Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_037269465.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_037275547.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037282086.1 1 MetaCyc: PWY-7883 "Anhydromuropeptides recycling II" XP_037287741.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037290258.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037281926.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037286267.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037275699.1 12 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Ether lipid metabolism" XP_037276945.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037281992.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037280790.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_037292083.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037281124.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037292180.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037277894.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037281499.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037272888.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037282538.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037284478.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_037269164.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037276645.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037284870.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037272952.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037282397.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling" XP_037291281.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037268375.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Insulin receptor recycling" XP_037288617.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-977225 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation" XP_037283884.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_037286731.1 4 MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_037274734.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_037284673.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037279857.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_037269115.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_037274135.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037286395.1 2 KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" XP_037280603.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606 "Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037283105.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037278216.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037270073.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_037284745.1 5 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_037288385.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037284629.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037278993.1 8 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "ATP biosynthesis";"Photosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_037272205.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037271911.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037271225.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037285325.1 13 Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822 "Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)" XP_037280569.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037289363.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037271800.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037288987.1 6 KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807 "Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_037278750.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_037283345.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037275858.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037287299.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037274145.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_037290755.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037272180.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins" XP_037283486.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037278398.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037277232.1 10 Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-6901 "Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation" XP_037274162.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_037281885.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"mTOR signaling pathway" XP_037291815.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037289164.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037272368.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_037289214.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037274339.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037270623.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037283211.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269702.1 20 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-69091 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Polymerase switching" XP_037280290.1 15 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-912446 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Meiotic recombination" XP_037281298.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037289333.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037279105.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037286914.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037284339.1 7 MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism" XP_037287407.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_037285936.1 20 KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V" XP_037278817.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037271234.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_037276505.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037274857.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037289714.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037269541.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_037268132.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037281874.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037282865.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037279351.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037277065.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_037269456.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037291822.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037268818.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037276222.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"mTOR signalling" XP_037288317.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037284713.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037284708.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_037278496.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037281881.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269829.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037285887.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268329.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037269163.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037292004.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037278945.1 9 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection" XP_037275244.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_037280451.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_037276938.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037274106.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037283121.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037287172.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_037274240.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037274384.1 5 Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037283142.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037274539.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037283715.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037280326.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277227.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_037274518.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037271668.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_037292143.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037289209.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037290009.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_037279346.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037275956.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037288306.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-202733 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Retinoid metabolism and transport";"Chylomicron clearance";"LDL remodeling";"Chylomicron assembly";"VLDL clearance";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL assembly";"Cell surface interactions at the vascular wall" XP_037287554.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037282789.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037281292.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037279262.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037278442.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037283675.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_037274843.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037287556.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_037269021.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037285227.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_037270447.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289716.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037281046.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037285266.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037276607.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_037271353.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_037290498.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037282791.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037284484.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037279736.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037283357.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037289083.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037287001.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037278626.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037275598.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037280459.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037279330.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_037288931.1 7 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-69205 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription" XP_037283724.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037274782.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037287464.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037279972.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_037288356.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression" XP_037278828.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_037274661.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_037276098.1 7 MetaCyc: PWY-5074;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4 "Mevalonate degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Synthesis and degradation of ketone bodies";"Geraniol degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation" XP_037267998.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037268738.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277441.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-174411 "Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere" XP_037281196.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037274897.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_037277953.1 10 KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;Reactome: R-HSA-913709;Reactome: R-HSA-4719377 "N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation of mucins";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_037280272.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037280791.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_037288758.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037277619.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037279545.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037278841.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037281912.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037277714.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037283258.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_037280005.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_037282087.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037286419.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037277659.1 14 KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5078 "Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-isoleucine degradation II" XP_037274185.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037275158.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236 "Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"DNA methylation";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Meiotic synapsis";"Cleavage of the damaged purine";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_037292149.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037284221.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_037284476.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037276508.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271350.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037273974.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037286877.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037289030.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037289359.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037277879.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_037268955.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037289448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037292079.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037274793.1 4 Reactome: R-HSA-975144;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_037272508.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9609690 "Cilium Assembly";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Kinesins";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events" XP_037276309.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037282751.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037275579.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037271188.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037289894.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV" XP_037281401.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_037285973.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037279041.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037272069.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037271584.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-912446 "Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination" XP_037291137.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037277716.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037269662.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_037277715.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037284561.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037286709.1 3 Reactome: R-HSA-196819;MetaCyc: PWY-7369;KEGG: 00730+3.6.1.28 "Vitamin B1 (thiamin) metabolism";"Thiamine triphosphate metabolism";"Thiamine metabolism" XP_037287216.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944 "TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2" XP_037278868.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037289185.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037269921.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037273979.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037285882.1 13 MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism" XP_037287414.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037290176.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037268076.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037281113.1 8 KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_037277025.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_037288150.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037277645.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037286496.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037279749.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168271 "SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus" XP_037288287.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037288859.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281489.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes" XP_037274999.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037277677.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037270704.1 7 Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_037268066.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037271124.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037284521.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037274320.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037278359.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037285928.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037274123.1 7 MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_037276616.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037286310.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037286935.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037269037.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-977225 "Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Amyloid fiber formation" XP_037271977.1 10 Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-6365 "Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis" XP_037271912.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037287681.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_037287705.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037283877.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037269809.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399 "Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_037284407.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037284867.1 33 Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107 "ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_037286162.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037275414.1 3 KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581;Reactome: R-HSA-5578995 "Drug metabolism - other enzymes";"Methylation";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)" XP_037285941.1 20 MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5913 "Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)" XP_037283326.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_037272013.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037281197.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_037288020.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_037292070.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037288250.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037277968.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037276509.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_037284252.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037283476.1 22 Reactome: R-HSA-70263;MetaCyc: PWY-8013;MetaCyc: PWY-6992;MetaCyc: PWY-622;MetaCyc: PWY-5659;MetaCyc: PWY-6981;MetaCyc: PWY-6142;MetaCyc: PWY-5054;MetaCyc: PWY-5384;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-7385;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-621;Reactome: R-HSA-70171;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;MetaCyc: PWY-7238 "Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,5-anhydrofructose degradation";"Starch biosynthesis";"GDP-mannose biosynthesis";"Chitin biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch and sucrose metabolism";"Neutrophil degranulation";"1,3-propanediol biosynthesis (engineered)";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II" XP_037287259.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037274886.1 13 Reactome: R-HSA-975634;Reactome: R-HSA-216083;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3000178;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783 "Retinoid metabolism and transport";"Integrin cell surface interactions";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"ECM proteoglycans";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type" XP_037272900.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037272007.1 8 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6" XP_037272001.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037288748.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037284152.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037287722.1 52 Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-73780;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-749476;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Chain Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_037278751.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037282814.1 8 KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis" XP_037277886.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037271154.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_037276039.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037274887.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_037291920.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_037284099.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037277112.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037285741.1 5 MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism" XP_037288378.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037269744.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037280944.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037291562.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037289875.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037269173.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037286403.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037291719.1 10 MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722 "Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_037289768.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037277335.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037291418.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037281643.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_037273884.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037291019.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_037276498.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037278299.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037279058.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037276600.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_037284771.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_037282877.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037279011.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037286067.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037278381.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037292097.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037284293.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037281089.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037268488.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation" XP_037285216.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037284543.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037269611.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_037287327.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128 "Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling" XP_037270046.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-3371453 "Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response" XP_037287565.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037275375.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037268328.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037279456.1 7 KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)" XP_037268681.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287920.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037277092.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes" XP_037275791.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037272045.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037281765.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_037285840.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037281562.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_037288316.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037275162.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037283682.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_037291449.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837 "Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation" XP_037278657.1 12 KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4 "Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Ether lipid metabolism" XP_037280714.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037275186.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037278831.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037268150.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037268615.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037280883.1 1 Reactome: R-HSA-6787639 "GDP-fucose biosynthesis" XP_037269828.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037269112.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037280094.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_037285327.1 13 Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101 "Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation" XP_037282824.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037281801.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_037268476.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037289004.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037282447.1 7 Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519 "Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression" XP_037288633.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037283738.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037275169.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037289985.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037280722.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287234.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037269082.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037278358.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_037276989.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-5689880 "Methylation";"Ub-specific processing proteases" XP_037269724.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037277801.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_037273030.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037274132.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037289863.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation" XP_037289464.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037274294.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037278842.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037279180.1 3 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" XP_037282279.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037291549.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037271042.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037268696.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037280682.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037272394.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species" XP_037270960.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037271710.1 10 Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-7344;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821 "Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_037283536.1 17 KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-4202;MetaCyc: PWY-5695;MetaCyc: PWY-5532;Reactome: R-HSA-74259 "Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism" XP_037280079.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_037280575.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037287699.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037277042.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037278050.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037273836.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_037280403.1 4 KEGG: 00983+2.3.1.5;KEGG: 00633+2.3.1.5;KEGG: 00232+2.3.1.5;Reactome: R-HSA-156582 "Drug metabolism - other enzymes";"Nitrotoluene degradation";"Caffeine metabolism";"Acetylation" XP_037282030.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037286485.1 57 Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664 "Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation" XP_037271275.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_037271626.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037288398.1 7 MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176 "Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"UTP and CTP de novo biosynthesis" XP_037270163.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_037281564.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_037286807.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037277967.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_037278837.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037278440.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037278466.1 8 KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734;MetaCyc: PWY-7717;MetaCyc: PWY-5651;KEGG: 00380+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7765;MetaCyc: PWY-7733 "Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis" XP_037290832.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037269237.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_037279667.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037275403.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037277571.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037287935.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037285616.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_037288063.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_037285735.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_037284342.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289779.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037282431.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037286484.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037271157.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_037271871.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037278337.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997 "ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion" XP_037268675.1 9 MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - cytochrome P450" XP_037287284.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037272700.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-69541;Reactome: R-HSA-6804756 "Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Stabilization of p53";"Regulation of TP53 Activity through Phosphorylation" XP_037274086.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037291321.1 7 MetaCyc: PWY-6385;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6471 "Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)" XP_037269781.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037274212.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_037268439.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_037287318.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_037290286.1 20 Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400 "HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Polymerase switching";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER" XP_037273114.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037280479.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037284578.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037286933.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_037287534.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_037285711.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037271176.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037279569.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_037275880.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037285622.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-3359478;Reactome: R-HSA-71032;Reactome: R-HSA-3359475 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism";"Defective MMAA causes methylmalonic aciduria type cblA" XP_037284610.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037276444.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037273872.1 4 Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-166058 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_037268258.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037289782.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037289344.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037282095.1 4 MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism" XP_037287912.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037280823.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037278850.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_037286211.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_037283869.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037276141.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_037285597.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_037278376.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-75035;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-1433557;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750 "Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Signaling by SCF-KIT";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6" XP_037274838.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037279452.1 11 Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2 "Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Arginine biosynthesis" XP_037268065.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037269826.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268118.1 10 Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23 "HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation" XP_037277229.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_037268630.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037272694.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_037271369.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037287029.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037274532.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_037274337.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037268254.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037279306.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037276915.1 14 Reactome: R-HSA-5620912;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436 "Anchoring of the basal body to the plasma membrane";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic" XP_037286134.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037277559.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037291029.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_037271330.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037282543.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037284546.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037281138.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51 "Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism" XP_037282982.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_037287266.1 18 MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7197 "Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation" XP_037279458.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037281100.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-6840 "Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis" XP_037292146.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037283794.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037269333.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037283206.1 3 KEGG: 00330+3.5.3.11;Reactome: R-HSA-351143;MetaCyc: PWY-40 "Arginine and proline metabolism";"Agmatine biosynthesis";"Putrescine biosynthesis I" XP_037286614.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037272258.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037269035.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037270226.1 2 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "DNA methylation";"Cysteine and methionine metabolism" XP_037283011.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037283971.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_037287727.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037282520.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_037269061.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037283251.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037277333.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037282581.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-1362277 "Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex" XP_037287339.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_037282771.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037289121.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_037286669.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037274517.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037277414.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037268107.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-4381 "Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_037289538.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037277548.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037285273.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037275156.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037286264.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037288517.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037268774.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037285985.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037287536.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115 "3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037281908.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037276601.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037287479.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037275108.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037290935.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037275170.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037289728.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037278856.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037272067.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880 "FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Neddylation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases" XP_037282202.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037286494.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037290518.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037281248.1 4 KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1 "Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_037282491.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037285498.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037274575.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037273109.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037275283.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037290994.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037274192.1 52 Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837 "Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation" XP_037285670.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037283162.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165 "RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" XP_037270076.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037276312.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037268024.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037285866.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037287652.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282 "Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B" XP_037288321.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037288858.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037280406.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533 "Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gliotoxin biosynthesis" XP_037292077.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037279505.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037269321.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037289786.1 42 Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"Meiotic synapsis";"Meiotic recombination";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"DNA methylation";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)" XP_037279038.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037289881.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037279101.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408 "TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation" XP_037282448.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_037271147.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037282295.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037280325.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" XP_037281383.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037287809.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037282222.1 5 Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-9020702 "NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Interleukin-1 signaling" XP_037292130.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_037271898.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037281850.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037275116.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037285020.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037277651.1 5 KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_037285698.1 12 Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037276113.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_037284244.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037271019.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-9013973 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7" XP_037285413.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037277377.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037281901.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037284483.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037271367.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037282287.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037285257.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037288406.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037283594.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037286742.1 5 MetaCyc: PWY-7199;Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21 "Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037283714.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-437239 "RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"HCMV Early Events";"Cilium Assembly";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recycling pathway of L1" XP_037274356.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037281579.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism" XP_037288214.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037281680.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037282535.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037271125.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037275842.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037272301.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_037278532.1 179 Reactome: R-HSA-2408557;Reactome: R-HSA-2691232;Reactome: R-HSA-937042;Reactome: R-HSA-2979096;Reactome: R-HSA-5357905;Reactome: R-HSA-6782135;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-8866652;Reactome: R-HSA-174184;Reactome: R-HSA-2559580;Reactome: R-HSA-174154;Reactome: R-HSA-110320;Reactome: R-HSA-2672351;Reactome: R-HSA-6783310;Reactome: R-HSA-8941858;Reactome: R-HSA-8875360;Reactome: R-HSA-937072;Reactome: R-HSA-917729;Reactome: R-HSA-5693607;Reactome: R-HSA-975144;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5689901;Reactome: R-HSA-2173796;Reactome: R-HSA-5656121;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-977225;Reactome: R-HSA-5696397;Reactome: R-HSA-2871837;Reactome: R-HSA-6804756;Reactome: R-HSA-156902;Reactome: R-HSA-8849469;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6781823;Reactome: R-HSA-9645460;Reactome: R-HSA-1169408;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5654733;Reactome: R-HSA-6791226;Reactome: R-HSA-6807004;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9615710;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-3134975;Reactome: R-HSA-8876493;Reactome: R-HSA-179409;Reactome: R-HSA-450302;Reactome: R-HSA-6804760;Reactome: R-HSA-168638;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-3785653;Reactome: R-HSA-5689877;Reactome: R-HSA-975957;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-5610780;Reactome: R-HSA-209560;Reactome: R-HSA-1253288;Reactome: R-HSA-5655862;Reactome: R-HSA-201681;Reactome: R-HSA-9014325;Reactome: R-HSA-5696395;Reactome: R-HSA-168928;Reactome: R-HSA-75815;Reactome: R-HSA-917937;Reactome: R-HSA-211733;Reactome: R-HSA-162588;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-2644606;Reactome: R-HSA-5632684;Reactome: R-HSA-2122947;Reactome: R-HSA-9613829;Reactome: R-HSA-69017;Reactome: R-HSA-9636383;Reactome: R-HSA-174084;Reactome: R-HSA-5654732;Reactome: R-HSA-445989;Reactome: R-HSA-2559585;Reactome: R-HSA-450408;Reactome: R-HSA-1236382;Reactome: R-HSA-5693565;Reactome: R-HSA-174048;Reactome: R-HSA-901032;Reactome: R-HSA-3769402;Reactome: R-HSA-5205685;Reactome: R-HSA-8856825;Reactome: R-HSA-5696400;Reactome: R-HSA-209543;Reactome: R-HSA-8866654;Reactome: R-HSA-156827;Reactome: R-HSA-6782210;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-6781827;Reactome: R-HSA-937039;Reactome: R-HSA-349425;Reactome: R-HSA-8948747;Reactome: R-HSA-2565942;Reactome: R-HSA-5685942;Reactome: R-HSA-6804757;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-168927;Reactome: R-HSA-5689896;Reactome: R-HSA-8939236;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-937041;Reactome: R-HSA-5357956;Reactome: R-HSA-5668541;Reactome: R-HSA-9013973;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-2122948;Reactome: R-HSA-5675221;Reactome: R-HSA-975110;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5675482;Reactome: R-HSA-2559582;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5654727;Reactome: R-HSA-975163;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-400253;Reactome: R-HSA-202424;Reactome: R-HSA-912631;Reactome: R-HSA-5676590;Reactome: R-HSA-72706;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-175474;Reactome: R-HSA-450321;Reactome: R-HSA-2173795;Reactome: R-HSA-1799339;Reactome: R-HSA-1358803;Reactome: R-HSA-69541;Reactome: R-HSA-9033241;Reactome: R-HSA-936964;Reactome: R-HSA-8856828;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-2173788;Reactome: R-HSA-5654726;Reactome: R-HSA-182971;Reactome: R-HSA-5658442;Reactome: R-HSA-174490;Reactome: R-HSA-5678895;Reactome: R-HSA-205043;Reactome: R-HSA-174113;Reactome: R-HSA-4641263;Reactome: R-HSA-936440 "Selenocysteine synthesis";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"IRAK2 mediated activation of TAK1 complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of TNFR1 signaling";"Dual incision in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxidative Stress Induced Senescence";"APC/C:Cdc20 mediated degradation of Securin";"Translesion Synthesis by POLH";"Stimuli-sensing channels";"Fanconi Anemia Pathway";"Regulation of RUNX3 expression and activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Processing of DNA double-strand break ends";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Metalloprotease DUBs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Translesion synthesis by POLI";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Amyloid fiber formation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"FCERI mediated NF-kB activation";"Regulation of TP53 Activity through Phosphorylation";"Peptide chain elongation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Formation of TC-NER Pre-Incision Complex";"Alpha-protein kinase 1 signaling pathway";"ISG15 antiviral mechanism";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Late endosomal microautophagy";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of innate immune responses to cytosolic DNA";"InlA-mediated entry of Listeria monocytogenes into host cells";"APC-Cdc20 mediated degradation of Nek2A";"activated TAK1 mediates p38 MAPK activation";"Regulation of TP53 Activity through Methylation";"NOD1/2 Signaling Pathway";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Myoclonic epilepsy of Lafora";"Josephin domain DUBs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"Degradation of GLI1 by the proteasome";"NF-kB is activated and signals survival";"Downregulation of ERBB4 signaling";"Translesion synthesis by POLK";"TCF dependent signaling in response to WNT";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Formation of Incision Complex in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Ubiquitin-dependent degradation of Cyclin D";"Iron uptake and transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Budding and maturation of HIV virion";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Hedgehog 'on' state";"NOTCH1 Intracellular Domain Regulates Transcription";"Chaperone Mediated Autophagy";"CDK-mediated phosphorylation and removal of Cdc6";"Prevention of phagosomal-lysosomal fusion";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of FGFR3 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Oncogene Induced Senescence";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"APC/C:Cdc20 mediated degradation of Cyclin B";"ER Quality Control Compartment (ERQC)";"Deactivation of the beta-catenin transactivating complex";"Pink/Parkin Mediated Mitophagy";"Cargo recognition for clathrin-mediated endocytosis";"Dual Incision in GG-NER";"p75NTR recruits signalling complexes";"E3 ubiquitin ligases ubiquitinate target proteins";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"IRAK1 recruits IKK complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN localization";"Regulation of PLK1 Activity at G2/M Transition";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Degradation";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"TICAM1, RIP1-mediated IKK complex recruitment";"Ovarian tumor domain proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"IKK complex recruitment mediated by RIP1";"TNFR1-induced NFkappaB signaling pathway";"TNFR2 non-canonical NF-kB pathway";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Activated NOTCH1 Transmits Signal to the Nucleus";"Negative regulation of MAPK pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Glycogen synthesis";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Regulation of necroptotic cell death";"Senescence-Associated Secretory Phenotype (SASP)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Negative regulation of FGFR2 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"Neddylation";"UCH proteinases";"Circadian Clock";"Downstream TCR signaling";"Regulation of signaling by CBL";"NIK-->noncanonical NF-kB signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"G2/M Checkpoints";"Spry regulation of FGF signaling";"Assembly Of The HIV Virion";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SRP-dependent cotranslational protein targeting to membrane";"Downregulation of ERBB2:ERBB3 signaling";"Stabilization of p53";"Peroxisomal protein import";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR1 signaling";"EGFR downregulation";"Regulation of RAS by GAPs";"Membrane binding and targetting of GAG proteins";"Defective CFTR causes cystic fibrosis";"NRIF signals cell death from the nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of FZD by ubiquitination";"Negative regulators of DDX58/IFIH1 signaling" XP_037292150.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037275249.1 4 MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_037287856.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037273218.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037287328.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_037286391.1 29 Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-3108214;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6783310;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-110320 "Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"SUMOylation of DNA damage response and repair proteins";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH" XP_037274744.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA" XP_037278061.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037290740.1 26 Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-389960;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690 "Cilium Assembly";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events" XP_037275548.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037282057.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037276580.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037282197.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037271504.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037283151.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037287489.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037281679.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_037273278.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037285139.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037285975.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037280928.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037269357.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398 "Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway" XP_037283701.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037287683.1 3 Reactome: R-HSA-909733;Reactome: R-HSA-75102;Reactome: R-HSA-77042 "Interferon alpha/beta signaling";"C6 deamination of adenosine";"Formation of editosomes by ADAR proteins" XP_037284394.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy" XP_037281855.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037289116.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037286423.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037288949.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037291760.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_037268554.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037291840.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037287429.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_037288315.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037268161.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_037277137.1 5 KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I" XP_037271349.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037291559.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037271732.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-909733 "Interferon gamma signaling";"Interferon alpha/beta signaling" XP_037285900.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037281760.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-156711 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events" XP_037286189.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037283270.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037283659.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037290712.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037268308.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037286602.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037270925.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037277902.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037276569.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037279568.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_037276313.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate" XP_037271587.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037269878.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037284282.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-7900;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate" XP_037289501.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_037289483.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037284413.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037283697.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events" XP_037286501.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037279503.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037268398.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037281323.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_037282685.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037283386.1 8 MetaCyc: PWY-5740;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47 "GDP-L-colitose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_037291595.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037270267.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_037283098.1 12 MetaCyc: PWY-1861;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism" XP_037277496.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037282938.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_037280321.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037289084.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037270537.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283048.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_037287372.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037285867.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037288402.1 7 KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6737 "Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation V" XP_037271182.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_037277271.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037274901.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037287201.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-164378 "PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling" XP_037271419.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037288387.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037272253.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_037287297.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283710.1 24 Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events" XP_037288771.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692 "MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity" XP_037281451.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_037281574.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037287698.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037282213.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium" XP_037276120.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037268715.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037272930.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037292009.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_037271905.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037277493.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037268022.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_037272387.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037288470.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037285932.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037289614.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037281200.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037272578.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037269159.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037277903.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037287793.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8963901 "Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Cell surface interactions at the vascular wall";"VLDL assembly";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Scavenging by Class F Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Chylomicron remodeling" XP_037289697.1 20 Reactome: R-HSA-389357;Reactome: R-HSA-3371571;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1 "CD28 dependent PI3K/Akt signaling";"HSF1-dependent transactivation";"Human papillomavirus infection";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTORC1-mediated signalling";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"Macroautophagy";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection" XP_037285915.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037274355.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037288929.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037274121.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_037288555.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_037268463.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037284470.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037280158.1 3 Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581 "Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation" XP_037283094.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037292028.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037285700.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037277799.1 8 MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7733;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis" XP_037280651.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037286806.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037269883.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037277658.1 14 MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-5101;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;KEGG: 00270+2.6.1.42 "L-leucine degradation III";"L-isoleucine degradation II";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"Cysteine and methionine metabolism" XP_037271618.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037291086.1 11 Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037275028.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_037284519.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037279492.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-180585 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"UCH proteinases";"Neddylation";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G" XP_037284518.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037283085.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037280598.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_037268431.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037271381.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037282025.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037275321.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277062.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_037283104.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037288312.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037287215.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037283722.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_037286600.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037291351.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037276534.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_037274858.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037274872.1 14 KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4 "Glycerophospholipid metabolism";"Synthesis of PC";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Sphingolipid metabolism";"Ether lipid metabolism" XP_037291387.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037289775.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037282445.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037269915.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037280042.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037288550.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037274853.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037274533.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_037269795.1 13 Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-216083 "Collagen degradation";"Crosslinking of collagen fibrils";"Signaling by PDGF";"Laminin interactions";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"NCAM1 interactions";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Integrin cell surface interactions" XP_037274273.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037286763.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_037279182.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037284354.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037277442.1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation III (Serratia)" XP_037281042.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037289206.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037278824.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_037273271.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037287917.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037269560.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037286282.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408 "TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation" XP_037291706.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037275919.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037281430.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_037277080.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_037284449.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037288324.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037269127.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037277679.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037281344.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037288601.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-432142 "VLDL assembly";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Chylomicron clearance";"LDL remodeling";"Chylomicron assembly";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Platelet sensitization by LDL" XP_037288869.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037280036.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037285000.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037269898.1 29 Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Meiotic recombination";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_037288619.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_037272030.1 6 MetaCyc: PWY-5651;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-6309 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_037276863.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037283550.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037278298.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037270813.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-7230;Reactome: R-HSA-2142789 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis" XP_037286682.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037279070.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_037276524.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037272204.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_037270661.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037289110.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278534.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037292014.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_037268877.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037281771.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037278153.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25 "Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037281979.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037288423.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037286887.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_037278506.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037275742.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037285145.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_037269689.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037274538.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_037285456.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037268520.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" XP_037268259.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037277586.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_037283839.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271145.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_037273646.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450" XP_037274019.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_037281049.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037287053.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-6798695;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Neutrophil degranulation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037276767.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_037282438.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037286409.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037279993.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037283264.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037286789.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)" XP_037278633.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037279159.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037277090.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes" XP_037274223.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_037272320.1 15 Reactome: R-HSA-8863795;Reactome: R-HSA-9665246;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-1227986;Reactome: R-HSA-9665250;Reactome: R-HSA-5637810;Reactome: R-HSA-9634285 "Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Overexpressed ERBB2" XP_037281594.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037268384.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_037268333.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037282233.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_037289844.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037269609.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037274428.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037290263.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_037275843.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037289658.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037282969.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037281976.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037277676.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037273825.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037290041.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037284662.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037277427.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037281766.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037280203.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_037272360.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037282728.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239 "COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1" XP_037291767.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037270961.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037286911.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_037276361.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037288344.1 5 KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation" XP_037286460.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037274989.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037274098.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037289087.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037274607.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-5981 "Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III" XP_037273711.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037268825.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037290281.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037276927.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037291457.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_037291521.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_037281964.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_037282079.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601 "GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_037281201.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037272784.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037291572.1 3 Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037271297.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037281586.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037276473.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037283141.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037269776.1 6 MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_037290861.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-73728;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-1912408 "RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"Meiotic synapsis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"RNA Polymerase I Promoter Opening";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation" XP_037282284.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037282647.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037272466.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037271666.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037285739.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_037276730.1 6 MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36 "Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" XP_037287245.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037274488.1 29 Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167158 "HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex" XP_037284602.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037277698.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037285951.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037288480.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037280865.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037276115.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037269038.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685 "Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy" XP_037287401.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-168276 "tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways" XP_037286065.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037291432.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037281037.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_037288399.1 7 KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3 "Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism" XP_037282082.1 1 MetaCyc: PWY-7883 "Anhydromuropeptides recycling II" XP_037284456.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037285981.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037268433.1 7 KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-163210 "Photosynthesis";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling" XP_037273879.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_037287094.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037271368.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037281991.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037284422.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037284971.1 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism" XP_037279121.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037268307.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037272600.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" XP_037288908.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037284199.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037283301.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037283091.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037286518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037278683.1 40 MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7778;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7094;MetaCyc: PWY-6435;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5109;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7654;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-7216;MetaCyc: PWY-5177;MetaCyc: PWY-1361;MetaCyc: PWY-6583 "Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Fatty acid elongation";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Benzoate degradation";"beta-Alanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Tryptophan metabolism";"Lysine degradation";"Butanoate metabolism";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I" XP_037274682.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037282707.1 13 MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)" XP_037278338.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_037275727.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_037279352.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037287007.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037281376.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037282246.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037277086.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037288427.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037280117.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037275844.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037284384.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037287772.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037287370.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037292001.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_037277069.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037279435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037291811.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037286433.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289661.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037278936.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268085.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037282457.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037281924.1 11 MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42 "TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_037290717.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295 "Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation" XP_037281462.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_037287270.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037290310.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_037269574.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy" XP_037278731.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037285929.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037290290.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037268482.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037276681.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037277026.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037281148.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037268266.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037278049.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037277814.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_037268425.1 5 Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-193648;Reactome: R-HSA-446388;Reactome: R-HSA-416482 "Rho GTPase cycle";"G beta:gamma signalling through CDC42";"NRAGE signals death through JNK";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events" XP_037281351.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037269267.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037291492.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037271475.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.16 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037273321.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037268121.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037291155.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037292076.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037282094.1 4 Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3;MetaCyc: PWY-5651 "Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_037287700.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037283012.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_037271215.1 13 KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7226 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_037289360.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037271289.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037288111.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037275489.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037281879.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269270.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037289639.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037268158.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_037285770.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037273036.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037281117.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037270791.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_037281381.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037277182.1 15 Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-174048 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_037279691.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037269498.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037290646.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037285549.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037285140.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037291556.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037284594.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037287559.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_037270057.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037269181.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_037273826.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037284741.1 5 Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_037287626.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037287561.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037290831.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_037289821.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_037281166.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_037282823.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037286788.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037268382.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037282124.1 16 KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5749;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5913 "Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)" XP_037277394.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_037281940.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037273311.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037286579.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_037280186.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037269060.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037274176.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_037290023.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231 "SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037282995.1 2 MetaCyc: PWY-7560;KEGG: 00900+2.7.7.60 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" XP_037282874.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_037277771.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037276356.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_037272467.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037283643.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037291857.1 4 MetaCyc: PWY-5028;KEGG: 00340+4.3.1.3;MetaCyc: PWY-5030;Reactome: R-HSA-70921 "L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism" XP_037280693.1 4 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037285254.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037275820.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037276611.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037275131.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_037283673.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037281295.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037291377.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037272566.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037287655.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037287057.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037268562.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037284845.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_037282013.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_037291248.1 7 Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862 "HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Translesion synthesis by POLK" XP_037286230.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037291301.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037271586.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037286363.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037281013.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283387.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781 "Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)" XP_037290681.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037281455.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037279115.1 6 Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695 "HS-GAG degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism";"MPS VII - Sly syndrome";"Neutrophil degranulation" XP_037273229.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037283106.1 12 MetaCyc: PWY-1861;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_037280884.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_037289059.1 32 Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex" XP_037282886.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037271156.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287895.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037276362.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037287706.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359473;Reactome: R-HSA-3359474 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC" XP_037286774.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037275123.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037283017.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037277233.1 10 Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6901 "Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation" XP_037268367.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037287901.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037291218.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283302.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037269591.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037282519.1 4 Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037283838.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037283093.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037268927.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037276527.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_037276108.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037283343.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037282613.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037282970.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037271259.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_037289160.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037286062.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037282851.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037285956.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037291127.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_037279289.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037274383.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037274565.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037281036.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_037288178.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "Downstream signal transduction";"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_037276153.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037288930.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037278028.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037274742.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037286454.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion" XP_037283037.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037289662.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037286954.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037268623.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278823.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037269624.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037274860.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_037274787.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_037268806.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037269259.1 5 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB" XP_037286711.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037284045.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037274480.1 4 KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_037278901.1 14 Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497 "Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate transformations I";"Cyanoamino acid metabolism";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)" XP_037271172.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037285315.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" YP_008999527.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037288554.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037286945.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037274235.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037277376.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037270921.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037269656.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037273198.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037280002.1 57 Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880 "FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"UCH proteinases";"Neddylation";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases" YP_008999534.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037276891.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037288447.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037277041.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037285964.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037285858.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037277470.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287815.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037279437.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037286582.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037273375.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_037283308.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037274292.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690 "Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events" XP_037271820.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_037281900.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037288379.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037272604.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942 "Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism" XP_037279674.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037275112.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism" XP_037276954.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" XP_037271237.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_037285061.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037268000.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037282727.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones" XP_037277891.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037277369.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037273976.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037284150.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037274382.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037269299.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_037278524.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037268001.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037272278.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037291988.1 1 MetaCyc: PWY-5901 "2,3-dihydroxybenzoate biosynthesis" XP_037271486.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_037279176.1 17 Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-174048 "Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_037286257.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_037268420.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037292078.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037284301.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037280222.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037275509.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_037282730.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_037281483.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_037271789.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_037271135.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037280346.1 4 KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;KEGG: 00633+2.3.1.5;Reactome: R-HSA-156582 "Drug metabolism - other enzymes";"Caffeine metabolism";"Nitrotoluene degradation";"Acetylation" XP_037275113.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_037282885.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037271533.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037272318.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037289753.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037283780.1 25 Reactome: R-HSA-9616222;Reactome: R-HSA-8940973;Reactome: R-HSA-8941333;Reactome: R-HSA-8951936;Reactome: R-HSA-8936459;Reactome: R-HSA-8939243;Reactome: R-HSA-8941332;Reactome: R-HSA-8931987;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-8941284;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8939247;Reactome: R-HSA-8941326;Reactome: R-HSA-8939246;Reactome: R-HSA-8939236;Reactome: R-HSA-8951911;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8949275 "Transcriptional regulation of granulopoiesis";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates p14-ARF";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates estrogen receptor mediated transcription";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 Regulates Immune Response and Cell Migration" XP_037282870.1 9 MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" XP_037275628.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-427413 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression" XP_037290550.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037282793.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604 "RAF/MAP kinase cascade";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling" XP_037284139.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037277218.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037290869.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037292124.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER" XP_037282779.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_037281309.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037272000.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)" XP_037278694.1 9 MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004 "Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I" XP_037270048.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_037278006.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037289048.1 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" XP_037291540.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037271869.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037271945.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037289528.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037281120.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037282815.1 8 KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1 "Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis" XP_037282051.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485 "CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis" XP_037283804.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037279347.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037277382.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037286180.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037279431.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037274226.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037272386.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-71336;MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180 "Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation" XP_037291125.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037279246.1 6 MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-7356 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)" XP_037268522.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037290535.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037275160.1 42 Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-110329;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582 "RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"Meiotic synapsis";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)" XP_037291412.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037270810.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_037287888.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037283344.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037271487.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037277933.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_037274783.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_037274007.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037290664.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037287979.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037271341.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037278734.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037271456.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278121.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037287546.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037283061.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037278896.1 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" XP_037271193.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037284646.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037268746.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283097.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037275004.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037271859.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037286639.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_037283250.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037289645.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037286498.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols" XP_037268163.1 27 Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-159227;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-674695;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-159236;Reactome: R-HSA-167200;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-9010553;Reactome: R-HSA-159230;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of the SLBP independent Mature mRNA";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037284740.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695 "Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation" XP_037277464.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_037268437.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037275495.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037279145.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_037281454.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037276751.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037278893.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_037274003.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_037283150.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037281762.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69202 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition" XP_037270146.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603 "Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Neddylation";"UCH proteinases" XP_037281975.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037274423.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037285913.1 9 Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-975634 "HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport" XP_037269977.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037276729.1 13 MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037291867.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_037275839.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037269785.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037278891.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037284172.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation" XP_037286548.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037280597.1 7 Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507 "Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_037285685.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413 "SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression" XP_037269595.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037290267.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_037283447.1 9 Reactome: R-HSA-8963684;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5 "Tyrosine catabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_037281435.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037275597.1 11 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-167162 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape" XP_037289604.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037275035.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037282734.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037278578.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037288965.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037279288.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037281004.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037269409.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037277946.1 10 Reactome: R-HSA-913709;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;MetaCyc: PWY-7661;Reactome: R-HSA-162699;MetaCyc: PWY-7921;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-4717374 "O-linked glycosylation of mucins";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_037277312.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Gap junction degradation";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_037282093.1 4 MetaCyc: PWY-5651;KEGG: 00380+3.7.1.3;Reactome: R-HSA-71240;MetaCyc: PWY-6309 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_037287097.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037276392.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037282700.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037277459.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037281780.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037277474.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-165054 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA" XP_037282875.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037287555.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037283158.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037277370.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037283712.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037279243.1 5 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_037277045.1 9 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-446343;KEGG: 05165+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Human papillomavirus infection";"Cell-extracellular matrix interactions";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037280669.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_037282088.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037290215.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_037273883.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037271791.1 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" XP_037275356.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037288318.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037291804.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037268370.1 7 Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842 "Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"HDMs demethylate histones" XP_037281169.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_037281079.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_037268741.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037268023.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037282678.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037274836.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037292125.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_037283216.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation" XP_037281279.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" YP_008999528.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037268211.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037279610.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037287761.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037284187.1 13 KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_037278386.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037287703.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037283248.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037286666.1 2 Reactome: R-HSA-606279;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway" XP_037281045.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037286240.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037281086.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037269416.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037291221.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037280442.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037283830.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_037286591.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037279353.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_037268511.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037290703.1 6 MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663 "Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I" XP_037279021.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037289874.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5626467;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-389359;Reactome: R-HSA-114604 "Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"RHO GTPases activate PAKs";"Myogenesis";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases activate IQGAPs";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"CD28 dependent Vav1 pathway";"GPVI-mediated activation cascade" XP_037288182.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037291810.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037274276.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037288228.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037281369.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production" XP_037279504.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037274380.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037275150.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037280258.1 11 Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway";"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037283050.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037287430.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events" XP_037287289.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_037269606.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037287760.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_037278620.1 5 KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621 "Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism" XP_037285650.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037277374.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037277892.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_037289408.1 56 Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-195253 "Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex" XP_037282762.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037277940.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037287550.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037273667.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037271565.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037271676.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037287763.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037276214.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037291736.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037274333.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037273916.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037282903.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_037285574.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_037289303.1 7 Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352 "Synthesis of PI";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis" XP_037289843.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037283661.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037279821.1 6 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292 "Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome" XP_037281118.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037279230.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037286226.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037271716.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_037274593.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" YP_008999533.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037287249.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" XP_037272500.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037270892.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037276586.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_037282616.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037276249.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037270039.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_037271339.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037273318.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037276749.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037287385.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037288396.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037268304.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037283299.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037290882.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037270807.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037286852.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037282517.1 4 Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037278340.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997 "ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion" XP_037273287.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037285250.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037292157.1 22 MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-6958;MetaCyc: PWY-7602 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037290011.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_037273411.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037276889.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_037268386.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_037287195.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_037272340.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport" XP_037273435.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037291604.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037290473.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037287467.1 11 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037281774.1 10 Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1 "Recycling pathway of L1";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RSK activation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection" XP_037276979.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110314 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex" XP_037286662.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037288899.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_037269827.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037281109.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037290982.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_037274202.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_037290096.1 6 KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807 "Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_037288514.1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471 "Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Retinoid metabolism and transport";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"VLDL assembly";"LDL clearance";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors" XP_037282677.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037277811.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037272491.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-69273 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition" XP_037287090.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037282602.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037292139.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037276000.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037274590.1 5 Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111457 "SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria" XP_037287654.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037280873.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_037268764.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277789.1 11 Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801 "Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD" XP_037287177.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037270370.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287416.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037280014.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_037292013.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_037287316.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037278839.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037270567.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464 "Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins" XP_037291322.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037292086.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268159.1 11 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380320 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes" XP_037268147.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037279282.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037280497.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037291471.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037270962.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037268203.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_037281661.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037281250.1 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_037271785.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037291714.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037281904.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037277742.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037281236.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037271160.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037271345.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037284529.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-735;Reactome: R-HSA-9033241;MetaCyc: PWY-7858 "Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II" XP_037269412.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037292159.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037279320.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_037268303.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037282708.1 13 MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538 "Pyruvate fermentation to acetate V";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI" XP_037268052.1 11 Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795 "ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling" XP_037269366.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037269784.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037286078.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis" XP_037271447.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037287870.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037276119.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_037278005.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037286799.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037276727.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037277439.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_037272108.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_037280384.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037289428.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037289374.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I" XP_037281927.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054 "SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA" XP_037288958.1 6 MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_037280332.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277969.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_037289349.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_037285272.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037278855.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037286458.1 9 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037278275.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_037292105.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037268353.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037277053.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037268377.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037271896.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037284227.1 4 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_037277436.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_037278427.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037283702.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037282958.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037271784.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_037285283.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037268247.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037284210.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037289812.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037272186.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037270007.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037275188.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037291560.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037278998.1 9 MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7902 "Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis" XP_037285843.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037283356.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037280270.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037280356.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746 "Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein" XP_037287767.1 3 KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669 "Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_037274279.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037269562.1 5 Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" XP_037288938.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037285285.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037268394.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037270779.1 5 Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097 "NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway" XP_037274567.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037277477.1 8 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins" XP_037278830.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_037271257.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037288042.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037286969.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization" XP_037282344.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037280285.1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_037282748.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037276953.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_037269866.1 9 Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-193648 "VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"NRAGE signals death through JNK" XP_037288729.1 4 KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;KEGG: 00633+2.3.1.5;Reactome: R-HSA-156582 "Drug metabolism - other enzymes";"Caffeine metabolism";"Nitrotoluene degradation";"Acetylation" XP_037284586.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037289479.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037278377.1 17 KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1433557;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Signaling by SCF-KIT";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis" XP_037284751.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037282547.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037277379.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037274584.1 6 Reactome: R-HSA-5628897;KEGG: 00480+1.8.1.7;Reactome: R-HSA-3299685;MetaCyc: PWY-4081;Reactome: R-HSA-499943;Reactome: R-HSA-2408550 "TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"Glutathione-peroxide redox reactions";"Interconversion of nucleotide di- and triphosphates";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_037286970.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_037272609.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037288193.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037287798.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037283064.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037288078.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037280554.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037286599.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037277105.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037274579.1 6 MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6731 "Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III" XP_037274170.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037278183.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037287379.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037287397.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_037274636.1 18 MetaCyc: PWY-1622;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263 "Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Gluconeogenesis" XP_037283096.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_037283991.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_037290000.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Interferon gamma signaling";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors" XP_037277136.1 5 MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism" XP_037268598.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037286500.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037277171.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037280008.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037270811.1 2 Reactome: R-HSA-3772470;Reactome: R-HSA-201681 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT" XP_037285480.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_037277585.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_037271426.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037281264.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037269584.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037282729.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_037268983.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_037287867.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037290580.1 5 MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_037277600.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167242 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_037288076.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037275540.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_037289983.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_037272181.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_037288926.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037284582.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037286389.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037280530.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037290690.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037279175.1 17 Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-176409 "Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins" XP_037284669.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037282788.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037278350.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037283349.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-977606;Reactome: R-HSA-375276;Reactome: R-HSA-174577 "G alpha (i) signalling events";"Regulation of Complement cascade";"Peptide ligand-binding receptors";"Activation of C3 and C5" XP_037286446.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037279170.1 6 KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Methane metabolism";"Serine biosynthesis" XP_037281560.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037273312.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037276966.1 6 MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6 "Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism" XP_037281761.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition" XP_037286487.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism" XP_037271870.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037276609.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037271067.1 5 MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)" XP_037279033.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037278300.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037279595.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037277164.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_037289731.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037286431.1 5 Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_037277475.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-165054 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA" XP_037287482.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_037271231.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_037282060.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_037282901.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_037284628.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037269796.1 13 Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320 "NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Laminin interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Collagen degradation";"Integrin cell surface interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation" XP_037271262.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037271318.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_037270255.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037288471.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037280929.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037268464.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037284965.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_037278835.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037269490.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037291627.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037283717.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037278919.1 8 MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_037284864.1 3 Reactome: R-HSA-156581;KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995 "Methylation";"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)" XP_037282294.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037277037.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037280528.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037289394.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037283051.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037287187.1 5 MetaCyc: PWY-7210;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I" XP_037287298.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037291903.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037268728.1 7 MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037269077.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037286929.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-168325 "tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis" XP_037273837.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037283660.1 4 Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037287189.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-917729 "Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037290295.1 32 Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167238 "RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation" XP_037268663.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037269575.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation" XP_037287794.1 7 Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II" XP_037269268.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037272711.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037284697.1 9 Reactome: R-HSA-110329;Reactome: R-HSA-9657050;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Defective OGG1 Localization";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" XP_037288320.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037291907.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037278523.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037276970.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_037287956.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289358.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_037286351.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037279793.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_037291710.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_037268493.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" XP_037280645.1 4 Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3;MetaCyc: PWY-5651 "Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_037291737.1 5 MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037286169.1 31 MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;MetaCyc: PWY-6113;Reactome: R-HSA-163765;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-7664;MetaCyc: PWY-7723;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799 "Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"ChREBP activates metabolic gene expression";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Bacterial bioluminescence";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)" XP_037274895.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037287008.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037271063.1 13 KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Thermogenesis";"mTOR signaling pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037277383.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037268064.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037281147.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037277729.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037283384.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289062.1 32 Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome" XP_037284479.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_037273449.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037288904.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037279454.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037277905.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037279388.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037277806.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037284998.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037272095.1 17 MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2 "Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Carnitine metabolism";"Candicidin biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes" XP_037278542.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_037285965.1 10 Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-210744 "NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_037277449.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037286439.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037271705.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037287918.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037292182.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037291581.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037277546.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_037287925.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037286063.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037290048.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037268281.1 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037290720.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037282682.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037271370.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037290293.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037281553.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_037288795.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037287567.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037288861.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277230.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape" XP_037289382.1 5 KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_037283642.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037276279.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037279959.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037282244.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037271577.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway" XP_037277678.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037279444.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037286595.1 3 MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_037281556.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037290481.1 1 Reactome: R-HSA-419771 "Opsins" XP_037284560.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037270349.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287247.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_037286029.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037277438.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_037280656.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037278852.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037283436.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751 "Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity" XP_037276887.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_037277411.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037269610.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037288026.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_037273941.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037268020.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037271950.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_037282914.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_037278383.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037268289.1 5 MetaCyc: PWY-8010;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00270+1.1.1.95 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis";"Cysteine and methionine metabolism" XP_037288138.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037285738.1 5 KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_037273827.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037274082.1 7 KEGG: 00100+1.3.1.70;MetaCyc: PWY-6074;Reactome: R-HSA-9022692;Reactome: R-HSA-191273;MetaCyc: PWY-8026;MetaCyc: PWY-7154;MetaCyc: PWY-2541 "Steroid biosynthesis";"Zymosterol biosynthesis";"Regulation of MECP2 expression and activity";"Cholesterol biosynthesis";"Sterol biosynthesis (methylotrophs)";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)" XP_037281187.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037287739.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037275092.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037268519.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037282002.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_037292098.1 2 Reactome: R-HSA-432047;Reactome: R-HSA-432040 "Passive transport by Aquaporins";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037274526.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_037291726.1 26 Reactome: R-HSA-5696397;Reactome: R-HSA-6804114;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-4615885;Reactome: R-HSA-69091;Reactome: R-HSA-1362277;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5656121;Reactome: R-HSA-174417;Reactome: R-HSA-5696400 "Gap-filling DNA repair synthesis and ligation in GG-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA replication proteins";"Polymerase switching";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion synthesis by POLI";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER" XP_037289979.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037281473.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling" XP_037268836.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037286463.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037279179.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_037277385.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037274794.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_037271340.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037270064.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037272009.1 1 KEGG: 00760+1.4.1.21 "Nicotinate and nicotinamide metabolism" XP_037289746.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037281907.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037287190.1 10 Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-9636383 "Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Prevention of phagosomal-lysosomal fusion" XP_037277957.1 10 Reactome: R-HSA-4719360;Reactome: R-HSA-162699;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7979 "Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)" XP_037278921.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037284493.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037286072.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037277154.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037282739.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_037283324.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;Reactome: R-HSA-1475029 "3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide" XP_037291534.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037269331.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037269347.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_037287060.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_037275782.1 2 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037269375.1 1 Reactome: R-HSA-381426 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037284583.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037286739.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037281536.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_037279168.1 15 MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;Reactome: R-HSA-70171 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis" XP_037287096.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037283980.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037282019.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_037268755.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037276871.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037288927.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037282827.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037281016.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037281558.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_037277238.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037287362.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037281871.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037282731.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332 "Activation of AMPK downstream of NMDARs";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin" XP_037286017.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037290604.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037287808.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037276926.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037290250.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037283732.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037274426.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037277955.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037285612.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037270086.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037282693.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037269411.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037272080.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037282406.1 3 KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_037270047.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_037274577.1 6 Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1 "Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism" XP_037286478.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037291679.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037279963.1 12 Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243 "RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery" XP_037279672.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037284318.1 6 Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275 "ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation" XP_037272949.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037278949.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037283052.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037282902.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_037271448.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037287449.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037284386.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037279029.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037282058.1 6 MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183 "3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol" XP_037283252.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037286236.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037278356.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037288481.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037282041.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037283833.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037273479.1 7 Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148 "Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PG" XP_037292101.1 2 Reactome: R-HSA-432047;Reactome: R-HSA-432040 "Passive transport by Aquaporins";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037275168.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037269830.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037269182.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_037278816.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037269576.1 9 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" XP_037284857.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037272959.1 12 KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4 "Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism" XP_037291930.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037279833.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037291280.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037279455.1 7 Reactome: R-HSA-446193;Reactome: R-HSA-5633231;MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6470;MetaCyc: PWY-6385 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)" XP_037284279.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037282822.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037282842.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_037268393.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037268274.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-532668 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037280799.1 11 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_037292080.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037291745.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_037268119.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037285414.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268381.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037268265.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037270319.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486 "MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis" XP_037271184.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357 "TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1" XP_037292121.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_037272701.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-2559585;Reactome: R-HSA-5689880;Reactome: R-HSA-69541;Reactome: R-HSA-6804756 "Oxidative Stress Induced Senescence";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"Oncogene Induced Senescence";"Ub-specific processing proteases";"Stabilization of p53";"Regulation of TP53 Activity through Phosphorylation" XP_037282957.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037291231.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037274021.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037288141.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_037274959.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_037290022.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037270317.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037289633.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722 "Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_037276898.1 8 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-8953750 "Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6" XP_037271984.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037287171.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_037278397.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037287569.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_037279459.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037276195.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_037282032.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037268165.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037271733.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-877300 "Interferon alpha/beta signaling";"Interferon gamma signaling" XP_037274781.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037271906.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037270054.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037289764.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037287454.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_037269374.1 1 Reactome: R-HSA-381426 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037271712.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783 "Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome" XP_037282836.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037282832.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_037276475.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037277486.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_037283214.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_037292104.1 2 Reactome: R-HSA-432040;Reactome: R-HSA-432047 "Vasopressin regulates renal water homeostasis via Aquaporins";"Passive transport by Aquaporins" XP_037291388.1 12 Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037290863.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037286603.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037291121.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037271792.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037271476.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037282516.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_037292008.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion" XP_037268491.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_037287800.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_037268057.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037277072.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037269722.1 26 Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Cilium Assembly";"Mitotic Prometaphase";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"HCMV Early Events" XP_037283572.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037289014.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037287175.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037282983.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_037275672.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_037274139.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_037274119.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037272818.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037280547.1 9 Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112 "Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification" YP_008999538.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037278924.1 5 MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523 "Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)" XP_037269979.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_037272031.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16 "Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis" XP_037283369.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037280419.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037272918.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037279106.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037288446.1 4 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037271020.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-9013973 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7" XP_037292174.1 11 KEGG: 04070+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517 "Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane" XP_037273295.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037271529.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037282991.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037271663.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037277450.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037278312.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037291101.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037273335.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037281249.1 4 Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_037282545.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037291606.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex" XP_037270300.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037268011.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037287059.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_037281190.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037274344.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_037271240.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287933.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037288479.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037286128.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037284748.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037269140.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037271944.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-977225 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation" XP_037290732.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037276917.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037273107.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037284526.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_037286388.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037280273.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling" XP_037281485.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_037283461.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037284143.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state" XP_037279638.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037282648.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037281828.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921 "TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_037282752.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037274194.1 6 Reactome: R-HSA-70921;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;KEGG: 00340+2.1.2.5;KEGG: 00670+2.1.2.5;MetaCyc: PWY-5497 "Histidine catabolism";"One carbon pool by folate";"L-histidine degradation III";"Histidine metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)" XP_037289279.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037281080.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy" XP_037269175.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037271964.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport" XP_037283049.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183 "Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand" XP_037287859.1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" XP_037283265.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037271840.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037271187.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037274435.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_037269914.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037283776.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037271951.1 12 KEGG: 00670+2.1.2.2;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;Reactome: R-HSA-196780 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Purine metabolism";"Purine metabolism";"Biotin transport and metabolism" XP_037274764.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome" XP_037285541.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"HS-GAG degradation" XP_037288301.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037287288.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_037283083.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037288075.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037290801.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_037271536.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037286641.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037271903.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037268268.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_037289750.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037284524.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_037290784.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_037269811.1 1 Reactome: R-HSA-446199 "Synthesis of Dolichyl-phosphate" XP_037285141.1 9 Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962 "Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex" XP_037283139.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037284297.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037282996.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037281704.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037288376.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037280931.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037277628.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation" XP_037281785.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_037285562.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037271190.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037279096.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287006.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037281398.1 13 KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18 "Glutathione metabolism";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione conjugation";"Drug metabolism - cytochrome P450" XP_037287857.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037278185.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037268781.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278484.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037277572.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037280202.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_037277172.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037272683.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037268227.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037281481.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_037278693.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_037271161.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037276614.1 10 KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484 "Galactose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)" XP_037285908.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037286411.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037277774.1 30 Reactome: R-HSA-8854050;Reactome: R-HSA-917937;Reactome: R-HSA-195253;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-187577 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Iron uptake and transport";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21" XP_037275118.1 40 Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167238 "RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation" XP_037281428.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037275729.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_037283152.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037269462.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037285448.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037272338.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_037270656.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-2559582;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427359 "HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"Cleavage of the damaged purine";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression" XP_037279921.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_037269350.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037287677.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037270074.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037278374.1 17 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Relaxin signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6" XP_037282439.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037272367.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_037287396.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_037268061.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037283719.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037271530.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037281852.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519 "TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression" XP_037274848.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_037281549.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037268929.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037282225.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-5205685 "Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy" XP_037273453.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037279735.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037268311.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037283608.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037287322.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_037274397.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_037273886.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037285832.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037274174.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037268447.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_037276180.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037274319.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_037279445.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037280488.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037288934.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037271279.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037282878.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037268173.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037278530.1 179 Reactome: R-HSA-110320;Reactome: R-HSA-8941858;Reactome: R-HSA-2672351;Reactome: R-HSA-6783310;Reactome: R-HSA-8875360;Reactome: R-HSA-937072;Reactome: R-HSA-975144;Reactome: R-HSA-5693607;Reactome: R-HSA-917729;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5689901;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5656121;Reactome: R-HSA-2173796;Reactome: R-HSA-2691232;Reactome: R-HSA-2408557;Reactome: R-HSA-937042;Reactome: R-HSA-2979096;Reactome: R-HSA-5357905;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-6782135;Reactome: R-HSA-174154;Reactome: R-HSA-8866652;Reactome: R-HSA-174184;Reactome: R-HSA-2559580;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-9645460;Reactome: R-HSA-6781823;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-1169408;Reactome: R-HSA-6791226;Reactome: R-HSA-5654733;Reactome: R-HSA-180534;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-5696397;Reactome: R-HSA-2871837;Reactome: R-HSA-6804756;Reactome: R-HSA-156902;Reactome: R-HSA-8849469;Reactome: R-HSA-168638;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-3785653;Reactome: R-HSA-5689877;Reactome: R-HSA-975957;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-6807004;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9615710;Reactome: R-HSA-1169091;Reactome: R-HSA-3134975;Reactome: R-HSA-8876493;Reactome: R-HSA-2173791;Reactome: R-HSA-179409;Reactome: R-HSA-6804760;Reactome: R-HSA-450302;Reactome: R-HSA-211733;Reactome: R-HSA-162588;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5684264;Reactome: R-HSA-2644606;Reactome: R-HSA-5632684;Reactome: R-HSA-209560;Reactome: R-HSA-5610780;Reactome: R-HSA-1253288;Reactome: R-HSA-5655862;Reactome: R-HSA-201681;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-917937;Reactome: R-HSA-168928;Reactome: R-HSA-75815;Reactome: R-HSA-1236382;Reactome: R-HSA-174048;Reactome: R-HSA-5693565;Reactome: R-HSA-901032;Reactome: R-HSA-3769402;Reactome: R-HSA-8856825;Reactome: R-HSA-5205685;Reactome: R-HSA-5696400;Reactome: R-HSA-209543;Reactome: R-HSA-5610783;Reactome: R-HSA-156827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-2122947;Reactome: R-HSA-9613829;Reactome: R-HSA-69017;Reactome: R-HSA-9636383;Reactome: R-HSA-5654732;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-2559585;Reactome: R-HSA-445989;Reactome: R-HSA-9633012;Reactome: R-HSA-8939236;Reactome: R-HSA-5689896;Reactome: R-HSA-937041;Reactome: R-HSA-72764;Reactome: R-HSA-5668541;Reactome: R-HSA-5357956;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-9013973;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-937039;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-349425;Reactome: R-HSA-2565942;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-168927;Reactome: R-HSA-5654727;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8863795;Reactome: R-HSA-975163;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-912631;Reactome: R-HSA-400253;Reactome: R-HSA-202424;Reactome: R-HSA-72706;Reactome: R-HSA-5676590;Reactome: R-HSA-1295596;Reactome: R-HSA-69481;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-975110;Reactome: R-HSA-5675482;Reactome: R-HSA-5610785;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-205043;Reactome: R-HSA-5678895;Reactome: R-HSA-4641263;Reactome: R-HSA-936440;Reactome: R-HSA-175474;Reactome: R-HSA-450321;Reactome: R-HSA-2173795;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339;Reactome: R-HSA-9033241;Reactome: R-HSA-69541;Reactome: R-HSA-5696394;Reactome: R-HSA-8856828;Reactome: R-HSA-936964;Reactome: R-HSA-2173788;Reactome: R-HSA-5654726;Reactome: R-HSA-110314 "Translesion Synthesis by POLH";"Regulation of RUNX3 expression and activity";"Stimuli-sensing channels";"Fanconi Anemia Pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Processing of DNA double-strand break ends";"Endosomal Sorting Complex Required For Transport (ESCRT)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Metalloprotease DUBs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Translesion synthesis by POLI";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Selenocysteine synthesis";"IRAK2 mediated activation of TAK1 complex";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of TNFR1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"Dual incision in TC-NER";"APC/C:Cdc20 mediated degradation of Securin";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxidative Stress Induced Senescence";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Alpha-protein kinase 1 signaling pathway";"Formation of TC-NER Pre-Incision Complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"ISG15 antiviral mechanism";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of FGFR4 signaling";"Vpu mediated degradation of CD4";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"Gap-filling DNA repair synthesis and ligation in GG-NER";"FCERI mediated NF-kB activation";"Regulation of TP53 Activity through Phosphorylation";"Peptide chain elongation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"NOD1/2 Signaling Pathway";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Myoclonic epilepsy of Lafora";"Josephin domain DUBs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Late endosomal microautophagy";"Activation of NF-kappaB in B cells";"Regulation of innate immune responses to cytosolic DNA";"InlA-mediated entry of Listeria monocytogenes into host cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Activity through Methylation";"activated TAK1 mediates p38 MAPK activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Budding and maturation of HIV virion";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Hedgehog 'on' state";"NF-kB is activated and signals survival";"Degradation of GLI1 by the proteasome";"Downregulation of ERBB4 signaling";"Translesion synthesis by POLK";"TCF dependent signaling in response to WNT";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Iron uptake and transport";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Ubiquitin-dependent degradation of Cyclin D";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Cyclin B";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ER Quality Control Compartment (ERQC)";"Deactivation of the beta-catenin transactivating complex";"Cargo recognition for clathrin-mediated endocytosis";"Pink/Parkin Mediated Mitophagy";"Dual Incision in GG-NER";"p75NTR recruits signalling complexes";"Degradation of GLI2 by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NOTCH1 Intracellular Domain Regulates Transcription";"Chaperone Mediated Autophagy";"CDK-mediated phosphorylation and removal of Cdc6";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of FGFR3 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oncogene Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ovarian tumor domain proteases";"IKK complex recruitment mediated by RIP1";"Eukaryotic Translation Termination";"TNFR2 non-canonical NF-kB pathway";"TNFR1-induced NFkappaB signaling pathway";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1-dependent activation of IRF3/IRF7";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IRAK1 recruits IKK complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"TICAM1, RIP1-mediated IKK complex recruitment";"Negative regulation of FGFR2 signaling";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Neddylation";"UCH proteinases";"Regulation of signaling by CBL";"Circadian Clock";"Downstream TCR signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NIK-->noncanonical NF-kB signaling";"Spry regulation of FGF signaling";"G2/M Checkpoints";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Glycogen synthesis";"ABC-family proteins mediated transport";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of necroptotic cell death";"GLI3 is processed to GLI3R by the proteasome";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"NRIF signals cell death from the nucleus";"Defective CFTR causes cystic fibrosis";"Regulation of FZD by ubiquitination";"Negative regulators of DDX58/IFIH1 signaling";"Assembly Of The HIV Virion";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Peroxisomal protein import";"Stabilization of p53";"DNA Damage Recognition in GG-NER";"Clathrin-mediated endocytosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR1 signaling";"Recognition of DNA damage by PCNA-containing replication complex" XP_037286521.1 7 MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis" XP_037277787.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037285930.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037284446.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_037286542.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037270787.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037283362.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037289250.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037277063.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_037281920.1 3 KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" XP_037274654.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_037282623.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_037278703.1 9 MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation" XP_037287099.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037268731.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281792.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_037270646.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037289708.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037287413.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037276369.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037281887.1 10 KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis" XP_037275714.1 18 MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728 "Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle" XP_037286231.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_037274013.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037269058.1 56 Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-195253 "TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"UCH proteinases";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex" XP_037286114.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037283273.1 8 MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461 "Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P" XP_037291991.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037284686.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037291129.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037286644.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_037277463.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037269141.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037290013.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_037275678.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037290238.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037291789.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037268494.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037281690.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_037269518.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037283425.1 6 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2 "Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis" XP_037268918.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-877300 "Interferon alpha/beta signaling";"Interferon gamma signaling" XP_037273631.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-381340 "Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_037287317.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037274573.1 12 Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780 "RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation" XP_037277654.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037279326.1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_037276060.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037286380.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037291589.1 5 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding" XP_037270053.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037278509.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037268171.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037277203.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037278892.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037280801.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_037285258.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037280830.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037288196.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-9022692 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity" XP_037285966.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037283552.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037288557.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_037274849.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_037280526.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" XP_037271858.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037281400.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_037277704.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037272071.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037284712.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037288151.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recycling pathway of L1";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_037280788.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA" XP_037282782.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037286879.1 15 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2559582 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)" XP_037278510.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037284372.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_037284525.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_037292110.1 4 MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;MetaCyc: PWY-5030;Reactome: R-HSA-70921 "L-histidine degradation II";"Histidine metabolism";"L-histidine degradation III";"Histidine catabolism" XP_037285284.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037273496.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269320.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037271976.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037271706.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037274392.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-1234158 "Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of gene expression by Hypoxia-inducible Factor" XP_037278736.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037279574.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037288381.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037278714.1 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_037271191.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037268262.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037286991.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037278950.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037275002.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037282792.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530 "RAF/MAP kinase cascade";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_037281039.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037286228.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037271327.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex" XP_037287762.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037291835.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037268021.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate" XP_037286075.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037270032.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-264870 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Nephrin family interactions";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins" XP_037273743.1 17 KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Fanconi Anemia Pathway";"mTOR signaling pathway";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"PI3K-Akt signaling pathway" XP_037274307.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220 "Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins" XP_037277732.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_037282542.1 24 Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5617833 "HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Cilium Assembly" XP_037291784.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_037279244.1 6 MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_037283417.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037277246.1 1 Reactome: R-HSA-6787639 "GDP-fucose biosynthesis" XP_037279653.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037268275.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_037280746.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037278375.1 17 Reactome: R-HSA-75035;Reactome: R-HSA-176187;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of ATR in response to replication stress";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_037269177.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_037287639.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037279541.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037274401.1 3 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037291393.1 18 MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037274363.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-75815 "Neddylation";"UCH proteinases";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D" XP_037278281.1 12 Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-977225 "Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation" XP_037277187.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_037291027.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037288361.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_037270029.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Nephrin family interactions";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_037288450.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8866423 "Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL clearance";"Retinoid metabolism and transport";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"VLDL assembly" XP_037288382.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037278812.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037282828.1 6 KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-5514;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037288499.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037289704.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037271052.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037289248.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037287495.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037291111.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037286596.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_037272962.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424 "FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling" XP_037282819.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037281875.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037277412.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037278219.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037277682.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_037283819.1 1 Reactome: R-HSA-5687128 "MAPK6/MAPK4 signaling" XP_037277796.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037269180.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_037279169.1 3 Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_037285431.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037271260.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037281972.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037279109.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037278848.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037289987.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037288109.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037274179.1 9 KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-196780;MetaCyc: PWY-6146 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism" XP_037277420.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037288794.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037287278.1 1 Reactome: R-HSA-166208 "mTORC1-mediated signalling" XP_037280853.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037269499.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037288600.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_037286459.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_037276837.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597 "Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events" XP_037269415.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_037285641.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037279932.1 13 MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00260+5.4.2.12;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+5.4.2.12;MetaCyc: PWY-2221;MetaCyc: PWY-7124;KEGG: 00680+5.4.2.12;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycine, serine and threonine metabolism";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Superpathway of glucose and xylose degradation" XP_037275185.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037273244.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037279439.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037288876.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_037281246.1 14 Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Dual Incision in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_037291156.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269457.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037275161.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037287091.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037289497.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037274234.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037275512.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037284246.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_037283487.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037277512.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037286674.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037289060.1 32 Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75953 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation" XP_037283449.1 16 MetaCyc: PWY-5484;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-1622;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Methane metabolism";"Entner-Doudoroff pathway I";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation" XP_037290744.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_037286635.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862 "PPARA activates gene expression";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"RORA activates gene expression";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037275519.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_037285262.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037288655.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037288882.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1442490;Reactome: R-HSA-1592389 "Degradation of the extracellular matrix";"Collagen degradation";"Activation of Matrix Metalloproteinases" XP_037284892.1 19 MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7220 "Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_037275518.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037271664.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037276995.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037283879.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_037281529.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_037269174.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037275693.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037268549.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037283063.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037276568.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037282716.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037274286.1 7 MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-31;Reactome: R-HSA-70635;MetaCyc: PWY-46 "Urea cycle";"Arginine biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Urea cycle";"Putrescine biosynthesis III" XP_037279840.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037277417.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037289778.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037289122.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037271025.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_037282976.1 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037281214.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037280969.1 33 Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271 "SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus" XP_037268273.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" XP_037288933.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037277183.1 15 Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154 "APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin" XP_037271433.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037278261.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037280936.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation" XP_037288016.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_037291227.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037282624.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA" XP_037286516.1 17 Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167200;KEGG: 04658+3.1.3.16 "Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Th1 and Th2 cell differentiation" XP_037279785.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037275670.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037272897.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037274851.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_037268187.1 11 MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation" XP_037271969.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037277561.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_037277554.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_037268462.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037274222.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_037287584.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037280570.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037276126.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037268931.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037278997.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278834.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037283837.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037290561.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037285210.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037268739.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037288211.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;Reactome: R-HSA-1660662 "Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism" XP_037270441.1 14 KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_037283323.1 9 MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037289473.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_037276874.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037278829.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_037268082.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_037284714.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037282561.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037278055.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037286353.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037278603.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037289465.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037274856.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037271516.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_037287376.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037274402.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_037271687.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781 "HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression" XP_037275669.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_037272003.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-2559582 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)" XP_037271681.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_037272388.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037288124.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037279248.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_037284459.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037283656.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037284359.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-195253 "SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex" XP_037269797.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037282551.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037271544.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037268029.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037274207.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037289770.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037281642.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_037269607.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_037281006.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037279607.1 18 Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482925 "Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG" XP_037281932.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037291139.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037284753.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037280792.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037291580.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037271495.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037282443.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037268635.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037291532.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_037268811.1 8 KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-5154;MetaCyc: PWY-4983;MetaCyc: PWY-5;MetaCyc: PWY-7400;MetaCyc: PWY-4984 "Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle" XP_037277038.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037288451.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037269030.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037270882.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_037277052.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation" XP_037282627.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_037271198.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037278946.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037276334.1 6 KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037276747.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399 "Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_037288323.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037283095.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037283249.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037274347.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037291658.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037285259.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037278551.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037271024.1 6 MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7395 "N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation" XP_037274206.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism" XP_037275541.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271126.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037280664.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037292018.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Neddylation";"UCH proteinases";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins" XP_037283060.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037278920.1 8 MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_037274837.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037284379.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037276166.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037280935.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037268186.1 11 KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545 "Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037268461.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-2151201 "RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis" XP_037292145.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037287992.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037279098.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037278670.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037272986.1 6 KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" XP_037279415.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037290876.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037280527.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037281783.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037283222.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_037274900.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037268195.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state" XP_037273380.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_037271980.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_037286258.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037286718.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_037290471.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037282224.1 5 Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-9020702 "p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling" XP_037283568.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037281003.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037291453.1 4 MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation" XP_037273977.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037278382.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037282915.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_037274266.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037287410.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037283294.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037281878.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037271822.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" XP_037272149.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_037279446.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037290986.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_037269116.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037292090.1 3 Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807 "Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling" XP_037291013.1 12 Reactome: R-HSA-202733;Reactome: R-HSA-159740;Reactome: R-HSA-456926;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-977606;Reactome: R-HSA-140837;Reactome: R-HSA-159782;Reactome: R-HSA-76009;Reactome: R-HSA-381426;Reactome: R-HSA-159763;Reactome: R-HSA-140875 "Cell surface interactions at the vascular wall";"Gamma-carboxylation of protein precursors";"Thrombin signalling through proteinase activated receptors (PARs)";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Regulation of Complement cascade";"Intrinsic Pathway of Fibrin Clot Formation";"Removal of aminoterminal propeptides from gamma-carboxylated proteins";"Platelet Aggregation (Plug Formation)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus";"Common Pathway of Fibrin Clot Formation" XP_037289765.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037277523.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037290735.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590 "Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling" XP_037282918.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037289070.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037287638.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037291526.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037287679.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037278248.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037282974.1 10 Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664 "Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation" XP_037273962.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037285890.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037282628.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_037277387.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_037285387.1 4 MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_037287277.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037288950.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054 "HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA" XP_037287365.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128 "Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling" XP_037268162.1 27 Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-111367;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-159227;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-159231;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-6807505;Reactome: R-HSA-72187;Reactome: R-HSA-167200;Reactome: R-HSA-77595;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-77588;Reactome: R-HSA-674695;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-8851708 "mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA polymerase II transcribes snRNA genes";"mRNA 3'-end processing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM" XP_037287758.1 3 KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669 "Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_037278625.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037287547.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037274908.1 12 KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-6527;MetaCyc: PWY-3801;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis" XP_037287871.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037286962.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_037290154.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_037272337.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_037284310.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037291344.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037290602.1 6 MetaCyc: PWY-6609;KEGG: 00983+2.4.2.8;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6620;MetaCyc: PWY-6599;MetaCyc: PWY-6610 "Adenine and adenosine salvage III";"Drug metabolism - other enzymes";"Purine metabolism";"Guanine and guanosine salvage";"Guanine and guanosine salvage II";"Adenine salvage" XP_037289526.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037289002.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037290010.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation" XP_037277579.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_037283415.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037280264.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037272953.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413 "SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression" XP_037274151.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling" XP_037269033.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_037292081.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037287991.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037271192.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037278502.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037287267.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037278725.1 4 KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_037287027.1 5 KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;MetaCyc: PWY-4361;Reactome: R-HSA-111458 "Cysteine and methionine metabolism";"Methionine salvage pathway";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome" XP_037277402.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_037272047.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037285533.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037270913.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation" XP_037273963.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037288989.1 6 KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037289042.1 2 Reactome: R-HSA-418346;Reactome: R-HSA-139853 "Platelet homeostasis";"Elevation of cytosolic Ca2+ levels" XP_037280770.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_037270720.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037285865.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037285534.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_037286734.1 5 KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Stachyose degradation" XP_037291163.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037282774.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037269204.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037290354.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037291173.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037288288.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037278430.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_037268475.1 11 Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037282968.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037288552.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037269916.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_037284108.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037286491.1 9 MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2 "Ammonia assimilation cycle II";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism" XP_037271623.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-877300 "Interferon alpha/beta signaling";"Interferon gamma signaling" XP_037271113.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037280983.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_037287141.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037285933.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037285836.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037278905.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037282954.1 12 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-381038 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes" XP_037287390.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037285983.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037271136.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037288400.1 7 MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037290097.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037272179.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_037281621.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037270626.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037283535.1 17 Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-74259 "Purine salvage";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism" XP_037273555.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037279031.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037271186.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine" XP_037289189.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037287905.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037275465.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037271194.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037286905.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037282121.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037278511.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037273666.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037275840.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037271148.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_037279325.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110373 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_037269378.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_037280501.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037275267.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037270080.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037288121.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037283597.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037275885.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037268172.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037281853.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128 "Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling" XP_037290760.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037268426.1 5 Reactome: R-HSA-446388;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-8964616;Reactome: R-HSA-194840 "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"G beta:gamma signalling through CDC42";"Rho GTPase cycle" XP_037281630.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037290049.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037281051.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037289231.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_037278070.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037287568.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037269045.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037289429.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037276459.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_037283901.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037272025.1 30 Reactome: R-HSA-6804759;KEGG: 04714+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-8876198;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-111447;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-69656;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8941332;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;Reactome: R-HSA-9614399;Reactome: R-HSA-199418;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-211163;Reactome: R-HSA-198323 "Regulation of TP53 Activity through Association with Co-factors";"Thermogenesis";"CTLA4 inhibitory signaling";"RAB GEFs exchange GTP for GDP on RABs";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Acetylation";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Activation of BAD and translocation to mitochondria";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Relaxin signaling pathway";"RUNX2 regulates genes involved in cell migration";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"Regulation of localization of FOXO transcription factors";"Negative regulation of the PI3K/AKT network";"Human papillomavirus infection";"AKT phosphorylates targets in the nucleus";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the cytosol" XP_037287651.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037278974.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_037272882.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037289312.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037289959.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037274190.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037269989.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287759.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037283640.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037288678.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" XP_037270553.1 33 Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9609690 "Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events" XP_037278301.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037282537.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037281906.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037280987.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037277545.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037277770.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037288686.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" XP_037285859.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037289143.1 8 MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)" XP_037289132.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2979096 "Amyloid fiber formation";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_037281550.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037286967.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_037273253.1 1 Reactome: R-HSA-193670 "p75NTR negatively regulates cell cycle via SC1" XP_037285034.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037281005.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037271496.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037275963.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037288626.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037278838.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_037276151.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037277004.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037283671.1 12 Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events" XP_037268473.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans" XP_037274113.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037282592.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037275384.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-196025 "Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions" XP_037288852.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037273554.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037275132.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_037272315.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037284180.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037291816.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_037274774.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_037283769.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037282844.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037284511.1 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037292016.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_037284603.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037271185.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA" XP_037290269.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_037269346.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037282884.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037288629.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037281343.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037277506.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037287381.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037287315.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037271682.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" XP_037277158.1 5 MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1 "Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation" XP_037274884.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037277082.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037285297.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_037279542.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037291961.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037276167.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037268782.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287564.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037278529.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037285826.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037282796.1 10 MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051 "Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I" XP_037270609.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269117.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_037282421.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037268249.1 33 Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-69656;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167200 "Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_037274403.1 5 KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_037277152.1 3 Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037273904.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7822 "Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)" XP_037287174.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037280744.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037289683.1 8 MetaCyc: PWY-7181;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5 "Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_037287273.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;MetaCyc: PWY-7511 "Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination" XP_037287012.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037280058.1 10 MetaCyc: PWY-5844;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5890;MetaCyc: PWY-5895;MetaCyc: PWY-5891 "Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis" XP_037285972.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037283908.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_037282126.1 16 MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.4;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5749;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism" XP_037269497.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037281299.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037291290.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells" XP_037289208.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037272384.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037287581.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037289407.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037290221.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_037271375.1 6 MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)" XP_037281577.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037271320.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_037289856.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037281809.1 4 Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017 "Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_037274461.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037290805.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037284630.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037283084.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037284897.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037281922.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037268170.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037281173.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037282780.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_037281982.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037283540.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_037289462.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037292114.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation" XP_037285563.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037274963.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037271149.1 4 KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_037288122.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037288916.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037271021.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-933541 "TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation" XP_037269621.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037277426.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037271597.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037277505.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_037286934.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_037283416.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037269322.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037273240.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_037287098.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037279147.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_037286241.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037277738.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_037286876.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037291817.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_037291212.1 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" XP_037272237.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037279117.1 4 KEGG: 00500+3.1.3.9;KEGG: 00010+3.1.3.9;KEGG: 00052+3.1.3.9;Reactome: R-HSA-70263 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Gluconeogenesis" XP_037268510.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037283247.1 4 Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_037279186.1 12 MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00280+5.1.99.1;MetaCyc: PWY-7854;MetaCyc: PWY-5741;KEGG: 00630+5.1.99.1;KEGG: 00640+5.1.99.1;KEGG: 00720+5.1.99.1;MetaCyc: PWY-8086;Reactome: R-HSA-71032;MetaCyc: PWY-5743;MetaCyc: PWY-5789 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Valine, leucine and isoleucine degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Ethylmalonyl-coa pathway";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propionyl-CoA catabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_037288551.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037275000.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037276096.1 7 KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111 "Geraniol degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies" XP_037268657.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037275704.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037280646.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037275883.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037270133.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037279061.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037281198.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037275167.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037273497.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603 "Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Neddylation";"UCH proteinases" XP_037281213.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_037279178.1 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_037286794.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_037286497.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Neddylation";"UCH proteinases";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins" XP_037278498.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037283279.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037285362.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions" XP_037279912.1 5 Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037292140.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037290571.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037279979.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" XP_037291269.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling" XP_037282876.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037289055.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037290405.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037291084.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037279188.1 17 Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-983168 "Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037287436.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198 "Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis" XP_037284416.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_037292012.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702 "UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling" XP_037269851.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037283862.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037271103.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037290506.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037283816.1 1 Reactome: R-HSA-5687128 "MAPK6/MAPK4 signaling" XP_037281370.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-383280 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_037285151.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037275647.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037281743.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037282646.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_037282950.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037279434.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037284458.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037282747.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037282340.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037280806.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037272174.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"Folate biosynthesis" XP_037285938.1 20 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V" XP_037284193.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037278655.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037289757.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037268148.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037279051.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037283637.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037275654.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037287602.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037289066.1 10 Reactome: R-HSA-916853;MetaCyc: PWY-5022;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19 "Degradation of GABA";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"Butanoate metabolism";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"beta-Alanine metabolism" XP_037288549.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037291823.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037282080.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037285381.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037284423.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037292096.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037282444.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037292147.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037273782.1 5 Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037281931.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037280982.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037283841.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037292158.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037284808.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037285732.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037275395.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037279594.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037281952.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_037285447.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037280305.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_037281960.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_037271342.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037279471.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037269143.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037282949.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037290123.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037278384.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037273031.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-977606;Reactome: R-HSA-375276;Reactome: R-HSA-174577 "G alpha (i) signalling events";"Regulation of Complement cascade";"Peptide ligand-binding receptors";"Activation of C3 and C5" XP_037287560.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_037272298.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037269256.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037278063.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037268514.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037282288.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037279059.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037275134.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037289793.1 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_037272182.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion" XP_037279710.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037271805.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037281229.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037280101.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037271312.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037273665.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037270527.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837 "Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation" XP_037288512.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_037268707.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_037274441.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037271725.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037286655.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)" XP_037269414.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996 "Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_037288837.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_037284471.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037273546.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_037290595.1 6 MetaCyc: PWY-6599;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6609;KEGG: 00983+2.4.2.8;MetaCyc: PWY-6620 "Guanine and guanosine salvage II";"Adenine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Drug metabolism - other enzymes";"Guanine and guanosine salvage" XP_037287142.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037289908.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037291207.1 3 Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import" XP_037270402.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037270235.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching" XP_037275069.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_037283371.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037277293.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037268857.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_037284576.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037289726.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037279851.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_037282433.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037275387.1 16 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-196025;Reactome: R-HSA-5099900 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"Gap junction degradation";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4" XP_037286252.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037281633.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037290932.1 4 MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism" XP_037291997.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037286510.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037269620.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037281784.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_037274970.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037289109.1 18 Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6790901 "Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol" XP_037281655.1 7 MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205 "Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes" XP_037282908.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037278155.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_037270335.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_037269604.1 5 Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037280310.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037272628.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037281281.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037281978.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037275149.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037277347.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037283040.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037288364.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_037289822.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_037282818.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037281557.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037277358.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037290008.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_037281641.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Collagen degradation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"TNF signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037283795.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037271480.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-983168 "Protein ubiquitination";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037276365.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037291905.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_037285383.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_037286489.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037282942.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037279791.1 2 MetaCyc: PWY-7286;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_037278566.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037292132.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037291639.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037283683.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037278843.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_037284601.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037268063.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037285978.1 13 MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037284997.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037271735.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037284245.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037271384.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037277733.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037288152.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037271669.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281090.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037289715.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037276317.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037286818.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037283068.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037272120.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling" XP_037281371.1 5 MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism" XP_037279853.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_037285323.1 11 MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42 "TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes" XP_037277413.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037282948.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_037280244.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037270812.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037282941.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037285593.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-909733 "Interferon gamma signaling";"Interferon alpha/beta signaling" XP_037278889.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_037286921.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-168276 "tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways" XP_037283563.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037284702.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037287496.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037269467.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702 "UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling" XP_037277568.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037280314.1 4 Reactome: R-HSA-156582;KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00633+2.3.1.5 "Acetylation";"Caffeine metabolism";"Drug metabolism - other enzymes";"Nitrotoluene degradation" XP_037288740.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638 "tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins" XP_037284160.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037273544.1 33 Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-180910 "HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs" XP_037268729.1 12 MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I" XP_037272910.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037277854.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling" XP_037286152.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_037271683.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_037284468.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037286066.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037289664.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037278846.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037283213.1 56 Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-2467813 "Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids" XP_037291677.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037271344.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037289719.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037270175.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037284457.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037276990.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-5689880 "Methylation";"Ub-specific processing proteases" XP_037272423.1 179 Reactome: R-HSA-9615710;Reactome: R-HSA-1169091;Reactome: R-HSA-6807004;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-179409;Reactome: R-HSA-6804760;Reactome: R-HSA-450302;Reactome: R-HSA-8876493;Reactome: R-HSA-3134975;Reactome: R-HSA-2173791;Reactome: R-HSA-3785653;Reactome: R-HSA-168638;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-975957;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-5689877;Reactome: R-HSA-5610780;Reactome: R-HSA-209560;Reactome: R-HSA-1253288;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-75815;Reactome: R-HSA-168928;Reactome: R-HSA-917937;Reactome: R-HSA-201681;Reactome: R-HSA-5655862;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5684264;Reactome: R-HSA-162588;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2408557;Reactome: R-HSA-937042;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-6782135;Reactome: R-HSA-174154;Reactome: R-HSA-8866652;Reactome: R-HSA-174184;Reactome: R-HSA-2559580;Reactome: R-HSA-2979096;Reactome: R-HSA-5357905;Reactome: R-HSA-937072;Reactome: R-HSA-8875360;Reactome: R-HSA-975144;Reactome: R-HSA-5693607;Reactome: R-HSA-917729;Reactome: R-HSA-110320;Reactome: R-HSA-8941858;Reactome: R-HSA-6783310;Reactome: R-HSA-2672351;Reactome: R-HSA-5689901;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5656121;Reactome: R-HSA-2173796;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5696397;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-8849469;Reactome: R-HSA-156902;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-1169408;Reactome: R-HSA-6791226;Reactome: R-HSA-5654733;Reactome: R-HSA-9645460;Reactome: R-HSA-6781823;Reactome: R-HSA-5675482;Reactome: R-HSA-5610785;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-975110;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-5654727;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-8863795;Reactome: R-HSA-975163;Reactome: R-HSA-72706;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-912631;Reactome: R-HSA-400253;Reactome: R-HSA-202424;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339;Reactome: R-HSA-450321;Reactome: R-HSA-175474;Reactome: R-HSA-2173795;Reactome: R-HSA-936964;Reactome: R-HSA-8856828;Reactome: R-HSA-5696394;Reactome: R-HSA-2173788;Reactome: R-HSA-5654726;Reactome: R-HSA-110314;Reactome: R-HSA-9033241;Reactome: R-HSA-69541;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-4641263;Reactome: R-HSA-936440;Reactome: R-HSA-174113;Reactome: R-HSA-205043;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-9636383;Reactome: R-HSA-5654732;Reactome: R-HSA-2122947;Reactome: R-HSA-9613829;Reactome: R-HSA-2559585;Reactome: R-HSA-450408;Reactome: R-HSA-445989;Reactome: R-HSA-901032;Reactome: R-HSA-3769402;Reactome: R-HSA-1236382;Reactome: R-HSA-174048;Reactome: R-HSA-5693565;Reactome: R-HSA-5610783;Reactome: R-HSA-156827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-5205685;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-209543;Reactome: R-HSA-2565942;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-937039;Reactome: R-HSA-6781827;Reactome: R-HSA-349425;Reactome: R-HSA-8948747;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-168927;Reactome: R-HSA-5357956;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-5689896;Reactome: R-HSA-9633012;Reactome: R-HSA-937041;Reactome: R-HSA-72764;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-9013973;Reactome: R-HSA-69601 "Late endosomal microautophagy";"Activation of NF-kappaB in B cells";"Negative regulation of MET activity";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Activity through Methylation";"activated TAK1 mediates p38 MAPK activation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of innate immune responses to cytosolic DNA";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Myoclonic epilepsy of Lafora";"NOD1/2 Signaling Pathway";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs";"Degradation of GLI1 by the proteasome";"NF-kB is activated and signals survival";"Downregulation of ERBB4 signaling";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ubiquitin-dependent degradation of Cyclin D";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Iron uptake and transport";"TCF dependent signaling in response to WNT";"Translesion synthesis by POLK";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Budding and maturation of HIV virion";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Selenocysteine synthesis";"IRAK2 mediated activation of TAK1 complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"Dual incision in TC-NER";"APC/C:Cdc20 mediated degradation of Securin";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxidative Stress Induced Senescence";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of TNFR1 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Processing of DNA double-strand break ends";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Translesion Synthesis by POLH";"Regulation of RUNX3 expression and activity";"Fanconi Anemia Pathway";"Stimuli-sensing channels";"Metalloprotease DUBs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Translesion synthesis by POLI";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in GG-NER";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peptide chain elongation";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ISG15 antiviral mechanism";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of FGFR4 signaling";"Alpha-protein kinase 1 signaling pathway";"Formation of TC-NER Pre-Incision Complex";"Regulation of necroptotic cell death";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Glycogen synthesis";"ABC-family proteins mediated transport";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Neddylation";"UCH proteinases";"Negative regulation of FGFR2 signaling";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Spry regulation of FGF signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"Regulation of signaling by CBL";"Circadian Clock";"Downstream TCR signaling";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Assembly Of The HIV Virion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Downregulation of TGF-beta receptor signaling";"Negative regulation of FGFR1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Peroxisomal protein import";"Stabilization of p53";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"Regulation of FZD by ubiquitination";"Negative regulators of DDX58/IFIH1 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NRIF signals cell death from the nucleus";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of FGFR3 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Chaperone Mediated Autophagy";"Oncogene Induced Senescence";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"ER Quality Control Compartment (ERQC)";"Deactivation of the beta-catenin transactivating complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Cyclin B";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Degradation of GLI2 by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Pink/Parkin Mediated Mitophagy";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"p75NTR recruits signalling complexes";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"IRAK1 recruits IKK complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN localization";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"TICAM1, RIP1-mediated IKK complex recruitment";"TNFR1-induced NFkappaB signaling pathway";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ovarian tumor domain proteases";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"IKK complex recruitment mediated by RIP1";"Eukaryotic Translation Termination";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_037284536.1 20 MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II" XP_037287470.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037286900.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037288022.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037279042.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037269323.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037291066.1 5 Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037272173.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_037287938.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037281183.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-416476;Reactome: R-HSA-420499 "Neurexins and neuroligins";"G alpha (q) signalling events";"Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037283829.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037284357.1 5 MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_037271857.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037282432.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037279752.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037282049.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037283969.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037288081.1 13 KEGG: 00531+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sialic acid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B" XP_037270450.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037282549.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins" XP_037282923.1 9 KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037277215.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037280183.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037273935.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" XP_037285090.1 2 KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6 "Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism" XP_037287180.1 24 KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-114604;Reactome: R-HSA-165158;Reactome: R-HSA-354192;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"RSK activation";"GPVI-mediated activation cascade";"Activation of AKT2";"Integrin signaling";"Downstream TCR signaling";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Thermogenesis" XP_037271688.1 7 Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_037290361.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037286076.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037279479.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277815.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_037280340.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037287802.1 12 KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Macroautophagy";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway" XP_037291472.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037292048.1 4 MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_037289665.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037269573.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy" XP_037283010.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037269179.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_037278037.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037273029.1 4 Reactome: R-HSA-375276;Reactome: R-HSA-174577;Reactome: R-HSA-418594;Reactome: R-HSA-977606 "Peptide ligand-binding receptors";"Activation of C3 and C5";"G alpha (i) signalling events";"Regulation of Complement cascade" XP_037268019.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037271600.1 18 MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7220 "Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_037271588.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037269105.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037269596.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037268416.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_037276698.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells" XP_037281741.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_037288472.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037272339.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037270484.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037283706.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037283666.1 13 Reactome: R-HSA-2871809;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-2029485 "FCERI mediated Ca+2 mobilization";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"DAP12 signaling";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis" XP_037274257.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)" XP_037271244.1 4 KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_037288221.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037285942.1 20 Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728 "Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle" XP_037272300.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_037285166.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_037272151.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037278904.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037271985.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_037271804.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037287617.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1" XP_037277088.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037269252.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_037273690.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037278526.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-75815 "ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D" XP_037274417.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037270201.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037277091.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_037273050.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling" XP_037289327.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_037274184.1 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" XP_037290827.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037269104.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037277089.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes" XP_037287701.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037273716.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037285831.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037280824.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037269605.1 5 MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037281278.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037284978.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_037271278.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037277522.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037278556.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_037274839.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037278619.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037287910.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037280745.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037283711.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037271189.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway" XP_037275513.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277391.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287 "Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery" XP_037271901.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037283269.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037291486.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_037284698.1 9 Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-5649702 "Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_037284442.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745 "Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_037270324.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842 "4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II" XP_037273434.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037275649.1 11 MetaCyc: PWY-7124;MetaCyc: PWY-7254;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42 "Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes" XP_037278592.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037279774.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_037277617.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037277204.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037276952.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037282518.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037277247.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_037287566.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037278053.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037271449.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_037289794.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_037278853.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037290001.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037290333.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_037292152.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_037268815.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037269555.1 21 Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-168638;Reactome: R-HSA-5603029;Reactome: R-HSA-937041;Reactome: R-HSA-5684264;Reactome: R-HSA-5357956;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-5603027;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-168927;Reactome: R-HSA-937039;Reactome: R-HSA-933543;Reactome: R-HSA-2871837;Reactome: R-HSA-5602636;Reactome: R-HSA-1169091 "RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"NOD1/2 Signaling Pathway";"IkBA variant leads to EDA-ID";"IKK complex recruitment mediated by RIP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TNFR1-induced NFkappaB signaling pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1, RIP1-mediated IKK complex recruitment";"IRAK1 recruits IKK complex";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"FCERI mediated NF-kB activation";"IKBKB deficiency causes SCID";"Activation of NF-kappaB in B cells" XP_037271354.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_037283983.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037286583.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037269355.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037279166.1 14 KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;Reactome: R-HSA-499943;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-2261;MetaCyc: PWY-6842;MetaCyc: PWY-7533 "Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Interconversion of nucleotide di- and triphosphates";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis" XP_037271343.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037287957.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_037276131.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037279375.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_037274589.1 5 Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-111464 "Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_037281466.1 4 Reactome: R-HSA-70921;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5030;MetaCyc: PWY-5028 "Histidine catabolism";"Histidine metabolism";"L-histidine degradation III";"L-histidine degradation II" XP_037268310.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037291214.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_037287423.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-156590 "Peroxisomal protein import";"Glutathione conjugation" XP_037274638.1 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_037282172.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037268324.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037270460.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037284343.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037285731.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037281757.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287766.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037273293.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_037287765.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037277051.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism" XP_037271534.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037275673.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037274187.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037276933.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037269079.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037276687.1 17 Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-174414 "Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere" XP_037281294.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037283774.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037271722.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037274285.1 7 MetaCyc: PWY-6922;MetaCyc: PWY-31;Reactome: R-HSA-70635;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984 "L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Urea cycle";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Arginine biosynthesis";"Urea cycle" XP_037282959.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037292039.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_037277904.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037284366.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037268930.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037285886.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287749.1 6 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037280854.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037278394.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037270922.1 17 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_037274912.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_037272382.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037292103.1 2 Reactome: R-HSA-432040;Reactome: R-HSA-432047 "Vasopressin regulates renal water homeostasis via Aquaporins";"Passive transport by Aquaporins" XP_037282179.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037272992.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037269365.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3 "Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Arachidonic acid metabolism" XP_037282621.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037287869.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037274776.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037270077.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis" XP_037281199.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037276083.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037284406.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_037281583.1 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II" XP_037273394.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-917937;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-202424;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-68949 "Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Iron uptake and transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin" XP_037268277.1 11 MetaCyc: PWY-7560;MetaCyc: PWY-6383;MetaCyc: PWY-7524;MetaCyc: PWY-6859;MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-922 "Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I" XP_037271280.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037281884.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037278721.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037281433.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_037291249.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037289748.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037277718.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_037286965.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757 "Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Regulation of TP53 Degradation" XP_037270467.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037281099.1 8 Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-4608870;Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588 "Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation" XP_037292054.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037277334.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037289328.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_037279585.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_037291459.1 4 MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_037276773.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037281637.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037279962.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037270078.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_037279421.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037271996.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5467340 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex" XP_037285363.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_037280438.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037279082.1 52 Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-749476;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-1834949 "Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_037286421.1 7 MetaCyc: PWY-3841;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205 "Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription" XP_037271386.1 4 Reactome: R-HSA-375276;Reactome: R-HSA-174577;Reactome: R-HSA-418594;Reactome: R-HSA-977606 "Peptide ligand-binding receptors";"Activation of C3 and C5";"G alpha (i) signalling events";"Regulation of Complement cascade" XP_037289326.1 8 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)" XP_037281820.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037276971.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_037285557.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037278733.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037274456.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037273960.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037286426.1 8 Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2 "Amino acids regulate mTORC1";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Insulin receptor recycling";"Photosynthesis" XP_037286826.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037272492.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037289744.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037277443.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52 "Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis" XP_037288885.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037288326.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037281350.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037269559.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037283348.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037290468.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037270471.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_037286408.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway" XP_037270081.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037282803.1 11 MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-7185;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381 "Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)" XP_037280556.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037283662.1 6 MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Biotin metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency" XP_037286397.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037291821.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037272565.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037272950.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037285510.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037287892.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037287929.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-195253 "Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"UCH proteinases";"Neddylation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex" XP_037288213.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-7344 "Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_037282683.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037275062.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037285925.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-72086 "RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping" XP_037285889.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037283596.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037279161.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037282804.1 11 MetaCyc: PWY-7185;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6608 "UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III" XP_037269926.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037270015.1 8 MetaCyc: PWY-4983;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5154;Reactome: R-HSA-70635;KEGG: 00250+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-5 "Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis" XP_037282020.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037278558.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037281467.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037282056.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037279782.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037287342.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_037270030.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-6798695 "NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"Neutrophil degranulation" XP_037273003.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_037289953.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037268477.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_037276914.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037274898.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037284114.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037284689.1 8 KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4 "Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_037268417.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_037281396.1 13 KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-4061;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590 "Ascorbate and aldarate metabolism";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione conjugation" XP_037272670.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037280604.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037279746.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037279476.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037275157.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037280492.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037291891.1 11 MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675 "Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)" XP_037287709.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037286495.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037279329.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037279748.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037281091.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037287586.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_037282031.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037282323.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production" XP_037291781.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_037276916.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_037289638.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037272172.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037282085.1 1 MetaCyc: PWY-7883 "Anhydromuropeptides recycling II" XP_037282426.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037268122.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037278039.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037269975.1 40 KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7094;MetaCyc: PWY-6435;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5109;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-5177;MetaCyc: PWY-7216;MetaCyc: PWY-6583;MetaCyc: PWY-1361;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17 "Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"Methyl tert-butyl ether degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Benzoate degradation";"beta-Alanine metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation" XP_037289530.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_037283282.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037282515.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_037271143.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation" XP_037289759.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897 "Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes" XP_037291933.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037289061.1 32 Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167158 "Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex" XP_037278729.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037274246.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037289517.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_037271337.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037286810.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037269188.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037281167.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_037292133.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037288881.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037288319.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037284664.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_037277140.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295 "VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation" XP_037285048.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_037274875.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_037270529.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037290451.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037271532.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287636.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037290356.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037286912.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037272235.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_037271306.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037284350.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_037275830.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037277680.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_037283228.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037292000.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037277652.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_037272709.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037279546.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037287664.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037286486.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037288580.1 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_037271328.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_037284331.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" YP_008999532.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037272246.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037281872.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037285291.1 8 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2465910 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"MASTL Facilitates Mitotic Progression" XP_037277728.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" XP_037290061.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock" XP_037287176.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037279389.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037279134.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037277620.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037268347.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037276602.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037281137.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037278650.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_037280869.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism" XP_037284027.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037287770.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938 "Chylomicron remodeling";"Retinoid metabolism and transport";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL clearance";"VLDL assembly";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand" XP_037268664.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283815.1 1 Reactome: R-HSA-5687128 "MAPK6/MAPK4 signaling" XP_037286488.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_037287685.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037280205.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037270075.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037291316.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037276420.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037282951.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_037286005.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis" XP_037283713.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332 "Activation of AMPK downstream of NMDARs";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin" XP_037270296.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037286601.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_037277111.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_037292047.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_037283204.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Neddylation" XP_037268928.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037286317.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_037289213.1 42 Reactome: R-HSA-73728;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-912446;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-110330;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-606279;Reactome: R-HSA-5693565 "RNA Polymerase I Promoter Opening";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"Cleavage of the damaged purine";"Meiotic synapsis";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037282775.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037282997.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037290328.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037287182.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037280364.1 44 Reactome: R-HSA-74749;Reactome: R-HSA-6802948;Reactome: R-HSA-170968;Reactome: R-HSA-6802946;Reactome: R-HSA-5654727;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-3371453;Reactome: R-HSA-1295596;KEGG: 04150+2.7.11.24;Reactome: R-HSA-8939211;Reactome: R-HSA-5674499;Reactome: R-HSA-9627069;Reactome: R-HSA-6811558;Reactome: R-HSA-112409;Reactome: R-HSA-982772;Reactome: R-HSA-8940973;Reactome: R-HSA-5673001;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-5675221;Reactome: R-HSA-879415;Reactome: R-HSA-5663213;Reactome: R-HSA-5668599;Reactome: R-HSA-2029482;Reactome: R-HSA-2559585;Reactome: R-HSA-9649948;Reactome: R-HSA-2559580;Reactome: R-HSA-5674135;Reactome: R-HSA-2559582;Reactome: R-HSA-444257;Reactome: R-HSA-9634638;Reactome: R-HSA-6802952;Reactome: R-HSA-5654733;Reactome: R-HSA-9635465;Reactome: R-HSA-881907;Reactome: R-HSA-6802955;Reactome: R-HSA-198753;Reactome: R-HSA-445144;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-162658;Reactome: R-HSA-202670;Reactome: R-HSA-375165 "Signal attenuation";"Signaling by high-kinase activity BRAF mutants";"Frs2-mediated activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"Regulation of HSF1-mediated heat shock response";"Spry regulation of FGF signaling";"mTOR signaling pathway";"ESR-mediated signaling";"Negative feedback regulation of MAPK pathway";"Regulation of the apoptosome activity";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF-independent MAPK1/3 activation";"Growth hormone receptor signaling";"RUNX2 regulates osteoblast differentiation";"RAF/MAP kinase cascade";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate NADPH Oxidases";"Regulation of actin dynamics for phagocytic cup formation";"Oncogene Induced Senescence";"Signaling downstream of RAS mutants";"Oxidative Stress Induced Senescence";"MAP2K and MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"RSK activation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of FGFR4 signaling";"Suppression of apoptosis";"Gastrin-CREB signalling pathway via PKC and MAPK";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ERK/MAPK targets";"Signal transduction by L1";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"ERKs are inactivated";"NCAM signaling for neurite out-growth" XP_037282563.1 12 KEGG: 00630+6.4.1.3;KEGG: 00640+6.4.1.3;Reactome: R-HSA-3371599;MetaCyc: PWY-6728;MetaCyc: PWYG-321;KEGG: 00280+6.4.1.3;MetaCyc: PWY-7384;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-71032;KEGG: 00720+6.4.1.3;Reactome: R-HSA-196780 "Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Methylaspartate cycle";"";"Valine, leucine and isoleucine degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propionyl-CoA catabolism";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism" XP_037290007.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" XP_037268074.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_037278952.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037288991.1 6 MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism" XP_037285671.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_037287388.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_037276794.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037291014.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape" XP_037280748.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_037274081.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690 "HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HCMV Early Events" XP_037291441.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_037289392.1 10 KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003 "Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol" XP_037268006.1 7 MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-882 "GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_037291842.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037277419.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037277951.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_037281552.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037288957.1 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_037272710.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037286206.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037268965.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037277350.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037277397.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037283707.1 2 Reactome: R-HSA-977606;Reactome: R-HSA-174577 "Regulation of Complement cascade";"Activation of C3 and C5" XP_037288522.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037285772.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037269876.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271995.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358749 "Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated" XP_037291536.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037277355.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation" XP_037289385.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037268982.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037283388.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling" XP_037281869.1 5 MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_037271895.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037291755.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037281205.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037281077.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037283832.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037287093.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037274495.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037277418.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037271810.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_037291428.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037279616.1 4 MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558 "Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine" XP_037286785.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_037282799.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerolipid metabolism" XP_037278989.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_037287954.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037284153.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037277043.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037285899.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037282820.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037281903.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037286246.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037280608.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037290620.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037273903.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037292102.1 2 Reactome: R-HSA-432040;Reactome: R-HSA-432047 "Vasopressin regulates renal water homeostasis via Aquaporins";"Passive transport by Aquaporins" XP_037269592.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037276097.1 7 KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241;MetaCyc: PWY-5074 "Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Mevalonate degradation" XP_037271416.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037273871.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058 "Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_037285261.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037274358.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037273522.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_037287303.1 14 MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00670+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;Reactome: R-HSA-196757 "Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"One carbon pool by folate";"Photorespiration ";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"Cyanoamino acid metabolism";"Folate transformations I";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Metabolism of folate and pterines" XP_037286828.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037282666.1 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome" XP_037286827.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_037272919.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037271585.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037278990.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-163560;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Triglyceride catabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037271097.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037289167.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037289861.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037279761.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037278497.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037289496.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037280275.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037277473.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_037287112.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037269345.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037289277.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037276168.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037277775.1 30 Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2122947;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-2894862;Reactome: R-HSA-917937;Reactome: R-HSA-8854050 "SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"NOTCH1 Intracellular Domain Regulates Transcription";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Iron uptake and transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_037291818.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037290461.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_037285493.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_037271451.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037280739.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037278722.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_037269569.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037286848.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037270003.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037279643.1 3 Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426 "Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_037287552.1 10 MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;Reactome: R-HSA-1989781 "Mevalonate pathway III (archaea)";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression" XP_037287173.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_037277066.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037282797.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_037289063.1 32 Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-75953 "Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation" XP_037290181.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037269808.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" XP_037284148.1 5 KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis" XP_037272671.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037290358.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037288559.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037280198.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037284249.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037270532.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions" XP_037284962.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221 "Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway" XP_037287961.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037282281.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037289624.1 3 Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037277337.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037276818.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037277491.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037286584.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037276963.1 7 KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14 "Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_037277289.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism" XP_037288337.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037279937.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037281243.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037283414.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037273484.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037284726.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037282003.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5856;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5855 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_037284248.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_037291546.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_037272444.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_037286772.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037277429.1 24 Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"HCMV Early Events" XP_037282180.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037274225.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037283281.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037285330.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037284505.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_037281252.1 4 KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1 "Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_037270781.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24 "NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"mTOR signaling pathway" XP_037268058.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" XP_037273072.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_037270343.1 32 Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167243 "Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery" XP_037285288.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"MASTL Facilitates Mitotic Progression";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_037290148.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_037273719.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037282514.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037275128.1 14 MetaCyc: PWY-7039;Reactome: R-HSA-500657;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-4086398;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-416476;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043 "Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Ca2+ pathway";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events" XP_037291577.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037291109.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037274896.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells" XP_037277044.1 9 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-446353 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Cell-extracellular matrix interactions" XP_037270072.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037289907.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037291829.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037269594.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287820.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037289308.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_037283872.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037273139.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_037282883.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037287004.1 6 Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3 "Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_037287366.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_037280177.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037268587.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037284545.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037274156.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037271684.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_037283729.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037282096.1 4 MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism" XP_037288257.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037271382.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037272208.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037274101.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_037285155.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_037278628.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037276411.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037268056.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037271819.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" XP_037289491.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037279692.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037284620.1 5 Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35 "Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism" XP_037281217.1 7 Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_037281876.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037289461.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037268164.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits" XP_037269193.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037270483.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_037281587.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_037282125.1 16 KEGG: 00640+6.2.1.4;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5749;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403 "Propanoate metabolism";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)" XP_037278810.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037271356.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037289976.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037287168.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037291146.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037291433.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_037277497.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037282245.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037287520.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037275336.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037287260.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287426.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_037287643.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037272123.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037271400.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037272105.1 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037282580.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_037279086.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852 "Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Macroautophagy" XP_037280596.1 18 KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00020+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-204174;Reactome: R-HSA-71403;Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-70268;Reactome: R-HSA-70895;Reactome: R-HSA-6783984;KEGG: 00310+1.8.1.4;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-71064 "Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citric acid cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Branched-chain amino acid catabolism";"Glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism" XP_037283981.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037273722.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037273717.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037287921.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037279018.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037275614.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-9609690 "Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events" XP_037277189.1 5 MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)" XP_037286769.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037286645.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_037284548.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037288380.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037281230.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037270633.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037274336.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037269410.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037288639.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_037276726.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037282638.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037276888.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_037271549.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037291561.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037277684.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037281212.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110357 "POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1" XP_037288697.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037282196.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037287934.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497 "Chylomicron remodeling";"Retinoid metabolism and transport";"Chylomicron assembly";"Chylomicron clearance";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Post-translational protein phosphorylation";"VLDL assembly";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors" XP_037272785.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037287582.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037281699.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037272140.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_037269690.1 18 Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism" XP_037282500.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037281048.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037270503.1 33 Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5663220 "SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins" XP_037289713.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037286594.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_037288015.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_037287114.1 13 KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-7184;Reactome: R-HSA-74259;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7206 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation" XP_037289373.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_037289994.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037289509.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_037284229.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037282012.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_037271068.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037270519.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037283092.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_037271391.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037280102.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037272591.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037277901.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037278418.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037292003.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037279349.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037290200.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037281582.1 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II" XP_037274296.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_037282337.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037288537.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037272026.1 30 KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-198323;Reactome: R-HSA-211163;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-69656;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8941332;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1358803;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-392451;Reactome: R-HSA-8876198;Reactome: R-HSA-5674400;Reactome: R-HSA-6804759;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT phosphorylates targets in the cytosol";"AKT-mediated inactivation of FOXO1A";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Cyclin A:Cdk2-associated events at S phase entry";"Relaxin signaling pathway";"RUNX2 regulates genes involved in cell migration";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Acetylation";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Downregulation of ERBB2:ERBB3 signaling";"Human immunodeficiency virus 1 infection";"CTLA4 inhibitory signaling";"G beta:gamma signalling through PI3Kgamma";"RAB GEFs exchange GTP for GDP on RABs";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Activity through Association with Co-factors";"Thermogenesis" XP_037273250.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037289257.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037284906.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037288571.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037269265.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037269463.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" XP_037272783.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037279827.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_037274880.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_037292183.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037273824.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_037268216.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_037273887.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_037277277.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_037269832.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037281471.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_037268157.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation" XP_037289815.1 11 Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-912694;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-9008059;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-389948;Reactome: R-HSA-391160 "Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"Regulation of IFNA signaling";"PECAM1 interactions";"Platelet sensitization by LDL";"Interleukin-37 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"PD-1 signaling";"Signal regulatory protein family interactions" XP_037287974.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037289699.1 2 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" XP_037279052.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037270147.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037275750.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037278649.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_037279900.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037291110.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037271598.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037284281.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037278586.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037283979.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037289052.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037268072.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_037282259.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037286358.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037275841.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269810.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_037288148.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037288404.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037278004.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037274446.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037285255.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037277547.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_037286536.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037269976.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122 "Neutrophil degranulation";"WNT mediated activation of DVL";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037287364.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037278630.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037292122.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_037281119.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037291824.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037284822.1 40 Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5601884 "Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis" XP_037268919.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-877300 "Interferon alpha/beta signaling";"Interferon gamma signaling" XP_037269783.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037287290.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_037286475.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_037268497.1 2 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate" XP_037292142.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037279848.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037280245.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037283923.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096 "CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation" XP_037271537.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037289086.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037281034.1 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_037272369.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_037277810.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_037276319.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037287254.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8953750 "HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6" XP_037288845.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037279669.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037273821.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037269051.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037286617.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_037292052.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_037276452.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037274892.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_037277458.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176408 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase" XP_037283392.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037278311.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037271235.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037280232.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037271972.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_037276925.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037281838.1 42 KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7778;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7094;MetaCyc: PWY-6435;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-5109;MetaCyc: PWY-6883;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-7216;MetaCyc: PWY-5177;MetaCyc: PWY-1361;MetaCyc: PWY-6583;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00627+4.2.1.17 "Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Benzoate degradation";"beta-Alanine metabolism";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Tryptophan metabolism";"Lysine degradation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Aminobenzoate degradation" XP_037281341.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037274359.1 5 MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_037288855.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_037281659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037273870.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_037287444.1 5 Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938 "Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)" XP_037289724.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037270459.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269530.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037289864.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_037270963.1 3 Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581 "Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation" XP_037285931.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037283276.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-532668 "Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037273048.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-191859 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly" XP_037279777.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037273186.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037282011.1 4 KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247 "Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids" XP_037269988.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037270292.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037274006.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037285329.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037272389.1 9 Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324 "Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037269257.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_037282680.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" YP_008999531.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037276140.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_037269032.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037286968.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization" XP_037269358.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430 "Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling" XP_037285842.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037287662.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_037277616.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_037282726.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones" XP_037272110.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037276579.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037277480.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037282548.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870 "Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins" XP_037275137.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_037272937.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037289503.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037289707.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037277231.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037289703.1 2 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" XP_037287531.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037291200.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037285026.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037280942.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037283537.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_037284563.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037285274.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037280516.1 9 MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590 "4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Glutathione conjugation" XP_037280335.1 13 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation" XP_037287542.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670 "Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis" XP_037277531.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-180746 "SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Nuclear import of Rev protein" XP_037278939.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037284595.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_037281313.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037276310.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037273359.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037278695.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_037278944.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_037283221.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_037271567.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_037290321.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037287513.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_037276890.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037282993.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037281886.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6837 "Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" XP_037281923.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037283730.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037291653.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119 "Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_037273627.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037285663.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_037278336.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037280271.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037268084.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037277435.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037282805.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037287300.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269119.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499 "RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane" XP_037279146.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_037286751.1 5 KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation" XP_037288278.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037277360.1 18 MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6 "Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism" XP_037271473.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_037285862.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_037279506.1 5 KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937 "Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport" XP_037283263.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037268636.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037280345.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037269774.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037272763.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_037269332.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037289787.1 42 Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-2559582;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-5334118 "Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Senescence-Associated Secretory Phenotype (SASP)";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Cleavage of the damaged purine";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"DNA methylation" XP_037288827.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037270451.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037286886.1 3 Reactome: R-HSA-156581;KEGG: 00983+2.1.1.67;Reactome: R-HSA-5578995 "Methylation";"Drug metabolism - other enzymes";"Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)" XP_037278836.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037277507.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_037282605.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037287873.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037283488.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037283303.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037270596.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037272225.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037291183.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037269701.1 2 KEGG: 00240+3.6.1.12;Reactome: R-HSA-499943 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037283253.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037282816.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037291445.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037288330.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_037271355.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037271236.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_037278544.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_037271437.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2672351;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Stimuli-sensing channels";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway" XP_037278665.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037283718.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037286719.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037280681.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037278393.1 7 KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;MetaCyc: PWY-6471;MetaCyc: PWY-5265;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037273720.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037280045.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681 "Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Activation of SMO";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions" XP_037277956.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037285757.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_037274998.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037291790.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037270264.1 2 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "DNA methylation";"Cysteine and methionine metabolism" XP_037292040.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_037285686.1 28 Reactome: R-HSA-5693616;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-6783310;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-3371511 "Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"HSF1 activation" XP_037274376.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis" XP_037286710.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037288612.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037269097.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654 "Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037284186.1 29 Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-6782210 "RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037271261.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-7115 "3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_037289722.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037271596.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037279447.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037280709.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037268017.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037284401.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events" XP_037279381.1 6 KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723 "Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Rubisco shunt" XP_037289335.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037289082.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037283664.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037289760.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037292074.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037285982.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037290521.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037286959.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037275001.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037283512.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037274012.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037268306.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037273909.1 4 Reactome: R-HSA-204005;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295 "COPII-mediated vesicle transport";"Neutrophil degranulation";"Cargo concentration in the ER";"MHC class II antigen presentation" XP_037280787.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses" XP_037282773.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037289278.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037287987.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037286768.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_037277245.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037271177.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037271017.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037286722.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037268305.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037273521.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037289986.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037269187.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037281961.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" XP_037290217.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037269036.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037282223.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-209543 "Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes" XP_037291782.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_037278038.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037283413.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037274994.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_037274433.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037270465.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037288157.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037276183.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037281308.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037282536.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037276162.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_037289521.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_037281772.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037270051.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037289762.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459 "Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Meiotic synapsis";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037274529.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037287383.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037288452.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037281434.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037282657.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037289850.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037274020.1 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037274882.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_037272376.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import" XP_037289709.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037289252.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport" XP_037283990.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_037269455.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037274906.1 13 MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2 "Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes" XP_037276129.1 14 KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-4302 "Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)" XP_037268676.1 9 MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes" XP_037291798.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037284575.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_037280220.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037282173.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037280311.1 3 MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6782861 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_037285765.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_037287435.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_037277893.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037287302.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037287095.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037285952.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_037269076.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037279189.1 17 Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-8951664 "Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation" XP_037278735.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_037276612.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037286355.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037279767.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037268309.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037274424.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037287202.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Hedgehog 'off' state" XP_037276866.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037292010.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_037287140.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037280421.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037271897.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037268556.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281426.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-5610785 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome" XP_037292123.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_037279043.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037289072.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037292099.1 2 Reactome: R-HSA-432047;Reactome: R-HSA-432040 "Passive transport by Aquaporins";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037268089.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037291310.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037286225.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" XP_037274556.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037281914.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037278575.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037271994.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037271258.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037288912.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037273452.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037273319.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037282787.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037282960.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_037292151.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037283963.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037285260.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037279192.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744 "3-hydroxypropanoate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation" XP_037278371.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037276965.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037268083.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037280246.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037285405.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037287320.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs" XP_037275668.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion" XP_037272494.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation" XP_037281941.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037271307.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_037286273.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037289356.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_037269831.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037282286.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037290739.1 26 Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-1445148 "MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Recycling pathway of L1";"Cilium Assembly";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037284749.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037281877.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037281035.1 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_037283307.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037276936.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" XP_037273341.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037283822.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037277039.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037284871.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037282371.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037285003.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_037282887.1 29 Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-6781823 "RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex" XP_037284424.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037270058.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037278622.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037283558.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037270923.1 9 MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381 "Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)" XP_037277381.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037277927.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_037280798.1 11 KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_037289388.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037270624.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037276838.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037284485.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037277378.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037272137.1 182 Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5656121;Reactome: R-HSA-2173796;Reactome: R-HSA-5689901;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2672351;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-975144;Reactome: R-HSA-5693607;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-937072;Reactome: R-HSA-5357905;Reactome: R-HSA-2979096;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-2559580;Reactome: R-HSA-8866652;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-2894862;Reactome: R-HSA-6782135;Reactome: R-HSA-937042;Reactome: R-HSA-2691232;Reactome: R-HSA-2408557;Reactome: R-HSA-9645460;Reactome: R-HSA-6781823;Reactome: R-HSA-5654733;Reactome: R-HSA-6791226;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-1169408;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-156902;Reactome: R-HSA-8849469;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5696397;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-975957;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-3785653;Reactome: R-HSA-3134975;Reactome: R-HSA-8876493;Reactome: R-HSA-2173791;Reactome: R-HSA-6804760;Reactome: R-HSA-450302;Reactome: R-HSA-179409;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-6807004;Reactome: R-HSA-1169091;Reactome: R-HSA-9615710;Reactome: R-HSA-2644606;Reactome: R-HSA-5632684;Reactome: R-HSA-162588;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5684264;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-72695;Reactome: R-HSA-201681;Reactome: R-HSA-5655862;Reactome: R-HSA-168928;Reactome: R-HSA-917937;Reactome: R-HSA-75815;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-1253288;Reactome: R-HSA-209560;Reactome: R-HSA-5610780;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-156827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5693565;Reactome: R-HSA-174048;Reactome: R-HSA-1236382;Reactome: R-HSA-3769402;Reactome: R-HSA-901032;Reactome: R-HSA-450408;Reactome: R-HSA-2559585;Reactome: R-HSA-445989;Reactome: R-HSA-9613829;Reactome: R-HSA-2122947;Reactome: R-HSA-9636383;Reactome: R-HSA-174084;Reactome: R-HSA-5654732;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-9013973;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-937041;Reactome: R-HSA-72764;Reactome: R-HSA-5689896;Reactome: R-HSA-9633012;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5357956;Reactome: R-HSA-168927;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-8948747;Reactome: R-HSA-349425;Reactome: R-HSA-937039;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-2565942;Reactome: R-HSA-912631;Reactome: R-HSA-202424;Reactome: R-HSA-400253;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-72706;Reactome: R-HSA-5676590;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-975163;Reactome: R-HSA-5654727;Reactome: R-HSA-1236974;Reactome: R-HSA-72702;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-72649;Reactome: R-HSA-382556;Reactome: R-HSA-3322077;Reactome: R-HSA-975110;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-5675482;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-205043;Reactome: R-HSA-5678895;Reactome: R-HSA-936440;Reactome: R-HSA-4641263;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-182971;Reactome: R-HSA-9033241;Reactome: R-HSA-69541;Reactome: R-HSA-5654726;Reactome: R-HSA-2173788;Reactome: R-HSA-110314;Reactome: R-HSA-8856828;Reactome: R-HSA-936964;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-450321;Reactome: R-HSA-175474;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339 "CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Translesion synthesis by POLI";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Metalloprotease DUBs";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Stimuli-sensing channels";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Processing of DNA double-strand break ends";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TNFR1 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxidative Stress Induced Senescence";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Dual incision in TC-NER";"IRAK2 mediated activation of TAK1 complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Selenocysteine synthesis";"Alpha-protein kinase 1 signaling pathway";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of FGFR4 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"ISG15 antiviral mechanism";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Peptide chain elongation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Josephin domain DUBs";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"Myoclonic epilepsy of Lafora";"Regulation of innate immune responses to cytosolic DNA";"InlA-mediated entry of Listeria monocytogenes into host cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of TP53 Activity through Methylation";"activated TAK1 mediates p38 MAPK activation";"APC-Cdc20 mediated degradation of Nek2A";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Negative regulation of MET activity";"Activation of NF-kappaB in B cells";"Late endosomal microautophagy";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Hedgehog 'on' state";"Budding and maturation of HIV virion";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Formation of the ternary complex, and subsequently, the 43S complex";"TCF dependent signaling in response to WNT";"Translesion synthesis by POLK";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Iron uptake and transport";"Ubiquitin-dependent degradation of Cyclin D";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downregulation of ERBB4 signaling";"NF-kB is activated and signals survival";"Degradation of GLI1 by the proteasome";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"APC/C:Cdc20 mediated degradation of Cyclin B";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Deactivation of the beta-catenin transactivating complex";"ER Quality Control Compartment (ERQC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oncogene Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Chaperone Mediated Autophagy";"NOTCH1 Intracellular Domain Regulates Transcription";"Prevention of phagosomal-lysosomal fusion";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of FGFR3 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"IKK complex recruitment mediated by RIP1";"Eukaryotic Translation Termination";"Ovarian tumor domain proteases";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"TNFR1-induced NFkappaB signaling pathway";"TICAM1, RIP1-mediated IKK complex recruitment";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"Regulation of PTEN localization";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK1 recruits IKK complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of signaling by CBL";"Downstream TCR signaling";"Circadian Clock";"G2/M Checkpoints";"Spry regulation of FGF signaling";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR2 signaling";"ER-Phagosome pathway";"Ribosomal scanning and start codon recognition";"UCH proteinases";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Translation initiation complex formation";"ABC-family proteins mediated transport";"Glycogen synthesis";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of necroptotic cell death";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"NRIF signals cell death from the nucleus";"Defective CFTR causes cystic fibrosis";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of FZD by ubiquitination";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"EGFR downregulation";"Peroxisomal protein import";"Stabilization of p53";"Negative regulation of FGFR1 signaling";"Downregulation of TGF-beta receptor signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Clathrin-mediated endocytosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Assembly Of The HIV Virion";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane" XP_037269882.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037283439.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037268196.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037279237.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037279966.1 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" XP_037287973.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037281612.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037291357.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037278642.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037277878.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_037292181.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037271583.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037274585.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037270667.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037286215.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277606.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12 "Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism" XP_037287319.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037284747.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037281839.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037274784.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" XP_037282362.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9018519 "TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression" XP_037273626.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037291092.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037281307.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_037280155.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037281535.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_037280800.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_037292179.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037281463.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_037281286.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037286429.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage" XP_037272723.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037286396.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281432.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_037281040.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037278527.1 8 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-6783310;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037291746.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037268059.1 13 MetaCyc: PWY-6672;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5132;MetaCyc: PWY-7118;Reactome: R-HSA-71384;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108 "Cis-genanyl-coa degradation";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Ethanol oxidation";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Methane metabolism";"L-isoleucine biosynthesis V" XP_037282778.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037282953.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-381038 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes" XP_037289818.1 11 Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-389948;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-909733;Reactome: R-HSA-912694;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-9008059;Reactome: R-HSA-432142 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"PD-1 signaling";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Interferon alpha/beta signaling";"Regulation of IFNA signaling";"Costimulation by the CD28 family";"PECAM1 interactions";"Interleukin-37 signaling";"Platelet sensitization by LDL" XP_037289476.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037290875.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037273320.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037283021.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin" XP_037289579.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037281436.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037273147.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037282770.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037271380.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037281210.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037286362.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_037284410.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-909733 "Interferon gamma signaling";"Interferon alpha/beta signaling" XP_037280460.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037281706.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037280967.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277217.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037284482.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037286821.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268645.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037270713.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037284319.1 6 Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8957275 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation" XP_037281277.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_037284598.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037290492.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037288249.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_037278390.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158 "Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V" XP_037279174.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037285324.1 13 KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism" XP_037272364.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_037286503.1 9 MetaCyc: PWY-6964;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2 "Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism" XP_037267986.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037268560.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037286721.1 5 MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22 "Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism" XP_037280789.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA" XP_037283775.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037291858.1 4 MetaCyc: PWY-5028;MetaCyc: PWY-5030;KEGG: 00340+4.3.1.3;Reactome: R-HSA-70921 "L-histidine degradation II";"L-histidine degradation III";"Histidine metabolism";"Histidine catabolism" XP_037281892.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_037288077.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037281044.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037277386.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_037275951.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037277758.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037290776.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037284593.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037274364.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_037288553.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037282900.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037278966.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037283982.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037268446.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_037281247.1 4 KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183 "Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_037271431.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037269238.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_037279056.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037275222.1 13 Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857 "CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation" XP_037278673.1 40 MetaCyc: PWY-7401;MetaCyc: PWY-5109;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5138;MetaCyc: PWY-6583;MetaCyc: PWY-1361;MetaCyc: PWY-7216;MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-7778;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7779;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7656;MetaCyc: PWY-7094;MetaCyc: PWY-6435;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944 "Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"Benzoate degradation";"beta-Alanine metabolism";"Lysine degradation";"Butanoate metabolism";"Fatty acid degradation";"Pyruvate fermentation to butanol II (engineered)";"Tryptophan metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to butanol I";"Benzoyl-coa degradation I (aerobic)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Geraniol degradation";"Aminobenzoate degradation";"alpha-Linolenic acid metabolism";"Limonene and pinene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"2-methylpropene degradation";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Methyl tert-butyl ether degradation";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"4-hydroxybenzoate biosynthesis III (plants)";"Valine, leucine and isoleucine degradation";"Androstenedione degradation" XP_037272029.1 30 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69202;Reactome: R-HSA-199418;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;Reactome: R-HSA-9634638;KEGG: 04150+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-198323;Reactome: R-HSA-6804759;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-389513;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-69656;Reactome: R-HSA-8941332;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Cyclin E associated events during G1/S transition";"Negative regulation of the PI3K/AKT network";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"mTOR signaling pathway";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Activity through Association with Co-factors";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"CTLA4 inhibitory signaling";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX2 regulates genes involved in cell migration";"Relaxin signaling pathway" XP_037283358.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037288366.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037270448.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_037291809.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037274005.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037283166.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037269171.1 8 Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037288939.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037270178.1 10 KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2 "Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism" XP_037289170.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037285277.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037269138.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037287448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037284178.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037273561.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037272124.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_037288203.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037279034.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037268734.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037279348.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037275572.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037272682.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037280289.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037288985.1 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_037284736.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037270477.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037290797.1 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037285914.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037287771.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-8866423 "Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"VLDL clearance";"Chylomicron remodeling";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"VLDL assembly" XP_037268062.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037270150.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861 "Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly" XP_037277494.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037272470.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037281565.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_037278525.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037268422.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037282603.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037274396.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037271823.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression" XP_037288560.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_037288890.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_037277727.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins" XP_037269561.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037289184.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037289149.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)" XP_037285825.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037270004.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037283855.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037285841.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037289896.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037272176.1 7 Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;MetaCyc: PWY-6134 "Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV" XP_037286928.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037284520.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037285940.1 20 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V" XP_037285173.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724 "Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription" XP_037271982.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" XP_037278668.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037285289.1 8 Reactome: R-HSA-2465910;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "MASTL Facilitates Mitotic Progression";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037283772.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037268376.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_037284191.1 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101 "Other glycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation" XP_037276506.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells" XP_037283848.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037268730.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037283116.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037282604.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_037279193.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037286281.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486 "MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis" XP_037278279.1 4 Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22 "Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism" XP_037274295.1 4 Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation" XP_037268489.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037290415.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_037283644.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037269139.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037285729.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_037292049.1 4 Reactome: R-HSA-174577;Reactome: R-HSA-375276;Reactome: R-HSA-977606;Reactome: R-HSA-418594 "Activation of C3 and C5";"Peptide ligand-binding receptors";"Regulation of Complement cascade";"G alpha (i) signalling events" XP_037280774.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events" XP_037279846.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037286410.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_037277802.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037279823.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096 "Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation" XP_037280543.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037288459.1 11 MetaCyc: PWY-7268;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6549;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_037290338.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037283657.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037292075.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037283639.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037269266.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037283873.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037277703.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_037273865.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037277135.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037284400.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037281561.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037285590.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037269782.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037289202.1 42 Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-1912408;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-3214815;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-2559582;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841 "B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"DNA methylation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Pre-NOTCH Transcription and Translation";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HDACs deacetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic recombination";"Cleavage of the damaged purine";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Senescence-Associated Secretory Phenotype (SASP)";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines" XP_037281403.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_037269723.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037274340.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037275135.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_037268005.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037279558.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_037288624.1 18 Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167242 "mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_037268071.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_037276257.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037269178.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_037284378.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037277389.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_037285992.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037285846.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-174411 "Translesion Synthesis by POLH";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere" XP_037285583.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037274146.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_037288331.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_037282546.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037288744.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268018.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037277149.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037291063.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037288453.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037281310.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037280468.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037292051.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_037279167.1 15 MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7218 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_037276885.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism" XP_037279254.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037268131.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_037290679.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_037270006.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037278907.1 7 MetaCyc: PWY-5653;KEGG: 00760+6.3.4.21;Reactome: R-HSA-196807;MetaCyc: PWY-5316;KEGG: 00760+2.4.2.19;MetaCyc: PWY-5381;MetaCyc: PWY-7342 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotine biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Superpathway of nicotine biosynthesis" XP_037271535.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037280337.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_037281002.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037281559.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_037269918.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_037287384.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037282305.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037280284.1 11 Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801 "Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair" XP_037282357.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269623.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037283370.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037273961.1 6 MetaCyc: PWY-7426;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_037271123.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037278564.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport" XP_037282243.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037283043.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_037282560.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176408 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase" XP_037283731.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037272979.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037287916.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037280971.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037288030.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037290057.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037281929.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037287728.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037278845.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037280652.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037276325.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037291703.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037278192.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_037284574.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204 "Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037282709.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037270461.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037277074.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037285209.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037290191.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037291558.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037277430.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467 "Recycling pathway of L1";"Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Mitotic Prometaphase";"Cilium Assembly";"HCMV Early Events";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs" XP_037276537.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037271348.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037283658.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037278062.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037273480.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_037286256.1 3 KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B "Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates" XP_037288055.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037279037.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037274653.1 3 Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426 "Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_037287757.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_037274447.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation" XP_037280223.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037278827.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_037272103.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037282306.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037281284.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_037287301.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037268352.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_037287834.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037288270.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_037278194.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037277952.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037291430.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_037276130.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037268316.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037272028.1 30 Reactome: R-HSA-8948751;Reactome: R-HSA-9634638;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-211163;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;Reactome: R-HSA-199418;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-389357;Reactome: R-HSA-111447;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-6804758;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-69656;Reactome: R-HSA-1257604;Reactome: R-HSA-8941332;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389513;Reactome: R-HSA-392451;Reactome: R-HSA-8876198 "Regulation of PTEN stability and activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"AKT-mediated inactivation of FOXO1A";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"Negative regulation of the PI3K/AKT network";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"CD28 dependent PI3K/Akt signaling";"Activation of BAD and translocation to mitochondria";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Acetylation";"Human immunodeficiency virus 1 infection";"Downregulation of ERBB2:ERBB3 signaling";"Cyclin A:Cdk2-associated events at S phase entry";"PIP3 activates AKT signaling";"RUNX2 regulates genes involved in cell migration";"Relaxin signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"CTLA4 inhibitory signaling";"G beta:gamma signalling through PI3Kgamma";"RAB GEFs exchange GTP for GDP on RABs" XP_037281767.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_037277348.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_037278552.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037268374.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_037287897.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037290122.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037292100.1 2 Reactome: R-HSA-432047;Reactome: R-HSA-432040 "Passive transport by Aquaporins";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037288314.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037288008.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_037273431.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037271263.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037288188.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8963901 "Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"VLDL assembly";"LDL remodeling";"Chylomicron clearance";"Chylomicron assembly";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Retinoid metabolism and transport";"Chylomicron remodeling" XP_037290339.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037268149.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037283955.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037280464.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037273794.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037291079.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-165054 "HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA" XP_037276316.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037291830.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037287541.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670 "MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis" XP_037280347.1 4 KEGG: 00232+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00633+2.3.1.5;Reactome: R-HSA-156582 "Caffeine metabolism";"Drug metabolism - other enzymes";"Nitrotoluene degradation";"Acetylation" XP_037286875.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037289740.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037287507.1 31 MetaCyc: PWY-7664;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-5147;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5989 "Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Stearate biosynthesis II (bacteria and plants)" XP_037281087.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037280221.1 2 Reactome: R-HSA-977606;Reactome: R-HSA-174577 "Regulation of Complement cascade";"Activation of C3 and C5" XP_037274394.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_037278519.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037285969.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037269078.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037280557.1 9 KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112 "Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_037278465.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037291535.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037269464.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_037287135.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037288433.1 6 MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-5067 "Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_037283474.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037281269.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037271894.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037288860.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_037276213.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037271675.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037282503.1 6 Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_037288067.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-9009391 "Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"RET signaling";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling" XP_037289659.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037268317.1 3 KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615;Reactome: R-HSA-1474151 "Folate biosynthesis";"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037280470.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037285883.1 13 MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5 "Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism" XP_037278403.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037274335.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037288280.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones" XP_037272597.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037282750.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037287835.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037281251.1 4 KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1 "Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_037276184.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037272078.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_037288009.1 10 KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153 "Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Phosphatidylinositol signaling system" XP_037279039.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037281221.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_037287937.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037289010.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037276157.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037284869.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037275348.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037271319.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037274183.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_037272496.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_037288286.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037289747.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037270489.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_037278656.1 12 KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing" XP_037281973.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037269925.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" XP_037270780.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638 "VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway" XP_037271790.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_037273774.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037270625.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281646.1 4 MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072 "Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization" XP_037290175.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_037281569.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037276326.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037288535.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037292106.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037275559.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_037277644.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037284132.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037278840.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037279727.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037283164.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037278441.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037286966.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880 "Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases" XP_037272302.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_037276603.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037281168.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_037273710.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037283685.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037273978.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037287335.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_037279249.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_037276424.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037271425.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813 "APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids" XP_037286825.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037276554.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037286163.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037287726.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037277216.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037273197.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037277855.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037282492.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037287463.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037287321.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_037276833.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037288430.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037268819.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037268487.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037282821.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_037269250.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037286936.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690 "SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events" XP_037283846.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037281289.1 7 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037289015.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174411 "Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere" XP_037279942.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037276781.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037285066.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037288403.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037277437.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_037290275.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037277798.1 8 MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7733;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9 "L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_037281477.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037269081.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037284335.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037280276.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037284292.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_037278634.1 3 Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" XP_037269118.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" XP_037277064.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037276875.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037289493.1 26 Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-5617833 "HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Recycling pathway of L1";"Kinesins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Mitotic Prometaphase";"Cilium Assembly" XP_037289789.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037277882.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_037274894.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037279030.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037285251.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037281043.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037272914.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Synthesis of PA" XP_037289534.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5358346 "CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis" XP_037282871.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52 "Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis" XP_037286292.1 14 MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism" XP_037269034.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037272681.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037283038.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037276924.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037276450.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_037280445.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037272012.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037287665.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_037291089.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_037273004.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037278380.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037285939.1 20 KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5392 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II" XP_037283681.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_037286407.1 3 KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" XP_037270323.1 1 Reactome: R-HSA-419771 "Opsins" XP_037282937.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037269622.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037287604.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037273526.1 4 KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037292084.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" XP_037281261.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_037288136.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037286430.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037283115.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037287451.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_037268168.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_037282292.1 4 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis" XP_037291594.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037272141.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_037270777.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638 "mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway" XP_037287369.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398 "Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway" XP_037292128.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037271983.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037277935.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism" XP_037281145.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037277621.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037284750.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037291275.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037285378.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_037281397.1 13 KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-2261;Reactome: R-HSA-196836;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18 "Glutathione metabolism";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Drug metabolism - cytochrome P450" XP_037284707.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719 "TBC/RABGAPs";"RAB geranylgeranylation" XP_037279285.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation" XP_037284326.1 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037277965.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037279054.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_037278851.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037279829.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037283665.1 13 MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;MetaCyc: PWY-8052;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491 "Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"2-arachidonoylglycerol biosynthesis";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"DAP12 signaling" XP_037277061.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_037280057.1 6 Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-5651;KEGG: 00380+1.13.11.6;MetaCyc: PWY-5647;MetaCyc: PWY-6505 "Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"2-nitrobenzoate degradation I";"L-tryptophan degradation XII (Geobacillus)" XP_037270776.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638 "mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway" XP_037274962.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037286640.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_037279314.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_037279287.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037275671.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_037285488.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037280583.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_037269825.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037291980.1 12 Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_037289674.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_037291938.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037291720.1 10 Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-7909 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)" XP_037278900.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037278218.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA" XP_037271665.1 6 KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2 "Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis" XP_037278508.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037284537.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037270234.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037269917.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_037284330.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037270878.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037287769.1 19 Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041 "Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Platelet sensitization by LDL";"VLDL assembly";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Chylomicron assembly";"Chylomicron clearance";"LDL remodeling" XP_037276076.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037284742.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_037279028.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037284627.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" YP_008999526.1 7 Reactome: R-HSA-6799198;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2 "Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation" XP_037279197.1 12 KEGG: 00280+5.1.99.1;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-7854;KEGG: 00630+5.1.99.1;KEGG: 00640+5.1.99.1;MetaCyc: PWY-5741;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-71032;MetaCyc: PWY-8086;KEGG: 00720+5.1.99.1 "Valine, leucine and isoleucine degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Ethylmalonyl-coa pathway";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Propionyl-CoA catabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes" XP_037288477.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_037284527.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_037280866.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_037271728.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037272316.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037284687.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037272493.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-3769402 "Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex" XP_037276931.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_037290401.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_037280233.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037268201.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_037287256.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269549.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037274850.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_037287854.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037287889.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037288917.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037283300.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037285786.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037288355.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-2151201 "RORA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional activation of mitochondrial biogenesis" XP_037281916.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037279158.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037285290.1 8 KEGG: 04151+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"MASTL Facilitates Mitotic Progression";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037270775.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24 "NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway" XP_037292043.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837 "Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation" XP_037276844.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037286105.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_037282749.1 18 KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643 "Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"(R)-cysteate degradation";"Arginine biosynthesis";"Coenzyme M biosynthesis II" XP_037291406.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" XP_037290854.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_037284358.1 5 KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis" XP_037286735.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037276520.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037288967.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037282971.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037282606.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037280786.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367 "Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines" XP_037291713.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037280193.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037285460.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037278937.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037279055.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037271401.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037281293.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037271572.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_037280941.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037274030.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy" XP_037273915.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_037282198.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037284688.1 8 MetaCyc: PWY-6664;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661 "Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_037279019.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037269042.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037275686.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_037287540.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation" XP_037274131.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037291701.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037289906.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037291219.1 8 Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_037282831.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_037271346.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_037278953.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037278890.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037272177.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037279998.1 19 KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086 "Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_037284796.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037290410.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037288222.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037276868.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_037285202.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037278792.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037288365.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_037285207.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037277188.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_037268350.1 1 Reactome: R-HSA-196807 "Nicotinate metabolism" XP_037283638.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590 "Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling" XP_037290246.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037279965.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037276824.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_037284176.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037279035.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037275287.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037289700.1 2 KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" XP_037274014.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037291946.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037274136.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-73728;Reactome: R-HSA-1912408 "Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"Meiotic recombination";"Meiotic synapsis";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation" XP_037273202.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037283700.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037288401.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221 "Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)" XP_037281568.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037282710.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037288491.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037276165.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037270052.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037282446.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037286607.1 18 MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037288415.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_037287039.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037278567.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037291715.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_037270727.1 6 KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_037283460.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037282579.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037288637.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037280752.1 4 KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Arginine and proline metabolism" XP_037286964.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880 "Regulation of TP53 Degradation";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases" XP_037282353.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037286070.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037271845.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037269408.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037275785.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_037279137.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037290055.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037281220.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation" XP_037271232.1 3 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984 "One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation" XP_037280277.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037278732.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_037279080.1 14 Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-1474228 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Degradation of the extracellular matrix" XP_037273420.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037283674.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037277638.1 29 Reactome: R-HSA-167158;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167161 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation" XP_037281563.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037277560.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037287420.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037281902.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037282219.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_037284773.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037278200.1 5 KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation" XP_037268820.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_037286598.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037268160.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_037283274.1 8 Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6 "Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Fructose and mannose metabolism" XP_037276357.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_037290564.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037272684.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037272669.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037284198.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037282211.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding" XP_037273348.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037277767.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037278286.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis" XP_037291246.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601 "GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_037288235.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037283868.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037282625.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037287734.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism" XP_037283600.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801 "POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair" XP_037283588.1 11 Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-3299685 "SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species" XP_037282869.1 9 MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" XP_037275110.1 5 Reactome: R-HSA-9609523;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037280197.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037285600.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_037289687.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7199 "Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage" XP_037291583.1 10 Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-611105 "Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport" XP_037292113.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_037278911.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037279126.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037287139.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037285833.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_037277706.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037276363.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_037281285.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037271821.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_037288925.1 17 MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6 "Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_037277707.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037290180.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037272851.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_037277895.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_037275343.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037290497.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037275003.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037283165.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_037276522.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_037285205.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_037270897.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_037291925.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_037268917.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-877300 "Interferon alpha/beta signaling";"Interferon gamma signaling" XP_037275549.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878 "Recycling pathway of L1";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Mitotic Prometaphase";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport" XP_037279645.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037275119.1 9 MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events" XP_037277202.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037279652.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037288570.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_037279218.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037287367.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128 "Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling" XP_037286745.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation" XP_037270737.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037281977.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037287050.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037289730.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_037283176.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037288978.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037281368.1 3 Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway" XP_037278479.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_037272277.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037286765.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037282427.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037286632.1 3 MetaCyc: PWY-1269;KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Lipopolysaccharide biosynthesis";"Sialic acid metabolism" XP_037277857.1 42 Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-2559582;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-427359 "DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"DNA methylation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"Meiotic recombination";"Meiotic synapsis";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Senescence-Associated Secretory Phenotype (SASP)";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression" XP_037284758.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037280196.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037286683.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037278565.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_037291382.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037271528.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037282221.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-5205685 "Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy" XP_037276472.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037281640.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037282660.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037283607.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037292107.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037280267.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037289711.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_037283418.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037281753.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239 "COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1" XP_037269571.1 9 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-5674135 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"mTORC1-mediated signalling";"MAP2K and MAPK activation" XP_037281352.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037286559.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037277353.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_037287200.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-983231 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Hedgehog 'off' state";"PKA activation";"Factors involved in megakaryocyte development and platelet production" XP_037285142.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159 "Macroautophagy";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling" XP_037291527.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037287224.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_037279376.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" XP_037280287.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"T cell receptor signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_037278577.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037272227.1 7 Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795 "HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_037285263.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037269080.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_037276510.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037281581.1 5 MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7185 "UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I" XP_037272060.1 18 Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4 "Acyl chain remodelling of PI";"Ether lipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Arachidonic acid metabolism" XP_037276525.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_037279181.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037273524.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037284426.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_037283066.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037268051.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_037278568.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037272121.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_037287217.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897 "Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes" XP_037276808.1 6 Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" XP_037277445.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_037286809.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037280372.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037269500.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037287640.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037276535.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037288644.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037277761.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037277354.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_037281274.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_037277476.1 8 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_037274536.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_037271538.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271798.1 5 MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_037278973.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_037276567.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037273517.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037285712.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037270778.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638 "p38MAPK events";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway";"NOD1/2 Signaling Pathway" XP_037276315.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037286239.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037285043.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531 "SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus" XP_037288490.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037278844.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037283065.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_037286904.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037271807.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037283267.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037283817.1 1 Reactome: R-HSA-5687128 "MAPK6/MAPK4 signaling" XP_037273995.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_037289043.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037284411.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037290462.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037271004.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation" XP_037291837.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037278923.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037270877.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037267987.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_037276955.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037278854.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037291783.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_037276879.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037283268.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_037276436.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037277398.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037284716.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037280962.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-165054 "HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA" XP_037284469.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037287203.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_037271573.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315 "Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_037290460.1 52 Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-749476;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-77075 "Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE" XP_037274224.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037289067.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037290047.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037283921.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037274434.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037268899.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037268219.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037277495.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_037272032.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_037278385.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037280808.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037287666.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037268783.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037281541.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037283571.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037275818.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037279044.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037271152.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037273309.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037268073.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_037285974.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037283053.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_037268509.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_037287821.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037276393.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_037277031.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037269192.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037271724.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037282961.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037273878.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037277526.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_037282143.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037275098.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037288724.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037275517.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037269597.1 9 Reactome: R-HSA-3304356;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling" XP_037269458.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037269924.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_037288994.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_037277153.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037282872.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52 "Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis" XP_037273154.1 9 KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18 "Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450" XP_037277050.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation" XP_037282289.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_037285131.1 28 Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-3371453;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of HSF1-mediated heat shock response";"Meiotic recombination";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_037289334.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037275051.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037277375.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037277655.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037287571.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037282826.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037283582.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037273790.1 6 Reactome: R-HSA-4641262;Reactome: R-HSA-381340;Reactome: R-HSA-4086400;Reactome: R-HSA-3238698;Reactome: R-HSA-201681;Reactome: R-HSA-373080 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Transcriptional regulation of white adipocyte differentiation";"PCP/CE pathway";"WNT ligand biogenesis and trafficking";"TCF dependent signaling in response to WNT";"Class B/2 (Secretin family receptors)" XP_037283945.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-983168 "Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037283705.1 2 Reactome: R-HSA-174577;Reactome: R-HSA-977606 "Activation of C3 and C5";"Regulation of Complement cascade" XP_037268038.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_037291204.1 32 Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167243 "Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery" XP_037277871.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037268220.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037286585.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037285267.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037288653.1 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_037287653.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037277980.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037285445.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037278811.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037274432.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037282934.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_037287887.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037282763.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037278954.1 3 Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_037289348.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037282802.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_037289071.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037285054.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037272668.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037289126.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_037278503.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037279104.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037287951.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins" XP_037281280.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037284522.1 6 KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)" XP_037277134.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037268075.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037275599.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_037287380.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037280475.1 4 KEGG: 00633+2.3.1.5;KEGG: 00983+2.3.1.5;KEGG: 00232+2.3.1.5;Reactome: R-HSA-156582 "Nitrotoluene degradation";"Drug metabolism - other enzymes";"Caffeine metabolism";"Acetylation" XP_037272922.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_037289540.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_037277286.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN" XP_037287330.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037268492.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037278669.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037289734.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037272222.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037274530.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037271311.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037281342.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037285264.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037272011.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037273551.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_037289784.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_037271008.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_037272098.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037291458.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_037282258.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5693616;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-3371511;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5655862 "Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK" XP_037271479.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037280644.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_037284119.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037285907.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037284475.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037285769.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037292002.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037290722.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037285372.1 3 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_037281551.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037272037.1 13 MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3 "Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes" XP_037284596.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_037274893.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037290943.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_037287386.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_037281470.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037270814.1 12 KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5856 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_037280795.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553 "Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs" XP_037281775.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037282868.1 9 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation" XP_037291612.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037279184.1 6 MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-4381 "Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_037268536.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037275138.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_037282879.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037284222.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_037272131.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_037275736.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037277423.1 5 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037287903.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037269201.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-4061 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I" XP_037281555.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_037283067.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037276630.1 8 MetaCyc: PWY-7733;MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9 "3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_037271962.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037272183.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037275626.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037283566.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_037271685.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037283595.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037273944.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037268360.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037291758.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037271481.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037290121.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037288397.1 7 MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_037277573.1 1 KEGG: 00982+1.14.13.8 "Drug metabolism - cytochrome P450" XP_037291874.1 56 Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-382556 "Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport" XP_037271527.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037268060.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037286771.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination" XP_037272680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037278339.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037283013.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_037277468.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_037274094.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037269041.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037274835.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037281266.1 10 KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45 "Pyrimidine metabolism";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate" XP_037272024.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_037271183.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037279927.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_037289951.1 25 Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-380270;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434 "Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Mitotic Prometaphase";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037277380.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" XP_037271488.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037278368.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037270087.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_037278541.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_037280609.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037282578.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037288759.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037281346.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037291993.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037288079.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037269113.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037282425.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037291302.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037268998.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_037277279.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_037278504.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037277138.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_037280677.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_037281478.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_037284795.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037278765.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037277897.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_037287803.1 12 Reactome: R-HSA-380972;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Macroautophagy";"mTOR signaling pathway";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection" XP_037276127.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_037288313.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037282084.1 1 MetaCyc: PWY-7883 "Anhydromuropeptides recycling II" XP_037282776.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037282218.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037272699.1 7 Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-69541 "Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53" XP_037270673.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037291243.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037280487.1 14 Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-5620924;Reactome: R-HSA-68877 "HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Intraflagellar transport";"Mitotic Prometaphase" XP_037278246.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037278329.1 33 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-69656;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_037268166.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037278639.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037284923.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037286642.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037283630.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037274357.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037269074.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037288475.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037281174.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037268926.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037277040.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037283734.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037282935.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_037279247.1 56 Reactome: R-HSA-9020702;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128 "Interleukin-1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Neddylation";"UCH proteinases";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling" XP_037289242.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037288616.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037287377.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037268263.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037289455.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037287340.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037286033.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037269269.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037274140.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037282772.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037287028.1 5 KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037268436.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037271734.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037287829.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037269766.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037275603.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037278052.1 12 Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-912446 "HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination" XP_037276913.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037279855.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_037276355.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037286285.1 17 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;KEGG: 00970+6.1.1.1;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aminoacyl-tRNA biosynthesis";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" XP_037284296.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037283800.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037269877.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037277939.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_037289307.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_037287861.1 13 Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-5362768;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-6798695;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895 "HSF1 activation";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"Neutrophil degranulation";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Protein methylation";"Defective CFTR causes cystic fibrosis" XP_037283641.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037268313.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037271990.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037289838.1 42 Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110330;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "DNA methylation";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"Cleavage of the damaged purine";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected purine";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_037281047.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037274233.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037286238.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037280747.1 6 Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803 "Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" YP_008999535.1 7 MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;Reactome: R-HSA-6799198;MetaCyc: PWY-4302 "Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Oxidative phosphorylation";"Fe(II) oxidation";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)" XP_037285419.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037277278.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_037268055.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037277973.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037291977.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_037283205.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-6610;MetaCyc: PWY-7805;MetaCyc: PWY-6605 "Neutrophil degranulation";"Purine salvage";"Purine metabolism";"Glyphosate degradation III";"Adenine salvage";"(aminomethyl)phosphonate degradation";"Adenine and adenosine salvage II" XP_037281928.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037285623.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037277000.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037280706.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis" XP_037283385.1 8 Reactome: R-HSA-6787639;MetaCyc: PWY-66;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738 "GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis" XP_037290995.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037285446.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037269501.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037269580.1 33 MetaCyc: PWY-7396;MetaCyc: PWY-7798;MetaCyc: PWY-6333;MetaCyc: PWY-5480;MetaCyc: PWY-7013;MetaCyc: PWY-6802;MetaCyc: PWY-5079;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7118;MetaCyc: PWY-5082;MetaCyc: PWY-5076;KEGG: 00010+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-1801;Reactome: R-HSA-71384;MetaCyc: PWY-5751;MetaCyc: PWY-5057;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-6587;KEGG: 00680+1.1.1.284;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-7111;KEGG: 00830+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6871 "Butanol and isobutanol biosynthesis (engineered)";"Protein S-nitrosylation and denitrosylation";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol I";"(S)-propane-1,2-diol degradation";"Salidroside biosynthesis";"L-phenylalanine degradation III";"Tyrosine metabolism";"Pyruvate fermentation to ethanol II";"Chitin degradation to ethanol";"L-methionine degradation III";"L-leucine degradation III";"Glycolysis / Gluconeogenesis";"Fatty acid degradation";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Naphthalene degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Ethanol oxidation";"Phenylethanol biosynthesis";"L-valine degradation II";"alpha-Linolenic acid metabolism";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol III";"Methane metabolism";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Glycine, serine and threonine metabolism";"L-isoleucine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"Retinol metabolism";"Metabolism of xenobiotics by cytochrome P450";"3-methylbutanol biosynthesis (engineered)" XP_037277484.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037291194.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037289290.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037287704.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037268424.1 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_037290391.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597 "Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events" XP_037271233.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037282029.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037289068.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037284800.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037278531.1 179 Reactome: R-HSA-1169091;Reactome: R-HSA-9615710;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6807004;Reactome: R-HSA-6804760;Reactome: R-HSA-450302;Reactome: R-HSA-179409;Reactome: R-HSA-3134975;Reactome: R-HSA-8876493;Reactome: R-HSA-2173791;Reactome: R-HSA-3785653;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-975957;Reactome: R-HSA-5689877;Reactome: R-HSA-1253288;Reactome: R-HSA-209560;Reactome: R-HSA-5610780;Reactome: R-HSA-168928;Reactome: R-HSA-917937;Reactome: R-HSA-75815;Reactome: R-HSA-5696395;Reactome: R-HSA-9014325;Reactome: R-HSA-201681;Reactome: R-HSA-5655862;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-162588;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-2644606;Reactome: R-HSA-937042;Reactome: R-HSA-2691232;Reactome: R-HSA-2408557;Reactome: R-HSA-174154;Reactome: R-HSA-2559580;Reactome: R-HSA-174184;Reactome: R-HSA-8866652;Reactome: R-HSA-195253;Reactome: R-HSA-72689;Reactome: R-HSA-2894862;Reactome: R-HSA-6782135;Reactome: R-HSA-5357905;Reactome: R-HSA-2979096;Reactome: R-HSA-5693607;Reactome: R-HSA-975144;Reactome: R-HSA-917729;Reactome: R-HSA-937072;Reactome: R-HSA-8875360;Reactome: R-HSA-8941858;Reactome: R-HSA-6783310;Reactome: R-HSA-2672351;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-2173796;Reactome: R-HSA-5689901;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-5696397;Reactome: R-HSA-977225;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-8849469;Reactome: R-HSA-156902;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-6791226;Reactome: R-HSA-5654733;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-1169408;Reactome: R-HSA-9645460;Reactome: R-HSA-6781823;Reactome: R-HSA-5675482;Reactome: R-HSA-5610785;Reactome: R-HSA-3322077;Reactome: R-HSA-382556;Reactome: R-HSA-975110;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-2559582;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-975163;Reactome: R-HSA-5654727;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-72706;Reactome: R-HSA-5676590;Reactome: R-HSA-912631;Reactome: R-HSA-202424;Reactome: R-HSA-400253;Reactome: R-HSA-1358803;Reactome: R-HSA-1799339;Reactome: R-HSA-2173795;Reactome: R-HSA-450321;Reactome: R-HSA-175474;Reactome: R-HSA-5654726;Reactome: R-HSA-2173788;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-8856828;Reactome: R-HSA-936964;Reactome: R-HSA-9033241;Reactome: R-HSA-69541;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-182971;Reactome: R-HSA-936440;Reactome: R-HSA-4641263;Reactome: R-HSA-205043;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-9636383;Reactome: R-HSA-174084;Reactome: R-HSA-5654732;Reactome: R-HSA-69017;Reactome: R-HSA-9613829;Reactome: R-HSA-2122947;Reactome: R-HSA-2559585;Reactome: R-HSA-450408;Reactome: R-HSA-445989;Reactome: R-HSA-3769402;Reactome: R-HSA-901032;Reactome: R-HSA-5693565;Reactome: R-HSA-174048;Reactome: R-HSA-1236382;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-156827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-5205685;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-209543;Reactome: R-HSA-6804757;Reactome: R-HSA-5685942;Reactome: R-HSA-2565942;Reactome: R-HSA-8948747;Reactome: R-HSA-349425;Reactome: R-HSA-937039;Reactome: R-HSA-6781827;Reactome: R-HSA-168927;Reactome: R-HSA-9020702;Reactome: R-HSA-9637628;Reactome: R-HSA-5357956;Reactome: R-HSA-5668541;Reactome: R-HSA-937041;Reactome: R-HSA-72764;Reactome: R-HSA-8939236;Reactome: R-HSA-5689896;Reactome: R-HSA-9633012;Reactome: R-HSA-4608870;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-9013973;Reactome: R-HSA-69601 "Activation of NF-kappaB in B cells";"Late endosomal microautophagy";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Negative regulation of MET activity";"Regulation of TP53 Activity through Methylation";"activated TAK1 mediates p38 MAPK activation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of innate immune responses to cytosolic DNA";"InlA-mediated entry of Listeria monocytogenes into host cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Myoclonic epilepsy of Lafora";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Josephin domain DUBs";"Downregulation of ERBB4 signaling";"NF-kB is activated and signals survival";"Degradation of GLI1 by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Iron uptake and transport";"Ubiquitin-dependent degradation of Cyclin D";"Formation of Incision Complex in GG-NER";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TCF dependent signaling in response to WNT";"Translesion synthesis by POLK";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Budding and maturation of HIV virion";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"IRAK2 mediated activation of TAK1 complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Selenocysteine synthesis";"APC/C:Cdc20 mediated degradation of Securin";"Oxidative Stress Induced Senescence";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of beta-catenin by the destruction complex";"Formation of a pool of free 40S subunits";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Dual incision in TC-NER";"Regulation of TNFR1 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Processing of DNA double-strand break ends";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of RUNX3 expression and activity";"Fanconi Anemia Pathway";"Stimuli-sensing channels";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Metalloprotease DUBs";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Amyloid fiber formation";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Peptide chain elongation";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulation of FGFR4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"ISG15 antiviral mechanism";"Alpha-protein kinase 1 signaling pathway";"Formation of TC-NER Pre-Incision Complex";"Regulation of necroptotic cell death";"GLI3 is processed to GLI3R by the proteasome";"Glycogen synthesis";"ABC-family proteins mediated transport";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Senescence-Associated Secretory Phenotype (SASP)";"UCH proteinases";"Neddylation";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR2 signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Spry regulation of FGF signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NIK-->noncanonical NF-kB signaling";"Regulation of signaling by CBL";"Downstream TCR signaling";"Circadian Clock";"Downregulation of ERBB2:ERBB3 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Assembly Of The HIV Virion";"Negative regulation of FGFR1 signaling";"Downregulation of TGF-beta receptor signaling";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Clathrin-mediated endocytosis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Peroxisomal protein import";"Stabilization of p53";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"EGFR downregulation";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of FZD by ubiquitination";"NRIF signals cell death from the nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Prevention of phagosomal-lysosomal fusion";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of FGFR3 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Chaperone Mediated Autophagy";"NOTCH1 Intracellular Domain Regulates Transcription";"Oncogene Induced Senescence";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Deactivation of the beta-catenin transactivating complex";"ER Quality Control Compartment (ERQC)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"APC/C:Cdc20 mediated degradation of Cyclin B";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Pink/Parkin Mediated Mitophagy";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"p75NTR recruits signalling complexes";"Regulation of TP53 Degradation";"HDR through Homologous Recombination (HRR)";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of PTEN localization";"Autodegradation of the E3 ubiquitin ligase COP1";"IRAK1 recruits IKK complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TICAM1, RIP1-mediated IKK complex recruitment";"Interleukin-1 signaling";"Modulation by Mtb of host immune system";"TNFR1-induced NFkappaB signaling pathway";"TNFR2 non-canonical NF-kB pathway";"IKK complex recruitment mediated by RIP1";"Eukaryotic Translation Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ovarian tumor domain proteases";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Asymmetric localization of PCP proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_037284788.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_037277739.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_037284550.1 5 Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2871796 "Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation" XP_037274899.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037278658.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-7783 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation" XP_037287255.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472 "Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037288135.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_037278431.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" XP_037285689.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037268120.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037286286.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037289995.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037281038.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_037278963.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037281218.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037276746.1 7 Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;MetaCyc: PWY-5188 "Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_037286361.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037273164.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037271144.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_037277296.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037280184.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037284512.1 6 Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037274583.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037286221.1 11 KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway" XP_037279631.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037279173.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_037270055.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037275511.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037282662.1 5 Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-4793954 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_037277001.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" YP_008999530.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037285118.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037285208.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037284399.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037290166.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_037277123.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037276451.1 14 MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" XP_037277192.1 18 MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_037272704.1 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;MetaCyc: PWY-5723 "Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt" XP_037289668.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_037270056.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037286824.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-174417 "HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis" XP_037273956.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Th1 and Th2 cell differentiation" XP_037272129.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037286159.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037281288.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_037288212.1 57 Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837 "Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"UCH proteinases";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation" XP_037287902.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037276118.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_037275527.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037284600.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-446199 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate" XP_037277100.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_037272002.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase" XP_037278310.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037283278.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-532668;Reactome: R-HSA-901032 "Protein ubiquitination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ER Quality Control Compartment (ERQC)" XP_037286327.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037281203.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037284334.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037284547.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037284863.1 3 Reactome: R-HSA-5578995;KEGG: 00983+2.1.1.67;Reactome: R-HSA-156581 "Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)";"Drug metabolism - other enzymes";"Methylation" XP_037272925.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037281431.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_037290804.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037287940.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037280490.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037278373.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_037280110.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_037277150.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037285945.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_037272958.1 6 MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)" XP_037285771.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_037269258.1 5 Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_037283716.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037278507.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037268202.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_037288223.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037291128.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_037272921.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037277928.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037279350.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037280178.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037269502.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-382556 "CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"Neddylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport" XP_037287382.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037284367.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_037278713.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037286316.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037287656.1 4 Reactome: R-HSA-1362409;MetaCyc: PWY-7250;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism" XP_037291735.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037285628.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_037274308.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037279057.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037271195.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_037287258.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_037277989.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037270330.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037274070.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037282018.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_037269867.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482 "FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation" XP_037291300.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037284495.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037277311.1 8 Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Gap junction degradation" XP_037292148.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037281324.1 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" XP_037281604.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037279850.1 6 MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism" XP_037271313.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037272793.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037277508.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037282777.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037284329.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037268197.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037277226.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037275151.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037280881.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_037269934.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037270228.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_037279507.1 5 KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism" XP_037273882.1 4 Reactome: R-HSA-196843;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Vitamin B2 (riboflavin) metabolism";"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_037285730.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_037292058.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037280204.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_037274182.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_037287178.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037271241.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037277219.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037279045.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037281437.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037278572.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037282837.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_037289330.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037287058.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-76005 "WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+" XP_037282181.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037274881.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_037269120.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs" XP_037278262.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037279494.1 7 Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838 "Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Activation of SMO" XP_037268130.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037270252.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_037291678.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037275111.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037279286.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_037271442.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037287799.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_037273184.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037288984.1 6 MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism" XP_037275187.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037288907.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253 "Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock" XP_037269489.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037275565.1 11 Reactome: R-HSA-3359469;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00270+2.1.1.13;Reactome: R-HSA-1614635;MetaCyc: PWY-7977;KEGG: 00670+2.1.1.13;KEGG: 00450+2.1.1.13;Reactome: R-HSA-3359467;Reactome: R-HSA-196741;Reactome: R-HSA-156581 "Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Folate transformations I";"Folate transformations II (plants)";"Cysteine and methionine metabolism";"Sulfur amino acid metabolism";"L-methionine biosynthesis IV (archaea)";"One carbon pool by folate";"Selenocompound metabolism";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Methylation" XP_037274365.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037278543.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_037289934.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_037282936.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_037288431.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037284868.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_037278443.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037277068.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037284214.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037277416.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037282873.1 9 KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)" XP_037274540.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_037281763.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_037276704.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037269884.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037272512.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_037274592.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037287493.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037275043.1 4 Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037269083.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification" XP_037268743.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037271199.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_037282746.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037285830.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037279649.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_037269356.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_037274606.1 30 Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-2564830;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-6782210 "RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cytosolic iron-sulfur cluster assembly";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_037288765.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037282098.1 4 Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00380+3.7.1.3;MetaCyc: PWY-5651 "Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_037273181.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037281580.1 5 MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177 "UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II" XP_037283723.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037271678.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_037281987.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037287932.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037284908.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037279438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037285610.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037289317.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037277653.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_037276370.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_037280059.1 14 Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-68877 "HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"COPI-mediated anterograde transport";"Mitotic Prometaphase" XP_037280945.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037268152.1 7 MetaCyc: PWY-5097;MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;Reactome: R-HSA-389661;MetaCyc: PWY-2941 "L-lysine biosynthesis VI";"L-lysine biosynthesis III";"Lysine biosynthesis";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"Glyoxylate metabolism and glycine degradation";"L-lysine biosynthesis II" XP_037284752.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037272066.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037284368.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037284280.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037272234.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776 "Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_037289459.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037268221.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037281635.1 4 Reactome: R-HSA-3359475;Reactome: R-HSA-71032;Reactome: R-HSA-196741;Reactome: R-HSA-3359478 "Defective MMAA causes methylmalonic aciduria type cblA";"Propionyl-CoA catabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MUT causes methylmalonic aciduria mut type" XP_037281696.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_037271904.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037279457.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037285361.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037271216.1 13 KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;Reactome: R-HSA-71384;KEGG: 00630+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;MetaCyc: PWY-5132 "Methane metabolism";"L-isoleucine biosynthesis V";"Ethanol oxidation";"Glyoxylate and dicarboxylate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis" XP_037285635.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037288918.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037288536.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037269106.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037276125.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_037268960.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037283721.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037285872.1 14 Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167242 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_037286787.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_037280613.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_037281202.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037287450.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037272396.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism" XP_037286456.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_037287955.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037283892.1 4 KEGG: 00220+3.5.1.5;KEGG: 00230+3.5.1.5;MetaCyc: PWY-5704;KEGG: 00791+3.5.1.5 "Arginine biosynthesis";"Purine metabolism";"Urea degradation II";"Atrazine degradation" XP_037278489.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_037280489.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037277133.1 12 MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5857 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_037283462.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_037274326.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_037277900.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_037270620.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037291062.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Hedgehog 'off' state";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_037269608.1 5 MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037278847.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_037281827.1 18 MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism" XP_037267999.1 15 Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence" XP_037291115.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_037282798.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_037268423.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037276074.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037286480.1 9 MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2 "Ammonia assimilation cycle II";"Arginine biosynthesis";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism" XP_037269632.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037289827.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-427413;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571 "Meiotic recombination";"Cleavage of the damaged purine";"Meiotic synapsis";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"DNA methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)" XP_037282434.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037283163.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_037289107.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037286836.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism" XP_037272130.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_037285971.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037285898.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection" XP_037289198.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037279124.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" XP_037272336.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_037284592.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037274431.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037290733.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037279187.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_037288990.1 6 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism" XP_037281345.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037270808.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037272175.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"Folate biosynthesis" XP_037268004.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037286471.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037287368.1 16 Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897 "Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes" XP_037284415.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037289321.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842 "4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II" XP_037286517.1 31 MetaCyc: PWY-7664;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7723;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5147;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;Reactome: R-HSA-163765;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7746;Reactome: R-HSA-75105;MetaCyc: PWY-8049;MetaCyc: PWY-5973;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-5142 "Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Oleate biosynthesis I (plants)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway" XP_037268167.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037282014.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_037285326.1 13 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation" XP_037279611.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037284562.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037273834.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037277914.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075;MetaCyc: PWY-7375 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I" XP_037284544.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037288325.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037288556.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" XP_037288620.1 7 Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6367 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_037287899.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_037270622.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037276516.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037274852.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037278553.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037284733.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_037291192.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037284828.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_037291828.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037272321.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037277846.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_037270094.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037280740.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037284046.1 13 Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"PI3K-Akt signaling pathway";"Signaling by BRAF and RAF fusions";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human cytomegalovirus infection";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection" XP_037290179.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037279849.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25 "Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037268141.1 6 MetaCyc: PWY-5663;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-7442 "Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis" XP_037279822.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037279183.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037279276.1 5 Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37 "DNA methylation";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism" XP_037269377.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037279695.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037281867.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_037288988.1 13 Reactome: R-HSA-4085001;MetaCyc: PWY-6807;Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23 "Sialic acid metabolism";"Xyloglucan degradation II (exoglucanase)";"MPS IV - Morquio syndrome B";"Galactose metabolism";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Other glycan degradation" XP_037276988.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-5689880 "Methylation";"Ub-specific processing proteases" XP_037269548.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037283429.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_037271249.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037272951.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037289181.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037281373.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_037276515.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels"