.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049876768.1	7	Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-110330	"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049874168.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049866521.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049878865.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049887582.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049875808.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049884746.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049870567.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049875331.1	9	Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER"
XP_049866625.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049883526.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049866852.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049877754.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049866368.1	12	KEGG: 00230+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-174362	"Purine metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Selenocompound metabolism";"Selenate reduction";"Transport and synthesis of PAPS"
XP_049882394.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049874117.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049884648.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049870542.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049883012.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049880589.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049866420.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7589;Reactome: R-HSA-1483166	"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_049881840.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049874645.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049875129.1	9	Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection"
XP_049887914.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049865590.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049867408.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_049866903.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049887416.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_049876582.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049873996.1	24	Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-202424;Reactome: R-HSA-165158	"FCERI mediated NF-kB activation";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"PIP3 activates AKT signaling";"RSK activation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Integrin signaling";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Downstream TCR signaling";"Activation of AKT2"
XP_049883683.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049868341.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049872736.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049883635.1	17	Reactome: R-HSA-196780;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168	"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049869501.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049875779.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049881797.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049879214.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_049876849.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_049882532.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866738.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_049877309.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions"
XP_049865902.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049875287.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_049867384.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049866702.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049881032.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049873724.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049873698.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049869277.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049885217.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049887594.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049867375.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049867851.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049884107.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049867316.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_049875470.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049883871.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049868192.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049885152.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049866167.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049873349.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049865232.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049869960.1	4	MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049867857.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049879491.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049869979.1	9	Reactome: R-HSA-8963684;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5	"Tyrosine catabolism";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism"
XP_049876961.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_049873800.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_049868412.1	18	KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115	"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Gluconeogenesis";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049888111.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049867423.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_049870394.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049871968.1	4	Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose"
XP_049879920.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049875861.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049886212.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868109.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_049873878.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049877319.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629	"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049874049.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531	"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus"
XP_049875036.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049875431.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_049877332.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049867496.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049869378.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049865648.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_049882715.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049883670.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049878507.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049881425.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049873405.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049874311.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_049874156.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049877980.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049880182.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921	"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_049882022.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049885840.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
XP_049869447.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049884921.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049879173.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049874948.1	5	KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20	"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes"
XP_049869022.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887635.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049882031.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049881252.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049879060.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049879327.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_049867417.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253	"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex"
XP_049887730.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049884732.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049864976.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049877822.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_049868434.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049879221.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049866652.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-186797	"ECM proteoglycans";"NCAM1 interactions";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Anchoring fibril formation";"Signaling by PDGF"
XP_049876464.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_049888097.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049874786.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049868356.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049887216.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049865155.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049871525.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049883624.1	6	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049874837.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049872445.1	4	KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049881632.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049869732.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049870633.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_049869276.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049886386.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049882062.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049875954.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049874515.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049865116.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049883013.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049882527.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049875805.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049865526.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049881420.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049877310.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629	"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049864942.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049869663.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049865136.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_049884698.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049884699.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049881202.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049874840.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049867863.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049874855.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049881196.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049875515.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049869298.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049884454.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049873896.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049865634.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049879240.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049881433.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049880952.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_049877320.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629	"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_049868614.1	7	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049876175.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049879339.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049882936.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049873263.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_049879945.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049873778.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880376.1	22	MetaCyc: PWY-5659;MetaCyc: PWY-5054;MetaCyc: PWY-621;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;MetaCyc: PWY-622;MetaCyc: PWY-6992;MetaCyc: PWY-5384;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-8013;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-7385;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6981;MetaCyc: PWY-5514	"GDP-mannose biosynthesis";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Starch biosynthesis";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049871162.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049867365.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_049883294.1	7	Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980	"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis"
XP_049885846.1	7	KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208	"Phenylalanine metabolism";"Phenylketonuria";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism"
XP_049883040.1	42	Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-73728;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-427389	"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"HATs acetylate histones";"HCMV Late Events";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"RNA Polymerase I Promoter Opening";"DNA methylation";"RMTs methylate histone arginines";"Meiotic synapsis";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049881603.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049868871.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049869724.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049879399.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049879409.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049878900.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_049869681.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049867093.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049876956.1	5	KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_049869163.1	17	Reactome: R-HSA-1362300;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-69202;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-69656	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"G0 and Early G1";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049875885.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049875158.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049874800.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049869830.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049873035.1	16	Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828	"Gap junction degradation";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis"
XP_049875971.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049884800.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049878446.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049882732.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049880732.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049868270.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049881003.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
XP_049879858.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049873521.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049887591.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049886163.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049883695.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049865650.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049876766.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049883644.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049883634.1	17	Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2	"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism"
XP_049875747.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
YP_010449137.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049883383.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049870106.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123	"Purine metabolism";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I"
XP_049868410.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049883458.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049871803.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049877317.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049866966.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_049872001.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049867953.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049867432.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049874276.1	33	MetaCyc: PWY-5751;MetaCyc: PWY-6333;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5057;KEGG: 00626+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-6871;MetaCyc: PWY-5082;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00010+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-7111;MetaCyc: PWY-6342;Reactome: R-HSA-71384;MetaCyc: PWY-6313;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-7396;MetaCyc: PWY-7013;MetaCyc: PWY-5480;MetaCyc: PWY-6802;KEGG: 00260+1.1.1.1;KEGG: 00980+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5078;MetaCyc: PWY-5076	"Phenylethanol biosynthesis";"Acetaldehyde biosynthesis I";"Chitin degradation to ethanol";"Retinol metabolism";"Drug metabolism - cytochrome P450";"Protein S-nitrosylation and denitrosylation";"L-valine degradation II";"Naphthalene degradation";"Formaldehyde oxidation II (glutathione-dependent)";"3-methylbutanol biosynthesis (engineered)";"L-methionine degradation III";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol II";"Glycolysis / Gluconeogenesis";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Pyruvate fermentation to ethanol III";"Pyruvate fermentation to isobutanol (engineered)";"Noradrenaline and adrenaline degradation";"Ethanol oxidation";"Serotonin degradation";"Tyrosine metabolism";"L-phenylalanine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol I";"Salidroside biosynthesis";"Glycine, serine and threonine metabolism";"Metabolism of xenobiotics by cytochrome P450";"alpha-Linolenic acid metabolism";"Methane metabolism";"L-isoleucine degradation II";"L-leucine degradation III"
XP_049874217.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049881388.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11	"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway"
XP_049886064.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_049870978.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049879620.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049882628.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
YP_010449125.1	7	Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-6692;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-3781	"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)"
XP_049877351.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049879754.1	11	KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)"
XP_049876807.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049869735.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003	"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol"
XP_049875921.1	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
XP_049879664.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867993.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049874320.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049881345.1	5	Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532	"Pyrimidine catabolism";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)"
XP_049875969.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049875568.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_049868342.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049873763.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049884890.1	12	Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-450408	"mTORC1-mediated signalling";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_049875148.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049869584.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049885170.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_049870080.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049878024.1	7	KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation"
XP_049886165.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_049870395.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049866149.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint"
XP_049874087.1	29	Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779	"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049874581.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049867868.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_049865888.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049882511.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049868866.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049866693.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049879757.1	11	MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5	"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049880546.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049874085.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-113418	"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex"
XP_049873665.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049875277.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_049874249.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049874959.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424	"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Orc1 removal from chromatin";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling"
XP_049866423.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049873836.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049876741.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049866709.1	12	Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049868524.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049868739.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049865681.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_049874086.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2022928	"HS-GAG degradation";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG biosynthesis"
XP_049876169.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049868476.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_049871541.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049871316.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_049883843.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049877445.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049870377.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049885659.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049886283.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049866078.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_049866558.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049879183.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049888108.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_049881657.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049883288.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049880786.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049878228.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049883934.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049886391.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049873805.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_049881948.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_049867952.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049869876.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049870957.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_049875282.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_049881270.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049879902.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049867535.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049870008.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049874379.1	31	Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWYG-321	"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";""
XP_049874166.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864943.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049887585.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049883836.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049883628.1	17	MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381	"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_049879265.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049881699.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049887934.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049866277.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685	"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species"
XP_049874472.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_049864850.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049874474.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_049878049.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049878281.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination"
XP_049880111.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import"
XP_049886214.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049866959.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_049885518.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049884663.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049867252.1	11	KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381	"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)"
XP_049882005.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049864920.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049870977.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049870147.1	13	KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690	"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)"
XP_049869940.1	7	Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210	"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_049875976.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049873769.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049884103.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049880257.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_049867648.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_049876979.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_049886374.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049868637.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049872054.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049878015.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049878495.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_049867453.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7854;MetaCyc: PWY-7606	"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_049887922.1	3	Reactome: R-HSA-202433;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049865555.1	19	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-3214858;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-8876725;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"RMTs methylate histone arginines";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Protein methylation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049866732.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049875034.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049882470.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_049876502.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049873995.1	24	Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-2871837;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-5674400;Reactome: R-HSA-389357	"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"FCERI mediated NF-kB activation";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"RSK activation";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Integrin signaling";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Downstream TCR signaling";"Activation of AKT2";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling"
XP_049875255.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049882686.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049885995.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049872609.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049866639.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-6804757;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559586;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-349425;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-6804760;Reactome: R-HSA-6796648	"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Regulation of TP53 Degradation";"Relaxin signaling pathway";"DNA Damage/Telomere Stress Induced Senescence";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"mTOR signaling pathway";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Human papillomavirus infection";"Stabilization of p53";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Thermogenesis";"HDR through Homologous Recombination (HRR)";"Autodegradation of the E3 ubiquitin ligase COP1";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049877715.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_049873534.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_049878948.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination"
XP_049871190.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_049876061.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_049872216.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049866370.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049879120.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049867179.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049868740.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049867301.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_049869191.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049872037.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049874061.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049880813.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_049870472.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated"
XP_049878100.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049865113.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-918233;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568	"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Attenuation phase"
XP_049883296.1	7	Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2	"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling";"Photosynthesis"
XP_049881820.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049867004.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869489.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049870005.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049883586.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049876923.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049883474.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049880055.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049877079.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049876082.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049865544.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695	"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation"
XP_049881267.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_049871464.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049883553.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049873999.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_049872200.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049868332.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049877730.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049881205.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049869882.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_049867889.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049881295.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049869781.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049883870.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049874269.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049868589.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049882605.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049866366.1	12	Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;MetaCyc: PWY-5340	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Purine metabolism";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfate activation for sulfonation"
XP_049869140.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_049882174.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049879766.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5	"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_049883806.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049875549.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049868144.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883386.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_049867870.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_049872017.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049887353.1	13	MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5	"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism"
XP_049874653.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_049874787.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049871344.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049882566.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049886159.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049865150.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049880736.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049869306.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049874518.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049880249.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049884432.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_049885947.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049873782.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_049876285.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049879229.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049887709.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049871024.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-212300	"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA"
XP_049869472.1	6	KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020	"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Mitochondrial protein import"
XP_049877880.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867464.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049866288.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049867400.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049870661.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049885642.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049886944.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049883841.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049873416.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574	"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II"
XP_049875957.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049869959.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049872208.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049865404.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049874841.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049878538.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049866947.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049882632.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049880496.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049869211.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049873171.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_049878282.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_049886410.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049868983.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex"
XP_049870146.1	13	KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)"
XP_049879212.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049872427.1	10	Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_049875514.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049881180.1	2	Reactome: R-HSA-211945;Reactome: R-HSA-3299685	"Phase I - Functionalization of compounds";"Detoxification of Reactive Oxygen Species"
XP_049870956.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_049869005.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360	"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049865242.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049873378.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_049877764.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049876607.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049865044.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876170.1	42	KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7094;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00360+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-7654;MetaCyc: PWY-5138;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-7778;KEGG: 00640+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863	"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid elongation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid salvage";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Phenylalanine metabolism";"Lysine degradation";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl tert-butyl ether degradation";"Benzoate degradation";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Propanoate metabolism";"Tryptophan metabolism";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Fatty acid degradation";"Aminobenzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)"
XP_049872625.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049881996.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049883174.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049874684.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877050.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_049872317.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049869247.1	14	Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167238	"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_049867403.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049883858.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_049873439.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6	"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism"
XP_049886862.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049883928.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049884523.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-8849932	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules"
XP_049873069.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049865791.1	3	Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049869673.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_049868883.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867383.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049866785.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049865268.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049872127.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049876042.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049884767.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_049867361.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049871014.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049873553.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049872225.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049866735.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883129.1	6	MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22	"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism"
XP_049881272.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049881794.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_049879584.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049878954.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049884212.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"Separation of Sister Chromatids";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin"
XP_049874162.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049865012.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049872996.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884929.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049872570.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_049867391.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049870339.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049879005.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049869192.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049883270.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020	"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import"
XP_049869679.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049865896.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880050.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049865339.1	3	Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100	"Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis"
XP_049883924.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy"
XP_049867763.1	14	KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-5497;KEGG: 00983+1.17.3.2;MetaCyc: PWY-6538;KEGG: 00232+1.17.3.2;Reactome: R-HSA-74259;MetaCyc: PWY-5695;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6999	"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Drug metabolism - other enzymes";"Caffeine degradation III (bacteria, via demethylation)";"Caffeine metabolism";"Purine catabolism";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation"
XP_049864984.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049879938.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049885810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866229.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049867039.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049872024.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049868860.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049885117.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049888237.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049873917.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049878170.1	4	KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049871534.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049884443.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049871495.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049885991.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049883349.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_049868997.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880	"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases"
XP_049865390.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049876017.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_049864878.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049868040.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049869590.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049870500.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_049879164.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049881778.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049876465.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049879480.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049885610.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049879479.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049888179.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-193681;Reactome: R-HSA-5626978	"Glycosphingolipid metabolism";"Ceramide signalling";"TNFR1-mediated ceramide production"
XP_049882476.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049870878.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049883272.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049867970.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_049867655.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049882109.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049882473.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049867874.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874613.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049864851.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049870111.1	5	Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049877693.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049873663.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049875262.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049884386.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049874666.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049883372.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_049866960.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049864903.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049877750.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049876641.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_049865885.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049885173.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049885206.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049868946.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-2559582	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)"
XP_049875191.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049884991.1	5	MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168	"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)"
XP_049880602.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049878022.1	7	KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049873201.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049877430.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049885538.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049880416.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049869274.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049868529.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049877447.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049871589.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049865551.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation"
XP_049870754.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049882853.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity"
XP_049867087.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate"
XP_049879780.1	11	KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049880326.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049873326.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_049884880.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049882176.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_049878783.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling"
XP_049868678.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049883616.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049878740.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049869704.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049865118.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049884766.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049873314.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049879326.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049879921.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049885022.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049866728.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049868671.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049872086.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049873160.1	10	MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842	"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II"
XP_049867033.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049871017.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880250.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_049869153.1	17	Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-2559585;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-139915;Reactome: R-HSA-113501;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1362300;Reactome: R-HSA-9616222	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"Oncogene Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Activation of PUMA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional regulation of granulopoiesis"
XP_049878039.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049879777.1	11	KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II"
XP_049884815.1	6	MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
XP_049875977.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049875281.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049880869.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_049883531.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049872492.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
YP_010449132.1	7	MetaCyc: PWY-6692;MetaCyc: PWY-5083;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-3781	"Fe(II) oxidation";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)"
XP_049867513.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049867353.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049885962.1	19	Reactome: R-HSA-114604;Reactome: R-HSA-5663220;Reactome: R-HSA-428543;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-525793	"GPVI-mediated activation cascade";"RHO GTPases Activate Formins";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"Rho GTPase cycle";"RHO GTPases activate PAKs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"Myogenesis"
XP_049885290.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097	"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway"
XP_049880966.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049877653.1	5	Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-901032	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)"
XP_049876798.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049866741.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling"
XP_049872834.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049874214.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049880275.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049866944.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049880408.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_049882909.1	5	MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614	"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate biosynthesis";"Tetrahydrofolate biosynthesis"
XP_049875280.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins"
XP_049884273.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049868101.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049883152.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049882196.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049869246.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_049887402.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049879223.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049876609.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049873406.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049874172.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690	"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events"
XP_049877493.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049884664.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049887245.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049864952.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049879511.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis"
XP_049883857.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049872493.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_049876188.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-8862803	"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_049875468.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport"
XP_049881966.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049866905.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049882269.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_049866949.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049873273.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049866923.1	5	Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_049881288.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049872021.1	34	Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823	"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex"
XP_049886324.1	10	Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-5628897	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Macroautophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes"
XP_049873559.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049877262.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049876251.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049884984.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049871620.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049880587.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049887839.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049885564.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049865214.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049871496.1	11	MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_049880570.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049869011.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049865573.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049887638.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049880555.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049885619.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865911.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_049884642.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049877484.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_049871424.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877431.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049878945.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049879976.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049864946.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049868519.1	13	MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049869007.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Ub-specific processing proteases"
XP_049869542.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049878244.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049871010.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049878843.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049868186.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883142.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049887198.1	16	KEGG: 00020+6.2.1.4;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)"
XP_049877444.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049877077.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049881801.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_049866214.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861	"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly"
XP_049871604.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049885258.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049865341.1	5	Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-165159	"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"mTOR signalling"
XP_049873935.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049864936.1	6	Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_049873545.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-69473	"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint"
XP_049868641.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049881994.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049877938.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144	"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_049872188.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049868277.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049885820.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049869490.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049868185.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049868115.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_049883271.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049875201.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049877405.1	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026	"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)"
XP_049875946.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_049867233.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049874044.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049881173.1	4	MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_049885298.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-193648	"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK"
XP_049878739.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049868280.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049877970.1	3	Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25	"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"Other glycan degradation"
XP_049870026.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049873414.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049887434.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2"
XP_049867546.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049871450.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049879716.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049882528.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049871384.1	30	Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-2564830;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript"
XP_049883385.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049884723.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049886022.1	29	Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER"
XP_049872506.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889	"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes"
XP_049873820.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049877401.1	4	KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol"
XP_049875717.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049877357.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_049881693.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049870973.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049878812.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049867705.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049873222.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049878113.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_049874224.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049874764.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049879230.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049881562.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-381426	"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"VLDL assembly";"Chylomicron remodeling";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Chylomicron assembly";"Chylomicron clearance";"Clathrin-mediated endocytosis";"VLDL clearance";"LDL remodeling";"Retinoid metabolism and transport";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049877751.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049879566.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049876664.1	2	Reactome: R-HSA-177135;Reactome: R-HSA-177128	"Conjugation of benzoate with glycine";"Conjugation of salicylate with glycine"
XP_049865797.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_049866314.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_049877234.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168	"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049872857.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049886304.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_049877819.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049883200.1	18	KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Neutrophil degranulation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_049885425.1	3	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation"
XP_049868298.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_049872301.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049881777.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049882080.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049875919.1	20	Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;KEGG: 04926+2.7.11.1	"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Human immunodeficiency virus 1 infection";"Thermogenesis";"HSF1-dependent transactivation";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"mTOR signalling";"Relaxin signaling pathway"
XP_049866534.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049868212.1	7	KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-5265;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_049868639.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049872868.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241	"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import"
XP_049867545.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049867135.1	11	KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154	"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049869287.1	14	MetaCyc: PWY-2161;MetaCyc: PWY-1622;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-181;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1	"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Folate transformations II (plants)";"Photorespiration ";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"One carbon pool by folate";"Glycine betaine degradation I";"Methane metabolism"
XP_049874612.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049882356.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049878943.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049879769.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049879236.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049886397.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049872000.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049870539.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049884385.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049883827.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049872735.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049884447.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876912.1	13	KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation"
XP_049866159.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049875092.1	16	Reactome: R-HSA-3214847;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565	"HATs acetylate histones";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049875272.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Insulin receptor recycling";"ATP biosynthesis";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_049871309.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049869751.1	26	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events"
XP_049885179.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling"
XP_049877312.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049885978.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049886017.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_049885132.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049869684.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049866690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049868551.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400	"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER"
XP_049885889.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049868211.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174411	"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere"
XP_049873158.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_049879457.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049875112.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049884301.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049882287.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_049870097.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049866647.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_049875693.1	7	Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12	"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism"
XP_049878213.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049882096.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049867343.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19	"beta-Alanine metabolism";"4-aminobutanoate degradation III";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"Propanoate metabolism"
XP_049878247.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_049883701.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049879013.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049869297.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880970.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_049886175.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049868600.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049870088.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049868624.1	179	Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-5689877;Reactome: R-HSA-3134975;Reactome: R-HSA-2979096;Reactome: R-HSA-1169408;Reactome: R-HSA-1358803;Reactome: R-HSA-6781823;Reactome: R-HSA-936964;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2672351;Reactome: R-HSA-174490;Reactome: R-HSA-9014325;Reactome: R-HSA-1236382;Reactome: R-HSA-168638;Reactome: R-HSA-201681;Reactome: R-HSA-6791226;Reactome: R-HSA-5675482;Reactome: R-HSA-5362768;Reactome: R-HSA-9636383;Reactome: R-HSA-1799339;Reactome: R-HSA-6782135;Reactome: R-HSA-5689901;Reactome: R-HSA-2894862;Reactome: R-HSA-8866654;Reactome: R-HSA-901032;Reactome: R-HSA-5675221;Reactome: R-HSA-72764;Reactome: R-HSA-5654726;Reactome: R-HSA-5610783;Reactome: R-HSA-8876493;Reactome: R-HSA-6781827;Reactome: R-HSA-72689;Reactome: R-HSA-5357905;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5693607;Reactome: R-HSA-8941858;Reactome: R-HSA-2691232;Reactome: R-HSA-9637628;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-2173795;Reactome: R-HSA-1236974;Reactome: R-HSA-975957;Reactome: R-HSA-1169091;Reactome: R-HSA-977225;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-6782210;Reactome: R-HSA-69541;Reactome: R-HSA-5696395;Reactome: R-HSA-180585;Reactome: R-HSA-6807004;Reactome: R-HSA-5668541;Reactome: R-HSA-5656169;Reactome: R-HSA-9615710;Reactome: R-HSA-5607764;Reactome: R-HSA-2173796;Reactome: R-HSA-8863795;Reactome: R-HSA-2408557;Reactome: R-HSA-5658442;Reactome: R-HSA-8856828;Reactome: R-HSA-937042;Reactome: R-HSA-9013973;Reactome: R-HSA-3322077;Reactome: R-HSA-6804760;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-5685942;Reactome: R-HSA-3785653;Reactome: R-HSA-209560;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-110312;Reactome: R-HSA-174184;Reactome: R-HSA-8849469;Reactome: R-HSA-975144;Reactome: R-HSA-69231;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-4641263;Reactome: R-HSA-175474;Reactome: R-HSA-912631;Reactome: R-HSA-211733;Reactome: R-HSA-975110;Reactome: R-HSA-1295596;Reactome: R-HSA-445989;Reactome: R-HSA-8951664;Reactome: R-HSA-162588;Reactome: R-HSA-2122948;Reactome: R-HSA-2467813;Reactome: R-HSA-205043;Reactome: R-HSA-8856825;Reactome: R-HSA-5654733;Reactome: R-HSA-192823;Reactome: R-HSA-450302;Reactome: R-HSA-182971;Reactome: R-HSA-5689896;Reactome: R-HSA-2173788;Reactome: R-HSA-975163;Reactome: R-HSA-69481;Reactome: R-HSA-174048;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;Reactome: R-HSA-6783310;Reactome: R-HSA-9633012;Reactome: R-HSA-917729;Reactome: R-HSA-156827;Reactome: R-HSA-9033241;Reactome: R-HSA-2559580;Reactome: R-HSA-8875360;Reactome: R-HSA-2559582;Reactome: R-HSA-156902;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-2559585;Reactome: R-HSA-5696397;Reactome: R-HSA-2644606;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-5684264;Reactome: R-HSA-5696394;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-382556;Reactome: R-HSA-937039;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-72706;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-179409;Reactome: R-HSA-9010553;Reactome: R-HSA-5696400;Reactome: R-HSA-5654732;Reactome: R-HSA-937041;Reactome: R-HSA-5654727;Reactome: R-HSA-9613829;Reactome: R-HSA-68827;Reactome: R-HSA-5656121;Reactome: R-HSA-4641258;Reactome: R-HSA-5693565;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-2122947;Reactome: R-HSA-450321;Reactome: R-HSA-936440;Reactome: R-HSA-202424;Reactome: R-HSA-975956;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8948747;Reactome: R-HSA-209543;Reactome: R-HSA-4608870;Reactome: R-HSA-400253;Reactome: R-HSA-69017;Reactome: R-HSA-1253288;Reactome: R-HSA-9020702;Reactome: R-HSA-110314;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8866652;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-5205685;Reactome: R-HSA-532668	"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Josephin domain DUBs";"Regulation of innate immune responses to cytosolic DNA";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"ISG15 antiviral mechanism";"Downregulation of ERBB2:ERBB3 signaling";"Formation of TC-NER Pre-Incision Complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Stimuli-sensing channels";"Membrane binding and targetting of GAG proteins";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NOD1/2 Signaling Pathway";"TCF dependent signaling in response to WNT";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of necroptotic cell death";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Prevention of phagosomal-lysosomal fusion";"SRP-dependent cotranslational protein targeting to membrane";"Dual incision in TC-NER";"Metalloprotease DUBs";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"ER Quality Control Compartment (ERQC)";"Negative regulation of MAPK pathway";"Eukaryotic Translation Termination";"Negative regulation of FGFR1 signaling";"Degradation of GLI2 by the proteasome";"InlA-mediated entry of Listeria monocytogenes into host cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of a pool of free 40S subunits";"Regulation of TNFR1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Processing of DNA double-strand break ends";"Regulation of RUNX3 expression and activity";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Modulation by Mtb of host immune system";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"ER-Phagosome pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of NF-kappaB in B cells";"Amyloid fiber formation";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Stabilization of p53";"Formation of Incision Complex in GG-NER";"Vif-mediated degradation of APOBEC3G";"Negative regulation of MET activity";"TNFR2 non-canonical NF-kB pathway";"Termination of translesion DNA synthesis";"Late endosomal microautophagy";"CLEC7A (Dectin-1) signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Downregulation of ERBB2 signaling";"Selenocysteine synthesis";"Regulation of RAS by GAPs";"Clathrin-mediated endocytosis";"IRAK2 mediated activation of TAK1 complex";"TICAM1-dependent activation of IRF3/IRF7";"Glycogen synthesis";"Regulation of TP53 Activity through Methylation";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"HDR through Homologous Recombination (HRR)";"Myoclonic epilepsy of Lafora";"NF-kB is activated and signals survival";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Translesion synthesis by REV1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Cyclin D associated events in G1";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of FZD by ubiquitination";"Assembly Of The HIV Virion";"Regulation of signaling by CBL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Spry regulation of FGF signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Neddylation";"Budding and maturation of HIV virion";"Activated NOTCH1 Transmits Signal to the Nucleus";"Separation of Sister Chromatids";"NRIF signals cell death from the nucleus";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR4 signaling";"Viral mRNA Translation";"activated TAK1 mediates p38 MAPK activation";"EGFR downregulation";"Ovarian tumor domain proteases";"Downregulation of TGF-beta receptor signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Cyclin B";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Fanconi Anemia Pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Endosomal Sorting Complex Required For Transport (ESCRT)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peroxisomal protein import";"Oxidative Stress Induced Senescence";"InlB-mediated entry of Listeria monocytogenes into host cell";"Senescence-Associated Secretory Phenotype (SASP)";"Peptide chain elongation";"Translesion Synthesis by POLH";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Oncogene Induced Senescence";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"DNA Damage Recognition in GG-NER";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"ABC-family proteins mediated transport";"IRAK1 recruits IKK complex";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of expression of SLITs and ROBOs";"Dual Incision in GG-NER";"Negative regulation of FGFR3 signaling";"IKK complex recruitment mediated by RIP1";"Negative regulation of FGFR2 signaling";"Chaperone Mediated Autophagy";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLI";"Degradation of DVL";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"NOTCH1 Intracellular Domain Regulates Transcription";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Negative regulators of DDX58/IFIH1 signaling";"Downstream TCR signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN localization";"p75NTR recruits signalling complexes";"Asymmetric localization of PCP proteins";"Circadian Clock";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB4 signaling";"Interleukin-1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Pink/Parkin Mediated Mitophagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049866901.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049869113.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_049884532.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions"
XP_049869961.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6	"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049867991.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049873417.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049878845.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881084.1	33	Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823	"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex"
XP_049871690.1	10	MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)"
XP_049876647.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049868605.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049886394.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049879713.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049865781.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II"
XP_049870872.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049872084.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049869432.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049885536.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049871050.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling"
XP_049887710.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049869494.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049885130.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049879579.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049873119.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916	"Neutrophil degranulation";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation"
XP_049866397.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049879974.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049869262.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049871554.1	14	Reactome: R-HSA-72689;Reactome: R-HSA-2022377;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Metabolism of Angiotensinogen to Angiotensins";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049882072.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049879484.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049881028.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_049880128.1	10	KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370	"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism"
XP_049885177.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049881779.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049884875.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049882073.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049884444.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049879979.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049881135.1	10	KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-977225;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691	"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I"
XP_049880290.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049866880.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049883825.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049867582.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749	"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs"
XP_049871770.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880175.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_049865638.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049886049.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049879648.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049866531.1	11	KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9614657	"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"FOXO-mediated transcription of cell death genes"
XP_049869632.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049880828.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_049869651.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER"
XP_049871584.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_049869827.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049876693.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049874165.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049866710.1	10	KEGG: 04070+2.7.1.153;Reactome: R-HSA-9027276;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153	"Phosphatidylinositol signaling system";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049865633.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049865810.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049875852.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049887554.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049875294.1	14	MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II"
XP_049885409.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049880409.1	14	KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PE";"Anandamide biosynthesis I"
XP_049877700.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_049873393.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049871486.1	22	MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-7724;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-5353	"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)"
XP_049883374.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_049865904.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049868818.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138	"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_049888098.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049869009.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_049868852.1	10	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"HATs acetylate histones";"Ub-specific processing proteases";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049872325.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876576.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_049879526.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36	"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
XP_049873150.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049885251.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881315.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049888099.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049873556.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049867805.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049874620.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049884740.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049866856.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049881456.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_049885616.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049868752.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049885856.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_049878441.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049882973.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049864854.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049886075.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_049887486.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049879731.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049879239.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049868597.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049871377.1	27	Reactome: R-HSA-113418;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72203;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-167242;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-9010553;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-159231;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-159236;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-77588;Reactome: R-HSA-167158;Reactome: R-HSA-111367;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-6803529	"Formation of the Early Elongation Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"FGFR2 alternative splicing"
XP_049870762.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049880745.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049873716.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049882756.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049885547.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049871051.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_049876466.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_049876564.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049883377.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881816.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049879251.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049878503.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_049883375.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5872;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-6708	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_049872425.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464	"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins"
XP_049873269.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049876494.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049867925.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049869157.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049870434.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049871122.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049882723.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049875710.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689	"tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I"
XP_049875814.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049877836.1	13	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis"
XP_049867635.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049875862.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_049865243.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049868602.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049865832.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_049866177.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049878411.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049877051.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049879177.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569	"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049869553.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049882642.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049870150.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049883784.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_049879679.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049879772.1	11	KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049879322.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049875271.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Ion channel transport"
XP_049885618.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873038.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049871438.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049875099.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)"
XP_049873396.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606	"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_049877227.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_049870544.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497	"ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049886174.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049867607.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049881800.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_049874215.1	4	Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I"
XP_049885685.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_049865893.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049871705.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049882157.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049870465.1	31	MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-5142;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220	"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Biotin metabolism";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_049886243.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049875143.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_049885047.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6	"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism"
XP_049884471.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873645.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049882499.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049886541.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049869188.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883872.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049864909.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_049867656.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_049870951.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049884855.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049873454.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7007	"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)"
XP_049866724.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_049877640.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049888246.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049870252.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049880576.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049867833.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049884419.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049871455.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049869003.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971	"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation"
XP_049867457.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049885178.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_049877330.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049875288.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049869319.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049873939.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049879434.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049880173.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049864865.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049874451.1	2	KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5	"Fructose and mannose metabolism";"Pentose and glucuronate interconversions"
XP_049881253.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867965.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-381426;Reactome: R-HSA-2173796	"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_049881812.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049880174.1	7	KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539	"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism"
XP_049865990.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_049878454.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049867029.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049869698.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_049865835.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049870555.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049885175.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049874387.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049877229.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_049877350.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049878545.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049869014.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887505.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049884769.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049875526.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049869269.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049870631.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049883042.1	42	Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-2559580;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5625886;Reactome: R-HSA-5693565;Reactome: R-HSA-110330	"HATs acetylate histones";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Oxidative Stress Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"RMTs methylate histone arginines";"DNA methylation";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_049880320.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049873233.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis"
XP_049875900.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049877233.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049865413.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049867281.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049877315.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171	"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions"
XP_049884448.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049866887.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049873274.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049884013.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049881369.1	7	Reactome: R-HSA-71336;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-5514;MetaCyc: PWY-6855	"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)"
XP_049873247.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_049887308.1	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_049875826.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049865231.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874760.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049888243.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866080.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400	"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER"
XP_049876782.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049868894.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_049887711.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling"
XP_049878263.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_049870761.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-3881;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8	"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049870946.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049866411.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_049880239.1	16	Reactome: R-HSA-167238;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation"
XP_049875809.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049881975.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049865393.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049873653.1	13	Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_049871989.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-5628897	"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes"
XP_049869013.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049875256.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_049877857.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049875147.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_049878434.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049880213.1	6	MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686	"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I"
XP_049867481.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049882129.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition"
XP_049869018.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049872283.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049865055.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874827.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049869135.1	17	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-69202;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-1362300;Reactome: R-HSA-111448;Reactome: R-HSA-2559580;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-6804114;Reactome: R-HSA-2559585	"G1/S-Specific Transcription";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin E associated events during G1/S transition";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of NOXA and translocation to mitochondria";"Oxidative Stress Induced Senescence";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oncogene Induced Senescence"
XP_049868633.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049873403.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6	"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism"
XP_049865456.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049867433.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049866557.1	16	Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-179409	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A"
XP_049879534.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049878199.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-6823;MetaCyc: PWY-7887	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_049868577.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049872831.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_049877389.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_049869300.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049881390.1	10	MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism"
XP_049869286.1	14	MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2161;MetaCyc: PWY-1622;Reactome: R-HSA-196757;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1	"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"One carbon pool by folate";"Methane metabolism";"Glycine betaine degradation I";"Folate polyglutamylation";"Formaldehyde assimilation I (serine pathway)";"Metabolism of folate and pterines";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations II (plants)";"Folate transformations I";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism"
XP_049880770.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049864887.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049868971.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049872628.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049882900.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_049871562.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049869124.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702	"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling"
XP_049881808.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049879411.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868992.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049866178.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049883682.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049877830.1	12	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049882735.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_049876491.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049870004.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049881770.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049869239.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"MAP2K and MAPK activation";"mTORC1-mediated signalling";"mTOR signalling";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_049887246.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049885989.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049882630.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049882500.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049885511.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049878059.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049867378.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049877392.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049879536.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049869717.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049866334.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049870439.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation"
XP_049888137.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049883500.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049875109.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049877385.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049865487.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049887459.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_049879751.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049867118.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049869289.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049871621.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049884711.1	11	Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling"
XP_049876214.1	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
XP_049886948.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866874.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-3238698	"Neutrophil degranulation";"WNT ligand biogenesis and trafficking"
XP_049867390.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049877052.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_049869707.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_049887359.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049887352.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5	"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes"
XP_049880527.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049886006.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049880706.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_049877796.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_049880542.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049886754.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049872610.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049866953.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049885613.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882683.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049875782.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049868131.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049881659.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049871492.1	7	Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_049872551.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_049876959.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_049885108.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049873487.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_049876579.1	9	Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex"
XP_049887435.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation"
XP_049867038.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049865778.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049879478.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_049877292.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049865937.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049868486.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887208.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism"
XP_049884193.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis"
XP_049878017.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049884784.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_049884870.1	11	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807878;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-6811434;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"COPI-mediated anterograde transport";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"COPI-dependent Golgi-to-ER retrograde traffic";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049878754.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049873886.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049887787.1	4	KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_049867950.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877696.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_049880893.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049875097.1	16	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-3214847	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"HATs acetylate histones"
XP_049867398.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049866768.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049872913.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Gap junction assembly";"Cilium Assembly";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events"
XP_049872533.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049866871.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049877574.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049877421.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049883498.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049869314.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"TP53 Regulates Metabolic Genes";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049879219.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049881379.1	10	MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis"
XP_049868046.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_049883731.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049868673.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_049876277.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_049866316.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
YP_010449129.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049883785.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_049884968.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049879249.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049885647.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049868850.1	8	MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049879756.1	11	MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5	"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049882267.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049872535.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_049870258.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049877591.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049882270.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049880034.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467	"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs"
XP_049867387.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049873720.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049868876.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049873888.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049887432.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049874765.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_049881998.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049881935.1	52	Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-5250924;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-5617472;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-8851708	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"B-WICH complex positively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Signaling by FGFR2 IIIa TM"
XP_049877328.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049868570.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_049883758.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_049883740.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880494.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049880151.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_049870095.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049882971.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049869318.1	6	Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-2173788	"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling"
XP_049871288.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_049873441.1	6	Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049886941.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049882411.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049887967.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049884111.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049884045.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_049867401.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049881999.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049870590.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167243	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Tat-mediated HIV elongation arrest and recovery"
XP_049867364.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_049868808.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049865387.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_049887864.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68952	"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"DNA replication initiation"
XP_049874160.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049887417.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_049870050.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_049874687.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049873148.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049882092.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049869055.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049865361.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_049882521.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049874961.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_049886211.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866076.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049872856.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049872087.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049876104.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049887030.1	14	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049880528.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049876183.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049867815.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049877805.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049869736.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003	"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol"
XP_049869804.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_049884964.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis"
XP_049880815.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049871127.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049874567.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049875283.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049872433.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049875983.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049880411.1	10	MetaCyc: PWY-7979;Reactome: R-HSA-162699;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_049885180.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049870224.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_049879465.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_049886207.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049871977.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049878504.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424	"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"ER-Phagosome pathway";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling"
XP_049873240.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049884807.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049871035.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_049881698.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049882574.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049867396.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887537.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049869200.1	8	MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis"
XP_049864886.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049878612.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049883548.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049870889.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049884829.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049879407.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049865059.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_049868893.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049880928.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049884762.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049872410.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049870839.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049865651.1	10	Reactome: R-HSA-5696394;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-3108214;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-5696395;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"DNA Damage Recognition in GG-NER";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"SUMOylation of DNA damage response and repair proteins";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Formation of Incision Complex in GG-NER";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_049877259.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_049869462.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049878663.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049877226.1	24	Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-420092	"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors"
XP_049883317.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902	"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049883910.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_049869258.1	25	Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-381771;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-392851	"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"Ca2+ pathway";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor"
XP_049880136.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180910	"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs"
XP_049885669.1	7	Reactome: R-HSA-1660499;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352	"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis"
XP_049881463.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049876037.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049869257.1	25	Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-381771;Reactome: R-HSA-418592;Reactome: R-HSA-8964616	"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42"
XP_049876254.1	18	MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS"
XP_049878288.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049878249.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049879712.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049867124.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049873970.1	13	KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18	"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450"
XP_049874176.1	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
XP_049871785.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049874389.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049885112.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887170.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049887428.1	9	Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-113501	"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049876115.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049866800.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_049874014.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049886987.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049876581.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_049874635.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887404.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049878694.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5578749	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs"
XP_049882608.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049883151.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049884764.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049870471.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_049880709.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049880657.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_049865929.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_049883830.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_049864997.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049873672.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049881296.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049874890.1	30	Reactome: R-HSA-8948751;Reactome: R-HSA-111447;Reactome: R-HSA-6804759;Reactome: R-HSA-6804758;Reactome: R-HSA-8876198;Reactome: R-HSA-389357;Reactome: R-HSA-1358803;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-211163;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69202;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-198693;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-389513;Reactome: R-HSA-69656;Reactome: R-HSA-199418;Reactome: R-HSA-6804757;Reactome: R-HSA-9614399;Reactome: R-HSA-9634638;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8941332	"Regulation of PTEN stability and activity";"Activation of BAD and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of TP53 Activity through Acetylation";"RAB GEFs exchange GTP for GDP on RABs";"CD28 dependent PI3K/Akt signaling";"Downregulation of ERBB2:ERBB3 signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"VEGFR2 mediated vascular permeability";"AKT-mediated inactivation of FOXO1A";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Cyclin E associated events during G1/S transition";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"AKT phosphorylates targets in the nucleus";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"CTLA4 inhibitory signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Degradation";"Regulation of localization of FOXO transcription factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Relaxin signaling pathway";"RUNX2 regulates genes involved in cell migration"
XP_049887590.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049869519.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049879601.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049878911.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049865635.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049879741.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049881467.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880274.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049874052.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-180910	"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs"
XP_049866391.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049866844.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049870161.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049872627.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049865909.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049885653.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049878534.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049875113.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049874768.1	1	Reactome: R-HSA-1614603	"Cysteine formation from homocysteine"
XP_049884243.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_049865806.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049870589.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049875796.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049881204.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049880812.1	5	MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)"
XP_049869431.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)"
XP_049879692.1	6	Reactome: R-HSA-6787450;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA modification in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_049873821.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049868527.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049883393.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5872	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049874007.1	17	MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644;MetaCyc: PWY-5532;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1	"Salinosporamide A biosynthesis";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine catabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II"
XP_049882478.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049871947.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049883293.1	7	Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation"
XP_049876129.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_049878977.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_049865936.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_049873938.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049879758.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_049869773.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049870971.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049873764.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049880503.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049869726.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049876027.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_049876865.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_049878136.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049885134.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049871623.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049871023.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049876656.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049871915.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049876135.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_049878004.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049866867.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049883571.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_049866315.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049877808.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_049882554.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049884270.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049884019.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049876861.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049884297.1	6	Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12	"Galactose catabolism";"Defective GALT can cause Galactosemia";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_049871145.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_049877057.1	57	Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858	"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity"
XP_049873838.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049883818.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049874264.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049866141.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049871946.1	4	KEGG: 00380+3.7.1.3;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-5651	"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_049875715.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049879793.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049881586.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049879683.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884734.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049871952.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_049885977.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049881932.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049878711.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049872460.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049872009.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049874632.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_049883631.1	17	Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168	"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Propanoate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_049883557.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049884279.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_049874857.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049872481.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_049865345.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049881658.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049864869.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049887190.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049882498.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049869706.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049868965.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049873223.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049882542.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-427413	"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression"
XP_049882626.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049872970.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049869523.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049877510.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049878755.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049875955.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049875543.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049879744.1	11	KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2	"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049868643.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049873866.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049881922.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049884834.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049870009.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049871146.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049873425.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291	"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)"
XP_049866306.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049870132.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_049882893.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049874067.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-381676	"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_049872500.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049867064.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049876070.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049872483.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_049873014.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879019.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049873209.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049881056.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049866398.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049875114.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049885808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049872377.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049871872.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049875402.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049868886.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049871577.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049874577.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049880145.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049875740.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_049869939.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049865803.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_049877706.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049866719.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049865062.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_049866633.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049873906.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049867984.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049868522.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049873595.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_049880016.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049878115.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_049867654.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049884940.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049881874.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049883439.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049877826.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-532668;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585	"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G"
XP_049873188.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049884281.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049865099.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049885648.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049887078.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049865234.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049872522.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_049878942.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049882101.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049878439.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049875365.1	13	KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5690	"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)"
XP_049884272.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_049867413.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_049878891.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_049885255.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885541.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049885109.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049879255.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049868714.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873834.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049868507.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049880315.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049877818.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049870358.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_049873280.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049884961.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_049865063.1	15	MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40	"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism"
XP_049885990.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049867178.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049867632.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049867326.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049875739.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049879287.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049874978.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049879704.1	5	Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560	"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival"
XP_049883864.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049868923.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049874958.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049873889.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049868542.1	7	Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36	"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_049868973.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723	"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation"
XP_049877861.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049883689.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049874761.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049877590.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049877552.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_049866525.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_049879237.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049867523.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049867590.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049885895.1	8	MetaCyc: PWY-5154;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-5;MetaCyc: PWY-7400;MetaCyc: PWY-4983	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)"
XP_049874114.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049869299.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870	"Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins"
XP_049878440.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887598.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049872233.1	1	Reactome: R-HSA-977225	"Amyloid fiber formation"
XP_049869533.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630222	"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding"
XP_049885388.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049870647.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049885145.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049872462.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049870345.1	1	KEGG: 00230+3.1.4.53	"Purine metabolism"
XP_049880645.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049882541.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022538	"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA"
XP_049868333.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049870737.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397	"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Polymerase switching";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049876114.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049879092.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049875274.1	3	MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2	"Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism"
XP_049886238.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049877714.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_049879202.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049865308.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_049875221.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049872312.1	8	KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049876136.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_049881333.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049881701.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049875876.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049872559.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049887257.1	13	Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;KEGG: 04926+2.7.11.1	"G alpha (12/13) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"Relaxin signaling pathway"
XP_049867123.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_049876117.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_049873264.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049871588.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049869637.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049877893.1	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_049874070.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049873202.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049870947.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049875132.1	9	Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_049867696.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049888090.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049886024.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144	"Xenobiotics";"Endogenous sterols";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling"
XP_049868906.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_049885142.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049888131.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049867794.1	6	Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731	"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Starch degradation III"
XP_049874062.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049879599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049876707.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049881207.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049866588.1	7	Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867	"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex"
XP_049876558.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049868738.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883898.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049878478.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049866853.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_049871862.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049887601.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049881419.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049876240.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049866583.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049887530.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049885226.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_049873155.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_049882124.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049875031.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049885144.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049875027.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049866764.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887858.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_049875926.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049879324.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049873750.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_049881692.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049869165.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_049868751.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049866746.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049874101.1	17	Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397	"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_049883681.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049875907.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049869278.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049879889.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_049872466.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049878951.1	12	Reactome: R-HSA-400253;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-163560;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Circadian Clock";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Triglyceride catabolism";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049881911.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_049866425.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events"
XP_049877914.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049884851.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049877141.1	2	Reactome: R-HSA-606279;Reactome: R-HSA-6783310	"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway"
XP_049880217.1	17	Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_049883641.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049887593.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049886945.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049878815.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_049882007.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049878792.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049871483.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_049886106.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_049869721.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049873876.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049878898.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049887759.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801	"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD"
XP_049887407.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049875174.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049882345.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869532.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091	"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells"
XP_049868917.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_049882266.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_049865152.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049868742.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049881347.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049884856.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_049888141.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049880009.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049867792.1	6	MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-7238	"Starch degradation V";"Glycogen degradation II";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II"
XP_049882553.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049865688.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049867431.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_049870134.1	7	Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2	"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Oxidative phosphorylation"
XP_049877806.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_049882682.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-2151201;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-9633012;Reactome: R-HSA-450341;Reactome: R-HSA-400253;Reactome: R-HSA-3214847	"Regulation of PTEN gene transcription";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Activation of the AP-1 family of transcription factors";"Circadian Clock";"HATs acetylate histones"
XP_049873580.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049873808.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18	"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes"
XP_049874667.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049872077.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049882299.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049868321.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049885813.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049864857.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049867795.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_049885716.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049869666.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049865130.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049867756.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049875131.1	9	Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323	"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol"
XP_049879848.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049876063.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_049866895.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_049867971.1	5	Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3	"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049868175.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049886226.1	4	Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
XP_049881587.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049874051.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049871689.1	10	MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841	"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Folate transformations II (plants)"
XP_049865603.1	3	MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049870470.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5358752	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated"
XP_049886005.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049875190.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049870841.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049885694.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392	"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II"
XP_049874609.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049878126.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_049887501.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049884797.1	6	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_049872002.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_049869195.1	8	MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7734;MetaCyc: PWY-7733;KEGG: 00630+3.5.1.9	"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxyquinaldate biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_049864904.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049883837.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049883202.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049876151.1	4	KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50	"Arginine and proline metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_049866840.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049878369.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049888019.1	22	MetaCyc: PWY-5353;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-7606;MetaCyc: PWY-7036	"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_049885540.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049871656.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049864967.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_049887735.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049881383.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049882598.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049875107.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049873219.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049866718.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049886267.1	24	Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-418597	"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"G alpha (z) signalling events"
XP_049879933.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_049866058.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049866659.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049883732.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049883575.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_049875094.1	16	Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049881763.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_049875812.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_049885490.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_049872538.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049869050.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049880824.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135	"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER"
XP_049884626.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049868966.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593	"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity"
XP_049865119.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049880559.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667	"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I"
XP_049871553.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049870629.1	11	Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246	"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049887466.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049878186.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049866916.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049879909.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049880738.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049879227.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049877147.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049886118.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049874542.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_049883187.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049886347.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049870167.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049874043.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049878298.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049872997.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049868730.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_049872171.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_049880719.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049867789.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049870665.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168276	"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways"
XP_049874351.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049864913.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9610379	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events"
XP_049879720.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049868097.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049875180.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049878627.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_049883831.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049884678.1	11	Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455	"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism"
XP_049871889.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049881796.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049879218.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049876014.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_049866950.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049886036.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049867615.1	11	MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6549	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III"
XP_049874833.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049866093.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049869123.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049877132.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_049876325.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049877909.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_049865563.1	5	MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451	"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis"
XP_049877316.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions"
XP_049881636.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049883449.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049870317.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition"
XP_049869179.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049878712.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049876738.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-72163	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway"
XP_049879866.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_049877374.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049875789.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049868679.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049867867.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049865344.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_049883685.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049879931.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049880033.1	24	Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436	"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Separation of Sister Chromatids";"Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049865474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865604.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_049875098.1	16	Reactome: R-HSA-3214847;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565	"HATs acetylate histones";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049872006.1	12	Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862;Reactome: R-HSA-982772	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling";"Signaling by EGFR";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Growth hormone receptor signaling"
XP_049872038.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049887431.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049884702.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049882937.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049876113.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_049883199.1	18	KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;MetaCyc: PWY-5690;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-7384	"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Neutrophil degranulation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_049867402.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049868606.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049874263.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049882184.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049882168.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_049875973.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049865003.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049877536.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049879222.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049883829.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049868874.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049865265.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_049879208.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049878894.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_049879058.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049866879.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049866260.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049885127.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049885172.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049882477.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049877756.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049880516.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049872616.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049866384.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881912.1	5	MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_049867817.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049871472.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049869607.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049878915.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation"
XP_049876201.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049882110.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_049865124.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049875469.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_049874348.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049866399.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_049869593.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049881598.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-419771	"G alpha (i) signalling events";"Opsins"
XP_049872612.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049870210.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_049887688.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049868916.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049865391.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_049877593.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049877496.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049879116.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857	"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_049886389.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049876412.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_049868642.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049877322.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049870563.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049875811.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049874741.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049873112.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-68827	"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex"
XP_049867386.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs"
XP_049884839.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049868218.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049874059.1	4	Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049878981.1	6	KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11	"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_049865571.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049870404.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049869967.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049882059.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049876083.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049874822.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049873643.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049866685.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049874004.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_049887734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049867410.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_049886883.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049873810.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049885083.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049865210.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049871625.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049866387.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049868857.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049869755.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-975634	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport"
XP_049880718.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049877181.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049886125.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049869531.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049886937.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049883024.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049874252.1	2	KEGG: 00513+2.4.1.142;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_049886103.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049881597.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049880423.1	14	Reactome: R-HSA-1483213;MetaCyc: PWY-8051;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4	"Synthesis of PE";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism"
XP_049879128.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049879752.1	11	KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049876586.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049876781.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049872448.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049888072.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866073.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049876316.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_049881417.1	5	Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049877039.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049879163.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_049877648.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049864974.1	3	Reactome: R-HSA-194313;Reactome: R-HSA-114608;Reactome: R-HSA-195399	"VEGF ligand-receptor interactions";"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization"
XP_049887500.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049880744.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049877917.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049873635.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049887399.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_049874707.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049888117.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049864852.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049871744.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049867463.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049872371.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_049869829.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049873128.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-380284	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049876153.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_049877514.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897	"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes"
XP_049878165.1	6	Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation"
XP_049869358.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049874731.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049882094.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049880637.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049870195.1	2	KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_049876639.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_049873819.1	28	Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-69473	"Dual incision in TC-NER";"Meiotic recombination";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint"
XP_049887405.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049874525.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049878074.1	3	Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation"
XP_049865388.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049867972.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events"
XP_049887694.1	6	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-5632684	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state"
XP_049881505.1	8	Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_049887144.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049884811.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049887256.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049884164.1	8	Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_049882159.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049878818.1	7	KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism"
XP_049881606.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049874331.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049874643.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049865436.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049869508.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049874975.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049866951.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049865836.1	5	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;Reactome: R-HSA-112409	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation"
XP_049869056.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049870861.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049880944.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_049880595.1	6	MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_049879250.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049869317.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8939902	"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity"
XP_049879140.1	12	KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484	"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_049880851.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049864864.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049877499.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_049885931.1	14	MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11	"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis"
XP_049884048.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_049879293.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Intraflagellar transport";"Macroautophagy";"COPI-mediated anterograde transport"
XP_049865892.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049881310.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049867653.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049885836.1	12	KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1	"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Methane metabolism"
XP_049886755.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049865370.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling"
XP_049887887.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049885085.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049885566.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049877450.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049887298.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049873560.1	16	Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-1622;MetaCyc: PWY-2221;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11	"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Methane metabolism";"Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_049869270.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049879320.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049874523.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049883620.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049867966.1	6	Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-381426	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_049873551.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_049880362.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"G alpha (i) signalling events";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_049886016.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049882450.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_049877489.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049881211.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049865807.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis"
XP_049870403.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049882130.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_049887408.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049870676.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049879458.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA"
XP_049880581.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049867480.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881963.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049887414.1	4	Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_049884879.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049884939.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049869638.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion"
XP_049872185.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049868868.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049865802.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_049866298.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_049875286.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_049884612.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049865039.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049865790.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049874155.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049881329.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049869492.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594	"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events"
XP_049887592.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_049873428.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049881610.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-975634	"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Chylomicron assembly";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"VLDL assembly";"Chylomicron remodeling";"Scavenging by Class H Receptors";"VLDL clearance";"Clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Retinoid metabolism and transport"
XP_049877642.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049875813.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049865060.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_049885252.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879433.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049867479.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049870397.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049883646.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049865531.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-6798695	"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation"
XP_049874962.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049877481.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049864859.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049879715.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049887838.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049875834.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049868358.1	4	Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049875524.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049873969.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;Reactome: R-HSA-196836	"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism"
XP_049885614.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873185.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_049872205.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049887243.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_049871956.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049872407.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis"
XP_049880529.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049886145.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881444.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049876565.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_049866714.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_049881034.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049868469.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-977225	"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Amyloid fiber formation"
XP_049871607.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049883552.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049867385.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049886983.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_049866449.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049871565.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756	"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation"
XP_049876946.1	10	KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174	"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)"
XP_049876872.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_049867345.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;MetaCyc: PWY-7511	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination"
XP_049881591.1	3	Reactome: R-HSA-8963901;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Chylomicron remodeling";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_049885392.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560	"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism"
XP_049885590.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex"
XP_049879773.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5	"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_049887738.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049879072.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2"
XP_049878939.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway"
XP_049873415.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049882501.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866634.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049884918.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049878893.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_049878236.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049876487.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049872912.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049874937.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049882734.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_049879972.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049881504.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049874842.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_049887558.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_049876958.1	5	KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism"
XP_049867834.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_049882410.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049865233.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049872096.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049883014.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049873295.1	6	KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_049887514.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049883381.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049868626.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049873433.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-5136	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049874724.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049875295.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049878508.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049879714.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049877723.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049874973.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_049874008.1	17	MetaCyc: PWY-6620;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644;MetaCyc: PWY-5532	"Guanine and guanosine salvage";"Salinosporamide A biosynthesis";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine catabolism";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Nucleoside and nucleotide degradation (archaea)"
XP_049881062.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049869636.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_049866327.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049873913.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049865870.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049877465.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049888071.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049866780.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_049876562.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049880041.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049871824.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049878424.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_049874328.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049867395.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049868980.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880	"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases"
XP_049875602.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049874641.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049883833.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049869783.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049865636.1	8	MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6	"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms"
XP_049867625.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049886876.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_049867366.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049880800.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049874757.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049874391.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049882969.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049873527.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_049887227.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-5689880	"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"Ub-specific processing proteases"
XP_049867708.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049887506.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049879801.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_049879994.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049881696.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-419771	"G alpha (i) signalling events";"Opsins"
XP_049867422.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049887126.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_049865123.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049869304.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_049879687.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110331	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Cleavage of the damaged purine"
XP_049880166.1	7	KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921	"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_049882912.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049878769.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049882709.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049880209.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_049887362.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049880043.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049887199.1	16	MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5749;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5	"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Itaconate degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_049879977.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049876267.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049874694.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_049874832.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049874003.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_049884871.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-6811434;Reactome: R-HSA-167172;Reactome: R-HSA-6807878;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"COPI-dependent Golgi-to-ER retrograde traffic";"Transcription of the HIV genome";"COPI-mediated anterograde transport";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_049882531.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049881251.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049867060.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049882755.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_049886020.1	29	Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953	"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation"
XP_049876965.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_049877516.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15	"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_049871473.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049869016.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049873146.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049875743.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049883875.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-69601	"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_049886257.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049867320.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049870968.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049884015.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_049881454.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins"
XP_049881462.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049875712.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049881633.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049870049.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_049867780.1	12	Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719	"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors"
XP_049866789.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_049873766.1	18	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4	"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism"
XP_049873061.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_049886748.1	5	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-7082	"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_049873858.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_049869780.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049887005.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_049878806.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049871999.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_049873475.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049880190.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049875459.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768	"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049865215.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049868295.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism"
XP_049865585.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049867652.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_049865353.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_049876073.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049877565.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049883201.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049881663.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_049868326.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049871011.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049866450.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049882033.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049885744.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events"
XP_049879190.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049867079.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_049882556.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049886298.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049868222.1	4	Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049868608.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049867434.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_049885650.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049868741.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_049867280.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049879969.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049879266.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049866584.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049869521.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049869803.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049868968.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9022692	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity"
XP_049879776.1	11	KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis"
XP_049883103.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049870646.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049878648.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049873826.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049871453.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049885259.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049874292.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_049882765.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049878287.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049880207.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049885941.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049886014.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604	"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling"
XP_049869691.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049873535.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049871406.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_049873207.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_049867389.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049866729.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049884422.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport"
XP_049881967.1	13	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis"
XP_049877769.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049874838.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049867091.1	44	Reactome: R-HSA-162658;Reactome: R-HSA-74749;Reactome: R-HSA-6802955;Reactome: R-HSA-456926;Reactome: R-HSA-202670;Reactome: R-HSA-3371453;Reactome: R-HSA-5668599;Reactome: R-HSA-1295596;Reactome: R-HSA-375165;Reactome: R-HSA-879415;Reactome: R-HSA-5654732;Reactome: R-HSA-112409;Reactome: R-HSA-5674499;Reactome: R-HSA-9635465;Reactome: R-HSA-9649948;Reactome: R-HSA-2871796;Reactome: R-HSA-5654727;Reactome: R-HSA-6802952;Reactome: R-HSA-5654733;Reactome: R-HSA-9627069;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-8939211;Reactome: R-HSA-9634638;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-8940973;Reactome: R-HSA-5675221;Reactome: R-HSA-2559582;Reactome: R-HSA-2029482;Reactome: R-HSA-5654726;Reactome: R-HSA-5663213;Reactome: R-HSA-445144;KEGG: 04150+2.7.11.24;Reactome: R-HSA-198753;Reactome: R-HSA-444257;Reactome: R-HSA-2559585;Reactome: R-HSA-170968;Reactome: R-HSA-8943724;Reactome: R-HSA-5673001;Reactome: R-HSA-5674135;Reactome: R-HSA-6811558;Reactome: R-HSA-982772;Reactome: R-HSA-6802946	"Golgi Cisternae Pericentriolar Stack Reorganization";"Signal attenuation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thrombin signalling through proteinase activated receptors (PARs)";"ERKs are inactivated";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate NADPH Oxidases";"Spry regulation of FGF signaling";"NCAM signaling for neurite out-growth";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR3 signaling";"RAF-independent MAPK1/3 activation";"Negative feedback regulation of MAPK pathway";"Suppression of apoptosis";"Signaling downstream of RAS mutants";"FCERI mediated MAPK activation";"Negative regulation of FGFR2 signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR4 signaling";"Regulation of the apoptosome activity";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"ESR-mediated signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"RUNX2 regulates osteoblast differentiation";"Negative regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of FGFR1 signaling";"RHO GTPases Activate WASPs and WAVEs";"Signal transduction by L1";"mTOR signaling pathway";"ERK/MAPK targets";"RSK activation";"Oncogene Induced Senescence";"Frs2-mediated activation";"Regulation of PTEN gene transcription";"RAF/MAP kinase cascade";"MAP2K and MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Growth hormone receptor signaling";"Signaling by moderate kinase activity BRAF mutants"
XP_049885156.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049870874.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049885623.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049879706.1	5	Reactome: R-HSA-209543;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560	"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival"
XP_049876919.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_049872537.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_049880804.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049865808.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_049886296.1	10	MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism"
XP_049872059.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168	"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049867777.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_049865422.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_049882472.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049867514.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_049872406.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_049885220.1	6	KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_049873978.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887532.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_049887840.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049865843.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_049866688.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049879220.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049884798.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049876743.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049872310.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049869379.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049876147.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN"
XP_049869892.1	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049868799.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_049873651.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049879389.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049881721.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_049881819.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049888140.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049882751.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049880557.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_049869662.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_049884755.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049876828.1	13	Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-382556;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-5362768	"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"HSF1 activation";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Neutrophil degranulation";"Protein methylation";"ABC-family proteins mediated transport";"Josephin domain DUBs";"Ovarian tumor domain proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049883021.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049879162.1	4	KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism"
XP_049873167.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049867298.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_049871296.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049885847.1	7	MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456	"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylketonuria"
XP_049872985.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Disinhibition of SNARE formation"
XP_049873662.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049875096.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-201722	"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex"
XP_049882714.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_049871677.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049880964.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049882506.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049871484.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049882845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049887010.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049887073.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049884758.1	13	KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-5133	"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Ethanol oxidation";"Propanoate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis"
XP_049868466.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049881605.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049867133.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049878685.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049868579.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049867626.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049868582.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049877539.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049877936.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049882098.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049888177.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_049880553.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049878643.1	7	Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049885265.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049885496.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049886180.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_049872921.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049881443.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049879275.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049879907.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049874468.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049872190.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049867876.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_049879950.1	18	Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-8053	"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Anandamide biosynthesis II"
XP_049872010.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049869216.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049866386.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881448.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049879050.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049867444.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049887231.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049869488.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049881447.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049865224.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049880212.1	6	MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791	"UMP biosynthesis I";"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_049888039.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049874819.1	6	Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"Circadian Clock";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_049873756.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism"
XP_049876131.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049874420.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_049874989.1	9	KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599	"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Pyruvate metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency"
XP_049884659.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049873270.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049878354.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947	"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049876934.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049869605.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049881445.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049871504.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049871543.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_049867549.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
YP_010449136.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049874929.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_049885952.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049882947.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_049865559.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148	"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049879932.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_049869968.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_049882509.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876105.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049865225.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049873515.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049880334.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049882337.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049873040.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556	"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport"
XP_049881862.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_049869002.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Ub-specific processing proteases";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_049866106.1	13	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Purine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism"
XP_049865576.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049869606.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_049883820.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049877755.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049877142.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049877701.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049868821.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_049883584.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049867920.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049873837.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049873351.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049870972.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049883505.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049881179.1	2	Reactome: R-HSA-3299685;Reactome: R-HSA-211945	"Detoxification of Reactive Oxygen Species";"Phase I - Functionalization of compounds"
XP_049884799.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049886258.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049870519.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049872606.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049876556.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049880997.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049875175.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_049878867.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049877340.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049865400.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049876955.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_049882076.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049865466.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049881826.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049865763.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049870873.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049867552.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_049881957.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_049876326.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049872170.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049885174.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_049867509.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_049865054.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880450.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049881825.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049880024.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049873666.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049884873.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_049868598.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049877509.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049871574.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049885960.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_049878009.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049875161.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049885755.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_049871456.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049880172.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049887535.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049871308.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049879831.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049870259.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049873598.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6	"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation"
XP_049882280.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049887739.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866590.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359463	"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_049870200.1	6	Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52	"Serine biosynthesis";"Vitamin B6 metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_049873997.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049884656.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049874161.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049875108.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049874831.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049888089.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049885141.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049878888.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_049881030.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_049883476.1	11	MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_049868763.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049877417.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049877797.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_049868829.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_049869017.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049883175.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049887682.1	11	MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7268	"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049875607.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049880977.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049877670.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049866553.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049887584.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049873499.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049872239.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049868207.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049877576.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049869118.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049868840.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049877180.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049866896.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_049878028.1	7	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522	"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049874368.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_049870268.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049876570.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
YP_010449126.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049869718.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049865153.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049867996.1	14	Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-399997;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"Phosphatidylinositol signaling system"
XP_049886546.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049876939.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049870166.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049887403.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049878933.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049880410.1	10	Reactome: R-HSA-913709;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360	"O-linked glycosylation of mucins";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_049884826.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049880422.1	2	KEGG: 04150+2.7.11.24;Reactome: R-HSA-5687128	"mTOR signaling pathway";"MAPK6/MAPK4 signaling"
XP_049881457.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049873905.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049880039.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049870626.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_049885118.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049882908.1	7	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-69205;MetaCyc: PWY-6614	"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis"
XP_049878442.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887599.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049883359.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049880424.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4	"Anandamide biosynthesis I";"Synthesis of PE";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_049872941.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_049881727.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_049866409.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049885627.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049880643.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049876056.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6361;MetaCyc: PWY-6554;MetaCyc: PWY-6369;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_049878868.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049887271.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049879585.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049884211.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9646399	"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recycling pathway of L1";"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Aggrephagy"
XP_049870753.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_049879709.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism"
XP_049877717.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049886365.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049871439.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_049866692.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884910.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049866555.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049878431.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_049879454.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_049867759.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_049873646.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049871948.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049882326.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-7852	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)"
XP_049871044.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_049878952.1	12	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-163560;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-400253;Reactome: R-HSA-2500257	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Triglyceride catabolism";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Circadian Clock";"Resolution of Sister Chromatid Cohesion"
XP_049881662.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049866279.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_049887600.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_049877373.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877553.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049875732.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049873609.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_049875838.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049882167.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_049880562.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_049881585.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049866769.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_049884761.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049876692.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049867957.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049884898.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049874135.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_049888043.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_049872525.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049866835.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_049873401.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049877337.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049882395.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049873411.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049876860.1	13	KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation"
XP_049865527.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865230.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866717.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049868603.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049877633.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049877996.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049882681.1	8	Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-6796648;Reactome: R-HSA-2151201;Reactome: R-HSA-8943724;Reactome: R-HSA-9018519;Reactome: R-HSA-9633012;Reactome: R-HSA-450341	"Circadian Clock";"HATs acetylate histones";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional activation of mitochondrial biogenesis";"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Activation of the AP-1 family of transcription factors"
XP_049865319.1	14	MetaCyc: PWY-5104;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5108;MetaCyc: PWY-5103;MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057	"L-isoleucine biosynthesis IV";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-valine degradation II"
XP_049870867.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049887475.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049879059.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_049872411.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049884947.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049881761.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049867832.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_049876112.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049866664.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-3000171	"ECM proteoglycans";"Collagen chain trimerization";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Extracellular matrix organization";"Signaling by PDGF";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions"
XP_049866569.1	10	KEGG: 00250+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6537;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536	"Alanine, aspartate and glutamate metabolism";"Degradation of GABA";"Propanoate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"Butanoate metabolism";"L-glutamate degradation IV";"beta-Alanine metabolism";"4-aminobutanoate degradation III"
XP_049883221.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_049878102.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049878713.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049885011.1	4	Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123	"Neutrophil degranulation";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"
XP_049881465.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049865043.1	30	Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-2122947;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761	"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"NOTCH1 Intracellular Domain Regulates Transcription";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"Neddylation";"Downstream TCR signaling";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049888017.1	22	MetaCyc: PWY-7049;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7728;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7726;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis"
XP_049885182.1	12	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049880771.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049888101.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049865248.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049872972.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_049877305.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049870965.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049874570.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049870671.1	4	KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270	"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate"
XP_049871423.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876933.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_049871650.1	8	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_049882728.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049881503.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049877411.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript"
XP_049884965.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049867764.1	32	Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-72163	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway"
XP_049886332.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_049871451.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049882128.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049885630.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049872209.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs"
XP_049886377.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049879743.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_049876260.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049865072.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_049866722.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049873974.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-6370	"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)"
XP_049878018.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049885921.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049868596.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049869325.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867871.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049872496.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876864.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_049872341.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049870859.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049883822.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049883602.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049879305.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Macroautophagy";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection"
XP_049872149.1	18	Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049871468.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049875144.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739;Reactome: R-HSA-6787639;MetaCyc: PWY-5738	"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis"
XP_049874720.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_049869137.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049885116.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049885620.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865427.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049872838.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_049886219.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049880478.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049866762.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_049877637.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049884624.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049878341.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049864855.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049870205.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor"
XP_049867050.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049868276.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049885527.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049880596.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_049880369.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049877804.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_049885254.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885898.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049878182.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049877069.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049886483.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_049883726.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049885733.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049877634.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049874584.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049872575.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049871443.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity"
XP_049884176.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049882011.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049866396.1	5	MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
XP_049882093.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049870566.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism"
XP_049870943.1	5	Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110381	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_049882645.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049881303.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049888132.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049871929.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-182218	"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation"
XP_049879944.1	5	Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_049864901.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049866820.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049877639.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_049865709.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_049877798.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_049876069.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049877607.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049874960.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049865246.1	3	Reactome: R-HSA-2206291;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096	"MPS IIIC - Sanfilippo syndrome C";"Neutrophil degranulation";"HS-GAG degradation"
XP_049868082.1	4	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_049867650.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049877542.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049865009.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049866581.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_049873339.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II"
XP_049873197.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049865258.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049887235.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_049866440.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880579.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049875609.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049884733.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049883842.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_049869189.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226	"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049872400.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519	"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression"
XP_049885253.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049867089.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049887681.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51	"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism"
XP_049881742.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049867002.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049876690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049866806.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_049879765.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5	"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049869294.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049874173.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049872465.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049887488.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049867781.1	12	Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719	"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors"
XP_049887946.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381183	"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_049873281.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049870447.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_049883727.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049884379.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049869102.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049869831.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_049876871.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_049865148.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_049866307.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_049872094.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049876081.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049869493.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049881206.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049873151.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049878980.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_049877935.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_049869499.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_049865340.1	3	Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8	"Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation"
XP_049880386.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-69166	"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate"
XP_049875068.1	5	KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578	"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_049886201.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_049884286.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_049885725.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049882607.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049882003.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_049886342.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_049865586.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049876469.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049879500.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1	"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II"
XP_049878741.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_049870882.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_049867036.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049880971.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_049875720.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049881210.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049873023.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049871000.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_049883164.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049864956.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049880803.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049865787.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049879961.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049870630.1	11	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_049879621.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049866969.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049867327.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049883394.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049865217.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049887187.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858	"Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines"
XP_049879102.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049876846.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
YP_010449130.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_049887712.1	11	Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359	"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation"
XP_049865882.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049883448.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049880603.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049866096.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049865661.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049871978.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049868766.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049869713.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049868305.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049865271.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049885140.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_049866908.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049888009.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol"
XP_049871752.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049882917.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049876324.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_049884677.1	11	Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539	"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism"
XP_049872401.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049871655.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_049888241.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049883599.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866140.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_049870486.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664	"Iron uptake and transport";"UCH proteinases";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Neddylation"
XP_049875694.1	7	KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049864856.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049879580.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049886266.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-8964315;Reactome: R-HSA-163359;Reactome: R-HSA-416482	"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through BTK";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events"
XP_049880030.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049868584.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049874063.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049882562.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049886218.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049886117.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049884290.1	7	MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis"
XP_049881631.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049864888.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049870027.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049879203.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049882524.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866888.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049869520.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633	"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049881694.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049873214.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_049871678.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_049874574.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049872782.1	6	KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_049887460.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049876922.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049885375.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049873183.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049887996.1	5	KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049873777.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049884210.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332	"Aggrephagy";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Gap junction assembly";"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin"
XP_049869442.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049888234.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049879863.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049879225.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049869859.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049873336.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049865392.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049881117.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049870321.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049875548.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049877505.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049869980.1	6	KEGG: 00040+5.1.3.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336	"Pentose and glucuronate interconversions";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049876608.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049872060.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168	"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887931.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049864953.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049872008.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049868176.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049868877.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049865128.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049887908.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits"
XP_049879170.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8934593	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity"
XP_049883583.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049885580.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049878540.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049888095.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049871987.1	58	Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5689901;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974	"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Metalloprotease DUBs";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Orc1 removal from chromatin";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"ER-Phagosome pathway"
XP_049869580.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_049879797.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_049868919.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049880530.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_049877022.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_049876087.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049880707.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049867616.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049875289.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_049872640.1	23	Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-381676;Reactome: R-HSA-392851	"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (s) signalling events";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor"
XP_049870007.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049871493.1	7	KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis"
XP_049872409.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_049879711.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049877937.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_049869672.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_049879911.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049868015.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049874193.1	13	KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)"
XP_049877868.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049871600.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_049869001.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Ub-specific processing proteases"
XP_049877400.1	4	KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol"
XP_049880962.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049878125.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_049870283.1	31	MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5147	"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)"
XP_049869160.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049881042.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049871134.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_049886942.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049872589.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049884474.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049866629.1	29	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-6804760;Reactome: R-HSA-3371453;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-912446;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Methylation";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Sensing of DNA Double Strand Breaks";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)"
XP_049866939.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049879841.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049868601.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049871212.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049868861.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049877831.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049883640.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049874082.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-159227	"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA"
XP_049869642.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049873149.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049877871.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_049883095.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887744.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049864882.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049865156.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049880407.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049879771.1	11	KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049866982.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_049874030.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049865529.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049874104.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049883128.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome"
XP_049868081.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049887007.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_049881744.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049870436.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-7356;Reactome: R-HSA-196819	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism"
XP_049867134.1	11	Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5	"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_049868019.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049888126.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110373	"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_049878383.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049887786.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis"
XP_049882724.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049867399.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049866872.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049872314.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_049881324.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_049870982.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049879139.1	12	KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_049872455.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_049883622.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049886206.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049887502.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049875974.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049884463.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049883574.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049865906.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049865776.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_049878913.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049876062.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049872700.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_049865917.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049885439.1	6	MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261	"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol degradation I"
XP_049874309.1	11	Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-5628897	"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes"
XP_049885996.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049878460.1	20	Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-174411	"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere"
XP_049884475.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873507.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049867411.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_049869875.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_049884831.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049883690.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_049879481.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_049871494.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_049872763.1	24	Reactome: R-HSA-5621575;Reactome: R-HSA-9010642;Reactome: R-HSA-5610780;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-9634600;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;Reactome: R-HSA-422356;Reactome: R-HSA-5610783;Reactome: R-HSA-381676;Reactome: R-HSA-392517;Reactome: R-HSA-8963896;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.11;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-163560;Reactome: R-HSA-442720;Reactome: R-HSA-8853659	"CD209 (DC-SIGN) signaling";"ROBO receptors bind AKAP5";"Degradation of GLI1 by the proteasome";"PKA activation";"PKA-mediated phosphorylation of CREB";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"Regulation of insulin secretion";"Degradation of GLI2 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Rap1 signalling";"HDL assembly";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"mTOR signaling pathway";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Triglyceride catabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"RET signaling"
XP_049884701.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049880278.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049866684.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049881593.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049866556.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049883926.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049867066.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049868150.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049885950.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_049888102.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049876075.1	8	KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis"
XP_049880511.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049871578.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049875130.1	9	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049881337.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049877323.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049872910.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049877720.1	13	MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III"
XP_049874118.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049877883.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049883922.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy"
XP_049881607.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049870495.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis"
XP_049879200.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049877367.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049887952.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_049868274.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049865069.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_049871474.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049882191.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049868359.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049874192.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation"
XP_049869010.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049883073.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049878023.1	7	KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_049869305.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_049887507.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049874688.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_049874606.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049877433.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049885107.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049881075.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049886884.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_049869209.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_049888036.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049886083.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_049876283.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049873271.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049865131.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049870201.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_049866723.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_049884192.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_049883579.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_049887662.1	7	KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-4984	"Arginine biosynthesis";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Canavanine degradation";"Putrescine biosynthesis III";"Urea cycle"
XP_049868744.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049868330.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049873293.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate"
XP_049879660.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_049868749.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049865591.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049872701.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_049884613.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_049865946.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_049881898.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049882546.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049879778.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049884112.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049870168.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_049870105.1	5	MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943	"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates"
XP_049877420.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_049881377.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049870253.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049869190.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_049883165.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497	"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_049877694.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049882644.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049870562.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_049867550.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049881601.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049872456.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049873655.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049869443.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049867209.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_049871019.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049871955.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049884922.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049871963.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_049876769.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110328	"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_049883560.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049875810.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049882561.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_049874315.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049887468.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049865793.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049876176.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049885997.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049877235.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049875944.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_049870090.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049880861.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049880525.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049879281.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049875285.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049888232.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049873413.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049877944.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049878469.1	19	MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7205;Reactome: R-HSA-380320;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7226;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Purine metabolism";"UTP and CTP de novo biosynthesis"
XP_049882474.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049876458.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049869182.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_049878326.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049885041.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049888160.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_049881506.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167287	"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery"
XP_049886227.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_049877757.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049874633.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867325.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049881301.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049872814.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_049870279.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_049868636.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049876066.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_049884712.1	11	Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795	"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling"
XP_049877929.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049887444.1	18	KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1	"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Sulfolactate degradation III";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_049878423.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_049875748.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049867651.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049865589.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049866956.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_049883188.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN"
XP_049870931.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049865786.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049884765.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_049883127.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_049869742.1	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_049872519.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049880598.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049865212.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049866528.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9609736	"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors"
XP_049877163.1	10	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7328;Reactome: R-HSA-5609977	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose detoxification";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_049879991.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049868872.1	31	MetaCyc: PWY-5994;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-5367;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-5971	"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_049882727.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049882788.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_049870966.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049876790.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049869446.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869487.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_049874065.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-163615	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation"
XP_049878053.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_049887166.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049878007.1	11	Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68952	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"DNA replication initiation"
XP_049866767.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049878386.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049876756.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049873673.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049886236.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049871241.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049887487.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_049888008.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049873576.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574	"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II"
XP_049875681.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049867627.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049868001.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049870091.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism"
XP_049868764.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_049872829.1	182	Reactome: R-HSA-3785653;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-209560;Reactome: R-HSA-110312;Reactome: R-HSA-69231;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-175474;Reactome: R-HSA-4641263;Reactome: R-HSA-912631;Reactome: R-HSA-211733;Reactome: R-HSA-8849469;Reactome: R-HSA-174184;Reactome: R-HSA-975144;Reactome: R-HSA-9013973;Reactome: R-HSA-3322077;Reactome: R-HSA-6804760;Reactome: R-HSA-937042;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-5685942;Reactome: R-HSA-9645460;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-5656169;Reactome: R-HSA-5607764;Reactome: R-HSA-2173796;Reactome: R-HSA-6807004;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8856828;Reactome: R-HSA-8863795;Reactome: R-HSA-2408557;Reactome: R-HSA-977225;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-1236974;Reactome: R-HSA-975957;Reactome: R-HSA-5696395;Reactome: R-HSA-180585;Reactome: R-HSA-6782210;Reactome: R-HSA-69541;Reactome: R-HSA-174178;Reactome: R-HSA-5693607;Reactome: R-HSA-8941858;Reactome: R-HSA-2691232;Reactome: R-HSA-9637628;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-2173795;Reactome: R-HSA-8939236;Reactome: R-HSA-72764;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-901032;Reactome: R-HSA-8876493;Reactome: R-HSA-6781827;Reactome: R-HSA-72689;Reactome: R-HSA-5357905;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-9636383;Reactome: R-HSA-6791226;Reactome: R-HSA-5675482;Reactome: R-HSA-5689901;Reactome: R-HSA-6782135;Reactome: R-HSA-2894862;Reactome: R-HSA-8866654;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6781823;Reactome: R-HSA-1358803;Reactome: R-HSA-1169408;Reactome: R-HSA-936964;Reactome: R-HSA-8948751;Reactome: R-HSA-5689877;Reactome: R-HSA-450408;Reactome: R-HSA-2979096;Reactome: R-HSA-3134975;Reactome: R-HSA-168638;Reactome: R-HSA-201681;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2672351;Reactome: R-HSA-174490;Reactome: R-HSA-1236382;Reactome: R-HSA-9014325;Reactome: R-HSA-110314;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8866652;Reactome: R-HSA-9020702;Reactome: R-HSA-532668;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-5205685;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8948747;Reactome: R-HSA-209543;Reactome: R-HSA-202424;Reactome: R-HSA-975956;Reactome: R-HSA-69017;Reactome: R-HSA-400253;Reactome: R-HSA-1253288;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-5693565;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-5656121;Reactome: R-HSA-72695;Reactome: R-HSA-936440;Reactome: R-HSA-2122947;Reactome: R-HSA-68949;Reactome: R-HSA-450321;Reactome: R-HSA-8852276;Reactome: R-HSA-72706;Reactome: R-HSA-6804756;Reactome: R-HSA-917937;Reactome: R-HSA-382556;Reactome: R-HSA-937039;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-937041;Reactome: R-HSA-9613829;Reactome: R-HSA-5655862;Reactome: R-HSA-179409;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-5696400;Reactome: R-HSA-5654732;Reactome: R-HSA-5684264;Reactome: R-HSA-5696394;Reactome: R-HSA-8854050;Reactome: R-HSA-2559585;Reactome: R-HSA-2644606;Reactome: R-HSA-5696397;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8875360;Reactome: R-HSA-2559582;Reactome: R-HSA-9633012;Reactome: R-HSA-917729;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-2559580;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-110320;Reactome: R-HSA-182971;Reactome: R-HSA-5689896;Reactome: R-HSA-5654733;Reactome: R-HSA-450302;Reactome: R-HSA-192823;Reactome: R-HSA-174048;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;Reactome: R-HSA-6783310;Reactome: R-HSA-2173788;Reactome: R-HSA-975163;Reactome: R-HSA-975110;Reactome: R-HSA-1295596;Reactome: R-HSA-445989;Reactome: R-HSA-8951664;Reactome: R-HSA-205043;Reactome: R-HSA-8856825;Reactome: R-HSA-162588;Reactome: R-HSA-2122948;Reactome: R-HSA-2467813	"Myoclonic epilepsy of Lafora";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"NF-kB is activated and signals survival";"Translesion synthesis by REV1";"Cyclin D associated events in G1";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Assembly Of The HIV Virion";"Regulation of FZD by ubiquitination";"Regulation of signaling by CBL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TICAM1-dependent activation of IRF3/IRF7";"Glycogen synthesis";"Regulation of TP53 Activity through Methylation";"IRAK2 mediated activation of TAK1 complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"HDR through Homologous Recombination (HRR)";"Alpha-protein kinase 1 signaling pathway";"Ub-specific processing proteases";"Late endosomal microautophagy";"Termination of translesion DNA synthesis";"CLEC7A (Dectin-1) signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MET activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Clathrin-mediated endocytosis";"Downregulation of ERBB2 signaling";"Selenocysteine synthesis";"Amyloid fiber formation";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"ER-Phagosome pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of Incision Complex in GG-NER";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Stabilization of p53";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Processing of DNA double-strand break ends";"Regulation of RUNX3 expression and activity";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Modulation by Mtb of host immune system";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Eukaryotic Translation Termination";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"ER Quality Control Compartment (ERQC)";"InlA-mediated entry of Listeria monocytogenes into host cells";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of a pool of free 40S subunits";"Regulation of TNFR1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Prevention of phagosomal-lysosomal fusion";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of necroptotic cell death";"Metalloprotease DUBs";"Dual incision in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Formation of TC-NER Pre-Incision Complex";"Downregulation of ERBB2:ERBB3 signaling";"ISG15 antiviral mechanism";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of PTEN stability and activity";"Josephin domain DUBs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of innate immune responses to cytosolic DNA";"NOD1/2 Signaling Pathway";"TCF dependent signaling in response to WNT";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Stimuli-sensing channels";"Membrane binding and targetting of GAG proteins";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Interleukin-1 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Pink/Parkin Mediated Mitophagy";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN localization";"p75NTR recruits signalling complexes";"Downstream TCR signaling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"CDK-mediated phosphorylation and removal of Cdc6";"Circadian Clock";"Downregulation of ERBB4 signaling";"Asymmetric localization of PCP proteins";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLI";"Formation of the ternary complex, and subsequently, the 43S complex";"Negative regulators of DDX58/IFIH1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Orc1 removal from chromatin";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of TP53 Activity through Phosphorylation";"Iron uptake and transport";"ABC-family proteins mediated transport";"IRAK1 recruits IKK complex";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"IKK complex recruitment mediated by RIP1";"Chaperone Mediated Autophagy";"Translesion synthesis by POLK";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Dual Incision in GG-NER";"Negative regulation of FGFR3 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"DNA Damage Recognition in GG-NER";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oncogene Induced Senescence";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"InlB-mediated entry of Listeria monocytogenes into host cell";"Senescence-Associated Secretory Phenotype (SASP)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"Oxidative Stress Induced Senescence";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Translesion Synthesis by POLH";"EGFR downregulation";"Ovarian tumor domain proteases";"Negative regulation of FGFR4 signaling";"activated TAK1 mediates p38 MAPK activation";"Viral mRNA Translation";"APC/C:Cdc20 mediated degradation of Cyclin B";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Fanconi Anemia Pathway";"Downregulation of TGF-beta receptor signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Spry regulation of FGF signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Neddylation";"NRIF signals cell death from the nucleus";"Cargo recognition for clathrin-mediated endocytosis";"Budding and maturation of HIV virion";"Activated NOTCH1 Transmits Signal to the Nucleus";"Separation of Sister Chromatids"
XP_049876015.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_049875238.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049878209.1	6	MetaCyc: PWY-8088;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-2941	"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis II"
XP_049867275.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049888034.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_049882008.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049883010.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049867510.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_049880237.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049864940.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049878944.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049868219.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC"
XP_049879959.1	2	Reactome: R-HSA-3000178;MetaCyc: PWY-7511	"ECM proteoglycans";"Protein ubiquitination"
XP_049878289.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049875689.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-917977	"Insulin receptor recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling"
XP_049870180.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049879256.1	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI"
XP_049881208.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_049883503.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049873915.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049879337.1	52	Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-5250924;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-76061	"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV Transcription Initiation";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"B-WICH complex positively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_049875079.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049870045.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049874401.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049878132.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113	"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1"
XP_049866419.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I"
XP_049888193.1	3	Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985	"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose"
XP_049887422.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_049866742.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-1369062;Reactome: R-HSA-9029569	"HDL remodeling";"ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049866894.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378	"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling"
XP_049869495.1	5	Reactome: R-HSA-75896;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"Plasmalogen biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_049881175.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049873613.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049887147.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_049872706.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049886164.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_049873642.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_049881316.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049881339.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049870291.1	17	KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115	"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049883860.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_049867587.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_049881700.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_049876329.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049871440.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_049877064.1	7	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism"
XP_049866765.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049870430.1	8	Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-8941284;Reactome: R-HSA-5362798;Reactome: R-HSA-373080	"Hedgehog 'on' state";"Ligand-receptor interactions";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"RUNX2 regulates chondrocyte maturation";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)"
XP_049885183.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476	"Human papillomavirus infection";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (q) signalling events"
XP_049874799.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049873144.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049875279.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049871138.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049872953.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049879257.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049883388.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_049877002.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049865121.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049876137.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049881384.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_049878054.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-432142	"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL"
XP_049875981.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049878897.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049868644.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049883528.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049874552.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049866618.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049875335.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049873868.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049877619.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049878651.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049876177.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049875360.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049876077.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049874159.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049887264.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_049877080.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049881313.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083	"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions"
XP_049880160.1	7	KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"Arginine biosynthesis"
XP_049874313.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_049882847.1	4	KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20	"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism"
XP_049871318.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049876078.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049875025.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_049881818.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049873152.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049885456.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049875081.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_049866337.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049873718.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_049874856.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_049866834.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049867580.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531	"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus"
XP_049873213.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049883807.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049882967.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049881471.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049886378.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049885542.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049885563.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049874826.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895	"ER-Phagosome pathway";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis"
XP_049870010.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049879750.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049887409.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049865061.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105	"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation"
XP_049867948.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049879390.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049883025.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049875454.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_049866860.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049873328.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA"
XP_049879483.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis"
XP_049874329.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049874053.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464	"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins"
XP_049888171.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_049881751.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049881365.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_049875171.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_049866932.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049877112.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049876587.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049877881.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049875444.1	3	KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348	"Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition"
XP_049877712.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049876079.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049866720.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049874987.1	9	KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-196780	"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Biotin transport and metabolism"
XP_049880509.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049883643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049867344.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049883625.1	17	KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-196780	"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism"
XP_049866925.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Arginine and proline metabolism"
XP_049879861.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049869039.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049884899.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049870237.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049880195.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049871163.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880860.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049866611.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876511.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049887668.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_049881076.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049869052.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049878137.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_049866079.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_049872823.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_049888233.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049880705.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879455.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049879226.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049887225.1	9	Reactome: R-HSA-5627083;Reactome: R-HSA-9615710;Reactome: R-HSA-382556;Reactome: R-HSA-9613829;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880	"RHO GTPases regulate CFTR trafficking";"Late endosomal microautophagy";"ABC-family proteins mediated transport";"Chaperone Mediated Autophagy";"Clathrin-mediated endocytosis";"Aggrephagy";"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases"
XP_049867276.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049867516.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049867949.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049872354.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049876248.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049876610.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049874607.1	1	Reactome: R-HSA-419771	"Opsins"
XP_049874265.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049867636.1	3	Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12	"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism"
XP_049876262.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049887933.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049880413.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049868812.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049883805.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049880746.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049884909.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049879294.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049868357.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_049867779.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_049882968.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049884812.1	15	Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-9665247;Reactome: R-HSA-1236382;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565	"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants"
XP_049873298.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate"
XP_049884640.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049883840.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_049869231.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049884358.1	4	MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049872973.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_049866594.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-1250347;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-6811558;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985	"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB4 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4"
XP_049875865.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049873823.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049865813.1	26	Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-69205;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-6804114;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-4615885;Reactome: R-HSA-5696397;Reactome: R-HSA-8866654;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-5651801	"Removal of the Flap Intermediate";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"G1/S-Specific Transcription";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair"
XP_049869712.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049875711.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049868635.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049871441.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_049878649.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049887717.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_049879705.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism"
XP_049874663.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_049881203.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049874805.1	4	Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_049879768.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_049887336.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_049874390.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049879859.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049868750.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864941.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049882107.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_049873172.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_049883343.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837	"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation"
XP_049875982.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049879718.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049886122.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049882939.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049877606.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049882938.1	6	MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)"
XP_049867619.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049881843.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049866790.1	16	Reactome: R-HSA-1810476;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-5603037;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-5602680;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-6811558;Reactome: R-HSA-975138;Reactome: R-HSA-5602498	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR5)";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR2/4)"
XP_049875270.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049878844.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049865907.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049869054.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049886237.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_049870398.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_049887935.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049882211.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049879658.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_049868297.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_049864973.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-195399;Reactome: R-HSA-194313	"Platelet degranulation";"VEGF binds to VEGFR leading to receptor dimerization";"VEGF ligand-receptor interactions"
XP_049880942.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_049871216.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4	"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Synthesis of PA";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism"
XP_049865562.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049878027.1	7	KEGG: 00860+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315	"Porphyrin and chlorophyll metabolism";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol"
XP_049873501.1	29	Reactome: R-HSA-5685942;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-68962;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"HDR through Homologous Recombination (HRR)";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HSF1 activation";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of the pre-replicative complex";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_049865067.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_049865269.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049871599.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049886556.1	40	Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape"
XP_049875786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049872083.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049884483.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873143.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_049879649.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049872940.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049882708.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049881294.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881145.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049882529.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049876149.1	5	Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619	"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN"
XP_049875284.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_049882417.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049880831.1	14	MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1	"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_049873859.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_049865029.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_049873243.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_049886492.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049879565.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_049867843.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049877349.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049876019.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_049882856.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_049873455.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049879224.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049871008.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_049886021.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075	"Dual Incision in GG-NER";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_049884507.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-264870	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049876557.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049873322.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_049878076.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049873875.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049872584.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880742.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049872075.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049868403.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_049880305.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049874589.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_049880534.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049882036.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049864866.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049873762.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049887328.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_049873418.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049865962.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049875290.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_049881549.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_049880240.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-9010553	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs"
XP_049865073.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_049872619.1	9	MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;MetaCyc: PWY-6470;MetaCyc: PWY-6471;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;KEGG: 00510+2.4.1.141	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"N-Glycan biosynthesis"
XP_049884625.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049883621.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049888054.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049878427.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049877325.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049875650.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5620922	"Hedgehog 'off' state";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium"
XP_049878935.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049875918.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049867342.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535;Reactome: R-HSA-916853;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19	"beta-Alanine metabolism";"4-aminobutanoate degradation III";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"Degradation of GABA";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"Propanoate metabolism"
XP_049871442.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity"
XP_049880708.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049866552.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_049883273.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049873699.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_049866330.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049883023.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049877537.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049870400.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049887641.1	7	MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2	"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_049886468.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049873039.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049867927.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049865403.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049872430.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049878914.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948	"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants"
XP_049871240.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049879192.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_049872372.1	8	Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464	"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_049865309.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_049876245.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_049878097.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049864902.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_049865645.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-196025	"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Formation of annular gap junctions"
XP_049877336.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943	"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_049879136.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049866519.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049885153.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049877726.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049879201.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049875086.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049865139.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049867802.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049885600.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049867947.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049883617.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049870256.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction"
XP_049867641.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_049874206.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049869716.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049883504.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_049866842.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049867969.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049886330.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049877803.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049885658.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920	"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability"
XP_049876585.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049866779.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic"
XP_049877409.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049880541.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_049885082.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049879905.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049888013.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_049866843.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_049886445.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049877293.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049866958.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049880000.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049868814.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049882627.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049874352.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049881183.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128	"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling"
XP_049878185.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049870175.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049869715.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049882911.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049872739.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049878318.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049872408.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_049881058.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049887230.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049879688.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Acyl chain remodelling of PC"
XP_049869199.1	8	MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733	"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis"
XP_049866074.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation"
XP_049865452.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174084	"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049882685.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049885700.1	33	Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648	"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049877999.1	11	MetaCyc: PWY-6383;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-6859	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis"
XP_049873944.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_049871741.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880026.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885304.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049885961.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_049872546.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049884835.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049876187.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049880656.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_049885350.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_049867090.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_049868018.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049868996.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880	"EGFR downregulation";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Ub-specific processing proteases"
XP_049879908.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049869347.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049871366.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs"
XP_049875676.1	17	Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-4086398;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-168638	"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"Ca2+ pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway"
XP_049872654.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049884190.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049885583.1	7	MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_049878280.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6807505	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes"
XP_049884647.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049865575.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049875942.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_049873079.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049878813.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_049868632.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_049867942.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049865659.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049886167.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049865811.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049872753.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_049873058.1	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_049879987.1	11	Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression"
XP_049868525.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049882797.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-68827	"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex"
XP_049887504.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049866861.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049881507.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879138.1	12	MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142	"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_049886002.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049873105.1	12	Reactome: R-HSA-1839117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1	"Signaling by cytosolic FGFR1 fusion mutants";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Human papillomavirus infection"
XP_049883835.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049886362.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049869598.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_049872313.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049871575.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049885598.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049879264.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049877448.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_049871528.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049865402.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049868123.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_049868892.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_049872018.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049881861.1	4	Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis"
XP_049877311.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049882586.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287	"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery"
XP_049873421.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049878494.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_049876200.1	18	MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7205	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_049883191.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049879862.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049877333.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049885652.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049869155.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049887824.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2500257	"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events";"RHO GTPases Activate Formins";"Gap junction assembly";"Separation of Sister Chromatids";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion"
XP_049875090.1	16	Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049877138.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049871209.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_049871315.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_049885817.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049869144.1	17	Reactome: R-HSA-2559585;Reactome: R-HSA-6804114;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-69231;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1362300;Reactome: R-HSA-9616222;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-113501;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Oncogene Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin D associated events in G1";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcriptional regulation of granulopoiesis";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"G1/S-Specific Transcription"
XP_049879525.1	6	KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_049884491.1	19	MetaCyc: PWY-7184;MetaCyc: PWY-7221;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7226;Reactome: R-HSA-380270;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Purine metabolism";"UTP and CTP de novo biosynthesis"
XP_049887205.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_049864863.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049866526.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_049887410.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049887740.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049874991.1	9	MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-196780	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Biotin transport and metabolism"
XP_049885494.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049869641.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878	"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport"
XP_049869156.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_049870148.1	13	MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2	"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes"
XP_049882095.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049866000.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049875892.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049869204.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Phytate degradation I";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_049881283.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
YP_010449131.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049877571.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049865626.1	8	Reactome: R-HSA-6791055;Reactome: R-HSA-8950505;Reactome: R-HSA-71336;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2	"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway"
XP_049872081.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049876246.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
YP_010449133.1	7	MetaCyc: PWY-4302;MetaCyc: PWY-5083;MetaCyc: PWY-6692;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-3781	"Aerobic respiration III (alternative oxidase pathway)";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Respiratory electron transport";"Oxidative phosphorylation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)"
XP_049882507.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049872828.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049866858.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049881590.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_049883295.1	7	Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation"
XP_049868675.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049886240.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049878109.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049877672.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750;Reactome: R-HSA-69202	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition"
XP_049877314.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049876036.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049879216.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049884369.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049866527.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-111932	"RAF activation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB"
XP_049878278.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049873106.1	12	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-1839117;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"NRAGE signals death through JNK";"Signaling by cytosolic FGFR1 fusion mutants";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Human cytomegalovirus infection"
XP_049868904.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049865291.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296	"CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome"
XP_049872441.1	5	Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_049878901.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism"
XP_049877759.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049877372.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049878932.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049868530.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049879468.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049883300.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598	"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"
XP_049873145.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_049874050.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885	"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins"
XP_049870667.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_049879597.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_049885015.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049868768.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049870815.1	8	KEGG: 00380+3.5.1.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7717;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-7734	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis"
XP_049868677.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_049884665.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049877394.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049882972.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049885151.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049876181.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_049873912.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049866405.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049871311.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_049865623.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049870333.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7218;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003	"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Glycerol degradation to butanol"
XP_049887636.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049867035.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049884451.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049872240.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049882583.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_049877895.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_049883097.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049872489.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049882563.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049866077.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_049878317.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049879124.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049880126.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-3821	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification"
XP_049879968.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049871609.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_049871411.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049866946.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049869843.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_049871608.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049881035.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049882419.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049873257.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_049876764.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_049887461.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049877852.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_049877403.1	4	KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol"
XP_049887188.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049875799.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049869387.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049871790.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049882424.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049882530.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049878428.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867936.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation"
XP_049878108.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049881185.1	57	Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-68827	"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex"
XP_049871448.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049874419.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049873138.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_049866938.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_049883863.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049881309.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049874579.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870	"Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_049871888.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state";"Activation of SMO"
XP_049874611.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_049878738.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049876134.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_049874569.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049868472.1	17	MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7210	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_049878116.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_049872041.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049874012.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_049869677.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_049885149.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049869399.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049864950.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049865383.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94	"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"N-Glycan biosynthesis"
XP_049866331.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_049873034.1	16	Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-196025;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-8964038	"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions";"VLDLR internalisation and degradation";"Recycling pathway of L1";"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance"
XP_049878377.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism"
XP_049883177.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049878496.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049867784.1	12	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049866857.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049873835.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049867992.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049865894.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_049885823.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049886277.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049876327.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049869965.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle"
XP_049871116.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_049885609.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049864862.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049865777.1	14	MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_049875208.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-375276	"G alpha (s) signalling events";"Peptide ligand-binding receptors"
XP_049870138.1	4	Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus"
XP_049873887.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049879368.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_049868969.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580	"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence"
XP_049882228.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049884967.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049874990.1	9	Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086	"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_049874324.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049872685.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869429.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049886234.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049873586.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_049880818.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049877093.1	3	KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685	"Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species"
XP_049869335.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling"
XP_049885150.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049883539.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_049883925.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049878234.1	8	Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269	"Synthesis of PG";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II"
XP_049881257.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049867076.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049882711.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049874022.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764	"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination"
XP_049867105.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_049881209.1	40	Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-72165	"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway"
XP_049867787.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049887880.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148	"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049886124.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_049869805.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049867438.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_049881817.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_049887195.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_049877716.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049878124.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_049868702.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049878693.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180746	"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein"
XP_049888170.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_049876378.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_049879296.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"Macroautophagy";"Intraflagellar transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion"
XP_049883043.1	42	Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-427389;Reactome: R-HSA-912446;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-9610379;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-8939236;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638	"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"HCMV Late Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins"
XP_049878057.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257	"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion"
XP_049864858.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049880214.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049866422.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049867864.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049886213.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049871728.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879795.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049869938.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_049873275.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049870399.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_049867144.1	7	MetaCyc: PWY-5698;MetaCyc: PWY-5686;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis I";"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_049873516.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_049876665.1	2	Reactome: R-HSA-177135;Reactome: R-HSA-177128	"Conjugation of benzoate with glycine";"Conjugation of salicylate with glycine"
XP_049879978.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_049869690.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049885811.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049884710.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558	"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_049876742.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049873867.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_049880842.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040	"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis"
XP_049885632.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049872428.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049879823.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049875033.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049867458.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_049878560.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049885657.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049872487.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_049869046.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049886772.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_049874585.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049880271.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049869000.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971	"Ub-specific processing proteases";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation"
XP_049869966.1	9	MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7902	"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glucosylglycerol biosynthesis"
XP_049883615.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049877076.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049872830.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_049881374.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049884802.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_049864972.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_049873801.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049885822.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049869074.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_049885944.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049867951.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049871891.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5620922	"Hedgehog 'on' state";"Hedgehog 'off' state";"Activation of SMO";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium"
XP_049884995.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049873676.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049884653.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049878941.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049869612.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049878014.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049869819.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_049877825.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049866624.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049881910.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling"
XP_049867662.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049875006.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049886157.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049880202.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_049866335.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049868098.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049865665.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883020.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049876493.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049878997.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_049877671.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_049870355.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049883601.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049873585.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049868833.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490	"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation"
XP_049881289.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_049886418.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049874286.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049878226.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_049873445.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049887765.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_049880552.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049879406.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049866954.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049866937.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_049877078.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_049872494.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049874922.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684	"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Hedgehog 'on' state"
XP_049866736.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049865026.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049872605.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049874384.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_049866677.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049879185.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_049867466.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049884645.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049885818.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_049865129.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_049876088.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049865373.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049876421.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049874157.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049884682.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049867197.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
XP_049871603.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_049872267.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_049886071.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_049871798.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049868887.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049888015.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-170822	"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_049872090.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049881144.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049878323.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049882063.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049865773.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049868275.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_049883935.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049869004.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Ub-specific processing proteases";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_049883026.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049869256.1	25	Reactome: R-HSA-163359;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-381771;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events"
XP_049875783.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049878847.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049882855.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_049875688.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Insulin receptor recycling"
XP_049874621.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049870625.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system"
XP_049869536.1	9	KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II"
XP_049869248.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_049865639.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049877669.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_049872555.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049877335.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_049888118.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_049875718.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049870648.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049872495.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882584.1	8	Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524	"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)"
XP_049871602.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_049873652.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049884105.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049870787.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_049876132.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049884145.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049865270.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049869136.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049881569.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049878828.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_049865122.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049869741.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_049868856.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049879884.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049882593.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_049887655.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049880404.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049869425.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049881344.1	5	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_049888240.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049878355.1	12	Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856	"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_049881124.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049876957.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism"
XP_049885667.1	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6351	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_049884258.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049874449.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049882429.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883629.1	17	KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780	"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism"
XP_049866689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049870025.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049883627.1	17	KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722	"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis"
XP_049879049.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049872432.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886	"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HDMs demethylate histones";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_049869825.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049877969.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049878397.1	7	MetaCyc: PWY-7854;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-7118;MetaCyc: PWY-7295	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Pyruvate metabolism";"D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"L-arabinose degradation IV"
XP_049870837.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_049867394.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049868661.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049877795.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_049874678.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049877408.1	4	MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72	"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis"
XP_049867624.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049884499.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049884423.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049870587.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873650.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2"
XP_049866224.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049882294.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049876094.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint"
XP_049880814.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049881589.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-139853	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels"
XP_049868786.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049868391.1	15	Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-1257604	"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"PIP3 activates AKT signaling"
XP_049887259.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049876953.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049868796.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_049870464.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7663	"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Biotin metabolism";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)"
XP_049886343.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049869329.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881069.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049882997.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_049867311.1	8	Reactome: R-HSA-70635;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-4984;KEGG: 00220+4.3.2.1	"Urea cycle";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Arginine biosynthesis"
XP_049865401.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049879288.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway"
XP_049872513.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_049885281.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-193648	"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"NRAGE signals death through JNK"
XP_049874549.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_049874921.1	1	Reactome: R-HSA-156581	"Methylation"
XP_049883734.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049865257.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_049880036.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320	"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Gap junction assembly";"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes"
XP_049874144.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049871813.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049867377.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins"
XP_049884854.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049871444.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_049886284.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049885181.1	12	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"DCC mediated attractive signaling";"NRAGE signals death through JNK";"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Human cytomegalovirus infection"
XP_049879517.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049881728.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_049873238.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_049887084.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_049877707.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_049876995.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_049878838.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049874378.1	31	MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-8012;Reactome: R-HSA-199220;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5147	"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Fatty acid biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)"
XP_049865204.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049868832.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_049875859.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_049869845.1	5	Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189	"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_049876496.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049870216.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049881745.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_049881846.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364	"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049886753.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_049873555.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049867485.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049874969.1	8	Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Photosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"Insulin receptor recycling"
XP_049885734.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_049876138.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_049868502.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049884260.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;Reactome: R-HSA-1268020;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5872	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_049872881.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_049876219.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049877242.1	5	Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-936964	"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049887583.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049868862.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049868583.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049865812.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_049872039.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049869340.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_049865568.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_049869554.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_049868328.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049870112.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex"
XP_049871890.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922	"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium"
XP_049887258.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_049864945.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049878119.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049885752.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049876379.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_049866658.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049886190.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049873872.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049882525.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873029.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049882271.1	4	MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_049877541.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049879840.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049887645.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049866855.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049881604.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049879779.1	11	KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2	"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_049879640.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_049879410.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887387.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049884976.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049882475.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049865389.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_049885264.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_049873671.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049884989.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049887465.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_049873874.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049871447.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049873529.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_049866385.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049871619.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049868594.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049872534.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_049867084.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_049880035.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-437239	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases Activate Formins";"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recycling pathway of L1"
XP_049874801.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_049879197.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_049877921.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049866426.1	7	KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_049865380.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378	"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling"
XP_049865760.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049866593.1	16	Reactome: R-HSA-1250342;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1963640	"PI3K events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling"
XP_049866213.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_049883899.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_049884853.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049882006.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_049869215.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049877605.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_049872316.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_049866442.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_049879325.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049885553.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049887865.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049865761.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049871980.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049873290.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049887732.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049872539.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-525793	"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis"
XP_049866166.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_049876561.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049875012.1	9	Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"G alpha (q) signalling events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_049872655.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049881255.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049875972.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049867073.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049873422.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049865490.1	1	Reactome: R-HSA-1614603	"Cysteine formation from homocysteine"
XP_049878817.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_049884104.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049872184.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049880740.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049883168.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049883493.1	13	KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7112;MetaCyc: PWY-2261;Reactome: R-HSA-196836;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1	"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism"
XP_049874785.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_049882544.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022538	"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA"
XP_049867785.1	12	Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038	"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions"
XP_049884654.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049883648.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049877758.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049885973.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049885340.1	8	MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Cysteine and methionine metabolism"
XP_049864979.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7849;MetaCyc: PWY-7394	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Urate conversion to allantoin II"
XP_049869685.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049885219.1	6	Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_049870401.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_049879101.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_049879799.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_049883156.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_049871467.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049868958.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049866626.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_049879342.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049880208.1	56	Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541	"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway"
XP_049880008.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049884524.1	6	MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530	"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II"
XP_049866619.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049880252.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_049871155.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_049870469.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_049883630.1	17	KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722	"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis"
XP_049880506.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049879745.1	11	KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism"
XP_049872201.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049882510.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049887534.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_049866518.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049880646.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049871004.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049888052.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_049874024.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049866608.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_049887009.1	15	Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174178	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049876560.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049878265.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049882421.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049886282.1	8	MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5394;MetaCyc: PWY-3581;MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2	"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis I";"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"Tyrosine metabolism"
XP_049883401.1	12	MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;MetaCyc: PWY-5857	"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)"
XP_049873605.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049866424.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049870139.1	4	Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017	"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_049873873.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049882166.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_049878930.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_049865764.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_049867404.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049874205.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049882512.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879763.1	11	MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_049872517.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_049886091.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049870336.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003	"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Purine metabolism";"Glycerol degradation to butanol"
XP_049868171.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049880319.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049878887.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_049869073.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049869479.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_049865743.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049882276.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_049883542.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049868125.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_049884080.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism"
XP_049867888.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_049865598.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_049884846.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049882571.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049885684.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_049873353.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049866567.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049879919.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)"
XP_049865384.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049866770.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1592389	"Neutrophil degranulation";"Activation of Matrix Metalloproteinases"
XP_049870950.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_049883376.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049885629.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049871462.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049867294.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs"
XP_049869034.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_049874846.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_049865405.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049865918.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049885903.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_049886370.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049881375.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049864890.1	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_049883079.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049873943.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049869312.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882	"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_049885887.1	10	MetaCyc: PWY-6901;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-6886;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003	"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol"
XP_049868976.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049871976.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049875866.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_049865216.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049887695.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049887277.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_049885819.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049876792.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049875362.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_049870028.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049871458.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049872015.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049875906.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049883838.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_049866786.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-879415;Reactome: R-HSA-6798695	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation"
XP_049877482.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_049864846.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049870948.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049886295.1	4	MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614	"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_049873332.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049882713.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_049879691.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_049885084.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049869711.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049872781.1	6	MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165	"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_049878120.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049872529.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049865406.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_049884156.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_049869336.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_049880741.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049885686.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_049875952.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049878122.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_049879470.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_049874636.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049868290.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_049870029.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_049872072.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049871930.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-77387	"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling"
XP_049866389.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049878978.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_049876453.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288	"MAP2K and MAPK activation";"mTORC1-mediated signalling";"mTOR signalling";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1"
XP_049888094.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049883297.1	7	Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201	"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis"
XP_049873536.1	3	Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999	"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_049879781.1	11	MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+6.3.5.5	"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism"
XP_049880521.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049880959.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049885628.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049880665.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049869474.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049876040.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049870203.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion"
XP_049881873.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049876899.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_049870119.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866902.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_049866320.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049880554.1	1	Reactome: R-HSA-6805567	"Keratinization"
XP_049865229.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049880453.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_049880370.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049879690.1	8	MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1	"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage III";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine deoxyribonucleosides degradation II"
XP_049879542.1	19	KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115	"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"Methylaspartate cycle";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049866837.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091	"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells"
XP_049886299.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049878910.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_049878920.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049870194.1	13	MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle"
XP_049868619.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049884969.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049876528.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049877729.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049870608.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049879760.1	11	KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_049877441.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_049869396.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049887130.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049884481.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049871454.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049879415.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049873803.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_049868521.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049881695.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_049877989.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_049887836.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049867107.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049885154.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049869377.1	31	MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5142	"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway"
XP_049887029.1	6	Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions"
XP_049887222.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049887741.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049877139.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_049885545.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049871624.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049867407.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585	"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G"
XP_049872071.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049869634.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport"
XP_049872463.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049877845.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_049886590.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_049883167.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270	"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes"
XP_049865182.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049881596.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049865783.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_049883951.1	26	Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-381340	"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_049868279.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877153.1	13	KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52	"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation"
XP_049869139.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_049880638.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049865646.1	8	Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_049883999.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049882077.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_049885534.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049869070.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049868638.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049874809.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_049888230.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049866443.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_049880666.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879499.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage III";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism"
XP_049883078.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049873419.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049880847.1	5	KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4	"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Geraniol degradation"
XP_049866682.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049872088.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049879260.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049877345.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049870379.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049870438.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;MetaCyc: PWY-6898	"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III"
XP_049885091.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049884782.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049865897.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049881269.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_049877084.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049883112.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049872311.1	8	KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_049880168.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex"
XP_049874848.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_049875620.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_049868593.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_049869120.1	7	MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis I"
XP_049880341.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049887066.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049887437.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_049870845.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle"
XP_049866766.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_049877247.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_049887158.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_049867995.1	14	KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-399997;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418217	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta"
XP_049883619.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049887736.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866648.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_049884889.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049887433.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_049875807.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_049876734.1	15	Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_049876038.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049865775.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049869514.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_049874314.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049874988.1	9	Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1	"Biotin transport and metabolism";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes"
XP_049873354.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_049879493.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049887426.1	5	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Purine metabolism"
XP_049867515.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_049879069.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_049868585.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-9609523;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPI-mediated anterograde transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_049885951.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_049871166.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178	"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_049887807.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049873765.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2"
XP_049886309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049885256.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049881300.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049887412.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049875278.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_049866276.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6	"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism"
XP_049867001.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_049878019.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049884121.1	6	KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;MetaCyc: PWY-7927;Reactome: R-HSA-69273;Reactome: R-HSA-8862803;Reactome: R-HSA-1614558	"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)";"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Degradation of cysteine and homocysteine"
XP_049880945.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049869441.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_049882125.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049880415.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989	"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_049865796.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049887360.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049884486.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049871540.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049876970.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615	"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation"
XP_049869626.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049872026.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049871700.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_049887595.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049869356.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_049876657.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049871425.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_049881848.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_049868581.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_049866620.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049865037.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049866241.1	21	MetaCyc: PWY-7219;MetaCyc: PWY-7226;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7205	"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_049872007.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049873200.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_049870531.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049876617.1	6	Reactome: R-HSA-8949613;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020	"Cristae formation";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import"
XP_049864885.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049875009.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049881660.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049880493.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049867790.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049883169.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_049872464.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_049877864.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049867388.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049865958.1	5	MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695	"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation"
XP_049873936.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049876603.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049876555.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049872938.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049883543.1	52	Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-5617472;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-76066;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049874174.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049874361.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049881459.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1"
XP_049867456.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049875610.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection"
XP_049885637.1	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343	"Galactose metabolism";"Stachyose degradation";"Glycogen synthesis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I"
XP_049880636.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_049879160.1	4	KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841	"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_049883523.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049877407.1	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;MetaCyc: PWY-8026	"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)"
XP_049883190.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049871491.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_049879764.1	11	MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2	"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism"
XP_049884970.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049882802.1	4	KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;KEGG: 00500+3.1.3.9;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Gluconeogenesis"
XP_049874376.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5971;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7663	"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Biotin metabolism";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)"
XP_049888178.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_049875140.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424	"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling"
XP_049865140.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_049869125.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236	"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049885533.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049875100.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880533.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049873654.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1	"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection"
XP_049864939.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_049868501.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049872095.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049874702.1	5	Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of AXIN"
XP_049874582.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049875078.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_049873871.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049877280.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049865051.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049876966.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
XP_049874013.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_049881497.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049885920.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_049875980.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049885224.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_049886242.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_049885599.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_049869633.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257	"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion"
XP_049885535.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_049884884.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry"
XP_049869656.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_049866904.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049868820.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_049870916.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures"
XP_049887354.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695	"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation"
XP_049877318.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628	"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_049866907.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_049874191.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_049877346.1	6	Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049877228.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_049875301.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049865047.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049883821.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_049874762.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049879490.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049866390.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_049885139.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049872286.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits"
XP_049872323.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_049884845.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049885501.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_049883600.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887463.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_049882625.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049869393.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049873221.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_049866632.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_049874821.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049877406.1	4	KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;Reactome: R-HSA-6807047;MetaCyc: PWY-8026	"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)"
XP_049869522.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_049871871.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049871979.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049874363.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_049884108.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_049871490.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_049872342.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049879238.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049867638.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049877498.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_049866543.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_049885245.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049887683.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_049886104.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049880495.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_049878744.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_049878934.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_049873006.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049873806.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277	"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex"
XP_049868885.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049869311.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_049885649.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_049874677.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_049867468.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049874195.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_049880967.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049865552.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049868875.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_049879837.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_049872255.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-176187	"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Activation of ATR in response to replication stress"
XP_049879663.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_049886090.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy"
XP_049882418.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_049868009.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049880047.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049877396.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049887900.1	3	MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117	"Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I"
XP_049881594.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049882766.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_049867074.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_049879210.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-6113;Reactome: R-HSA-75105;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7663	"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Fatty acid biosynthesis";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)"
XP_049875146.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5740;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-5739	"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis"
XP_049876843.1	17	KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167290;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167238;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167246	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"T cell receptor signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript"
XP_049883626.1	17	MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2	"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_049867997.1	14	Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-399997;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-7039	"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_049866573.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049866955.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049865762.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_049874583.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049886361.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049881043.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049871461.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_049872373.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111463	"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs"
XP_049878101.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049886037.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_049881890.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5663220	"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recycling pathway of L1";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Aggrephagy";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"RHO GTPases Activate Formins"
XP_049874733.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049875246.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_049877744.1	4	Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_049881608.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049870636.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_049869196.1	8	MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7733	"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism";"3-hydroxyquinaldate biosynthesis"
XP_049887902.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_049864944.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049881509.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049874027.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_049869369.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049883953.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-977225	"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Amyloid fiber formation"
XP_049871753.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane"
XP_049869722.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049867274.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049864877.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049866673.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049877143.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049871917.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_049868884.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049885509.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_049883173.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270	"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes"
XP_049870875.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049880499.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_049878325.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049884954.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049887552.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_049872207.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049884512.1	7	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_049885215.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_049869587.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049874145.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049875545.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049866646.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049879873.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049867856.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_049877150.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_049876163.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049883632.1	17	MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis"
XP_049883428.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_049867397.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049880644.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049871537.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity"
XP_049872835.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation"
XP_049875700.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_049866691.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049880227.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_049887947.1	4	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation"
XP_049868963.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_049870545.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519	"Attenuation phase";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression"
YP_010449128.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_049866711.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049871009.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_049866400.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_049870255.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_049883011.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049884827.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_049867858.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_049866321.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049880700.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_049879114.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_049880761.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_049873080.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049882177.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_049870467.1	4	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_049874225.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049868390.1	15	Reactome: R-HSA-1433557;Reactome: R-HSA-9009391;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-114604	"Signaling by SCF-KIT";"Extra-nuclear estrogen signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"RET signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade"
XP_049870158.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_049872374.1	8	Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111459	"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage"
XP_049868458.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049874116.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_049887888.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_049866313.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_049878299.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_049877272.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7721;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-5123	"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_049870594.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049880919.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049876604.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049881370.1	7	MetaCyc: PWY-8004;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Pentose phosphate pathway";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049880963.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049877032.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_049884225.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_049885567.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049870331.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049865181.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049887634.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-201722	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex"
XP_049874904.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_049879172.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049875067.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049883016.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049872074.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_049874522.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_049877538.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049877610.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684	"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism"
XP_049888130.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049870807.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_049881225.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_049884036.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_049873291.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049876996.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events"
XP_049883369.1	7	KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403	"Lysine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)"
XP_049870453.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_049881988.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049869881.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049872375.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458	"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome"
XP_049870431.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049871622.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_049877500.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_049872426.1	10	KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis"
XP_049884912.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_049884478.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049873877.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_049870599.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049886707.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_049864957.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_049873578.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_049885341.1	8	MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis"
XP_049876212.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_049865235.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_049884896.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049880100.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis"
XP_049878180.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5658442	"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Hedgehog 'on' state";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Neddylation";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Regulation of RAS by GAPs"
XP_049884479.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049874834.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049885938.1	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_049879893.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049881613.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049870125.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867	"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex"
XP_049866226.1	5	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_049876658.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_049880306.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049872434.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_049865662.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_049882689.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049880743.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049887928.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049872855.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_049875970.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_049884228.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049886366.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049877727.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049883623.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_049868026.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049876972.1	34	Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-9639288;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813	"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Amino acids regulate mTORC1";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids"
XP_049880737.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_049872925.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_049880367.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585	"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"G2/M Checkpoints";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G"
XP_049875646.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_049875001.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_049884907.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (i) signalling events"
XP_049874830.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049876605.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_049869223.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_049876026.1	4	MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_049885576.1	7	MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
XP_049884904.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_049875975.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049887526.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_049883166.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition"
XP_049874578.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049887742.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049866532.1	11	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049885044.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_049873558.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_049878414.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_049865222.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049881033.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049874923.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049870876.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_049878453.1	7	KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_049880471.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049866377.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_049879708.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism"
XP_049885634.1	12	KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527	"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Galactose metabolism";"Glycerolipid metabolism";"Glycogen synthesis";"Stachyose degradation"
XP_049880712.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049866572.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_049870937.1	8	Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Signaling by Hippo";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_049867866.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_049873539.1	5	MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate"
XP_049868022.1	13	KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)"
XP_049878733.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_049871421.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049875320.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_049884229.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049879270.1	10	MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895	"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis"
XP_049867040.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049883694.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049883834.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_049886437.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191	"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Synthesis of PC"
XP_049883759.1	3	Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067	"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_049867786.1	12	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-438066	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_049874952.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049881729.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_049876265.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_049884874.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation"
XP_049865120.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049865886.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049867452.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-5136	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_049869723.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049883104.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049880196.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049870440.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6908	"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)"
XP_049883736.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049872226.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_049882585.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_049875788.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887320.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049884649.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049881338.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_049881364.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049882706.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_049869301.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_049880205.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_049879165.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_049883923.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399	"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy"
XP_049884920.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_049873387.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6837	"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_049876150.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367	"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines"
XP_049866725.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049872285.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_049866232.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049872079.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049879803.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_049875069.1	1	Reactome: R-HSA-975578	"Reactions specific to the complex N-glycan synthesis pathway"
XP_049879762.1	11	KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753	"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis"
XP_049877912.1	8	Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083633	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_049874618.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_049882572.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_049884783.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_049868998.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-5689880	"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases"
XP_049879469.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_049871502.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049866369.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049881892.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-983189	"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"HCMV Early Events";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Gap junction assembly";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Kinesins"
XP_049874545.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_049877395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049883760.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_049885625.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049869275.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_049866332.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_049872518.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_049872583.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049878703.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049868269.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049870967.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_049876503.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049865908.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_049887929.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_049874938.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049883373.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4	"Linoleic acid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism"
XP_049870120.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049882523.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049869570.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_049880958.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_049884975.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_049867406.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_049887895.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_049885615.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049879707.1	5	MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3	"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism"
XP_049864881.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049876559.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_049881323.1	5	KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation"
XP_049875366.1	13	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6728	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle"
XP_049877494.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049867862.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_049868704.1	5	KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185	"Purine metabolism";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I"
XP_049872414.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_049881602.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049864994.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination"
XP_049874839.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_049866610.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_049868523.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_049880373.1	22	MetaCyc: PWY-5514;MetaCyc: PWY-6981;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-7385;KEGG: 00010+5.3.1.9;Reactome: R-HSA-70171;MetaCyc: PWY-8013;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-6992;MetaCyc: PWY-622;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-5054;MetaCyc: PWY-621;MetaCyc: PWY-5659	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"1,5-anhydrofructose degradation";"Starch biosynthesis";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"GDP-mannose biosynthesis"
XP_049884897.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_049886081.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049875244.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049885176.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_049877799.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_049881588.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-983695	"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_049888093.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049877699.1	4	Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism"
XP_049867791.1	8	Reactome: R-HSA-9609736;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982	"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_049877829.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression"
XP_049881470.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_049865883.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_049865127.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_049871313.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_049871276.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_049885565.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_049880246.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706	"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049865871.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_049878644.1	7	Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_049883789.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_049886162.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049881396.1	7	MetaCyc: PWY-7805;MetaCyc: PWY-6610;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;Reactome: R-HSA-74217	"(aminomethyl)phosphonate degradation";"Adenine salvage";"Adenine and adenosine salvage II";"Purine metabolism";"Glyphosate degradation III";"Neutrophil degranulation";"Purine salvage"
XP_049868908.1	6	MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Synthesis of PG"
XP_049879867.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049868435.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049873404.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_049887226.1	9	Reactome: R-HSA-8856825;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-8856828;Reactome: R-HSA-9613829;Reactome: R-HSA-5689880;Reactome: R-HSA-9615710;Reactome: R-HSA-5627083;Reactome: R-HSA-382556	"Cargo recognition for clathrin-mediated endocytosis";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"Clathrin-mediated endocytosis";"Chaperone Mediated Autophagy";"Ub-specific processing proteases";"Late endosomal microautophagy";"RHO GTPases regulate CFTR trafficking";"ABC-family proteins mediated transport"
XP_049878875.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis"
XP_049874680.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_049870441.1	6	Reactome: R-HSA-196819;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908	"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)"
XP_049867414.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_049884287.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_049865809.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_049883347.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049876483.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049868338.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049879927.1	5	Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_049869255.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-192823	"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation"
XP_049872416.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_049871177.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_049878241.1	13	Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745	"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_049876269.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_049875516.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_049872784.1	6	MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Ascorbate and aldarate metabolism"
XP_049874411.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049865446.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_049867476.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049866176.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049875679.1	14	MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
XP_049883730.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_049874094.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237	"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2"
XP_049878121.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_049864861.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049870003.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_049873272.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049885946.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049879960.1	2	Reactome: R-HSA-3000178;MetaCyc: PWY-7511	"ECM proteoglycans";"Protein ubiquitination"
XP_049870096.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049886112.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_049879767.1	11	KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-7790	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II"
XP_049882996.1	42	Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-8939236	"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Meiotic synapsis";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"HATs acetylate histones";"HCMV Late Events";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_049876258.1	58	Reactome: R-HSA-5687128;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-5689901;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-180585	"MAPK6/MAPK4 signaling";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Interleukin-1 signaling";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Metalloprotease DUBs";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G"
XP_049875677.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_049885868.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049867333.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_049874152.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_049871291.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_049878357.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_049881762.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_049880561.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_049865399.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_049883094.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049884473.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049883642.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049881031.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049868337.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_049869502.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_049876264.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_049879564.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_049869639.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_049885119.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049887494.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_049867032.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049886105.1	52	Reactome: R-HSA-203927;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167287;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73779	"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_049874558.1	11	Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565	"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_049865211.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18	"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_049875832.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_049865223.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_049876072.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049865046.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049871605.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes"
XP_049872449.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_049876470.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_049875648.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922	"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'on' state";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium"
XP_049872630.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_049868813.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_049873442.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_049881468.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049878328.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_049885824.1	6	KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_049879755.1	11	KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400;Reactome: R-HSA-500753	"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis"
XP_049884366.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_049869832.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_049885004.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049886187.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049870588.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_049888172.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_049870564.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_049882165.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_049873770.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_049867442.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_049874397.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-174084	"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Neddylation";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_049868016.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049879513.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Sialic acid metabolism";"Neutrophil degranulation"
XP_049864884.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_049873446.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7854	"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_049888235.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_049870188.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_049876774.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_049876286.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_049880184.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8852276;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258	"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Degradation of AXIN";"Interleukin-1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Neddylation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL"
XP_049877363.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_049873182.1	13	Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-8943724	"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"mTOR signalling";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription"
XP_049878704.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049879516.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_049873825.1	25	Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-8955332	"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Aggrephagy";"Kinesins";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases Activate Formins";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin"
XP_049876925.1	13	KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation"
XP_049878858.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-7746;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-6519;MetaCyc: PWY-5147;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-5994;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7388;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8049	"Petroselinate biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"ChREBP activates metabolic gene expression";"Pederin biosynthesis"
XP_049865795.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis"
XP_049883371.1	7	MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00020+2.3.1.61	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Lysine catabolism";"Citrate cycle (TCA cycle)"
XP_049871460.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_049879213.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_049881109.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits"
XP_049885076.1	13	MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-6367	"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"DAP12 signaling";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism"
XP_049880734.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_049865117.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_049884519.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001	"Neutrophil degranulation";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade"
XP_049875787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049888048.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049870570.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-7115	"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_049872078.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_049874737.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_049866695.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049877878.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049869678.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_049879263.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_049872419.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_049878107.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_049883041.1	42	Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-1221632;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-9610379;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-212300;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-171306	"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Meiotic recombination";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"DNA methylation";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Meiotic synapsis";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Late Events";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"PRC2 methylates histones and DNA";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends"
XP_049874253.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_049887878.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049865759.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_049877596.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_049869430.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_049871015.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049872599.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_049886074.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_049880820.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_049875714.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049866773.1	2	Reactome: R-HSA-1592389;Reactome: R-HSA-6798695	"Activation of Matrix Metalloproteinases";"Neutrophil degranulation"
XP_049870494.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA"
XP_049887244.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_049885940.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_049885745.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049873136.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_049877708.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_049878707.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_049874935.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_049866383.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_049868017.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_049881931.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_049881304.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049884703.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_049882684.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049877515.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408	"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation"
XP_049872057.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_049885155.1	7	KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_049866747.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_049866401.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_049871757.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_049866090.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_049885546.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_049868444.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049879937.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_049880229.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_049876765.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049867690.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_049883561.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049867659.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_049876162.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_049879297.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Intraflagellar transport";"Macroautophagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049885537.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_049865632.1	10	MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7210;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_049870098.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_049867707.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_049886834.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453	"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response"
XP_049869327.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_049867551.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_049868417.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_049879860.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_049873147.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_049883930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049879947.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_049880054.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_049867881.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_049874524.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_049881342.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_049876028.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_049887581.1	5	KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88	"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism"
XP_049887076.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_049869268.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_049885167.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway"
XP_049882559.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049878252.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049874194.1	13	MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation"
XP_049869592.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_049878079.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049872840.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049882688.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_049881458.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_049874163.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049881262.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_049872415.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_049885660.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_049885032.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_049887299.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049872485.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049869842.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_049880987.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_049873802.1	3	Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3	"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_049866153.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049885345.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_049885608.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_049872238.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_049874186.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_049887602.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_049882001.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_049865910.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_049879789.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression"
XP_049877469.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049875291.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-6799;MetaCyc: PWY-6519;MetaCyc: PWY-4381;MetaCyc: PWY-5971;MetaCyc: PWY-7664;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-8047;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWYG-321;MetaCyc: PWY-7388;MetaCyc: PWY-5366;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8049;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-7663	"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"Fatty acid biosynthesis";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Gondoate biosynthesis (anaerobic)"
XP_049873907.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_049866365.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_049877513.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723	"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation"
XP_049884235.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-190840	"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"HCMV Early Events";"Gap junction assembly";"RHO GTPases Activate Formins";"Cilium Assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_049882400.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_049883510.1	42	Reactome: R-HSA-2559582;Reactome: R-HSA-9616222;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-5250924;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-110328;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-73728;Reactome: R-HSA-5578749;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-2559586;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-427389;Reactome: R-HSA-912446	"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation of granulopoiesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"HATs acetylate histones";"HCMV Late Events";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"B-WICH complex positively regulates rRNA expression";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDACs deacetylate histones";"Meiotic synapsis";"RMTs methylate histone arginines";"DNA methylation";"RNA Polymerase I Promoter Opening";"Transcriptional regulation by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"DNA Damage/Telomere Stress Induced Senescence";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic recombination"
XP_049868013.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_049876740.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7721;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7709	"Viridicatumtoxin biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis"
XP_049872106.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_049880210.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
XP_049871805.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation"
XP_049878714.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_049865671.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_049881508.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_049876580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_049875400.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_049883066.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-171306	"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends"
XP_049875978.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_049872155.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_049872429.1	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;Reactome: R-HSA-437239	"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1"
XP_049866145.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_049870573.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_049868361.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_049880188.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_049883684.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_049875716.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049880500.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_049876663.1	2	Reactome: R-HSA-177128;Reactome: R-HSA-177135	"Conjugation of salicylate with glycine";"Conjugation of benzoate with glycine"
XP_049876041.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_049877823.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_049877721.1	13	MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-6613;MetaCyc: PWY-7909	"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)"
XP_049885624.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_049883956.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_049886216.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_049865075.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Triglyceride biosynthesis"
XP_049865114.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-201722;Reactome: R-HSA-2644606	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_049879482.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_049869737.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_049868038.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation"
XP_049878506.1	5	Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_049880540.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_049888142.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_049885366.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_049878388.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_049877446.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_049865805.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_049874920.1	10	KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661	"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_049881792.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_049867614.1	11	MetaCyc: PWY-7268;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)"
XP_049877438.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"